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公开(公告)号：US20180056297A1
公开(公告)日：2018-03-01
申请号：US15693009
申请日：2017-08-31
CPC分类号： B01L7/52 , B01L3/5085 , B01L9/06 , B01L2200/025 , B01L2300/0829 , B01L2300/1805 , B01L2300/1822 , B01L2300/1894 , C12P19/34 , H01L23/38 , H01L27/16 , H05B3/10
摘要： An assembly (10) comprising a sample block (12), a heat sink (30) and at least one electrodeposited thermoelectric element (48) is disclosed. Further, an instrument and a method for performing a temperature-dependent reaction are disclosed.
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公开(公告)号：US09365895B2
公开(公告)日：2016-06-14
申请号：US13962824
申请日：2013-08-08
IPC分类号： C12M1/34 , C12M3/00 , C12M1/00 , G01N15/06 , G01N33/00 , G01N33/48 , C12Q1/68 , B01L7/00 , G01N35/00 , B01L3/02 , B01L9/00
CPC分类号： C12Q1/6848 , B01L3/0275 , B01L7/52 , B01L9/543 , B01L2200/025 , B01L2200/028 , B01L2200/141 , B01L2300/04 , B01L2300/044 , B01L2400/043 , G01N35/0098 , G01N35/0099 , G01N2035/00277 , G01N2035/00326 , Y10T436/11
摘要： An automated nucleic acid analysis method and analytical system are described comprising separate modules, wherein the air flow of any one of said modules is controlled and wherein at least the air flow between the module for isolation and purification of the analyte and the module for analysis of the analyte are separated.
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公开(公告)号：US08809039B2
公开(公告)日：2014-08-19
申请号：US13962818
申请日：2013-08-08
CPC分类号： C12Q1/6848 , B01L3/0275 , B01L7/52 , B01L9/543 , B01L2200/025 , B01L2200/028 , B01L2200/141 , B01L2300/04 , B01L2300/044 , B01L2400/043 , G01N35/0098 , G01N35/0099 , G01N2035/00277 , G01N2035/00326 , Y10T436/11
摘要： An automated nucleic acid analysis method and analytical system are described comprising separate modules, wherein the air flow of any one of said modules is controlled and wherein at least the air flow between the module for isolation and purification of the analyte and the module for analysis of the analyte are separated.
摘要翻译： 描述了自动化核酸分析方法和分析系统，其包括单独的模块，其中控制任何一个所述模块的空气流，并且其中至少所述模块之间的空气流分离和净化分析物和用于分析的模块 分析物被分离。
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公开(公告)号：US20220168744A1
公开(公告)日：2022-06-02
申请号：US17673116
申请日：2022-02-16
发明人： Thomas Schlaubitz , Torsten Burdack , Paul Federer , Christian George , Guido Grueter , Andreas Scholle , Guenter Tenzler
IPC分类号： B01L7/00
摘要： The present invention relates to the field of high throughput analysis of samples. In particular, the present invention is directed to a device, a System and a method for simultaneous tempering of multiple samples. More particular, the invention relates to the simultaneous thermocycling of multiple samples to perform PCR in a microtiter plate format.
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公开(公告)号：US10884006B2
公开(公告)日：2021-01-05
申请号：US15878648
申请日：2018-01-24
发明人： Daniel Bommer , Thomas Schlaubitz , Pius Studer
摘要： A heating device for heating a thermally fixable sealing cover disposed over the microplate adjacent the wells, a cooling device for actively cooling the microplate and a controller set up to control activity of the heating and cooling devices in a manner to heat the sealing cover so as to thermally fix it to the microplate and to actively cool the microplate so as to keep a temperature of the samples below a predefined temperature when heating the sealing cover. It further relates to a method for automatically sealing a microplate in which the thermally fusible sealing cover is disposed over the microplate, the sealing cover is heated to thermally fix it to the microplate and the microplate is actively cooled in a manner that a temperature of the liquid reaction mixtures is kept below a predefined temperature when heating the sealing cover.
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公开(公告)号：US20190070611A1
公开(公告)日：2019-03-07
申请号：US16058135
申请日：2018-08-08
发明人： Thomas Schlaubitz , Torsten Burdack , Paul Federer , Christian George , Guido Grueter , Andreas Scholle , Guenter Tenzler
IPC分类号： B01L7/00
摘要： The present invention relates to the field of high throughput analysis of samples. In particular, the present invention is directed to a device, a System and a method for simultaneous tempering of multiple samples. More particular, the invention relates to the simultaneous thermocycling of multiple samples to perform PCR in a microtiter plate format.
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公开(公告)号：US11638920B2
公开(公告)日：2023-05-02
申请号：US17673116
申请日：2022-02-16
发明人： Thomas Schlaubitz , Torsten Burdack , Paul Federer , Christian George , Guido Grueter , Andreas Scholle , Guenter Tenzler
IPC分类号： B01L7/00
摘要： The present invention relates to the field of high throughput analysis of samples. In particular, the present invention is directed to a device, a System and a method for simultaneous tempering of multiple samples. More particular, the invention relates to the simultaneous thermocycling of multiple samples to perform PCR in a microtiter plate format.
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公开(公告)号：US11285488B2
公开(公告)日：2022-03-29
申请号：US16058135
申请日：2018-08-08
发明人： Thomas Schlaubitz , Torsten Burdack , Paul Federer , Christian George , Guido Grueter , Andreas Scholle , Guenter Tenzler
IPC分类号： B01L7/00
摘要： The present invention relates to the field of high throughput analysis of samples. In particular, the present invention is directed to a device, a System and a method for simultaneous tempering of multiple samples. More particular, the invention relates to the simultaneous thermocycling of multiple samples to perform PCR in a microtiter plate format.
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公开(公告)号：US10183296B2
公开(公告)日：2019-01-22
申请号：US15693009
申请日：2017-08-31
摘要： An assembly comprising a sample block, a heat sink and at least one electrodeposited thermoelectric element is disclosed. Further, an instrument and a method for performing a temperature-dependent reaction are disclosed.
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公开(公告)号：US20230258676A1
公开(公告)日：2023-08-17
申请号：US18056601
申请日：2022-11-17
发明人： Fabian Baggio , Roman Egli , Christian Ettel , Raphael Gut , Pius Hermann , Nikifor Korjagin , Alexander Meier , Thomas Schlaubitz , Rolf Schneebeli , Simon Siegenthaler , Ivo Daniel Vicente Leitao , Stefan Vollenweider
CPC分类号： G01N35/04 , G01N35/00732 , G01N2035/0412
摘要： A method for introducing a sample rack holding a plurality of sample receptacles into a receiving bay in a housing of an automated analytical system is disclosed. The method is carried out by manually moving the sample rack from a loading position towards a processing position along a lane in the receiving bay, pausing the movement when the rack reaches a focusing position, moving a reader to focuse onto the lane, resuming the movement of the sample rack and detecting features of the sample rack during the movement, positioning, detecting, and locking the sample rack in the processing position, and processing the content of the sample receptacles.
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