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公开(公告)号:US20190221414A1
公开(公告)日:2019-07-18
申请号:US16363219
申请日:2019-03-25
CPC分类号: H01J49/065 , H01J49/0027 , H01J49/022 , H01J49/424
摘要: A miniature electrode apparatus is disclosed for trapping charged particles, the apparatus includes, along a longitudinal direction, a first end cap electrode, a central electrode having an aperture, and a second end cap electrode. The aperture is elongated in the lateral plane and extends through the central electrode along the longitudinal direction and the central electrode surrounds the aperture in a lateral plane perpendicular to the longitudinal direction to define a transverse cavity for trapping charged particles. Electric fields can be applied in a y-direction of the lateral plane across one or more planes perpendicular to the longitudinal axis to translocate and/or manipulate ion trajectories.
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公开(公告)号:US20190157058A1
公开(公告)日:2019-05-23
申请号:US16315883
申请日:2016-08-22
申请人: SHIMADZU CORPORATION
发明人: Shiro MIZUTANI
CPC分类号: H01J49/022 , H01J49/40 , H01J49/403
摘要: An acceleration voltage generator generates a high-voltage pulse applied to a push-out electrode, by operating a switch section to turn on and off a high direct-current voltage generated by a high-voltage power supply. A drive pulse signal is supplied from a controller to the switch section through a primary-side drive section, transformer, and secondary-side drive section. A primary-voltage controller receives a measurement result of ambient temperature of the acceleration voltage generator from a temperature sensor, and controls a primary-side power supply to change a primary-side voltage according to the temperature, thereby adjusting the voltage applied between the two ends of a primary winding of the transformer. The adjustment made on the primary-side voltage changes a slope angle of rise of a gate voltage in the MOSFET, and enables a correction to a discrepancy in the timing of the rise/fall of the high-voltage pulse caused by change in ambient temperature.
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公开(公告)号:US20190080892A1
公开(公告)日:2019-03-14
申请号:US16150624
申请日:2018-10-03
申请人: Micromass UK Limited
CPC分类号: H01J49/0036 , H01J49/0031 , H01J49/022 , H01J49/4215 , H01J49/422 , H01J49/4275
摘要: A voltage supply system for supplying an RF voltage to an RF resonant load comprising an ion-optical component of a mass spectrometer is disclosed. The system comprises a Direct Digital Synthesiser (“DDS”) arranged and adapted to output an RF voltage. The voltage supply system is arranged and adapted: (i) to vary the frequency of the RF voltage output by the Direct Digital Synthesiser, (ii) to determine a first resonant frequency of the RF resonant load comprising the ion-optical component, and (iii) to determine whether or not the generation of an RF voltage at the first resonant frequency by the Direct Digital Synthesiser would also result in the generation of a spur frequency close to the first resonant frequency. If it is determined that a spur frequency would be generated close to the first resonant frequency then the voltage supply system is further arranged and adapted: (iv) to consult a look-up table comprising one or more preferred frequencies, and (v) to direct the Direct Digital Synthesiser to generate an RF voltage at a second frequency which corresponds with one of the preferred frequencies from the look-up table, wherein the second frequency is different to said first resonant frequency.
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公开(公告)号:US20180247803A1
公开(公告)日:2018-08-30
申请号:US15903728
申请日:2018-02-23
申请人: 908 Devices Inc.
发明人: Christopher D. Brown , Evgeny Krylov , Michael Goodwin , Kerin Gregory , Andrew J. Bartfay-Szabo
CPC分类号: H01J49/0095 , H01J49/0036 , H01J49/022 , H01J49/025 , H01J49/427
摘要: The disclosure features mass spectrometry systems and methods that include an ion source, an ion trap, a detector subsystem featuring first and second detector elements, and a controller electrically connected to the ion source, the ion trap, and the detector subsystem and configured so that during operation of the system, the controller: applies an electrical signal to the ion source to generate positively and negatively charged particles from sample particles in the system; applies an electrical signal to the ion trap to eject a plurality of particles from the ion trap through a common aperture of the ion trap, and determines information about the sample particles based on first and second electrical signals generated by the ejected particles.
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公开(公告)号:US09991106B2
公开(公告)日:2018-06-05
申请号:US15248401
申请日:2016-08-26
申请人: Micromass UK Limited
CPC分类号: H01J49/0036 , G01N27/622 , H01J49/0009 , H01J49/022 , H01J49/40
摘要: A method is disclosed comprising passing a signal output from a detector through a programmable attenuator or a programmable amplifier prior to digitizing the signal, and switching an attenuation factor or gain factor of the programmable attenuator or the programmable amplifier one or more times during a data acquisition period.
