公开(公告)号：US5961999A

公开(公告)日：1999-10-05

申请号：US123264

申请日：1998-07-28

申请人： Rudolf Bimczok ,  Guenther Lang

发明人： Rudolf Bimczok ,  Guenther Lang

IPC分类号： A61K7/00

CPC分类号： Y10S514/828 ,  Y10S514/844 ,  Y10S514/846 ,  Y10S514/847

摘要： The method of skin care includes applying a skin care preparation to the skin of an individual in an amount sufficient to moisturize the skin or to cause a reduction of skin wrinkling and a smoothing of the skin. The skin care preparation has a pH value of 1 to 7 and contains from 0.1 to 20 percent by weight of at least one betaine ester of formula (I)R.sub.1 --O--CO--CH.sub.2 --N.sup.+ (CH.sub.3).sub.3 A.sup.-(I),wherein R.sub.1 is a branched or straight chain alkyl group having from 10 to 30 carbon atoms and A- is a cosmetically acceptable anion; andfrom 0.05 to 20 percent by weight of at least one .alpha.-hydroxy acid present as a free acid, or in a lactone form thereof, or as a skin-compatible salt thereof with an organic base or an inorganic alkali, and/or as stereoisomers thereof, as D, L, and/or DL form. The at least one .alpha.-hydroxy acid is selected from the group consisting of alkyl .alpha.-hydroxy acids, aralkyl .alpha.-hydroxy acids, aryl .alpha.-hydroxy acids, polyhydroxy .alpha.-hydroxy acids and polycarboxylic .alpha.-hydroxy acids represented by the following chemical structure: ##STR1## wherein Ra and Rb represent, independently of each other, H, F, Cl, Br, an aryl group, an aralkyl group made from an aryl group and an alkyl radical having 1 to 25 carbon atoms, a saturated or unsaturated, straight or branched chain alkyl group having 1 to 25 carbon atoms, a cyclic group having 5 or 6 members including carbon atoms, with the proviso that Ra and Rb are not the same, and the aryl, arylalkyl and alkyl groups may have at least one substituent selected from the group consisting of OH, CHO, COOH and alkoxy groups having from 1 to 9 carbon atoms.

摘要翻译： 皮肤护理方法包括将皮肤护理制剂以足以滋润皮肤或减少皮肤皱纹和使皮肤光滑的方式对个体皮肤施用。 皮肤护理制剂的pH值为1〜7，含有0.1〜20重量％的式（I）R1-O-CO-CH2-N +（CH3）3A-（Ⅰ）的至少一种甜菜碱酯， 其中R1是具有10-30个碳原子的支链或直链烷基，A-是化妆品可接受的阴离子; 和0.05至20重量％的至少一种作为游离酸存在的α-羟基酸，或以其内酯形式存在，或作为其与有机碱或无机碱的皮肤相容的盐，和/或 其立体异构体，如D，L和/或DL形式。 所述至少一种α-羟基酸选自由以下化学结构表示的α-烷基α-羟基酸，芳烷基α-羟基酸，芳基α-羟基酸，多羟基α-羟基酸和多元羧酸α-羟基酸 其中R a和R b彼此独立地表示H，F，Cl，Br，芳基，由芳基和具有1至25个碳原子的烷基构成的芳烷基，饱和或不饱和的直链或 具有1至25个碳原子的支链烷基，具有5或6个碳原子的环状基团，条件是Ra和Rb不相同，芳基，芳基烷基和烷基可以具有至少一个取代基 由OH，CHO，COOH和具有1至9个碳原子的烷氧基组成的组。

公开(公告)号：US4603048A

公开(公告)日：1986-07-29

申请号：US431573

申请日：1982-09-30

申请人： Eugen Konrad ,  Guenther Lang

发明人： Eugen Konrad ,  Guenther Lang

IPC分类号： C11D3/37 ,  A61K8/00 ,  A61K8/34 ,  A61K8/36 ,  A61K8/39 ,  A61K8/46 ,  A61K8/73 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/06 ,  C08B37/08 ,  A61K7/06 ,  A61K7/09

