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30 条记录 (耗时 0.022 秒)

    Method for producing oxime ethers
    2.
    发明授权
    Method for producing oxime ethers 失效
    生产肟醚的方法

    公开(公告)号：US06680410B2

    公开(公告)日：2004-01-20

    申请号：US10257327

    申请日：2002-10-10

    申请人： Roland Götz ,  Bernd Wolf ,  Michael Rack

    发明人： Roland Götz ,  Bernd Wolf ,  Michael Rack

    IPC分类号： C07C25156

    CPC分类号： C07C249/12 ,  C07C251/38

    摘要： A process for preparing oxime ethers of the formula I, in which the substituents R1 and R2 can be identical or different and can each be cyano, alkyl, haloalkyl, cycloalkyl, phenyl and naphthyl, and R3 can be alkyl, by alkylation of oximes of the formula II under basic conditions with an alkylating agent from the group of alkyl halides, dialkyl sulfates and dialkyl carbonates, wherein the reaction is carried out in a mixture consisting of 5 to 25% by weight of polar aprotic solvents selected from the group of nitrites, N-alkylpyrrolidones, cyclic urea derivatives, dimethylformamide and dimethylacetamide, 55 to 95% by weight of nonpolar solvents selected from the group of aliphatic hydrocarbons, aromatic hydrocarbons, alkyl alkylcarboxylates and ethers, and 0 to 25% by weight of water, the contents thereof totaling 100%.

    摘要翻译： 制备式I的肟醚的方法，其中取代基R 1和R 2可以相同或不同，并且各自可以是氰基，烷基，卤代烷基，环烷基，苯基和萘基，R 3， 可以通过烷基化剂从烷基卤化物，二烷基硫酸盐和碳酸二烷基酯在碱性条件下将式II的肟烷基化，其中该反应以5至25重量％的极性非质子 选自亚硝酸盐，N-烷基吡咯烷酮，环脲衍生物，二甲基甲酰胺和二甲基乙酰胺的溶剂，55至95重量％的选自脂族烃，芳烃，烷基烷基羧酸盐和醚的非极性溶剂，和0至25％ 水重量，总含量为100％。

    Method for producing 1-substituted 5-Hydroxypyrazoles
    3.
    发明授权
    Method for producing 1-substituted 5-Hydroxypyrazoles 失效
    1-取代的5-或3-羟基吡唑的制备方法

    公开(公告)号：US06392058B1

    公开(公告)日：2002-05-21

    申请号：US09856201

    申请日：2001-05-17

    申请人： Volker Maywald ,  Adrian Steinmetz ,  Michael Rack ,  Norbert Götz ,  Roland Götz ,  Jochem Henkelmann ,  Heike Becker ,  Juan Jose Aiscar Bayeto

    发明人： Volker Maywald ,  Adrian Steinmetz ,  Michael Rack ,  Norbert Götz ,  Roland Götz ,  Jochem Henkelmann ,  Heike Becker ,  Juan Jose Aiscar Bayeto

    IPC分类号： C07D23120

    CPC分类号： C07D231/20

    摘要： The invention relates to a process for preparing 1-substituted 5- and/or 3-hydroxypyrazoles of the formulae I and II in which R1 is C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C3-C6-cycloalkyl or C1-C4-alkoxy, where these groups may be substituted by halogen, C1-C4-alkoxy, phenoxy, C1-C6-alkoxycarbonyl, C1-C6-alkylthiocarbonyl or by a cyclic ring system having 3-14 ring atoms, which comprises reacting an alkyl 3-alkoxyacrylate of the formula III in which R2, R3 independently of one another are C1-C6-alkyl or C3-C6-cycloalkyl with a hydrazine of the formula IV in which R1 is as defined above a) at a pH of 6-11 to give 5-hydroxypyrazoles of the formula I or b) at a pH of 11-14 to give 3-hydroxypyrazoles of the formula II.

    摘要翻译： 本发明涉及一种制备式I和IIin的1-取代的5-和/或3-羟基吡唑的方法，其中R 1为C 1 -C 6 - 烷基，C 2 -C 6 - 烯基，C 2 -C 6 - 炔基，C 3 -C 6 - 环烷基或C 1 -C 4 - 烷氧基，其中这些基团可以被卤素，C 1 -C 4 - 烷氧基，苯氧基，C 1 -C 6 - 烷氧基羰基，C 1 -C 6 - 烷硫基羰基或具有3-14个环原子的环状体系取代， 包括式IIIin的3-烷氧基丙烯酸烷基酯，其中R 2，R 3彼此独立地是C 1 -C 6烷基或C 3 -C 6环烷基与式IVin的肼，其中R 1如上所定义），其pH为6- 11得到式I的5-羟基吡唑）在11-14的pH下，得到式II的3-羟基吡唑。

    Method for producing o-chloromethyl benzenecarbonyl chlorides
    4.
    发明授权
    Method for producing o-chloromethyl benzenecarbonyl chlorides 失效
    邻苯甲酰氯的制备方法

    公开(公告)号：US06734322B1

    公开(公告)日：2004-05-11

    申请号：US10130826

    申请日：2002-05-23

    申请人： Armin Stamm ,  Roland Götz ,  Norbert Götz ,  Jochem Henkelmann ,  Heinz-Josef Kneuper ,  Bernd Wolf

    发明人： Armin Stamm ,  Roland Götz ,  Norbert Götz ,  Jochem Henkelmann ,  Heinz-Josef Kneuper ,  Bernd Wolf

