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公开(公告)号:US20140329249A1
公开(公告)日:2014-11-06
申请号:US14261678
申请日:2014-04-25
发明人: Judith Brand-Meier , Claudio Cherubini , Andreas Drechsler , Nicole Gwerder , Martin Kopp , Edwin Oosterbroek , Emad Sarofim
IPC分类号: G01N1/44
CPC分类号: G01N1/44 , C12M33/00 , G01N33/54353
摘要: A method of individually releasing from an entity one or more members of a sub-group of biological units included in a heterogeneous group of biological units is provided. The method includes binding the group of biological units including the sub-group of biological units to the entity via a linker. Following binding, the location of the one or more members on the entity is determined. Once the location is determined, a localized physical pulse is applied to the one or more members. The localized physical pulse individually releases the one or more members from the entity by dissociating the linker.
摘要翻译: 提供了从实体单独地释放包含在生物单元的异质组中的生物单元子组的一个或多个成员的方法。 该方法包括通过接头将包括生物单元亚组的生物单元组结合到实体。 在绑定之后,确定实体上的一个或多个成员的位置。 一旦确定了位置,就将本地化的物理脉冲施加到一个或多个成员。 本地化的物理脉冲通过解离接头单独地从实体释放一个或多个成员。
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公开(公告)号:US09638612B2
公开(公告)日:2017-05-02
申请号:US14261678
申请日:2014-04-25
发明人: Judith Brand-Meier , Claudio Cherubini , Andreas Drechsler , Nicole Gwerder , Martin Kopp , Edwin Oosterbroek , Emad Sarofim
IPC分类号: C40B80/00 , C40B40/02 , G01N1/44 , G01N33/567 , G01N33/574 , G01N33/543
CPC分类号: G01N1/44 , C12M33/00 , G01N33/54353
摘要: A method of individually releasing from an entity one or more members of a sub-group of biological units included in a heterogeneous group of biological units is provided. The method includes binding the group of biological units including the sub-group of biological units to the entity via a linker. Following binding, the location of the one or more members on the entity is determined. Once the location is determined, a localized physical pulse is applied to the one or more members. The localized physical pulse individually releases the one or more members from the entity by dissociating the linker.
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