SEPSIS MANAGEMENT
    2.
    发明申请

    公开(公告)号:US20230030564A1

    公开(公告)日:2023-02-02

    申请号:US17772959

    申请日:2020-10-27

    Abstract: The present invention concerns methods for aiding in the risk assessment of a patient with suspected sepsis. For example, the risk of poor outcome (such as of a complicated clinical course and/or of mortality) can be assessed. The methods of the present invention may comprise the steps of (a) determining the amount of the biomarker Presepsin in a sample from a patient with suspected sepsis who has a known qSOFA (quick Sequential Organ Failure-Assessment) score of 0, 1, 2 or 3, (b) determining the amount of the biomarker Pro-calcitonin (PCT) in a sample from the patient, comparing the amounts determined in steps (b) and (c) to reference amounts, and (d) aiding in the risk assessment of a patient with suspected sepsis. The methods of the present invention may be computer-implemented.

    Prediction and recognition of acute kidney injury after surgery
    4.
    发明授权
    Prediction and recognition of acute kidney injury after surgery 有权
    手术后急性肾损伤的预测与识别

    公开(公告)号:US09535073B2

    公开(公告)日:2017-01-03

    申请号:US13713719

    申请日:2012-12-13

    Abstract: Systems, kits, and methods for predicting the risk of an adverse event related to acute kidney injury AKI as a consequence of a surgical intervention in a subject. Embodiments of the system and methods include means and steps for determining an amount of liver-type fatty acid binding protein (L-FABP) in a sample, such as a urine-sample of a subject; comparing the amounts of the L-FABP with a reference amount, and predicting the risk of an adverse event related to acute kidney injury as a consequence of surgical intervention in the subject.

    Abstract translation: 用于预测与受试者的外科手术相关的急性肾损伤AKI有关的不良事件风险的系统,试剂盒和方法。 该系统和方法的实施方案包括用于测定样品(例如受试者的尿液样品)中肝型脂肪酸结合蛋白(L-FABP)的量的方法和步骤; 将L-FABP的量与参考量进行比较,并且预测与受试者的外科手术相关的与急性肾损伤有关的不良事件的风险。

    NT-proANP AND NT-proBNP FOR THE DIAGNOSIS OF STROKE

    公开(公告)号:US20200333360A1

    公开(公告)日:2020-10-22

    申请号:US16916809

    申请日:2020-06-30

    Abstract: The present invention relates to a method for diagnosing a transitory ischemic attack (TIA) in a subject who is suspected to have exhibited a transitory ischemic attack, but who did not exhibit a stroke. The method is based on the determination of the amount of NT-proANP in a sample from said subject. Moreover, the present invention is directed to a method for diagnosing an acute cerebral ischemic event in a subject based on the determination of the amounts of NT-proBNP and NT-proANP in a sample from a subject. The method further comprises the step of calculating a ratio of the amounts of NT-proBNP and NT-proANP. Further envisaged by the present invention are kits and devices adapted to carry out the method of the present invention.

    NT-proANP and NT-proBNP for the diagnosis of stroke

    公开(公告)号:US10732188B2

    公开(公告)日:2020-08-04

    申请号:US14291676

    申请日:2014-05-30

    Abstract: The present invention relates to a method for diagnosing a transitory ischemic attack (TIA) in a subject who is suspected to have exhibited a transitory ischemic attack, but who did not exhibit a stroke. The method is based on the determination of the amount of NT-proANP in a sample from said subject. Moreover, the present invention is directed to a method for diagnosing an acute cerebral ischemic event in a subject based on the determination of the amounts of NT-proBNP and NT-proANP in a sample from a subject. The method further comprises the step of calculating a ratio of the amounts of NT-proBNP and NT-proANP. Further envisaged by the present invention are kits and devices adapted to carry out the method of the present invention.

    NT-proANP AND NT-proBNP FOR THE DIAGNOSIS OF STROKE
    10.
    发明申请
    NT-proANP AND NT-proBNP FOR THE DIAGNOSIS OF STROKE 审中-公开
    NT-proANP和NT-proBNP用于诊断STROKE

    公开(公告)号:US20140274793A1

    公开(公告)日:2014-09-18

    申请号:US14291676

    申请日:2014-05-30

    Abstract: The present invention relates to a method for diagnosing a transitory ischemic attack (TIA) in a subject who is suspected to have exhibited a transitory ischemic attack, but who did not exhibit a stroke. The method is based on the determination of the amount of NT-proANP in a sample from said subject. Moreover, the present invention is directed to a method for diagnosing an acute cerebral ischemic event in a subject based on the determination of the amounts of NT-proBNP and NT-proANP in a sample from a subject. The method further comprises the step of calculating a ratio of the amounts of NT-proBNP and NT-proANP. Further envisaged by the present invention are kits and devices adapted to carry out the method of the present invention.

    Abstract translation: 本发明涉及一种用于诊断怀疑显示出暂时缺血发作,但没有发生中风的受试者的暂时缺血发作(TIA)的方法。 该方法基于来自所述受试者的样品中NT-proANP的量的确定。 此外,本发明涉及基于来自受试者的样品中NT-proBNP和NT-proANP的量的确定来诊断受试者的急性脑缺血事件的方法。 该方法还包括计算NT-proBNP和NT-proANP的量的比例的步骤。 本发明进一步设想的是适用于实施本发明方法的试剂盒和装置。

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