CPC分类号： A61K8/39 ,  A61K8/736 ,  A61Q5/02 ,  A61Q5/06 ,  C08B37/003

摘要： Acid aqueous or aqueous-alcoholic solutions of a salt of chitosan, in which the anion of the salt is a tenside-anion of the general formula I[R--X--(CH.sub.2 CH.sub.2 O).sub.n --Y].sup..crclbar. (I)with R being C.sub.8 -C.sub.30 -alkyl or C.sub.8 -C.sub.30 -alkylene, X is O, COO, CONR' (R' is H, C.sub.1 -C.sub.4 -alkyl or C.sub.1 -C.sub.4 -hydroxyalkyl), phenoxy, n is 1 to 100, and Y is (CH.sub.2).sub.m COO.sup..crclbar. (m is 1 to 4) or SO.sub.3.sup..crclbar., as well as cosmetic preparations with a content of these solutions. The chitosan salt solutions are obtained by dissolving chitosan in an aqueous or aqueous-alcoholic solution containing, relative to the free amino groups of the chitosan, an about equimolar amount of a tenside of the formula IIR--X--(CH.sub.2 CH.sub.2 O).sub.n --Y--H (II)in which R, X, n and Y have the above-given meanings. The chitosan salts contained in the solutions possess good film-forming characteristics of known chitosan salts, but in the presence of anionic tenside form no insoluble chitosan salts. The solutions can therefore be used as skin care, hair conditioning or hair strengthening component in cosmetic preparations, particularly also in shampoos on the basis of anionic tensides.

摘要翻译： 壳聚糖盐的酸性水溶液或含水溶液，其中盐的阴离子是通式I [RX-（CH 2 CH 2 O）n Y]（ - ）（I）的表面活性剂，R为C8-C30 - 烷基或C 8 -C 30亚烷基，X是O，COO，CONR'（R'是H，C 1 -C 4 - 烷基或C 1 -C 4 - 羟烷基），苯氧基，n是1至100，Y是（CH 2） mOO（ - ）（m为1至4）或SO3（ - ），以及具有这些溶液含量的化妆品制剂。 壳聚糖盐溶液是通过将壳聚糖溶解在含有相对于脱乙酰壳多糖游离氨基的水溶液或含水醇溶液中得到约等摩尔量式II RX-（CH 2 CH 2 O）n YH（II）表面活性剂在 其中R，X，n和Y具有上述含义。 包含在溶液中的壳聚糖盐具有已知的壳聚糖盐的良好的成膜特性，但是在阴离子表面活性剂存在下，不形成不溶性壳聚糖盐。 因此，溶液可以用作化妆品制剂中的护肤品，头发调理剂或头发强化组分，特别是在阴离子表面活性剂的基础上用于洗发剂。

公开(公告)号：US6153178A

公开(公告)日：2000-11-28

申请号：US981367

申请日：1997-12-19

申请人： Guenther Lang ,  Beate Dannecker ,  Wolfgang Hanefeld ,  Heiko Walther

发明人： Guenther Lang ,  Beate Dannecker ,  Wolfgang Hanefeld ,  Heiko Walther

IPC分类号： A61K8/00 ,  A61K8/46 ,  A61K8/49 ,  A61Q5/04 ,  C07D295/088 ,  C07D295/185 ,  A61K7/09 ,  A61K7/11 ,  A61K7/13

CPC分类号： A61Q5/04 ,  A61K8/4913 ,  A61K8/4926 ,  C07D295/185

摘要： The aqueous composition for permanent hair-styling has a pH of from 6.5 to 9.5 and contains from 3 to 28% by weight of a compound of formula I, ##STR1## wherein A represents --CH.sub.2 --, --C.dbd.O--, --S--, --O-- and --NR-- and R is an alkyl group having from 1 to 6 carbon atoms or a hydroxyalkyl group having from 1 to 6 carbon atoms, m is an integer from 1 to 3 and n is an integer from 0 to 3, with the proviso that n=0 only when A is methylene; water and one or more cosmetic additive ingredient selected from the group consisting of thickening agents, anionic surfactants, cationic surfactants, amphoteric surfactants, nonionic surfactants, opacifiers, alcohols, sugars, solubilizers, stabilizers, buffer substances, perfume oils, colorants, hair conditioning and hair treatment ingredients.

摘要翻译： PCT No.PCT / EP97 / 01028 Sec。 371 1997年12月19日第 102（e）1997年12月19日PCT PCT 1997年3月1日PCT公布。 公开号WO97 / 41828 日期1997年11月13日永久性发型用水性组合物的pH为6.5〜9.5，含有3〜28重量％的式I化合物，其中A表示-CH 2 - ， - C = O-， -S-，-O-和-NR-，R为具有1至6个碳原子的烷基或具有1至6个碳原子的羟烷基，m为1至3的整数，n为 0至3，条件是仅当A为亚甲基时n = 0; 水和一种或多种选自增稠剂，阴离子表面活性剂，阳离子表面活性剂，两性表面活性剂，非离子表面活性剂，遮光剂，醇，糖，增溶剂，稳定剂，缓冲物质，香料油，着色剂，头发调理剂和 头发处理成分。

