公开(公告)号：US4539992A

公开(公告)日：1985-09-10

申请号：US486157

申请日：1983-04-25

申请人： Richard V. Calfee ,  Robert N. Bertasz ,  Reese S. Terry, Jr. ,  Pat L. Gordon ,  Ross G. Baker, Jr.

发明人： Richard V. Calfee ,  Robert N. Bertasz ,  Reese S. Terry, Jr. ,  Pat L. Gordon ,  Ross G. Baker, Jr.

IPC分类号： A61N1/372 ,  A61N1/36

CPC分类号： A61N1/3727 ,  A61N1/37223

摘要： An external command device and an internal decoding and verification device are used to non-invasively alter the operating parameters of a programmable device implanted in an animal body. Thus, physiological changes can be easily accommodated by the implanted device. In a preferred embodiment, pulse position modulation is used to externally encode the command information. A resulting string of current pulses generates voltage spikes (in the internal decoding device) through inductively coupled coils. Each incoming data bit is verified and the entire command word is verified. After verification, the decoded command is transferred to a command register for simultaneously altering the selected operating parameters. The internal receiver circuitry may conveniently utilize energy from the induced voltage spike, using passive components for forming an output suitable for processing.

摘要翻译： 使用外部命令装置和内部解码和验证装置非侵入地改变植入动物体内的可编程装置的操作参数。 因此，植入装置可容易地适应生理变化。 在优选实施例中，使用脉冲位置调制来对命令信息进行外部编码。 所产生的电流脉冲串通过电感耦合线圈产生电压尖峰（在内部解码装置中）。 每个输入数据位被验证，并且整个命令字被验证。 验证后，将解码的命令传送到命令寄存器，以同时更改所选择的操作参数。 内部接收器电路可以方便地利用来自感应电压尖峰的能量，使用无源部件来形成适于处理的输出。

公开(公告)号：US5974339A

公开(公告)日：1999-10-26

申请号：US979059

申请日：1997-11-26

申请人： Ross G. Baker, Jr. ,  Pat L. Gordon

发明人： Ross G. Baker, Jr. ,  Pat L. Gordon

IPC分类号： A61N1/39

CPC分类号： A61N1/3956 ,  A61N1/3937 ,  A61N1/3912

摘要： A defibrillator for providing a constant low pulsed current to a patient's heart has a high voltage capacitor for storing electrical energy. An inductor connected to the capacitor smooths out the discharge curve and produces a low current low frequency defibrillator pulse supplied to a patient's heart. The pulse is usually biphasic.

摘要翻译： 用于向患者心脏提供恒定的低脉冲电流的除颤器具有用于存储电能的高电压电容器。 连接到电容器的电感器平滑放电曲线，并产生提供给患者心脏的低电流低频除颤器脉冲。 脉冲通常是双相的。

公开(公告)号：US4404972A

公开(公告)日：1983-09-20

申请号：US264670

申请日：1981-05-18

申请人： Pat L. Gordon ,  Richard V. Calfee ,  Jay Miner

发明人： Pat L. Gordon ,  Richard V. Calfee ,  Jay Miner

IPC分类号： A61N1/37 ,  A61N1/372 ,  G06F1/32 ,  A61N1/36

CPC分类号： A61N1/37276 ,  A61N1/37 ,  G06F1/3228

摘要： An improved body function assistance device is provided wherein a microprocessor controls the response of the device to various external physiological events and internal timer events. The microprocessor is adapted for use with the limited energy supply available from a battery by activating internal logic components of the processor only in response to selected events and to perform an operating routine corresponding to the "wakeup" event. At the end of the operating routine, a new set of wakeup events is selected and the internal logic components are deactivated. A further reduction in the average operating current is obtained by providing a plurality of counting rates to minimize the number of state changes during counting cycles. The microprocessor may be provided with a fixed operating routine or may be provided with the capability of actually introducing program changes in the implanted device.

