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公开(公告)号：US09685313B2
公开(公告)日：2017-06-20
申请号：US12514972
申请日：2007-11-15
CPC分类号： H01J49/4215 , G01N27/622 , H01J49/004 , H01J49/426
摘要： A mass spectrometer is disclosed comprising an ion mobility spectrometer and an ion gate. A collision cell is arranged downstream of the ion gate. The operation of the ion mobility spectrometer and the ion gate are synchronised so that only ions having a particular mass to charge ratio and a desired charge state are onwardly transmitted to the collision cell.
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公开(公告)号：US09607820B2
公开(公告)日：2017-03-28
申请号：US12306162
申请日：2007-06-25
CPC分类号： H01J49/429 , G01N27/622 , H01J49/0031 , H01J49/004
摘要： A mass spectrometer includes an ion mobility spectrometer or separator arranged upstream of a collision or fragmentation cell. Ions are separated according to their ion mobility within the ion mobility spectrometer or separator. The kinetic energy of the ions exiting the ion mobility spectrometer or separator is increased substantially linearly with time in order to optimize the fragmentation energy of ions as they enter the collision or fragmentation cell. During the time that the potential of the ion mobility spectrometer or separator is being varied, the potential of ion-optical components upstream of the ion mobility spectrometer or separator such as an ion source, ion guide, quadrupole mass filter, optional second collision or fragmentation cell and an ion trapping device are kept constant.
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公开(公告)号：US09466472B2
公开(公告)日：2016-10-11
申请号：US11720520
申请日：2005-12-02
CPC分类号： H01J49/065
摘要： An ion guide is disclosed comprising one or more layers of intermediate planar, plate or mesh electrodes. A first array of first electrodes is provided on a upper surface and a second array of second electrodes is arranged on a lower surface. An ion guiding region is formed within the ion guide. One or more transient DC voltages or potentials are preferably applied to the first and second array of second electrodes in order to urge, propel, force or accelerate ions through or along the ion guide.
摘要翻译： 公开了一种离子导向器，其包括一层或多层中间平面，板或网状电极。 第一电极阵列设置在上表面上，第二电极阵列布置在下表面上。 离子引导区域形成在离子导向器内。 优选地将一个或多个瞬态DC电压或电位施加到第一和第二第二电极阵列，以促进，推进，强迫或加速离子通过或沿着离子导向器。
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公开(公告)号：US09281171B2
公开(公告)日：2016-03-08
申请号：US11721260
申请日：2005-12-08
申请人： Robert Harold Bateman , Kevin Giles , Jeffery Mark Brown , Steven Derek Pringle , Jason Lee Wildgoose
发明人： Robert Harold Bateman , Kevin Giles , Jeffery Mark Brown , Steven Derek Pringle , Jason Lee Wildgoose
CPC分类号： H01J49/062 , H01J49/004
摘要： A mass spectrometer is disclosed comprising a mass selective ion trap or mass analyzer arranged upstream of an ion guide. Ions are scanned out of the mass selective ion trap or mass analyzer and are received in one or more axial potential wells created or formed within the ion guide. One or more transient DC voltages or potentials are preferably applied to the ion guide in order to create a plurality of axial potential wells which are translated along the length of the ion guide. Ions are released in packets from the exit of the ion guide and are orthogonally acceleration into a drift or flight region of an orthogonal acceleration Time of Flight mass analyzer with a relatively high duty cycle.
摘要翻译： 公开了一种质谱仪，其包括布置在离子导向器上游的质量选择性离子阱或质量分析器。 离子从质量选择性离子阱或质量分析器扫描出来，并被接收在一个或多个在离子导向器内产生或形成的轴向势阱中。 优选地将一个或多个瞬态DC电压或电位施加到离子导向器，以便产生沿离子导向件的长度平移的多个轴向势阱。 离子从离子导向器的出口释放出来的离子，并且正交加速到相对较高占空比的正交加速时间飞行质量分析器的漂移或飞行区域。
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公开(公告)号：US09012840B2
公开(公告)日：2015-04-21
申请号：US11720771
申请日：2005-12-07
申请人： Robert Harold Bateman , Kevin Giles
发明人： Robert Harold Bateman , Kevin Giles
CPC分类号： H01J49/0045 , G01N27/622 , H01J49/004 , H01J49/022 , H01J49/062
摘要： A mass spectrometer is disclosed comprising a first quadrupole rod set mass filter, a collision cell, an ion mobility spectrometer or separator, an ion guide or collision cell arranged downstream of the ion mobility spectrometer or separator, a second quadrupole rod set mass filter and an ion detector.