公开(公告)号：US06482808B1

公开(公告)日：2002-11-19

申请号：US09700871

申请日：2001-01-23

申请人： Christian Springob ,  Manuela Javet ,  Ursula Hehner ,  Thomas Kripp ,  Beate Grasser ,  Kirstin Uhl ,  Guenther Lang

发明人： Christian Springob ,  Manuela Javet ,  Ursula Hehner ,  Thomas Kripp ,  Beate Grasser ,  Kirstin Uhl ,  Guenther Lang

IPC分类号： A01N5700

CPC分类号： A61K8/676 ,  A61Q5/00

摘要： The composition for hardening, strengthening and restructuring keratin-containing materials and/or for increasing the volume of keratin-containing fibers, such as hair, contains from 0.3 to 50.0% by weight of one or more reductones, each having a —(HO)C═C(OH)— group. The reductone ingredient is preferably ascorbic or isoascorbic acid, a salt of ascorbic or isoascorbic acid, such as an alkali metal or alkaline earth metal salt, an ester of ascorbic or isoascorbic acid, 6-O-palmitoyl ascorbate, ascorbyl phosphate, 2,3-dihydroxy-2-propenal and hydroxypropanedial. A method of treating keratin-containing materials or fibers to harden, strengthen and restructure keratin-containing materials and/or to increase the volume of the keratin-containing fibers by applying this composition and allowing it to act is described. A method of pre-treating keratin-containing material that is to be subjected to a chemical or physical treatment, such as dyeing or permanent shaping is also described.

摘要翻译： 用于硬化，强化和重组含角蛋白的材料和/或用于增加含角蛋白的纤维如毛发的体积的组合物含有0.3至50.0重量％的一种或多种还原剂，每种还原剂具有 - （HO） C = C（OH） - 基。 还原酮成分优选为抗坏血酸或异抗坏血酸，抗坏血酸或异抗坏血酸的盐，例如碱金属或碱土金属盐，抗坏血酸或异抗坏血酸的酯，6-O-棕榈酰抗坏血酸，抗坏血酸磷酸2,3 - 二羟基-2-丙醛和羟基丙二醛。 描述了通过应用该组合物并使其起作用来治疗含角蛋白的材料或纤维来硬化，加强和重组含角蛋白的材料和/或增加含角蛋白的纤维的体积的方法。 还描述了预处理待进行化学或物理处理的含角蛋白的材料如染色或永久成形的方法。

公开(公告)号：US6153196A

公开(公告)日：2000-11-28

申请号：US68419

申请日：1998-05-13

申请人： Thomas Kripp ,  Beate Krause ,  Guenther Lang ,  Wolfgang Maurer ,  Ingrid Toeche-Mittler

发明人： Thomas Kripp ,  Beate Krause ,  Guenther Lang ,  Wolfgang Maurer ,  Ingrid Toeche-Mittler

IPC分类号： A61K8/00 ,  A61K8/92 ,  A61K8/97 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/06 ,  A61Q5/12 ,  A61Q17/04 ,  A61Q19/00 ,  A61K35/78

CPC分类号： A61Q19/00 ,  A61K8/922 ,  A61Q5/02 ,  A61Q5/06 ,  A61Q5/12 ,  A61Q17/04

摘要： The use of flower wax, preferably from flowers of the jasmine, the mimosa, the narcissus, the bitter orange or the wild camomile in liquid hair treatment agents, as well as liquid hair treatment agents containing flower wax.

摘要翻译： PCT No.PCT / EP97 / 05459 Sec。 371日期1998年5月13日 102（e）日期1998年5月13日PCT提交1997年10月4日PCT公布。 公开号WO98 / 16188 日期1998年4月23日使用花蜡，优选来自茉莉花，含羞草，水仙，苦橙或野生甘菊的液体毛发处理剂，以及含有花蜡的液体毛发处理剂。

公开(公告)号：US20050226838A1

公开(公告)日：2005-10-13

申请号：US11100225

申请日：2005-04-06

申请人： Thomas Krause ,  Jan Baumeister ,  Dirk Weber ,  Guenther Lang ,  Angelika Beyer ,  Ellen Florig ,  Klaus Gaenger ,  Hartmut Schiemann

发明人： Thomas Krause ,  Jan Baumeister ,  Dirk Weber ,  Guenther Lang ,  Angelika Beyer ,  Ellen Florig ,  Klaus Gaenger ,  Hartmut Schiemann

IPC分类号： A61K8/73 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/06 ,  A61Q5/12 ,  A61K7/06 ,  A61K7/11