公开(公告)号：US06895278B1

公开(公告)日：2005-05-17

申请号：US09466387

申请日：1999-12-17

申请人： Pat L. Gordon

发明人： Pat L. Gordon

IPC分类号： A61N1/05 ,  A61N1/36

CPC分类号： A61N1/36007

摘要： Apparatus and method for stimulating neuromuscular tissue in the stomach. The neuromuscular stimulator stimulates the neuromuscular tissue by applying current-controlled electrical pulses. A voltage sensor detects the voltage across the neuromuscular tissue to determine if the voltage meets a predetermined voltage threshold. A control circuit adjusts the current-controlled pulse if the voltage is found to meet the voltage threshold, such that the voltage does not exceed the voltage threshold. A voltage-controlled pulse may also be applied to the tissue. A current sensor would then detect whether the current on the neuromuscular tissue meets a predetermined current threshold, and a control circuit adjusts the voltage controlled pulse such that the current does not exceed the current threshold. A real time clock may be provided which supplies data corresponding to the time of day during the treatment period. A programmable calendar stores parameters of the stimulating pulse, wherein the parameters have a reference to the time of day.

摘要翻译： 用于刺激胃中神经肌肉组织的装置和方法。 神经肌肉刺激器通过施加电流控制的电脉冲刺激神经肌肉组织。 电压传感器检测神经肌肉组织上的电压，以确定电压是否达到预定的电压阈值。 如果发现电压达到电压阈值，则控制电路调节电流控制脉冲，使得电压不超过电压阈值。 电压控制的脉冲也可以施加到组织。 电流传感器然后将检测神经肌肉组织上的电流是否达到预定电流阈值，并且控制电路调节电压控制脉冲，使得电流不超过电流阈值。 可以提供实时时钟，该实时时钟提供对应于治疗期间的时间的数据。 可编程日历存储刺激脉冲的参数，其中参数具有对时间的参考。

公开(公告)号：US06542776B1

公开(公告)日：2003-04-01

申请号：US09466731

申请日：1999-12-17

申请人： Pat L. Gordon ,  David A. Jenkins

发明人： Pat L. Gordon ,  David A. Jenkins

IPC分类号： A61N136

CPC分类号： A61N1/36007 ,  A61N1/05 ,  A61N1/0558

摘要： Apparatus for stimulating neuromuscular tissue of the gastrointestinal tract and methods for installing the apparatus to the neuromuscular tissue. Four electrodes are supported by an electrode assembly for attachment to the neuromuscular tissue. The electrodes are oriented substantially equidistantly with respect to the tissue and provide an electrical interface with the neuromuscular tissue. The pulse generator is provided with a switching matrix, and may stimulate the tissue in a time-varying manner by selecting pairs of electrodes and altering the polarities thereof while stimulating the tissue.

摘要翻译： 用于刺激胃肠道神经肌肉组织的装置以及将该装置安装到神经肌肉组织的方法。 四个电极由用于附着到神经肌肉组织的电极组件支撑。 电极相对于组织基本上等距离地定向，并提供与神经肌肉组织的电接口。 脉冲发生器设置有开关矩阵，并且可以通过选择电极对并在刺激组织的同时改变其极性而以时变的方式刺激组织。

公开(公告)号：US5336253A

公开(公告)日：1994-08-09

申请号：US21408

申请日：1993-02-23

申请人： Pat L. Gordon ,  John T. Meador ,  John G. Keimel ,  Rahul Mehra

发明人： Pat L. Gordon ,  John T. Meador ,  John G. Keimel ,  Rahul Mehra

IPC分类号： A61N1/05

CPC分类号： A61N1/056

摘要： A combined pacing and cardioversion lead system with internal electrical switching components for unipolar or bipolar sensing of electrograms, pacing at normal pacing voltages and cardioversion or defibrillation. In bipolar embodiments, an indifferent electrode, closely spaced to a sensing and pacing electrode, is coupled in common through the integral switching circuitry to a large surface area cardioversion electrode. In these embodiments, pacing and sensing is accomplished through a pair of conductors extending through the lead system to the closely spaced active and indifferent electrode pair. When cardioversion energy is applied to the indifferent electrode, the cardioversion energy is also directed to the cardioversion electrode through operation of the switching circuitry in response to the magnitude of the applied cardioversion pulse. In unipolar embodiments, a distal sensing and pacing electrode is coupled through integral switching circuitry to a large surface area cardioversion electrode. In these embodiments, only a single conductor extending through the lead to the pacing and sensing electrode is required. When cardioversion energy is applied to the pacing and sensing electrode, the cardioversion energy is also directed to the cardioversion electrode through operation of the switching circuitry in response to the magnitude of the applied cardioversion pulse.