摘要翻译： 公开了一种质谱仪，其包括第一四极杆组质量过滤器，碰撞池，离子迁移谱仪或分离器，设置在离子迁移谱仪或分离器下游的离子导向器或碰撞元件，第二四极杆组质量过滤器和 离子检测器
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公开(公告)号：US06960760B2
公开(公告)日：2005-11-01
申请号：US10829451
申请日：2004-04-22
CPC分类号： H01J49/062
摘要： An ion tunnel ion trap comprises a plurality of electrodes having apertures. The ion tunnel ion trap is preferably coupled to a time of flight mass analyser.
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公开(公告)号：US06891153B2
公开(公告)日：2005-05-10
申请号：US09995662
申请日：2001-11-29
申请人： Robert Harold Bateman , Kevin Giles
发明人： Robert Harold Bateman , Kevin Giles
CPC分类号： H01J49/065
摘要： An ion guide is disclosed comprising a plurality of electrodes each having apertures which are preferably circular and substantially the same size. The ion guide is preferably maintained in a vacuum chamber at a relatively high pressure.
摘要翻译： 公开了一种离子导向器，其包括多个电极，每个电极具有优选为圆形且基本上相同尺寸的孔。 优选将离子导向器保持在较高压力的真空室中。
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公开(公告)号：US06812453B2
公开(公告)日：2004-11-02
申请号：US10178346
申请日：2002-06-25
IPC分类号： H01J4900
CPC分类号： H01J49/062
摘要： An ion guide is disclosed wherein a travelling DC wave is passed along the length of the ion guide so that ions exit the ion guide having substantially the same velocity.
摘要翻译： 公开了一种离子导向器，其中行进的DC波沿着离子导向件的长度通过，使得离子离开离子导向器具有基本上相同的速度。
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公开(公告)号：US06800846B2
公开(公告)日：2004-10-05
申请号：US10448058
申请日：2003-05-30
IPC分类号： H01J4900
CPC分类号： H01J49/0045 , H01J49/065
摘要： A mass spectrometer is disclosed comprising a gas collision cell, reaction cell or collisional cooling cell comprising a plurality of electrodes. DC potentials are progressively applied to the cell so that ions are urged along the cell.
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公开(公告)号：US20100065733A1
公开(公告)日：2010-03-18
申请号：US12306162
申请日：2007-06-25
CPC分类号： H01J49/429 , G01N27/622 , H01J49/0031 , H01J49/004
摘要： A mass spectrometer is disclosed comprising an ion mobility spectrometer or separator (6) arranged upstream of a collision or fragmentation cell (8). Ions are separated according to their ion mobility within the ion mobility spectrometer or separator (6). The kinetic energy of the ions exiting the ion mobility spectrometer or separator (6) is increased substantially linearly with time in order to optimise the fragmentation energy of ions as they enter the collision or fragmentation cell (8). During the time that the potential of the ion mobility spectrometer or separator (6) is being varied, the potential of ion-optical components upstream of the ion mobility spectrometer or separator (6) such as an ion source (1), ion guide (2), quadrupole mass filter (3), optional second collision or fragmentation cell (4) and an ion trapping device (5) are kept constant.
摘要翻译： 公开了一种质谱仪，其包括设置在碰撞或分裂单元（8）的上游的离子迁移谱仪或分离器（6）。 根据离子迁移谱仪或分离器（6）内的离子迁移率分离离子。 离子离子迁移谱仪或分离器（6）离子的动能随着时间的推移基本线性地增加，以优化离子进入碰撞或破碎电池（8）时的碎裂能。 在离子迁移谱仪或分离器（6）的电位变化的时间内，离子迁移谱仪或分离器（6）上游离子光学部件的离子源（1），离子导向器 2），四极质量过滤器（3），任选的第二碰撞或碎裂单元（4）和离子捕获装置（5）保持恒定。
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