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公开(公告)号:US09953815B2
公开(公告)日:2018-04-24
申请号:US15621259
申请日:2017-06-13
申请人: Elmer Griebeler
发明人: Elmer Griebeler
CPC分类号: H01J49/022 , H01F27/34 , H01F27/40 , H01F2027/408 , H02M7/539 , H03K3/02 , H03K3/57
摘要: A high-voltage waveform generator comprising a power source, a transformer unit comprising a magnetic core, attached to the power source, a plurality of power switch cards, each having an aperture that allows said magnetic core to pass therethrough, one or more control switches located on each power card, and a control means for actuating the control switches, a power output; wherein the power switch cards are connected in series, wherein each of the apertures in the power switch cards is surrounded by conductive windings, whereby when the power source is activated, the magnetic core induces a current in each of the conductive windings, and wherein the control means activates the control switches simultaneously in under 100 nanoseconds to generate a pulse.
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公开(公告)号:US09927396B2
公开(公告)日:2018-03-27
申请号:US14354489
申请日:2012-10-26
发明人: Brian D. Peterson , Dale Alan Owens , Peter S. Kotowski , Sunil S. Deliwala , Craig A. Hudson , James H. Reyes , Clive Cheung , Tom Tran , Anna X. Lou , Jane Luo , Jean-Marc Rene Lucien Busnel , Chitra K. Ratnayake
IPC分类号: G01N27/447 , G01N30/72 , H01J49/02 , H01J49/16
CPC分类号: G01N27/44743 , G01N27/44717 , G01N30/7266 , H01J49/022 , H01J49/165 , Y10T307/313
摘要: Aspects of the innovations presented herein relate to improved systems that in some embodiments perform capillary electrophoresis (CE) and CE in conjunction with electrospray ionization (ESI) as an input to a mass spectrometry system (MS). Some embodiments use a high voltage isolated CE power supply that is configured to float on the high voltage output of an ESI-MS power supply, with a protective resistance in the ESI-MS path, as well as DC/DC converter isolation and communication system isolation for the isolated CE power supply. Some embodiments additionally use a cartridge assembly integrating separation and conductive fluid capillaries with fluid cooling and protective retractable housings for the capillary end portions and for the ESI output. The protective housing may further be used with an adapter for interfacing with different MS systems.
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公开(公告)号:US20180082829A1
公开(公告)日:2018-03-22
申请号:US15503342
申请日:2016-01-21
发明人: Takayuki MURO , Tomohiro MATSUSHITA
CPC分类号: H01J49/488 , H01J37/05 , H01J37/244 , H01J49/022 , H01J2237/053 , H01J2237/057 , H01J2237/24485
摘要: A retarding potential type energy analyzer including a front grid electrode, reference grid electrode and rear grid electrode sequentially arranged, with a predetermined amount of potential difference given between the reference grid electrode and the front grid electrode to form an upward potential gradient as well as a potential difference given between the reference grid electrode and the rear grid electrode to form a downward potential gradient, the grid electrodes are arranged so that the distance between the reference grid electrode and the rear grid electrode is shorter than the distance between the reference grid electrode and the front grid electrode, or the potential difference between the reference grid electrode and the rear grid electrode is made to be greater than the potential difference between the reference grid electrode and the front grid electrode.
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公开(公告)号:US20170316928A1
公开(公告)日:2017-11-02
申请号:US15645147
申请日:2017-07-10
申请人: Ian W. HUNTER , Brian D. HEMOND , Harold F. HEMOND
发明人: Ian W. HUNTER , Brian D. HEMOND , Harold F. HEMOND
CPC分类号: H01J49/30 , H01J49/0013 , H01J49/0031 , H01J49/022 , H01J49/147 , H01J49/24
摘要: A miniature, low cost mass spectrometer capable of unit resolution over a mass range of 10 to 50 AMU. The mass spectrometer incorporates several features that enhance the performance of the design over comparable instruments. An efficient ion source enables relatively low power consumption without sacrificing measurement resolution. Variable geometry mechanical filters allow for variable resolution. An onboard ion pump removes the need for an external pumping source. A magnet and magnetic yoke produce magnetic field regions with different flux densities to run the ion pump and a magnetic sector mass analyzer. An onboard digital controller and power conversion circuit inside the vacuum chamber allows a large degree of flexibility over the operation of the mass spectrometer while eliminating the need for high-voltage electrical feedthroughs. The miniature mass spectrometer senses fractions of a percentage of inlet gas and returns mass spectra data to a computer.
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公开(公告)号:US20170062197A1
公开(公告)日:2017-03-02
申请号:US15248401
申请日:2016-08-26
申请人: Micromass UK Limited
CPC分类号: H01J49/0036 , G01N27/622 , H01J49/0009 , H01J49/022 , H01J49/40
摘要: A method is disclosed comprising passing a signal output from a detector through a programmable attenuator or a programmable amplifier prior to digitising the signal, and switching an attenuation factor or gain factor of the programmable attenuator or the programmable amplifier one or more times during a data acquisition period.
摘要翻译: 公开了一种方法,包括在数字化信号之前将来自检测器的信号输出通过可编程衰减器或可编程放大器,以及在数据采集期间切换可编程衰减器或可编程放大器的衰减因子或增益因子一次或多次 期。
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