摘要翻译： 组合起搏和心律转复引导系统，具有用于单极或双极感测电描记图，起搏正常起搏电压和心脏复律或除颤的内部电气开关组件。 在双极实施例中，与感测和起搏电极紧密隔开的无关电极通过整体开关电路共同耦合到大表面积的复律电极。 在这些实施例中，起搏和感测通过一对延伸穿过导线系统的导体实现到紧密间隔的有源和无关电极对。 当心脏复律能量被施加到无关电极时，响应于所应用的心脏复律脉冲的幅度，复律能量也通过开关电路的操作而被引导到心脏复律电极。 在单极实施例中，远端感测和起搏电极通过整体开关电路耦合到大表面积的心脏复律电极。 在这些实施例中，仅需要将穿过引线延伸到起搏和感测电极的单个导体。 当心律转换能量被施加到起搏和感测电极时，响应于所应用的心律转复脉冲的幅度，复律能量也通过开关电路的操作而被引导到心脏复律电极。

公开(公告)号：US06684104B2

公开(公告)日：2004-01-27

申请号：US10189120

申请日：2002-07-02

申请人： Pat L. Gordon ,  David A. Jenkins

发明人： Pat L. Gordon ,  David A. Jenkins

IPC分类号： A61N136

CPC分类号： A61N1/05 ,  A61N1/0558 ,  A61N1/36007

摘要： Apparatus for stimulating neuromuscular tissue of the gastrointestinal tract and methods for installing the apparatus to the neuromuscular tissue. The pulse generator is provided with a switching matrix, and may stimulate the tissue in a time-varying manner by selecting pairs of electrodes and altering the polarities thereof while stimulating the tissue. In addition, a real-time clock allowing a trigger for on and off modes, the time clock could also allow for a trigger to change parameters. Such parameters that could be changed are pulse width, amplitude, duty cycle (amount of time of pulse and time between pulses, or series of pulses), frequency, polarity, choice of unipolar versus bi-polar, and electrode on-off. The electrical stimulation utilizes a plurality of electrodes connected to at least one organ in the gastrointestinal tract of a patient along a peristaltic flow path with each of the electrodes being connected at a different location along the peristaltic flow path. Electrical pulses are provided to the organ from a first set of the plurality of electrodes and second electrical pulses are provided to the organ from a second set of electrodes. The electrical pulses provided are in an independent non-phased relationship for maintaining therapeutic regulation of peristaltic flow through the at least one organ in the gastrointestinal tract while defeating the body's natural tendency for adaption.

摘要翻译： 用于刺激胃肠道神经肌肉组织的装置以及将该装置安装到神经肌肉组织的方法。 脉冲发生器设置有开关矩阵，并且可以通过选择电极对并在刺激组织的同时改变其极性而以时变的方式刺激组织。 另外，实时时钟允许触发开关模式，时钟也可以允许触发器改变参数。 可以改变的这些参数是脉冲宽度，幅度，占空比（脉冲时间和脉冲之间的时间量或脉冲串），频率，极性，单极性与双极性的选择以及电极开 - 关。 电刺激使用多个电极，其沿着蠕动流动路径连接到患者的胃肠道中的至少一个器官，其中每个电极沿着蠕动流动路径连接在不同的位置。 电脉冲从第一组多个电极提供给器官，并且第二电脉冲从第二组电极提供给器官。 提供的电脉冲处于独立的非相位关系，用于维持蠕动流动通过胃肠道中的至少一个器官的治疗调节，同时击败身体的自然适应趋势。

公开(公告)号：US4553548A

公开(公告)日：1985-11-19

申请号：US524851

申请日：1983-08-19

申请人： Anthony J. Varrichio ,  Pat L. Gordon

发明人： Anthony J. Varrichio ,  Pat L. Gordon

IPC分类号： A61N1/08 ,  A61N1/36 ,  A61N1/00

CPC分类号： A61N1/36035 ,  A61N1/08

摘要： An interrogator for remotely interrogating an internal counter of a scoliosis treatment device. An internal counter of the treatment device is incremented for those periods of time in which the treatment level of the device is in excess of a compliance level. The interrogator communicates with the internal counter by means of two serial data lines. On one data line the interrogator generates a clock signal to the internal counter for incrementing the device and on the other data line the interrogator receives a pulse indicating the internal counter has overflowed. By incrementing the internal counter through a full cycle of its maximum count the counter will retain the count present when it is interrogated. Additionally, by counting the number of, clock counts comprising the period from the overflow signal to the end of a full cycle a duplication of the count in the remote internal counter can be stored in the interrogator and subsequently displayed.

