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    Guidewire with superelastic distal portion
    1.
    发明授权
    Guidewire with superelastic distal portion 失效
    导丝与超弹性远端部分

    公开(公告)号：US5341818A

    公开(公告)日：1994-08-30

    申请号：US994679

    申请日：1992-12-22

    申请人： Robert M. Abrams ,  Randy S. Chan ,  Janet W. Burpee ,  Clifford Teoh

    发明人： Robert M. Abrams ,  Randy S. Chan ,  Janet W. Burpee ,  Clifford Teoh

    IPC分类号： A61L31/02 ,  A61M25/09 ,  C22C14/00 ,  C22C30/00 ,  C22F1/00 ,  A61B5/00

    CPC分类号： A61L31/14 ,  A61L31/022 ,  A61M25/09 ,  C22C14/00 ,  C22C30/00 ,  C22F1/006 ,  A61L2400/16 ,  A61M2025/09083 ,  A61M2025/09141 ,  A61M2025/09175 ,  A61M2205/0266

    摘要： An improved guidewire for advancing a catheter within a body lumen which has a high strength proximal portion, a distal portion formed of superelastic alloy and a connector formed of superelastic alloy to provide a torque transmitting coupling between the distal end of the proximal portion and the proximal end of the distal portion. The superelastic alloy elements are preferably cold worked and then heat treated at a temperature well above the austenite-to-martensite transformation temperature, while being subjected to longitudinal stresses equal to about 5 to about 50% of the room temperature yield stress to impart to the metal a straight "memory". The guiding member using such improved material exhibits a stress induced austenite-to-martensite phase transformation at an exceptionally high constant yield strength of at least 70 ksi for solid members and at least 50 ksi for tubular members with a broad recoverable strain of at least about 4% during the phase transformation.

    摘要翻译： 一种改进的导丝，用于将导管推进在具有高强度近端部分的体腔内，由超弹性合金形成的远端部分和由超弹性合金形成的连接器，以在近端部分的远端和近端部分之间提供扭矩传递联接 远端部分的末端。 超弹性合金元素优选是冷加工的，然后在远高于奥氏体 - 马氏体转变温度的温度下进行热处理，同时经受等于室温屈服应力的约5至约50％的纵向应力，以赋予 金属直“记忆”。 使用这种改进的材料的引导构件在固体构件具有至少70ksi的异常高的恒定屈服强度和至少50ksi的管状构件的情况下表现出应力诱导的奥氏体 - 马氏体相变，其具有至少大约的可恢复应变 在相变期间为4％。

    Method of soldering Ti containing alloys
    2.
    发明授权
    Method of soldering Ti containing alloys 失效
    焊接含Ti合金的方法

    公开(公告)号：US06602228B2

    公开(公告)日：2003-08-05

    申请号：US10021528

    申请日：2001-12-10

    申请人： Leonard Nanis ,  Robert M. Abrams ,  Randy S. Chan ,  Janet Walsh Burpee ,  Clifford Teoh

    发明人： Leonard Nanis ,  Robert M. Abrams ,  Randy S. Chan ,  Janet Walsh Burpee ,  Clifford Teoh

    IPC分类号： A61M5178

    CPC分类号： A61L31/14 ,  A61L31/022 ,  A61L2400/16 ,  A61M25/09 ,  A61M2025/09083 ,  A61M2025/09141 ,  A61M2025/09175 ,  A61M2205/0266 ,  C22C14/00 ,  C22C30/00 ,  C22F1/006

    摘要： An improved guidewire for advancing a catheter within a body lumen which has a high strength proximal portion, a distal portion formed of superelastic alloy and a connector formed of superelastic alloy to provide torque transmitting coupling between the distal end of the proximal portion and the proximal end of the distal portion. The superelastic alloy elements are preferably cold worked and then heat treated at a temperature well above the austenite-to-martensite transformation temperature, while being subjected to longitudinal stresses equal to about 5 to about 50% of the room temperature yield stress to impart to the metal a straight “memory.” The guiding member using such improved material exhibits a stress induced austenite-to-martensite phase transformation at an exceptionally high constant yield strength of at least 70 ksi for solid members and at least 50 ksi for tubular members with a broad recoverable strain of at least about 4% during the phase transformation.

