公开(公告)号：US20090247792A1

公开(公告)日：2009-10-01

申请号：US12390608

申请日：2009-02-23

申请人： Robert P. Jansen ,  Anthony Baiada ,  John Kerr

发明人： Robert P. Jansen ,  Anthony Baiada ,  John Kerr

IPC分类号： C07C31/22

CPC分类号： C07C29/86 ,  C07C31/225

摘要： A process for the recovery of glycerol comprises contacting an aqueous feed composition that comprises water, glycerol, and at least one contaminant with a solvent extractant comprising at least one C5-C8 alkanol, optionally in admixture with at least one alkane, to form a first mixture, and separating the first mixture into a first solvent phase and a first aqueous phase. The first solvent phase comprises a majority (more than 50 wt %) of the solvent extractant and a majority of the glycerol that was present in the aqueous feed composition. The weight ratio in the first solvent phase of glycerol to a contaminant present is greater than the weight ratio of glycerol to the contaminant in the aqueous feed composition. The first aqueous phase comprises a majority of the water from the aqueous feed composition and at least some of the contaminant from the aqueous feed composition.

摘要翻译： 用于回收甘油的方法包括使包含水，甘油和至少一种污染物的含水进料组合物与包含至少一种C5-C8链烷醇的溶剂萃取剂接触，任选与至少一种烷烃混合形成第一 混合物，并将第一混合物分离成第一溶剂相和第一水相。 第一溶剂相包含大部分（超过50重量％）的溶剂萃取剂和存在于含水进料组合物中的大部分甘油。 丙三醇与污染物的第一溶剂相中的重量比大于水性进料组合物中甘油与污染物的重量比。 第一水相包含来自含水进料组合物的大部分水和来自含水进料组合物的至少一些污染物。

公开(公告)号：US08084651B2

公开(公告)日：2011-12-27

申请号：US12390608

申请日：2009-02-23

申请人： Robert P. Jansen ,  Anthony Baiada ,  John Kerr

发明人： Robert P. Jansen ,  Anthony Baiada ,  John Kerr

IPC分类号： C07C31/22

CPC分类号： C07C29/86 ,  C07C31/225

摘要： A process for the recovery of glycerol comprises contacting an aqueous feed composition that comprises water, glycerol, and at least one contaminant with a solvent extractant comprising at least one C5-C8 alkanol, optionally in admixture with at least one alkane, to form a first mixture, and separating the first mixture into a first solvent phase and a first aqueous phase. The first solvent phase comprises a majority (more than 50 wt %) of the solvent extractant and a majority of the glycerol that was present in the aqueous feed composition. The weight ratio in the first solvent phase of glycerol to a contaminant present is greater than the weight ratio of glycerol to the contaminant in the aqueous feed composition. The first aqueous phase comprises a majority of the water from the aqueous feed composition and at least some of the contaminant from the aqueous feed composition.

摘要翻译： 用于回收甘油的方法包括使包含水，甘油和至少一种污染物的含水进料组合物与包含至少一种C5-C8链烷醇的溶剂萃取剂接触，任选与至少一种烷烃混合形成第一 混合物，并将第一混合物分离成第一溶剂相和第一水相。 第一溶剂相包含大部分（超过50重量％）的溶剂萃取剂和存在于含水进料组合物中的大部分甘油。 丙三醇与污染物的第一溶剂相中的重量比大于水性进料组合物中甘油与污染物的重量比。 第一水相包含来自含水进料组合物的大部分水和来自含水进料组合物的至少一些污染物。

