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公开(公告)号：US4559951A
公开(公告)日：1985-12-24
申请号：US445240
申请日：1982-11-29
申请人： Roger W. Dahl , David W. Mayer
发明人： Roger W. Dahl , David W. Mayer
CPC分类号： A61N1/056 , A61B5/0422 , A61M2025/004 , A61M2025/0063 , A61M25/005
摘要： A catheter assembly designed for long term or short term implantation in an animal body comprising a flexible tube of a biocompatible polymeric material in which plural electrical conductors are helically wound at a predetermined pitch with the conductors being laterally offset from one another and totally buried between the walls of the tube whereby many conductive signal paths can be established through the catheter without increasing its overall diameter. The inclusion of the helically wound conductors in the walls of the tube also allows the torque transfer, flexibility and structural properties to be tailored to fit a variety of applications. Such a catheter may be used as a cardiac pacer lead assembly or as an instrument for carrying out various diagnostic catheterization procedures.
摘要翻译： 一种设计用于长期或短期植入动物体内的导管组件，其包括生物相容性聚合材料的柔性管，其中多个电导体以预定间距螺旋缠绕，导体彼此横向偏移并完全埋在 管的壁，由此可以通过导管建立许多导电信号路径而不增加其总直径。 将螺旋缠绕的导体包括在管的壁中还允许扭矩传递，柔性和结构特性被定制以适合各种应用。 这样的导管可以用作心脏起搏器引线组件或用作执行各种诊断导管插入程序的器械。
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公开(公告)号：US5554178A
公开(公告)日：1996-09-10
申请号：US427942
申请日：1995-04-26
申请人： Roger W. Dahl , David Lipson
发明人： Roger W. Dahl , David Lipson
CPC分类号： A61N1/05
摘要： An implantable cardiac electrode includes a flexible polymeric substrate, a metallized surface layer of the polymeric substrate forming one or more electrically conductive regions on the surface of the polymeric substrate, and one or more insulated conductors connecting the electrically conductive regions to leads, the leads being connected to a cardiac monitoring and pulse generating system. In one embodiment, the electrically conductive region forms a band on the outer surface of a polymeric tube and is electrically connected to a conductor embedded in the tube. In another embodiment, the electrically conductive region forms a desired configuration on a planar surface of the polymeric substrate, such as a concentric ring or spiral patch configuration. In these and other embodiments, the metallized surface layer includes a surface layer of the polymeric substrate that is impregnated with a metal such that a conductive region is formed in the surface of the otherwise insulative polymeric substrate.
摘要翻译： 可植入心脏电极包括柔性聚合物基底，在聚合物基底的表面上形成一个或多个导电区域的聚合物基底的金属化表面层以及将导电区域连接到引线的一个或多个绝缘导体，引线是 连接到心脏监测和脉冲发生系统。 在一个实施例中，导电区域在聚合物管的外表面上形成带，并且电连接到嵌入管中的导体。 在另一个实施例中，导电区域在聚合物基底的平坦表面上形成期望的构造，例如同心环或螺旋形贴片构型。 在这些和其它实施例中，金属化表面层包括浸渍有金属的聚合物基材的表面层，使得在其它绝缘聚合物基材的表面中形成导电区域。
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公开(公告)号：US5342407A
公开(公告)日：1994-08-30
申请号：US912924
申请日：1992-07-13
CPC分类号： A61N1/05
摘要： Implantable electrodes for defibrillation are formed of pluralities of electrode segments. Each of the segments is relatively long and narrow. The electrode segments can be parallel and spaced apart from one another a distance at least ten times the nominal width, with one end of each segment mounted to a transverse distal portion of an electrically conductive lead coupling the electrode to a defibrillation pulse generator. Alternatively, segments can branch or radiate outwardly from a common junction. In yet another arrangement, electrode segments are portions of a single conductive path at the distal end of a lead from a pulse generator, arranged in either a spiral configuration or a serpentine configuration which can align electrode segments side by side, parallel and spaced apart. The electrode segments can be formed of composite conductors in the form of titanium ribbons or wires with a sputtered outer layer of platinum, or a silver core in a stainless steel tube, with a platinum layer formed onto the tube. The electrodes are highly compliant yet can provide large effective areas for defibrillation, enabling a transthoracic pulsing arrangement of two electrodes on opposite sides of the heart, implanted subcutaneously outside of the thoracic region.
