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公开(公告)号：US12235219B2
公开(公告)日：2025-02-25
申请号：US18516492
申请日：2023-11-21
Applicant: Roche Diabetes Care, Inc.
Inventor： Bernhard Limburg , Max Berg , Fredrik Hailer , Volker Tuerck , Daria Skuridina , Irina Ostapenko
IPC: G01N21/84
Abstract: A method of determining analyte concentration in a body fluid with a mobile device having a camera. A user is prompted to apply body fluid to an optical test strip and then waits a predetermined minimum waiting time. The camera captures an image of part of the test field having the body fluid applied thereto. Analyte concentration is determined based on the image captured. The determination includes estimating a point in time of sample application to the test field by taking into account time-dependent information derived from the image captured using a first color channel of a color space. The determination also estimates the concentration of the analyte by taking into account concentration-dependent information derived from the image using a second color channel of the color space.
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公开(公告)号：US11928814B2
公开(公告)日：2024-03-12
申请号：US17343513
申请日：2021-06-09
Applicant: Roche Diabetes Care, Inc.
Inventor： Max Berg , Fredrik Hailer , Bernd Limburg , Daniel Sieffert , Herbert Wieder , Peter Seelig , Benhur Aysin , Siva Chittajallu
CPC classification number: G06T7/0012 , G01N33/66 , G06T5/50 , G06T7/11 , G06T7/90 , G06T2207/20084 , G06T2207/30024
Abstract: A method for generating a module configured to determine concentration of an analyte in a sample of a body fluid is disclosed. The method includes providing a first set of measurement data derived from images of one or more test strips indicating a color transformation in response to a body fluid containing an analyte. The images can be recorded by multiple devices with differing cameras, software and/or hardware device configurations for image recording and image data processing. A neural network model can be generated in a machine learning process applying an artificial neural network and a module configured to determine concentration of an analyte in a second sample of a body fluid can be generated. Further, the present disclosure includes a system for generating the module as well as a method and a system for determining concentration of an analyte in a sample of a bodily fluid.
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公开(公告)号：US11906436B2
公开(公告)日：2024-02-20
申请号：US17334284
申请日：2021-05-28
Applicant: Roche Diabetes Care, Inc.
Inventor： Bernd Limburg , Max Berg , Fredrik Hailer , Volker Tuerck , Daria Skuridina , Irina Ostapenko
IPC: G01N21/84
CPC classification number: G01N21/8483
Abstract: A method of determining analyte concentration in a body fluid with a mobile device having a camera. A user is prompted to apply body fluid to an optical test strip and then waits a predetermined minimum waiting time. The camera captures an image of part of the test field having the body fluid applied thereto. Analyte concentration is determined based on the image captured. The determination includes estimating a point in time of sample application to the test field by taking into account time-dependent information derived from the image captured using a first color channel of a color space. The determination also estimates the concentration of the analyte by taking into account concentration-dependent information derived from the image using a second color channel of the color space.
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公开(公告)号：US20220283148A1
公开(公告)日：2022-09-08
申请号：US17752597
申请日：2022-05-24
Applicant: Roche Diabetes Care, Inc.
Inventor： Benhur Aysin , Max Berg , Siva Chittajallu
Abstract: A method is disclosed for determining concentration of an analyte in a body fluid with a mobile device having a camera. The camera captures an image of an optical test strip having a test field. The analyte concentration value is determined from color formation of the test field. Provided in the mobile device is a correlation for transforming color formation of the test field into analyte concentration. Also provided in the mobile device is an item of clearance information indicating a level of confidence for the correlation. When the item of clearance information indicates a sufficient level of confidence for the correlation, the mobile device indicates to a user that the capturing of the image does not require using a color reference card. Further disclosed are a method of controlling analytical measurements, a mobile device, a system for controlling analytical measurements and computer programs for performing and/or controlling analytical measurements.
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公开(公告)号：US20210285888A1
公开(公告)日：2021-09-16
申请号：US17334284
申请日：2021-05-28
Applicant: Roche Diabetes Care, Inc.
Inventor： Bernd Limburg , Max Berg , Fredrik Hailer , Volker Tuerck , Daria Skuridina , Irina Ostapenko
IPC: G01N21/84
Abstract: A method of determining analyte concentration in a body fluid with a mobile device having a camera. A user is prompted to apply body fluid to an optical test strip and then waits a predetermined minimum waiting time. The camera captures an image of part of the test field having the body fluid applied thereto. Analyte concentration is determined based on the image captured. The determination includes estimating a point in time of sample application to the test field by taking into account time-dependent information derived from the image captured using a first color channel of a color space. The determination also estimates the concentration of the analyte by taking into account concentration-dependent information derived from the image using a second color channel of the color space.
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Patent Agency Ranking
公开(公告)号：US11067588B2
公开(公告)日：2021-07-20
申请号：US16183177
申请日：2018-11-07
Applicant: Roche Diabetes Care, Inc.