公开(公告)号：US07572376B2

公开(公告)日：2009-08-11

申请号：US11352593

申请日：2006-02-13

申请人： Avraham M. Baniel ,  Robert P. Jansen ,  Asher Vitner ,  Anthony Baiada

发明人： Avraham M. Baniel ,  Robert P. Jansen ,  Asher Vitner ,  Anthony Baiada

IPC分类号： B01D11/00 ,  C07C31/18

CPC分类号： C07C29/86 ,  B01D11/0446 ,  B01D11/0488 ,  B01D11/0492 ,  C02F1/26 ,  C07C31/205

摘要： Disclosed herein are processes for the recovery of 1,3-propanediol from an aqueous feed stream. The present invention involves contacting an aqueous feed stream that comprises water, 1,3-propanediol, and at least one contaminant with at least one solvent extractant to form a mixture. The mixture is separated into a first phase and a second phase. The second phase comprises a majority of the water from the aqueous feed stream. The first phase comprises solvent extractant and at least some of the 1,3-propanediol that was present in the aqueous feed stream. The weight ratio in the first phase of 1,3-propanediol to any one contaminant present is greater than the weight ratio of 1,3-propanediol to the same contaminant in the aqueous feed stream prior to the aqueous feed stream being contacted with the solvent extractant. The first phase can be removed from the separated second phase in order to recover the 1,3-propanediol.

摘要翻译： 本文公开了从含水原料流中回收1,3-丙二醇的方法。 本发明涉及将包含水，1,3-丙二醇和至少一种污染物的含水进料流与至少一种溶剂萃取剂接触以形成混合物。 将混合物分离成第一相和第二相。 第二相包含来自含水进料流的大部分水。 第一阶段包括溶剂萃取剂和存在于含水进料流中的至少一些1,3-丙二醇。 在水性进料流与溶剂接触之前，1,3-丙二醇与任何一种污染物的第一相中的重量比大于1,3-丙二醇与含水进料流中相同污染物的重量比 萃取剂。 为了回收1,3-丙二醇，可以将第一相从分离的第二相中除去。

公开(公告)号：US07056439B2

公开(公告)日：2006-06-06

申请号：US10430498

申请日：2003-05-06

申请人： Avraham M. Baniel ,  Robert P. Jansen ,  Asher Vitner ,  Anthony Baiada

发明人： Avraham M. Baniel ,  Robert P. Jansen ,  Asher Vitner ,  Anthony Baiada

IPC分类号： B01D11/00 ,  C07C7/10

CPC分类号： C07C29/86 ,  B01D11/0446 ,  B01D11/0488 ,  B01D11/0492 ,  C02F1/26 ,  C07C31/205

摘要： Disclosed herein are processes for the recovery of 1,3-propanediol from an aqueous feed stream. The present invention involves contacting an aqueous feed stream that comprises water, 1,3-propanediol, and at least one contaminant with at least one solvent extractant to form a mixture. The mixture is separated into a first phase and a second phase. The second phase comprises a majority of the water from the aqueous feed stream. The first phase comprises solvent extractant and at least some of the 1,3-propanediol that was present in the aqueous feed stream. The weight ratio in the first phase of 1,3-propanediol to any one contaminant present is greater than the weight ratio of 1,3-propanediol to the same contaminant in the aqueous feed stream prior to the aqueous feed stream being contacted with the solvent extractant. The first phase can be removed from the separated second phase in order to recover the 1,3-propanediol.

摘要翻译： 本文公开了从含水原料流中回收1,3-丙二醇的方法。 本发明涉及将包含水，1,3-丙二醇和至少一种污染物的含水进料流与至少一种溶剂萃取剂接触以形成混合物。 将混合物分离成第一相和第二相。 第二相包含来自含水进料流的大部分水。 第一阶段包括溶剂萃取剂和存在于含水进料流中的至少一些1,3-丙二醇。 在水性进料流与溶剂接触之前，1,3-丙二醇与任何一种污染物的第一相中的重量比大于1,3-丙二醇与含水进料流中相同污染物的重量比 萃取剂。 为了回收1,3-丙二醇，可以将第一相从分离的第二相中除去。