CPC分类号： A61K8/736 ,  A61Q5/02 ,  A61Q5/06 ,  A61Q5/065 ,  A61Q5/10 ,  A61Q5/12

摘要： The hair treatment composition contains preferably from 0.01 to 20 percent by weight of at least one N-hydroxyalkyl-O-benzyl chitosan and from 0.01 to 20 percent by weight of at least one other hair treatment effective ingredient. The at least one N-hydroxyalkyl-O-benzyl chitosan has at least one hydroxylalkyl group, preferably a hydroxyethyl, hydroxypropyl or hydroxybutyl group, and has from 2 to 20 carbon atoms. Various methods of treating hair with hair treatment compositions containing one or more of the N-hydroxyalkyl-O-benzyl chitosans are described.

摘要翻译： 头发处理组合物优选含有0.01至20重量％的至少一种N-羟烷基-O-苄基壳聚糖和0.01至20重量％的至少一种其它头发处理有效成分。 至少一种N-羟基烷基-O-苄基壳聚糖具有至少一个羟基烷基，优选羟乙基，羟丙基或羟基丁基，并且具有2至20个碳原子。 描述了含有一种或多种N-羟烷基-O-苄基壳聚糖的头发处理组合物处理毛发的各种方法。

公开(公告)号：US5637295A

公开(公告)日：1997-06-10

申请号：US559375

申请日：1995-11-16

申请人： Guenther Lang ,  Kirstin Uhl ,  Gerhard Sendelbach ,  Gerhard Maresch

发明人： Guenther Lang ,  Kirstin Uhl ,  Gerhard Sendelbach ,  Gerhard Maresch

IPC分类号： A61K8/895 ,  A61K8/898 ,  A61Q5/04 ,  A61K7/09

CPC分类号： A61Q5/04 ,  A61K8/898

摘要： The permanent shaping composition for permanent shaping of hair includes from 2 to 25 percent by weight of a conventional keratin-reducing compound and from 0.02 to 5 percent by weight of certain diquaternary polysiloxanes. The permanent wave-pretreatment composition includes from 0.02 to 5 percent by weight of the diquaternary polysiloxanes. The permanent shaping composition advantageously includes mercaptocarbonic acid reducing agents and has a pH of from 6 to 10 and may include conventional cosmetic additives. Methods for using the permanent shaping composition and the permanent wave-pretreatment composition are described which provide a more uniform permanant wave from the hair roots to the hair tips.

摘要翻译： 用于永久成型头发的永久性成形组合物包含2至25重量％的常规角蛋白减少化合物和0.02至5重量％的某些二季聚硅氧烷。 永久波浪预处理组合物包含0.02至5重量％的二季聚硅氧烷。 永久性成形组合物有利地包括巯基碳酸还原剂，并且pH为6至10，并且可以包括常规的化妆品添加剂。 描述了使用永久成形组合物和永久性波浪预处理组合物的方法，其提供从发根到毛发尖端的更均匀的永久波。

公开(公告)号：US5503826A

公开(公告)日：1996-04-02

申请号：US330363

申请日：1994-10-27

申请人： Guenther Lang ,  Hans-Juergen Braun ,  Gerhard Maresch

发明人： Guenther Lang ,  Hans-Juergen Braun ,  Gerhard Maresch

IPC分类号： A61K8/00 ,  A61K8/44 ,  A61Q5/04 ,  C07C323/58 ,  A61K7/09 ,  A61K7/06

CPC分类号： A61Q5/04 ,  A61K8/447 ,  C07C323/58

摘要： The new keratin-reducing substances useful in compositions for permanent shaping of hair are glyceryl esters of cysteine, especially the monoglyceryl esters. As monoglyceryl esters of cysteine 2-amino-3-mercaptopropionic acid-(2',3'-dihydroxypropyl)ester and 2-amino-3-mercaptopropionic acid-(1',3'-dihydroxyisopropyl)ester are particularly preferred. A preferred embodiment of the compositions for permanent shaping of hair consists of a ready-to-use mixture of a water-free component including at least one glyceryl ester of cysteine and at least one other component which is kept physically separately from the water-free component until the mixture is prepared. The compositions also can include other conventional ingredients normally used in permanent shaping compositions such as surfactants and thickeners. The compositions have a preferred pH range of 6.0 to 8.5 and contain from 8 to 28 percent by weight of the glyceryl esters of cysteine.

