-
公开(公告)号：US20110080581A1
公开(公告)日：2011-04-07
申请号：US12900172
申请日：2010-10-07
Applicant: Rohit Bhargava , Brian T. Cunningham
Inventor： Rohit Bhargava , Brian T. Cunningham
CPC classification number: G01J3/12 , G01J3/02 , G01J3/0202 , G01J3/0275 , G01J3/0286 , G01J3/0289 , G01N21/35
Abstract: Described herein are spectrometers comprising one or more wavelength-selective filters, such as guided mode resonance filters. Some of the spectrometers described herein are configured for obtaining absorbance spectra in a discrete fashion by measuring absorbances of a sample at multiple discrete wavelengths or wavelength bands. In another aspect, methods are also provided for obtaining spectra, images and chemical maps of samples in a discrete fashion.
Abstract translation: 这里描述的是包括一个或多个波长选择滤光器的光谱仪，例如导模谐振滤波器。 这里描述的一些光谱仪被配置为通过测量在多个离散波长或波长带上的样品的吸光度以离散的方式获得吸收光谱。 在另一方面，还提供了用于以离散方式获得样品的光谱，图像和化学图谱的方法。
-
公开(公告)号：US08593630B2
公开(公告)日：2013-11-26
申请号：US12900172
申请日：2010-10-07
Applicant: Rohit Bhargava , Brian T. Cunningham
Inventor： Rohit Bhargava , Brian T. Cunningham
IPC: G01J3/40
CPC classification number: G01J3/12 , G01J3/02 , G01J3/0202 , G01J3/0275 , G01J3/0286 , G01J3/0289 , G01N21/35
Abstract: Described herein are spectrometers comprising one or more wavelength-selective filters, such as guided mode resonance filters. Some of the spectrometers described herein are configured for obtaining absorbance spectra in a discrete fashion by measuring absorbances of a sample at multiple discrete wavelengths or wavelength bands. In another aspect, methods are also provided for obtaining spectra, images and chemical maps of samples in a discrete fashion.
Abstract translation: 这里描述的是包括一个或多个波长选择性滤波器的光谱仪，例如导模谐振滤波器。 这里描述的一些光谱仪被配置为通过测量在多个离散波长或波长带上的样品的吸光度以离散的方式获得吸收光谱。 在另一方面，还提供了用于以离散方式获得样品的光谱，图像和化学图谱的方法。
-
3.发明申请公开(公告)号：US20120290607A1
公开(公告)日：2012-11-15
申请号：US13353196
申请日：2012-01-18
Applicant: Rohit Bhargava , Jin Tae Kwak , Saurabh Sinha
Inventor： Rohit Bhargava , Jin Tae Kwak , Saurabh Sinha
IPC: G06F17/30
CPC classification number: G06F19/345 , G06F19/00 , G16H50/20 , G16H50/70
Abstract: This application provides to a method for identifying one or more prostate tissue samples in a database that are closest to a test prostate sample, which can be used to aid pathologists when examining prostate tissues to attain reliable and consistent diagnoses of prostate cancer. Also provided are databases and computer algorithms that can be used with such methods.
Abstract translation: 本申请提供了一种用于鉴定数据库中最接近测试前列腺样品的一个或多个前列腺组织样品的方法，其可用于在检查前列腺组织时帮助病理学家以获得前列腺癌的可靠和一致的诊断。 还提供了可以与这些方法一起使用的数据库和计算机算法。
-
公开(公告)号：US20120226709A1
公开(公告)日：2012-09-06
申请号：US13344461
申请日：2012-01-05
Applicant: Rohit Bhargava , Jin Tae Kwak , Saurabh Sinha
Inventor： Rohit Bhargava , Jin Tae Kwak , Saurabh Sinha
IPC: G06F17/30
CPC classification number: G06K9/0014 , G06K9/00134 , G06K9/6228 , G06K9/6289 , G06T7/0012 , G06T7/60 , G06T2207/30081
Abstract: This application provides to a method for identifying one or more prostate tissue samples in a database that are closest to a test prostate sample, which can be used to aid pathologists when examining prostate tissues to attain reliable and consistent diagnoses of prostate cancer. Also provided are databases and computer algorithms that can be used with such methods.