摘要翻译： 用于除颤的可植入电极由多个电极段形成。 每个段都相对长而窄。 电极段可以彼此平行和间隔至少十倍于标称宽度的距离，每个段的一端安装到将电极耦合到除颤脉冲发生器的导电引线的横向远端部分。 或者，片段可以从公共接头向外分支或辐射。 在另一种布置中，电极段是在来自脉冲发生器的引线的远端处的单个导电路径的部分，其布置成螺旋构造或蛇形结构，其可以并排并排隔离电极段。 电极段可以由具有溅射的铂外层或不锈钢管中的银芯的钛带或电线形式的复合导体形成，铂层形成在管上。 电极是高度依从性的，但可以为除颤提供大的有效区域，使得能够在心脏外侧皮下植入心脏两侧的两个电极的经胸部脉冲排列。
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公开(公告)号：US5203348A
公开(公告)日：1993-04-20
申请号：US533886
申请日：1990-06-06
CPC分类号： A61N1/05
摘要： Implantable electrodes for defibrillation are formed of pluralities of electrode segments. Each of the segments is relatively long and narrow. The electrode segments can be parallel and spaced apart from one another a distance at least ten times the nominal width, with one end of each segment mounted to a transverse distal portion of an electrically conductive lead coupling the electrode to a defibrillation pulse generator. Alternatively, segments can branch or radiate outwardly from a common junction. In yet another arrangement, electrode segments are portions of a single conductive path at the distal end of a lead from a pulse generator, arranged in either a spiral configuration or a serpentine configuration which can align electrode segments side by side, parallel and spaced apart. The electrode segments can be formed of composite conductors in the form of titanium ribbons or wires with a sputtered outer layer of platinum, or a silver core in a stainless steel tube, with a platinum layer formed onto the tube. The electrodes are highly compliant yet can provide large effective areas for defibrillation, enabling a transthoracic pulsing arrangement of two electrodes on opposite sides of the heart, implanted subcutaneously outside of the thoracic region.
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公开(公告)号：US5090422A
公开(公告)日：1992-02-25
申请号：US511068
申请日：1990-04-19
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/0587
摘要： A novel method and apparatus for isolating and anchoring an implantable electrically stimulating probe such as a defibrillator patch electrode for use with an automatic cardioverter/defibrillator is disclosed in which a porous bio-compatible coating or enclosure covers and isolates the electrode in a way which allows electrical conductivity via bodily fluid which passes through but separates the electrode from the adjacent tissue in the manner of dissection plane which substantially prevents tissue ingrowth. The coating or enclosure controls the minimum separation distance from the closest tissue and which reduces the local current density applied to adjacent tissue when the electrode is pulsed. The system includes a provision for attaching the enclosure means to internal bodily tissue.