摘要翻译： 用于远程询问脊柱侧弯治疗装置的内部计数器的询问器。 治疗装置的内部计数器在设备的治疗水平超过合规水平的那段时间内递增。 询问器通过两条串行数据线与内部计数器通信。 在一条数据线上，询问器产生一个时钟信号给内部计数器，用于递增器件，另一条数据线上，询问器接收一个指示内部计数器溢出的脉冲。 通过在其最大计数的整个周期内递增内部计数器，计数器将保留当询问时存在的计数。 此外，通过计数包括从溢出信号到完整周期结束的周期的时钟计数的数量，远程内部计数器中的计数的重复可以存储在询问器中并随后显示。

公开(公告)号：US07292889B2

公开(公告)日：2007-11-06

申请号：US10999515

申请日：2004-11-30

申请人： Pat L. Gordon

发明人： Pat L. Gordon

IPC分类号： A61N1/36

CPC分类号： A61N1/36007

摘要： Apparatus and method for stimulating neuromuscular tissue in the stomach. The neuromuscular stimulator stimulates the neuromuscular tissue by applying current-controlled electrical pulses. A voltage sensor detects the voltage across the neuromuscular tissue to determine if the voltage meets a predetermined voltage threshold. A control circuit adjusts the current-controlled pulse if the voltage is found to meet the voltage threshold, such that the voltage does not exceed the voltage threshold. A voltage-controlled pulse may also be applied to the tissue. A current sensor would then detect whether the current on the neuromuscular tissue meets a predetermined current threshold, and a control circuit adjusts the voltage-controlled pulse such that the current does not exceed the current threshold. A real time clock may be provided which supplies data corresponding to the time of day during the treatment period. A programmable calendar stores parameters of the stimulating pulse, wherein the parameters have a reference to the time of day.

摘要翻译： 用于刺激胃中神经肌肉组织的装置和方法。 神经肌肉刺激器通过施加电流控制的电脉冲刺激神经肌肉组织。 电压传感器检测神经肌肉组织上的电压，以确定电压是否达到预定的电压阈值。 如果发现电压达到电压阈值，则控制电路调节电流控制脉冲，使得电压不超过电压阈值。 电压控制的脉冲也可以施加到组织。 然后，电流传感器将检测神经肌肉组织上的电流是否达到预定电流阈值，并且控制电路调节电压控制脉冲，使得电流不超过电流阈值。 可以提供实时时钟，该实时时钟提供对应于治疗期间的时间的数据。 可编程日历存储刺激脉冲的参数，其中参数具有对时间的参考。

公开(公告)号：US4633311A

公开(公告)日：1986-12-30

申请号：US467312

申请日：1983-02-17

申请人： Pat L. Gordon ,  Barin G. Haskell ,  Robert L. Schmidt

发明人： Pat L. Gordon ,  Barin G. Haskell ,  Robert L. Schmidt

IPC分类号： H04N7/08 ,  H04N7/12

CPC分类号： H04N7/0806

摘要： The bandwidth required for a regularly occurring signal such as a television signal, as received from a signal source can be substantially reduced by not transmitting each and every one of the horizontal scan lines. Rather, firstly, one or more selected lines may be transmitted and, secondly, instead of transmitting the remaining, unselected lines, a signal representing a predetermined arithmetic difference among predetermined ones of the scan lines may be transmitted.

摘要翻译： 通过不传输水平扫描线中的每一个，可以显着地减少从信号源接收的诸如电视信号的规律发生的信号所需的带宽。 相反，首先，可以发送一个或多个所选行，其次，可以发送表示预定扫描线之间的预定算术差异的信号而不是发送剩余的未选择行。