    摘要翻译： 一种用于将导管推进在具有高强度近端部分的体腔内的改进的导丝，由超弹性合金形成的远端部分和由超弹性合金形成的连接器，以在近端部分的远端和近端之间提供扭矩传递联接 的远端部分。 超弹性合金元素优选是冷加工的，然后在远高于奥氏体 - 马氏体转变温度的温度下进行热处理，同时经受等于室温屈服应力的约5至约50％的纵向应力，以赋予 金属直“记忆”。 使用这种改进的材料的引导构件在固体构件具有至少70ksi的异常高的恒定屈服强度和至少50ksi的管状构件的情况下表现出应力诱导的奥氏体 - 马氏体相变，其具有至少大约的可恢复应变 在相变期间为4％。

    Intracorporeal device with NiTi tubular member
    3.
    发明授权
    Intracorporeal device with NiTi tubular member 失效
    具有NiTi管状构件的体内装置

    公开(公告)号：US06379369B1

    公开(公告)日：2002-04-30

    申请号：US08982725

    申请日：1997-12-02

    申请人： Robert M. Abrams ,  Randy S. Chan ,  Janet Walsh Burpee ,  Clifford Teoh

    发明人： Robert M. Abrams ,  Randy S. Chan ,  Janet Walsh Burpee ,  Clifford Teoh

    IPC分类号： A61M2500

    CPC分类号： A61M25/09 ,  A61L31/022 ,  A61L31/14 ,  A61L2400/16 ,  A61M2025/09008 ,  A61M2025/09083 ,  A61M2025/09141 ,  A61M2025/09175 ,  A61M2205/0266 ,  C22C14/00 ,  C22C30/00 ,  C22F1/006

    摘要： An improved guidewire for advancing a catheter within a body lumen which has a high strength proximal portion, a distal portion formed of superelastic alloy and a connector formed of superelastic alloy to provide torque transmitting coupling between the distal end of the proximal portion and the proximal end of the distal portion. The superelastic alloy elements are preferably cold worked and then heat treated at a temperature well above the austenite-to-martensite transformation temperature, while being subjected to longitudinal stresses equal to about 5 to about 50% of the room temperature yield stress to impart to the metal a straight “memory.” The guiding member using such improved material exhibits a stress induced austenite-to-martensite phase transformation at an exceptionally high constant yield strength of at least 70 ksi for solid members and at least 50 ksi for tubular members with a broad recoverable strain of at least about 4% during the phase transformation.

    摘要翻译： 一种用于将导管推进在具有高强度近端部分的体腔内的改进的导丝，由超弹性合金形成的远端部分和由超弹性合金形成的连接器，以在近端部分的远端和近端之间提供扭矩传递联接 的远端部分。 超弹性合金元素优选是冷加工的，然后在远高于奥氏体 - 马氏体转变温度的温度下进行热处理，同时经受等于室温屈服应力的约5至约50％的纵向应力，以赋予 金属直“记忆”。 使用这种改进的材料的引导构件在固体构件具有至少70ksi的异常高的恒定屈服强度和至少50ksi的管状构件的情况下表现出应力诱导的奥氏体 - 马氏体相变，其具有至少大约的可恢复应变 在相变期间为4％。

    Method of soldering TI containing alloys
    4.
    发明授权
    Method of soldering TI containing alloys 失效
    焊接含TI合金的方法

    公开(公告)号：US5695111A

    公开(公告)日：1997-12-09

    申请号：US276082

    申请日：1994-07-15

    申请人： Leonard Nanis ,  Robert M. Abrams ,  Randy S. Chan ,  Janet Walsh Burpee ,  Clifford Teoh

    发明人： Leonard Nanis ,  Robert M. Abrams ,  Randy S. Chan ,  Janet Walsh Burpee ,  Clifford Teoh

    IPC分类号： A61L31/02 ,  A61M25/09 ,  C22C14/00 ,  C22C30/00 ,  C22F1/00 ,  B23K103/14 ,  B23K31/02

    CPC分类号： A61L31/14 ,  A61L31/022 ,  A61M25/09 ,  C22C14/00 ,  C22C30/00 ,  C22F1/006 ,  A61L2400/16 ,  A61M2025/09083 ,  A61M2025/09141 ,  A61M2025/09175 ,  A61M2205/0266

    摘要： An improved guidewire for advancing a catheter within a body lumen which has a high strength proximal portion, a distal portion formed of superelastic alloy and a connector formed of superelastic alloy to provide torque transmitting coupling between the distal end of the proximal portion and the proximal end of the distal portion. The superelastic alloy elements are preferably cold worked and then heat treated at a temperature well above the austenite-to-martensite transformation temperature, while being subjected to longitudinal stresses equal to about 5 to about 50% of the room temperature yield stress to impart to the metal a straight "memory." The guiding member using such improved material exhibits a stress induced austenite-to-martensite phase transformation at an exceptionally high constant yield strength of at least 70 ksi for solid members and at least 50 ksi for tubular members with a broad recoverable strain of at least about 4% during the phase transformation.