摘要翻译： 公开了用于分离和锚定可植入电刺激探针（例如用于自动心律转复除颤器的除颤器贴片电极）的新颖方法和装置，其中多孔生物相容性涂层或外壳以允许的方式覆盖并隔离电极 穿过体液的导电性通过基本上防止组织向内生长的解剖平面的方式将电极与相邻组织隔开。 涂层或外壳控制距离最近的组织的最小间隔距离，并且当电极被脉冲时减小施加到相邻组织的局部电流密度。 该系统包括用于将外壳装置附接到内部身体组织的装置。
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公开(公告)号：US6157860A
公开(公告)日：2000-12-05
申请号：US344843
申请日：1999-06-28
CPC分类号： A61N1/056 , A61N1/05 , A61N1/368 , A61N1/375 , A61N1/3756
摘要： A pulse generator housing for enclosing and containing pulse generator defibrillation circuitry. The housing is formed entirely of electrically conductive metal defining an electrically conductive outer surface which is connected to the pulse generator circuitry for delivering defibrillating energy to the heart. The pulse generator housing is implanted in the pectoral region proximate the heart with the conductive surface facing the heart. Regions of the conductive outer surface may be electrically isolated and dedicated for separately sensing and shocking. The outer surface may be coated with platinum. Additional coiled segment electrodes may extend from the housing and be electrically connected to the conductive outer surface so as to increase the effective conductive surface area. A sensor is provided to determine whether the housing is inside or outside a body of a patient to disconnect the pulse generator housing conductive surface from the pulse generator circuitry when the unit is outside the body of a patient.
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公开(公告)号：US6038483A
公开(公告)日：2000-03-14
申请号：US243667
申请日：1999-02-02
CPC分类号： A61N1/0587
摘要： Body-implantable leads with open, unbacked (uninsulated) electrode structures having electrical discharge surfaces formed by conductive elements, such as mesh and braid, and preferably coils. The electrode structures can be classified by pattern: (1) loops, (2) linear arrays and (3) radial arrays. The electrodes are located on or near the epicardial surface of the right and left heart.
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公开(公告)号：US5603732A
公开(公告)日：1997-02-18
申请号：US554577
申请日：1995-11-06
CPC分类号： A61N1/05
摘要： Implantable electrodes for defibrillation are formed of pluralities of electrode segments. Each of the segments is relatively long and narrow. The electrode segments can be parallel and spaced apart from one another a distance at least ten times the nominal width, with one end of each segment mounted to a transverse distal portion of an electrically conductive lead coupling the electrode to a defibrillation pulse generator. Alternatively, segments can branch or radiate outwardly from a common junction. In yet another arrangement, electrode segments are portions of a single conductive path at the distal end of a lead from a pulse generator, arranged in either a spiral configuration or a serpentine configuration which can align electrode segments side by side, parallel and spaced apart. The electrode segments can be formed of composite conductors in the form of titanium ribbons or wires with a sputtered outer layer of platinum, or a silver core in a stainless steel tube, with a platinum layer formed onto the tube. The electrodes are highly compliant yet can provide large effective areas for defibrillation, enabling a transthoracic pulsing arrangement of two electrodes on opposite sides of the heart, implanted subcutaneously outside of the thoracic region.
摘要翻译： 用于除颤的可植入电极由多个电极段形成。 每个段都相对长而窄。 电极段可以彼此平行和间隔至少十倍于标称宽度的距离，每个段的一端安装到将电极耦合到除颤脉冲发生器的导电引线的横向远端部分。 或者，片段可以从公共接头向外分支或辐射。 在另一种布置中，电极段是在来自脉冲发生器的引线的远端处的单个导电路径的部分，其布置成螺旋构造或蛇形结构，其可以并排并排隔离电极段。 电极段可以由具有溅射的铂外层或不锈钢管中的银芯的钛带或电线形式的复合导体形成，铂层形成在管上。 电极是高度依从性的，但可以为除颤提供大的有效区域，使得能够在心脏的相对侧上的两个电极的经胸部脉冲排列皮下植入胸部区域。
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公开(公告)号：US5545205A
公开(公告)日：1996-08-13
申请号：US386210
申请日：1995-02-09
申请人： Theodore J. Schulte , Roger W. Dahl , Stanley M. Bach, Jr. , J. Edward Shapland , Douglas J. Lang
发明人： Theodore J. Schulte , Roger W. Dahl , Stanley M. Bach, Jr. , J. Edward Shapland , Douglas J. Lang
CPC分类号： A61N1/056 , A61N1/3918
摘要： A unitary intravascular defibrillating catheter includes distal and proximal spring electrodes, displaced to such distance from one another that defibrillating shock is effected through a field including the interventricular septum and left ventricular free wall. In one embodiment of this catheter, the proximal electrode is placed in the region of the subclavian vein. Alternatively, it may be placed in the region of the third through seventh intercostal space. A unitary catheter is also described which includes an intermediate electrode, placed between distal and proximal electrodes. Selection of placement of electrodes either in the superior vena cava or in the region of the subclavian vein is medically indicated by physiological conditions of the individual patient. The cardioversion system further includes a unipolar or bipolar sensing circuit with at least one sensing electrode, and a cardioversion/defibrillation circuit with either two or three spaced apart spring electrodes. The sensing electrodes are spaced apart from one another, but they are kept sufficiently close to one another for isolated, localized R-wave sensing. The sensing electrodes further are positioned remotely of the cardioversion/defibrillation electrodes, to avoid post-shock abnormalities which otherwise would interfere with a timely R-wave sensing, and to substantially prevent the discharge of an unnecessary cardioversion pulse after return of the heart to normal cardiac rhythm.
