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    ANALYTICAL TEST MANAGEMENT SYSTEM AND METHOD
    1.
    发明申请
    ANALYTICAL TEST MANAGEMENT SYSTEM AND METHOD 审中-公开
    分析测试管理系统与方法

    公开(公告)号：US20170067922A1

    公开(公告)日：2017-03-09

    申请号：US15249834

    申请日：2016-08-29

    Applicant: Roche Diagnostics Operations, Inc.

    Inventor： Sascha Martin Antoni ,  Martin Burri ,  Werner Doeppen ,  Bernhard Eckert ,  Elke Faatz ,  Barbara Upmeier ,  Andreas Woeste ,  Dieter Roessler ,  Elena Pfaffenrot

    IPC: G01N35/00 ,  G01N35/10

    CPC classification number: G01N35/0092 ,  G01N35/00613 ,  G01N35/00712 ,  G01N35/00871 ,  G01N35/0095 ,  G01N35/1072 ,  G01N2035/00326 ,  G01N2035/00881 ,  G01N2035/0091 ,  G01N2035/1032 ,  G05B19/042 ,  G05B2219/32258 ,  Y02P90/20

    Abstract: A test management system is presented. The system comprises an analyzer to perform tests a sample according to a first set of instructions, a manager module connected to the analyzer, and a first order interface connected to the manager module. The manager module directs activity of the analyzer according to a second set of instructions. The first order interface receives an order for a first analytical test and a second analytical test and transmits the order to the manager module. If the order is for the first analytical test, the test manager module forwards the order directly to the analyzer and the sample is analyzed by the analyzer according to the first set of instructions. If the order is for the second analytical test, the manager module handles the order according to the second set of instructions and generates and transmits secondary test requests to the analyzer.

    Abstract translation: 提出了一个测试管理系统。 该系统包括分析器，用于根据第一组指令执行样本测试，连接到分析器的管理器模块以及连接到管理器模块的第一阶接口。 管理器模块根据第二组指令指示分析仪的活动。 第一订单接口接收第一分析测试和第二分析测试的订单，并将该订单发送给管理器模块。 如果订单是第一次分析测试，则测试管理器模块将订单直接转发到分析仪，并且分析仪根据第一组指令对样品进行分析。 如果订单用于第二次分析测试，则管理器模块根据第二组指令处理订单，并生成并传送二次测试请求给分析仪。

    Recombinant Trypanosoma cruzi JL7 antigen variants and their use for detecting Chagas disease
    3.
    发明授权
    Recombinant Trypanosoma cruzi JL7 antigen variants and their use for detecting Chagas disease 有权

    公开(公告)号：US10228370B2

    公开(公告)日：2019-03-12

    申请号：US15587907

    申请日：2017-05-05

    Applicant: Roche Diagnostics Operations, Inc.

    Inventor： Dieter Roessler ,  Barbara Upmeier ,  Toralf Zarnt

    IPC: G01N33/569 ,  C07K14/44 ,  G01N33/564

    Abstract: The invention concerns variants of JL7 antigens that are suitable for detecting antibodies against Trypanosoma cruzi (causing Chagas disease) in an isolated biological sample. These antigens comprise a JL7 specific amino acid sequence, said JL7 specific sequence consisting of two copies of SEQ ID NO. 2, wherein each of said two copies has an amino acid identity of at least 90% to SEQ ID NO.2 and wherein no further Trypanosoma cruzi specific amino acid sequences are present in said polypeptide. The invention also concerns a composition of polypeptides useful for the detection of antibodies against Trypanosoma cruzi that comprises the above characterized JL7 antigen along with at least one of T. cruzi polypeptides 1F8, Cruzipain, KMP-11 and PAR-2. Moreover, it relates to a method for producing JL7 antigen as well as to diagnostic methods for detecting T. cruzi antibodies using the JL7 polypeptide. In addition, the invention concerns a reagent kit comprising said JL7 polypeptides or composition of Trypanosoma cruzi polypeptides.

    Analytical test management system and method
    6.
    发明授权
    Analytical test management system and method 有权

    公开(公告)号：US10101349B2

    公开(公告)日：2018-10-16

    申请号：US15249834

    申请日：2016-08-29

    Applicant: Roche Diagnostics Operations, Inc.

    Inventor： Sascha Martin Antoni ,  Martin Burri ,  Werner Doeppen ,  Bernhard Eckert ,  Elke Faatz ,  Barbara Upmeier ,  Andreas Woeste ,  Dieter Roessler ,  Elena Pfaffenrot

    IPC: G01N35/00 ,  G01N35/10 ,  G05B19/042

    Abstract: A test management system is presented. The system comprises an analyzer to perform tests a sample according to a first set of instructions, a manager module connected to the analyzer, and a first order interface connected to the manager module. The manager module directs activity of the analyzer according to a second set of instructions. The first order interface receives an order for a first analytical test and a second analytical test and transmits the order to the manager module. If the order is for the first analytical test, the test manager module forwards the order directly to the analyzer and the sample is analyzed by the analyzer according to the first set of instructions. If the order is for the second analytical test, the manager module handles the order according to the second set of instructions and generates and transmits secondary test requests to the analyzer.

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