    摘要翻译： 一种用于将导管推进在具有高强度近端部分的体腔内的改进的导丝，由超弹性合金形成的远端部分和由超弹性合金形成的连接器，以在近端部分的远端和近端之间提供扭矩传递联接 的远端部分。 超弹性合金元素优选是冷加工的，然后在远高于奥氏体 - 马氏体转变温度的温度下进行热处理，同时经受等于室温屈服应力的约5至约50％的纵向应力，以赋予 金属直“记忆”。 使用这种改进的材料的引导构件在固体构件具有至少70ksi的异常高的恒定屈服强度和至少50ksi的管状构件的情况下表现出应力诱导的奥氏体 - 马氏体相变，其具有至少大约的可恢复应变 在相变期间为4％。

    Detachable, varying flexibility, aneurysm neck bridge
    7.
    发明授权
    Detachable, varying flexibility, aneurysm neck bridge 有权
    可分离，灵活性差，动脉瘤颈桥

    公开(公告)号：US06063104A

    公开(公告)日：2000-05-16

    申请号：US313958

    申请日：1999-05-18

    申请人： Francisco S. Villar ,  Nestor Aganon ,  Nga T. Doan ,  Robert M. Abrams ,  Clifford Teoh

    发明人： Francisco S. Villar ,  Nestor Aganon ,  Nga T. Doan ,  Robert M. Abrams ,  Clifford Teoh

    IPC分类号： A61B17/03 ,  A61B17/12

    CPC分类号： A61B17/12022 ,  A61B17/12113 ,  A61B17/1214 ,  A61B17/12172 ,  A61B2017/12063

    摘要： This is a device for bridging the neck of either a wide-necked or narrow-necked aneurysm as may be found in the vasculature. It may be used to stabilize the placement of vaso-occlusive devices such as helically wound coils in the aneurysm or may be used to, at least partially, close the aneurysm neck. The vaso-occlusive devices, commonly helically wound coils, are delivered by a core wire which is linked to the coils by an electrolytically severable joint. The core wire will often be insulated. The retainer assembly itself is also attached to another delivery device, such as a core wire, and desirably is severed from the core or delivery wire by the use of another electrolytically severable joint. The inventive neck bridge typically has a number of array elements which are intended to be resident within the aneurysm after the device is deployed from the distal end of a catheter. Central to this invention is the use of array elements having differing flexibility or constituent members of the array elements, e.g., wires making up the array elements, which are of differing flexibilities. After deployment of this retainer, the aneurysm may be at least partially filled with vaso-occlusive devices such as helically wound coils.

    摘要翻译： 这是用于桥接可能在脉管系统中发现的宽颈或窄颈动脉瘤的颈部的装置。 其可以用于稳定血管闭塞装置的放置，例如螺旋缠绕的线圈在动脉瘤中，或者可以用于至少部分地闭合动脉瘤颈部。 通常为螺旋缠绕线圈的血管收缩装置由通过电解分离的关节连接到线圈的芯线递送。 芯线通常是绝缘的。 保持器组件本身也附接到另一个输送装置，例如芯线，并且期望地通过使用另一个可电解的接头与芯或输送线断开。 本发明的颈桥通常具有许多阵列元件，其在从导管的远端部署装置之后意图驻留在动脉瘤内。 本发明的中心是使用具有不同柔性的阵列元件或阵列元件的构成元件，例如构成阵列元件的线，其具有不同的灵活性。 在部署该保持器之后，动脉瘤可以至少部分地被血管闭塞装置填充，例如螺旋卷绕的线圈。

    Detachable, varying flexibility, aneurysm neck bridge
    8.
    发明授权
    Detachable, varying flexibility, aneurysm neck bridge 失效

    公开(公告)号：US5935148A

    公开(公告)日：1999-08-10

    申请号：US103472

    申请日：1998-06-24

    申请人： Francisco S. Villar ,  Nestor Aganon ,  Nga T. Doan ,  Robert M. Abrams ,  Clifford Teoh

    发明人： Francisco S. Villar ,  Nestor Aganon ,  Nga T. Doan ,  Robert M. Abrams ,  Clifford Teoh

    IPC分类号： A61B17/03 ,  A61B17/12

    CPC分类号： A61B17/12022 ,  A61B17/12113 ,  A61B17/1214 ,  A61B17/12172 ,  A61B2017/12063

    摘要： This is a device for bridging the neck of either a wide-necked or narrow-necked aneurysm as may be found in the vasculature. It may be used to stabilize the placement of vaso-occlusive devices such as helically wound coils in the aneurysm or may be used to, at least partially, close the aneurysm neck. The vaso-occlusive devices, commonly helically wound coils, are delivered by a core wire which is linked to the coils by an electrolytically severable joint. The core wire will often be insulated. The retainer assembly itself is also attached to another delivery device, such as a core wire, and desirably is severed from the core or delivery wire by the use of another electrolytically severable joint. The inventive neck bridge typically has a number of array elements which are intended to be resident within the aneurysm after the device is deployed from the distal end of a catheter. Central to this invention is the use of array elements having differing flexibility or constituent members of the array elements, e.g., wires making up the array elements, which are of differing flexibilities. After deployment of this retainer, the aneurysm may be at least partially filled with vaso-occlusive devices such as helically wound coils.