公开(公告)号：US08404109B2

公开(公告)日：2013-03-26

申请号：US13316278

申请日：2011-12-09

申请人： Robert Jansen ,  John Kerr ,  Anthony Baiada

发明人： Robert Jansen ,  John Kerr ,  Anthony Baiada

IPC分类号： B01D17/12 ,  C13K3/00 ,  B01J14/00

CPC分类号： C13K3/00 ,  C13B20/14

摘要： A method of inverting sucrose, including (i) determining an initial solids concentration of an aqueous sucrose solution, an initial bed volume of a sucrose inversion resin system, a minimum target inversion percentage, a maximum target inversion percentage, a target maximum hydroxymethylfuran (HMF) concentration, a minimum target pH, or a maximum target pH; (ii) contacting the sucrose inversion resin system with the aqueous sucrose solution under conditions of aqueous solution flow rate and aqueous solution temperature to produce an inverted sucrose solution having an inversion percentage, an HMF concentration, and a pH; (iii) observing an instantaneous inversion percentage, an instantaneous HMF concentration, or an instantaneous pH of the inverted sucrose solution; and, if appropriate; (iv) changing at least one of the aqueous solution flow rate or the aqueous solution temperature to yield a product having a desired inversion percentage, HMF concentration, and/or pH. An apparatus capable of performing the method.

摘要翻译： 一种反相蔗糖的方法，包括（i）测定蔗糖水溶液的初始固体浓度，蔗糖反转树脂体系的初始床体积，最小目标反转百分比，最大目标反转百分比，目标最大羟甲基呋喃（HMF ）浓度，最小目标pH或最大目标pH; （ii）在水溶液流动速率和水溶液温度条件下使蔗糖反转树脂体系与蔗糖溶液水溶液接触，以产生具有倒置百分比，HMF浓度和pH值的倒置蔗糖溶液; （iii）观察反转蔗糖溶液的瞬时反转百分比，瞬时HMF浓度或瞬时pH值; 并酌情; （iv）改变水溶液流速或水溶液温度中的至少一个，得到具有所需转化百分比，HMF浓度和/或pH值的产物。 一种能够执行该方法的装置。

公开(公告)号：US20090264633A1

公开(公告)日：2009-10-22

申请号：US12345998

申请日：2008-12-30

申请人： John Kerr ,  Robert Jansen ,  Duane A. Leinhos ,  James Edwin Wiley, JR. ,  Sebastien Camborieux ,  Anthony Baiada ,  Gordon Walker ,  Carlo Maffezzoni

发明人： John Kerr ,  Robert Jansen ,  Duane A. Leinhos ,  James Edwin Wiley, JR. ,  Sebastien Camborieux ,  Anthony Baiada ,  Gordon Walker ,  Carlo Maffezzoni

IPC分类号： C07H15/00

CPC分类号： C07H1/06 ,  C07H5/02

摘要： The present invention provides a method for producing sucralose from a feed stream resulting from the chlorination of a sucrose-6-acylate in a reaction vehicle. The feed stream includes a sucralose-6-acylate, the reaction vehicle, water, and salts. The salts include one or more selected from the group consisting of alkali metal chlorides, alkaline earth metal chlorides and ammonium chloride. The method includes: (i) deacylation of the sucralose-6-acylate by treatment with a base to afford a product stream comprising sucralose; (ii) partial removal of water and, optionally, reaction vehicle from the product stream of (i) in order to cause precipitation of the salts from the product stream; (iii) removal of the precipitated salts from the product stream of (ii); and (iv) isolation of sucralose from the product stream of (iii).

摘要翻译： 本发明提供了由反应载体中蔗糖-6-酰化物的氯化得到的进料流中生产三氯蔗糖的方法。 进料流包括三氯蔗糖-6-酰化物，反应载体，水和盐。 所述盐包括选自碱金属氯化物，碱土金属氯化物和氯化铵中的一种或多种。 该方法包括：（i）用碱处理三氯半乳蔗糖-6-酰化物脱酰基，得到包含三氯蔗糖的产物流; （ii）从（i）的产物流中部分除去水和任选的反应载体，以便使产物流中的盐沉淀; （iii）从（ii）的产物流中除去沉淀的盐; 和（iv）从（iii）的产物流中分离三氯半乳蔗糖。