-
5.发明申请公开(公告)号：US20150268226A1
公开(公告)日：2015-09-24
申请号：US13090384
申请日：2011-04-20
Applicant: Rohit Bhargava , Saurabh Sinha , Jin Tae Kwak
Inventor： Rohit Bhargava , Saurabh Sinha , Jin Tae Kwak
CPC classification number: G01N33/5091 , G01N2021/3595 , G01N2800/7028
Abstract: The present disclosure relates to methods of diagnosing prostate cancer using different imaging methods. For example, it is shown herein that combining a Fourier transform infrared (FT-IR) spectroscopic image with an optical image (such as a hematoxylin and eosin image) allows for automated detection of prostate cancer with high accuracy.
Abstract translation: 本公开涉及使用不同成像方法诊断前列腺癌的方法。 例如，这里示出了将傅里叶变换红外（FT-IR）光谱图像与光学图像（例如苏木精和曙红图像）组合允许以高精度自动检测前列腺癌。
-
Patent Agency Ranking
6.发明授权Tailored raman spectrocopic probes for ultrasensitive and highly multiplexed assays 有权定制的拉曼光谱探针用于超敏感和高度多重测定公开(公告)号：US08873038B2
公开(公告)日：2014-10-28
申请号：US13277674
申请日：2011-10-20
Applicant: Anil K. Kodali , Xavier Llora , Rohit Bhargava
Inventor： Anil K. Kodali , Xavier Llora , Rohit Bhargava
CPC classification number: B01J13/22 , B82Y15/00 , B82Y40/00 , C09B67/0007 , C09B67/0097 , G01N21/658
Abstract: Embodiments of nanostructured, multilayered metal-dielectric particles suitable for use as Raman spectroscopic probes are disclosed, as well as methods of designing, making and using such multilayered nanoparticles, and kits including the multilayered nanoparticles. The multilayered nanoparticles include alternating metal and dielectric layers and an outer dielectric shell. One or more of the dielectric layers may include a plurality of reporter molecules. Embodiments of the multilayered nanoparticles are suitable for detecting target analytes in a sample. Some embodiments of the multilayered nanoparticles are suitable for use in multiplexed assays, including assays for multiple target analytes having differing concentrations.
Abstract translation: 公开了适合用作拉曼光谱探针的纳米结构多层金属 - 电介质颗粒的实施方案，以及设计，制备和使用这种多层纳米颗粒的方法，以及包括多层纳米颗粒的试剂盒。 多层纳米颗粒包括交替的金属和电介质层和外部电介质外壳。 介电层中的一个或多个可包括多个报道分子。 多层纳米颗粒的实施方案适用于检测样品中的目标分析物。 多层纳米颗粒的一些实施方案适用于多重测定，包括具有不同浓度的多种目标分析物的测定。
-
公开(公告)号：US09779283B2
公开(公告)日：2017-10-03
申请号：US13344461
申请日：2012-01-05
Applicant: Rohit Bhargava , Jin Tae Kwak , Saurabh Sinha
Inventor： Rohit Bhargava , Jin Tae Kwak , Saurabh Sinha
CPC classification number: G06K9/0014 , G06K9/00134 , G06K9/6228 , G06K9/6289 , G06T7/0012 , G06T7/60 , G06T2207/30081
Abstract: This application provides to a method for identifying one or more prostate tissue samples in a database that are closest to a test prostate sample, which can be used to aid pathologists when examining prostate tissues to attain reliable and consistent diagnoses of prostate cancer. Also provided are databases and computer algorithms that can be used with such methods.