Inventor： Max Berg , Hans Kintzig , Beate Koschorreck
IPC: G01N35/00 , G01N33/487
Abstract: A method for operating a medical analyte testing system having a handheld meter, particularly, a glucose meter, and a test magazine is disclosed. In the disclosed method a replaceable test magazine including a plurality of test elements is provided in the handheld meter for conducting successive analyte tests. An auxiliary measuring unit of the handheld meter measures at various points of time at least one ambient parameter, including temperature or humidity. The method checks for a threshold violation by comparing the measured ambient parameter with a preset threshold. The preset threshold is lowered after an initial period of use of the test magazine, and a use-up period is adjusted based on the check for a threshold violation.
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公开(公告)号：US20210088506A1
公开(公告)日：2021-03-25
申请号：US17118185
申请日：2020-12-10
Applicant: Roche Diabetes Care, Inc.
Inventor： Max Berg , Fredrik Hailer , Timo Klein , Bernd Limburg , Christian Melchinger , Volker Tuerck
Abstract: A method of evaluating suitability of lighting conditions for detecting an analyte in a sample using a mobile device camera. A test strip is provided for detecting the analyte. A first image of the test strip is captured while an illumination source of the mobile device is turned off and a second image of the test strip is captured while the illumination source is turned on. A sample is applied to the test strip and the first and second images are compared to thereby determine the difference in lighting conditions between the first image and the second image. The comparison is used to derive information on suitability of the lighting conditions for analyte detection. The lighting conditions are indicated as suitable when a predetermined threshold amount of light intensity used for illumination of the test strip originates from the illumination source.
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公开(公告)号：US12135292B2
公开(公告)日：2024-11-05
申请号：US17142129
申请日：2021-01-05
Applicant: Roche Diabetes Care, Inc.
Inventor： Max Berg , Daniel Sieffert , Volker Tuerck , Simon Wetzel , Momme Winkelnkemper
IPC: B01L3/00 , B01F23/00 , B01F23/41 , B01F101/23 , B23Q17/24 , C07K14/705 , C12M1/34 , C12Q1/04 , C12Q1/18 , C12Q1/686 , G01N21/3577 , G01N21/359 , G01N21/39 , G01N21/45 , G01N21/64 , G01N21/77 , G01N21/78 , G01N27/414 , G01N30/12 , G01N30/68 , G01N30/70 , G01N30/72 , G01N30/88 , G01N33/00 , G01N33/18 , G01N33/50 , G01N33/53 , G01N33/543 , G01N33/68 , G01N33/74 , G01N35/00 , G01N35/10 , G06T7/00 , G06T7/90 , H10K10/46 , H10K85/00 , H10K85/20
Abstract: A method for detecting an analyte in a sample is disclosed. The method includes providing a mobile device having a camera and an illumination source. A test strip having a test field with at least one test chemical for performing an optical detection reaction in the presence of the analyte is provided. The sample is applied to the test field. Several images of a region of the test strip are captured. The region includes at least part of the test field to which sample is applied. The images are captured before and after the sample is applied and with the illumination source turned on and off. The images captured are compared and differences in light intensities are determined. Analyte concentration is determined using the images captured and the determined light intensities.
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公开(公告)号：US20240085340A1
公开(公告)日：2024-03-14
申请号：US18516492
申请日：2023-11-21
Applicant: Roche Diabetes Care, Inc.
Inventor： Bernd Limburg , Max Berg , Fredrik Hailer , Volker Tuerck , Daria Skuridina , Irina Ostapenko
IPC: G01N21/84
CPC classification number: G01N21/8483
Abstract: A method of determining analyte concentration in a body fluid with a mobile device having a camera. A user is prompted to apply body fluid to an optical test strip and then waits a predetermined minimum waiting time. The camera captures an image of part of the test field having the body fluid applied thereto. Analyte concentration is determined based on the image captured. The determination includes estimating a point in time of sample application to the test field by taking into account time-dependent information derived from the image captured using a first color channel of a color space. The determination also estimates the concentration of the analyte by taking into account concentration-dependent information derived from the image using a second color channel of the color space.
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公开(公告)号：US20230084800A1
公开(公告)日：2023-03-16
申请号：US18054432
申请日：2022-11-10
Applicant: Roche Diabetes Care, Inc.
Inventor： Max Berg , Fredrik Hailer , Bernd Limburg , Volker Tuerck , Momme Winkelnkemper
Abstract: A method of evaluating the quality of a color reference card having multiple color reference fields. The quality refers to whether the color reference card is usable for a method for determining concentration of analyte in a body fluid and/or to the degree of suitability or reliability of the color reference card for use with a method for determining analyte concentration in a body fluid. In the inventive method, an image is captured of at least a part of the color reference card using a mobile device camera. Measured color reference values are determined from the image for one or more of the color reference fields and a relationship between one or more of the measured reference color values and corresponding known reference color values is determined. The determined relationship is used to assess the quality of the color reference card. A kit and mobile device are also disclosed.
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