公开(公告)号：US08436156B2

公开(公告)日：2013-05-07

申请号：US12345998

申请日：2008-12-30

申请人： John Kerr ,  Robert Jansen ,  Duane A. Leinhos ,  James Edwin Wiley, Jr. ,  Sebastien Camborieux ,  Anthony Baiada ,  Gordon Walker ,  Carlo Maffezzoni

发明人： John Kerr ,  Robert Jansen ,  Duane A. Leinhos ,  James Edwin Wiley, Jr. ,  Sebastien Camborieux ,  Anthony Baiada ,  Gordon Walker ,  Carlo Maffezzoni

IPC分类号： C07H15/00

CPC分类号： C07H1/06 ,  C07H5/02

摘要： The present invention provides a method for producing sucralose from a feed stream resulting from the chlorination of a sucrose-6-acylate in a reaction vehicle. The feed stream includes a sucralose-6-acylate, the reaction vehicle, water, and salts. The salts include one or more selected from the group consisting of alkali metal chlorides, alkaline earth metal chlorides and ammonium chloride. The method includes: (i) deacylation of the sucralose-6-acylate by treatment with a base to afford a product stream comprising sucralose; (ii) partial removal of water and, optionally, reaction vehicle from the product stream of (i) in order to cause precipitation of the salts from the product stream; (iii) removal of the precipitated salts from the product stream of (ii); and (iv) isolation of sucralose from the product stream of (iii).

摘要翻译： 本发明提供了由反应载体中蔗糖-6-酰化物的氯化得到的进料流中生产三氯蔗糖的方法。 进料流包括三氯蔗糖-6-酰化物，反应载体，水和盐。 所述盐包括选自碱金属氯化物，碱土金属氯化物和氯化铵中的一种或多种。 该方法包括：（i）用碱处理三氯半乳蔗糖-6-酰化物脱酰基，得到包含三氯蔗糖的产物流; （ii）从（i）的产物流中部分除去水和任选的反应载体，以便使产物流中的盐沉淀; （iii）从（ii）的产物流中除去沉淀的盐; 和（iv）从（iii）的产物流中分离三氯半乳蔗糖。

公开(公告)号：US08092609B2

公开(公告)日：2012-01-10

申请号：US12025153

申请日：2008-02-04

申请人： Robert Jansen ,  John Kerr ,  Anthony Baiada

发明人： Robert Jansen ,  John Kerr ,  Anthony Baiada

IPC分类号： C13K1/08

CPC分类号： C13K3/00 ,  C13B20/14

摘要： We disclose a method of inverting sucrose, including (i) determining an initial solids concentration of an aqueous sucrose solution (solidsi), an initial bed volume (BVi) of a sucrose inversion resin system, a minimum target inversion percentage (invert %min), a maximum target inversion percentage (invert %max), a target maximum hydroxymethylfuran (HMF) concentration (HMFmax), a minimum target pH (pHmin), or a maximum target pH (pHmax); (ii) contacting the sucrose inversion resin system with the aqueous sucrose solution under conditions of aqueous solution flow rate in BVi/hr (ratep) and aqueous solution temperature in ° C. (temperaturep) to produce an inverted sucrose solution having an inversion percentage (invert %product), an HMF concentration (HMFproduct), and a pH (pHproduct); (iii) observing an instantaneous inversion percentage (invert %inst), an instantaneous HMF concentration (HMFinst), or an instantaneous pH (pHinst) of the inverted sucrose solution; and, if invert %inst invert %max, HMFinst>HMFmax, pHinst pHmax; (iv) changing at least one of the aqueous solution flow rate or the aqueous solution temperature such that invert %min≦invert %product≦invert %max, HMFproduct≦HMFmax, or pHmin≦pHproduct≦pHmax. We also disclose a computing apparatus capable of use in performing a method of inverting sucrose.