    IPC分类号： C07C5158

    CPC分类号： C07C51/09 ,  C07C63/04

    摘要： The invention relates to a method for producing o-choromethyl benzenecarbonyl chlorides of formula (I), wherein R1-R4 can be the same or different and stand for hydrogen, C1-C4-alkyl, halogen or trifluoromnethyl, by converting benzocondensed lactones of formula (II), wherein R1-R4 have the aforementioned meaning, with gaseous or liquid phosgene and the dimers or trimers thereof. The inventive method is characterized in that the conversion is carried out in the presence of catalytical amounts of a Lewis acid and catalytical amounts of a phosgenation catalyst

    摘要翻译： 本发明涉及一种制备式（I）的邻氯甲基苯甲酰氯的方法，其中R 1 -R 4可以相同或不同，代表氢，C 1 -C 4 - 烷基，卤素或三氟甲基， 通过用气态或液体光气及其二聚体或三聚体转化其中R 1 -R 4具有上述含义的式（II）的苯并二化内酯。 本发明的方法的特征在于转化在催化量的路易斯酸和催化量的光气化催化剂

    Method for producing 1-substituted 5-hydroxpyrazoles
    8.
    发明授权
    Method for producing 1-substituted 5-hydroxpyrazoles 失效
    1-取代的5-羟基吡唑的制备方法

    公开(公告)号：US06600071B2

    公开(公告)日：2003-07-29

    申请号：US10228373

    申请日：2002-08-27

    申请人： Norbert Götz ,  Roland Götz ,  Michael Rack

    发明人： Norbert Götz ,  Roland Götz ,  Michael Rack

    IPC分类号： C07C24330

    CPC分类号： C07C243/30 ,  C07D231/20

    摘要： A process for preparing compounds of the formula I in which R1 is hydrogen, an aliphatic group having 1-8 carbon atoms, Cl-C6-alkoxycarbonyl, Cl-C6-alkylthiocarbonyl or a cyclic ring system having 3-14 ring atoms, and R2 is hydrogen, an aliphatic group having 1-8 carbon atoms, or R1 and R2 together with the carbon atom to which they are bound form a cyclic or bicyclic ring system having 3-14 ring atoms, comprises the preparation of compounds of the formula II in which R3 and R4 are readily detachable groups and R1 and R2 are as defined above, as starting materials or intermediates and the cyclization of these under suitable reaction conditions to give compounds of the formula I. The intermediates of the formula II are novel.

    摘要翻译： 制备式Iin的化合物的方法，其中R1是氢，具有1-8个碳原子的脂族基团，C1-C6-烷氧基羰基，C1-C6-烷硫基羰基或具有3-14个环原子的环状体系，R2是 氢，具有1-8个碳原子的脂族基团，或者R1和R2与它们所连接的碳原子一起形成具有3-14个环原子的环状或双环体系，包括制备式II化合物，其中式 R3和R4是容易拆分的基团，R1和R2如上所定义，作为原料或中间体，并在合适的反应条件下环化，得到式I化合物。式II的中间体是新的。

    Method for the production of 1-substituted 5-hydroxypyrazoles
    10.
    发明授权
    Method for the production of 1-substituted 5-hydroxypyrazoles 失效
    1-取代的5-羟基吡唑的制备方法

    公开(公告)号：US06329530B1

    公开(公告)日：2001-12-11

    申请号：US09830948

    申请日：2001-05-03

    申请人： Volker Maywald ,  Adrian Steinmetz ,  Michael Rack ,  Norbert Götz ,  Roland Götz ,  Jochem Henkelmann ,  Heike Becker ,  Juan Jose Aiscar Bayeto

    发明人： Volker Maywald ,  Adrian Steinmetz ,  Michael Rack ,  Norbert Götz ,  Roland Götz ,  Jochem Henkelmann ,  Heike Becker ,  Juan Jose Aiscar Bayeto

    IPC分类号： C07D23120

    CPC分类号： C07D231/20

    摘要： The invention relates to a method for the production of 1-substituted 5-hydroxypyrazoles of formula (I) wherein R1 is C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkinyl, C3-C6-cycloalkyl or C1-C4-alkoxy, whereby these groups can be substituted by halogen, C1-C4-alkoxy, phenoxy, C1-C6-alkoxycarbonyl, C1-C6-alkylthiocarbonyl or a cyclic ring system with 3-14 ring atoms, by reacting a) an alkylvinylether of general formula (III) wherein R2 is C1-C6-alkyl or C3-C6-cycloalkyl, with phosgene (IVa), “diphosgene” (IVb) or “triphosgene” (IVc) to form acid chlorides of formula (V), b) transforming said acid chlorides by eliminating hydrogen chloride into the corresponding 3-alkoxyacrylic acid chloride of formula (VI) and c) reacting said acid chloride with hydrazines of formula (VII) wherein R1 has the above cited meaning, to form 5-hydroxypyrazoles of formula (I).

    摘要翻译： 本发明涉及制备式（I）的1-取代的5-羟基吡唑的方法，其中R1是C1-C6-烷基，C2-C6-烯基，C2-C6-炔基，C3-C6-环烷基或C1- C4烷氧基，其中这些基团可以被卤素，C 1 -C 4 - 烷氧基，苯氧基，C 1 -C 6 - 烷氧基羰基，C 1 -C 6烷硫基羰基或具有3-14个环原子的环状体系取代，通过使a）烷基乙烯基醚 （IVa），“二光气”（IVb）或“三光气”（IVc））中形成式（V）的酰氯的通式（III）的化合物，其中R2为C1-C6-烷基或C3-C6- b）通过将氯化氢除去相应的式（VI）的3-烷氧基丙烯酰氯，并且c）使所述酰氯与式（Ⅶ）的肼反应，其中R 1具有上述含义，形成5-羟基吡唑 的式（I）化合物。