摘要翻译： 单一的血管内除颤导管包括远端和近端的弹簧电极，彼此相距移动，使得去纤维化的休克通过包括室间隔和左心室游离壁的场进行。 在该导管的一个实施例中，近端电极被放置在锁骨下静脉的区域中。 或者，其可以放置在第三至第七肋间空间的区域中。 还描述了包括放置在远端和近端电极之间的中间电极的单一导管。 在上腔静脉或锁骨下静脉区域中放置电极的选择由个体患者的生理条件医学指示。 心脏复律系统还包括具有至少一个感测电极的单极或双极检测电路，以及具有两个或三个间隔开的弹簧电极的心电复律/除颤电路。 感测电极彼此间隔开，但它们彼此保持足够接近以进行隔离的局部R波感测。 感测电极进一步位于心脏复律/除颤电极的远端，以避免冲击后异常，否则将干扰及时的R波感测，并且在将心脏恢复正常后基本上防止不必要的心脏复律脉冲的放电 心律
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公开(公告)号：US5545202A
公开(公告)日：1996-08-13
申请号：US285802
申请日：1994-08-04
CPC分类号： A61N1/05
摘要： Implantable electrodes for defibrillation are formed of pluralities of electrode segments. Each of the segments is relatively long and narrow. The electrode segments can be parallel and spaced apart from one another a distance at least ten times the nominal width, with one end of each segment mounted to a transverse distal portion of an electrically conductive lead coupling the electrode to a defibrillation pulse generator. Alternatively, segments can branch or radiate outwardly from a common junction. In yet another arrangement, electrode segments are portions of a single conductive path at the distal end of a lead from a pulse generator, arranged in either a spiral configuration or a serpentine configuration which can align electrode segments side by side, parallel and spaced apart. The electrode segments can be formed of composite conductors in the form of titanium ribbons or wires with a sputtered outer layer of platinum, or a silver core in a stainless steel tube, with a platinum layer formed onto the tube. The electrodes are highly compliant yet can provide large effective areas for defibrillation, enabling a transthoracic pulsing arrangement of two electrodes on opposite sides of the heart, implanted subcutaneously outside of the thoracic region.
摘要翻译： 用于除颤的可植入电极由多个电极段形成。 每个段都相对长而窄。 电极段可以彼此平行和间隔至少十倍于标称宽度的距离，每个段的一端安装到将电极耦合到除颤脉冲发生器的导电引线的横向远端部分。 或者，片段可以从公共接头向外分支或辐射。 在另一种布置中，电极段是在来自脉冲发生器的引线的远端处的单个导电路径的部分，其布置成螺旋构造或蛇形结构，其可以并排并排隔离电极段。 电极段可以由具有溅射的铂外层或不锈钢管中的银芯的钛带或电线形式的复合导体形成，铂层形成在管上。 电极是高度依从性的，但可以为除颤提供大的有效区域，使得能够在心脏外侧皮下植入心脏两侧的两个电极的经胸部脉冲排列。
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