摘要翻译： 用于头发永久成型的组合物中的新的角蛋白还原物质是半胱氨酸的甘油酯，特别是单甘油酯。 作为半胱氨酸2-甘氨酸酯，2-氨基-3-巯基丙酸 - （2'，3'-二羟基丙基）酯和2-氨基-3-巯基丙酸 - （1'，3'-二羟基异丙基）酯是特别优选的。 用于永久成型头发的组合物的优选实施方案是由包含至少一种半胱氨酸甘油酯和至少一种其它成分的无水组分的即用混合物组成的物质与水分离物质分开 组分直到制备混合物。 组合物还可以包括通常用于永久成型组合物如表面活性剂和增稠剂的其它常规成分。 组合物具有6.0至8.5的优选pH范围并且含有8至28重量％的半胱氨酸的甘油酯。

公开(公告)号：US07341715B2

公开(公告)日：2008-03-11

申请号：US09979965

申请日：2001-05-21

申请人： Beate Dannecker ,  Ursus Schweizer ,  Guenther Lang ,  Regina Ortmann ,  Wolfgang Hanefeld

发明人： Beate Dannecker ,  Ursus Schweizer ,  Guenther Lang ,  Regina Ortmann ,  Wolfgang Hanefeld

IPC分类号： A61Q5/04 ,  C07D295/22 ,  C07D307/02 ,  C07D211/20 ,  C07D211/30

CPC分类号： A61Q5/04 ,  A61K8/447 ,  A61K8/46

摘要： The preparation for permanently deforming hair has a pH of 6.5 to 9.5 and contains, as keratin-reducing agent, a 2-mercaptopropion-amide of the formula (I): in which R1 and R2, independently of one another, represent H, a linear or branched alkylaminoalkyl group with 2 to 8 carbon atoms, or a morpholinoalkyl group with 2 to 3 carbon atoms in the alkyl portion of the morpholinoalkyl group, with the proviso that R1 and R2 are not simultaneously H, or that R1 and R2, together with the nitrogen atom, form a five-or six-membered heterocyclic ring, which optionally contain an additional N or O and are optionally substituted with one or two OH and/or methyl groups.

摘要翻译： 用于永久变形毛发的制剂的pH为6.5至9.5，并且作为角蛋白还原剂包含式（I）的2-巯基丙酰胺：其中R 1和R 2 > 2 <！ - SIPO - >彼此独立地表示H，具有2至8个碳原子的直链或支链烷基氨基烷基或在吗啉代烷基的烷基部分具有2至3个碳原子的吗啉代烷基，条件是 R 1和R 2不是同时为H，或者R 1和R 2，以及R 1和R 2 氮原子形成五元或六元杂环，其任选地含有另外的N或O，并且任选被一个或两个OH和/或甲基取代。

公开(公告)号：US06399051B2

公开(公告)日：2002-06-04

申请号：US09269901

申请日：1999-06-08

申请人： Beate Dannecker ,  Guenther Lang ,  Wolfgang Hanefeld ,  Heiko Walther

发明人： Beate Dannecker ,  Guenther Lang ,  Wolfgang Hanefeld ,  Heiko Walther

IPC分类号： A61K709

CPC分类号： A61Q5/04 ,  A61K8/46 ,  C07C323/60

摘要： The present invention relates to a composition and method for permanently shaping hair, in which an N,N-disubstituted mercaptoacetamide of the formula I: or a salt thereof, wherein R1 and R2 are each independently selected from the group consisting of straight-chain alkyl groups having 1 to 6 carbon atoms, branched-chain alkyl groups having 1 to 6 carbon atoms, monohydroxyalkyl groups having 1 to 6 carbon atoms, polyhydroxyalkyl groups having 1 to 6 carbon atoms and carboxyalkyl groups having 1 to 6 carbon atoms, is employed as keratin reducing agent. A process for making these mercaptoacetamides is also described as well as a novel mercaptoacetamide, N-ethyl-2′-hydroxyethyl-mercaptoacetamide. The mercaptoacetamides provide gentle and uniform shaping of hair in a pH range of 4.5 to 9.5 and do not cause allergic or sensitizing reactions.

摘要翻译： 本发明涉及用于永久形成头发的组合物和方法，其中式I的N，N-二取代的巯基乙酰胺或其盐，其中R 1和R 2各自独立地选自直链烷基 使用具有1至6个碳原子的基团，具有1至6个碳原子的支链烷基，具有1至6个碳原子的单羟基烷基，具有1至6个碳原子的多羟基烷基和具有1至6个碳原子的羧基烷基作为 角蛋白还原剂。 还描述了制备这些巯基乙酰胺的方法以及新的巯基乙酰胺，N-乙基-2'-羟乙基 - 巯基乙酰胺。 巯基乙酰胺在4.5至9.5的pH范围内提供温和均匀的头发成型，并且不引起过敏或致敏反应。