摘要翻译： 我们公开了一种蔗糖翻转方法，包括（i）测定蔗糖反应树脂体系的初始固体浓度，蔗糖反转树脂体系的初始床体积（BVi），最小目标反转百分比（反转百分比） ，最大目标反转百分比（反转百分比最大值），目标最大羟甲基呋喃（HMF）浓度（HMFmax），最小目标pH（pHmin）或最大目标pH（pHmax））; （ii）在水溶液流速（BVi / hr（速率））和水溶液温度（℃）（℃）下的条件下，将蔗糖反转树脂体系与蔗糖溶液的蔗糖溶液接触，得到反转百分比的倒转蔗糖溶液 转化％产物），HMF浓度（HMF产物）和pH（pH值产物）; （iii）观察反转蔗糖溶液的瞬时反转百分率（反转％inst），瞬时HMF浓度（HMFinst）或瞬时pH（pHinst）; 并且，如果反转％inst invert％max，HMFinst> HMFmax，pHinst pHmax; （iv）改变水溶液流速或水溶液温度中的至少一个，使得反相％min和nlE反相％max，HMFproduct＆NlE; HMFmax或pHmin＆amp; NlE; pH值＆amp; NlE; pHmax。 我们还公开了一种能够用于执行蔗糖翻转方法的计算装置。

公开(公告)号：US20090299054A1

公开(公告)日：2009-12-03

申请号：US12413955

申请日：2009-03-30

申请人： Robert Jansen ,  Gordon Walker ,  John Kerr ,  Anthony Baiada

发明人： Robert Jansen ,  Gordon Walker ,  John Kerr ,  Anthony Baiada

IPC分类号： C13K13/00

CPC分类号： C07H5/02

摘要： A process for the extraction of sucralose from an aqueous solution containing at least sucralose, other chlorinated saccharides, sodium chloride and dimethylammonium chloride into an organic solvent for sucralose by contacting said organic solvent with said solution to extract sucralose into the organic solvent. The ratio of sodium chloride to dimethylammonium chloride in the aqueous solution is increased prior to or during contact so as to increase the partition coefficient of sucralose into said organic solvent.

摘要翻译： 通过使所述有机溶剂与所述溶液接触将三氯半乳蔗糖，其它氯化糖，氯化钠和二甲基氯化铵的水溶液提取到三氯半乳蔗糖的有机溶剂中以将三氯蔗糖萃取到有机溶剂中的方法。 在接触之前或接触期间，水溶液中氯化钠与二甲基氯化铵的比例增加，从而增加三氯蔗糖分配成所述有机溶剂的分配系数。

公开(公告)号：US20120157676A1

公开(公告)日：2012-06-21

申请号：US13262147

申请日：2010-03-24

申请人： John Kerr ,  Robert Jansen ,  Anthony Baiada ,  Duane Leinhos ,  James Edwin Wiley

发明人： John Kerr ,  Robert Jansen ,  Anthony Baiada ,  Duane Leinhos ,  James Edwin Wiley

IPC分类号： C07C209/86 ,  C07H1/06

CPC分类号： C07H5/02

摘要： A process for removing dimethylamine (DMA) before and/or during and/or after deacylation in a reaction vessel of a feed stream comprising a sucralose-6-acylate resulting from the chlorination of a sucrose-6-acylate in the presence of dimethyl formamide (DMF), wherein the deacylation is conducted at a first set of conditions of temperature, pH and pressure, the process comprising: (a) providing a side stream loop from and to the reaction vessel; (b) adjusting the conditions of one or more of temperature, pH, and pressure in the loop, and setting the flow rate through the loop, to remove DMA while minimising carbohydrate degradation.

摘要翻译： 在二甲基甲酰胺存在下，在包含由蔗糖-6-酰化物氯化得到的三氯半氯蔗糖-6-酰化物的进料流的反应容器中脱酰基之前和/或之前和/或之后除去二甲胺（DMA）的方法 （DMF），其中所述脱酰基在温度，pH和压力的第一组条件下进行，所述方法包括：（a）从反应容器提供侧流回路; （b）调节循环中的一个或多个温度，pH和压力的条件，并设定流过循环的流速，以除去DMA同时使碳水化合物降解最小化。