-
8.发明申请TAILORED RAMAN SPECTROCOPIC PROBES FOR ULTRASENSITIVE AND HIGHLY MULTIPLEXED ASSAYS 有权用于超声波和高度多重测试的定制拉曼光谱探测器公开(公告)号：US20120212733A1
公开(公告)日：2012-08-23
申请号：US13277674
申请日：2011-10-20
Applicant: Anil K. Kodali , Xavier Llora , Rohit Bhargava
Inventor： Anil K. Kodali , Xavier Llora , Rohit Bhargava
CPC classification number: B01J13/22 , B82Y15/00 , B82Y40/00 , C09B67/0007 , C09B67/0097 , G01N21/658
Abstract: Embodiments of nanostructured, multilayered metal-dielectric particles suitable for use as Raman spectroscopic probes are disclosed, as well as methods of designing, making and using such multilayered nanoparticles, and kits including the multilayered nanoparticles. The multilayered nanoparticles include alternating metal and dielectric layers and an outer dielectric shell. One or more of the dielectric layers may include a plurality of reporter molecules. Embodiments of the multilayered nanoparticles are suitable for detecting target analytes in a sample. Some embodiments of the multilayered nanoparticles are suitable for use in multiplexed assays, including assays for multiple target analytes having differing concentrations.
Abstract translation: 公开了适合用作拉曼光谱探针的纳米结构多层金属 - 电介质颗粒的实施方案，以及设计，制备和使用这种多层纳米颗粒的方法，以及包括多层纳米颗粒的试剂盒。 多层纳米颗粒包括交替的金属和电介质层和外部电介质外壳。 介电层中的一个或多个可包括多个报道分子。 多层纳米颗粒的实施方案适用于检测样品中的目标分析物。 多层纳米颗粒的一些实施方案适用于多重测定，包括具有不同浓度的多种目标分析物的测定。
-
公开(公告)号：US20120116739A1
公开(公告)日：2012-05-10
申请号：US12941159
申请日：2010-11-08
Applicant: Brynmor J. Davis , Paul Scott Carney , Rohit Bhargava
Inventor： Brynmor J. Davis , Paul Scott Carney , Rohit Bhargava
CPC classification number: G01J3/0218 , G01J3/0275
Abstract: Methods and a non-transient computer medium embodying computer readable code for extracting bulk spectroscopic properties of a particle. A forward model is built of an optical field focused on, and interacting with, the particle, where the forward model parameterized in terms of at least one geometrical characteristic of the particle. The particle, which may be a filamentary material, is illuminated with an incident optical field having a spectral range. Either a transmitted or scattered optical field is detected in a far-field zone as a function of wavenumber to obtain a measured spectrum. The measured spectrum is inverted to recover the imaginary part of the complex refractive index of the particle.
Abstract translation: 方法和体现计算机可读代码的非瞬态计算机介质，用于提取粒子的体光谱性质。 正向模型由聚焦在粒子上的光场构成，其中前向模型根据粒子的至少一个几何特征参数化。 可以是具有光谱范围的入射光场照射可以是丝状材料的颗粒。 在远场区域中检测到发射或散射的光场作为波数的函数，以获得测量的光谱。 测量的光谱被反转以恢复颗粒的复折射率的虚部。
-
10.发明授权公开(公告)号：US09230063B2
公开(公告)日：2016-01-05
申请号：US13353196
申请日：2012-01-18
Applicant: Rohit Bhargava , Jin Tae Kwak , Saurabh Sinha
Inventor： Rohit Bhargava , Jin Tae Kwak , Saurabh Sinha
CPC classification number: G06F19/345 , G06F19/00 , G16H50/20 , G16H50/70
Abstract: This application provides to a method for identifying one or more prostate tissue samples in a database that are closest to a test prostate sample, which can be used to aid pathologists when examining prostate tissues to attain reliable and consistent diagnoses of prostate cancer. Also provided are databases and computer algorithms that can be used with such methods.
Abstract translation: 本申请提供了一种用于鉴定数据库中最接近测试前列腺样品的一个或多个前列腺组织样品的方法，其可用于在检查前列腺组织时帮助病理学家以获得前列腺癌的可靠和一致的诊断。 还提供了可以与这些方法一起使用的数据库和计算机算法。
-
-
-
-
-
-
-
-
-
Search Results
12
records
(took 0.021 seconds)
