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公开(公告)号：US08189975B2
公开(公告)日：2012-05-29
申请号：US12573278
申请日：2009-10-05
IPC分类号： G02B6/06
CPC分类号： G01N21/65 , G01J3/02 , G01J3/0218 , G01J3/0291 , G01J3/44 , G01N21/6458 , G01N2021/6417 , G01N2021/6484 , G02B21/16 , Y10T436/112499
摘要： A fiber spectroscopic probe that can be mounted directly above the objective lens of a standard microscope to add a spectroscopic function to the microscope. The fiber spectroscopic probe only consists of a minimum number of optical components and is compact enough to induce minimum alteration to the optical path of the microscope.
摘要翻译： 一种可以直接安装在标准显微镜物镜正上方的光纤光谱探头，为显微镜增加光谱功能。 光纤光谱探头仅由最少数量的光学元件组成，并且足够紧凑，可以对显微镜的光路产生最小的改变。
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公开(公告)号：US20110081110A1
公开(公告)日：2011-04-07
申请号：US12573278
申请日：2009-10-05
IPC分类号： G02B6/26
CPC分类号： G01N21/65 , G01J3/02 , G01J3/0218 , G01J3/0291 , G01J3/44 , G01N21/6458 , G01N2021/6417 , G01N2021/6484 , G02B21/16 , Y10T436/112499
摘要： A fiber spectroscopic probe that can be mounted directly above the objective lens of a standard microscope to add a spectroscopic function to the microscope. The fiber spectroscopic probe only consists of a minimum number of optical components and is compact enough to induce minimum alteration to the optical path of the microscope.
摘要翻译： 一种可以直接安装在标准显微镜物镜正上方的光纤光谱探头，为显微镜增加光谱功能。 光纤光谱探头仅由最少数量的光学元件组成，并且足够紧凑，可以对显微镜的光路产生最小的改变。
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公开(公告)号：US08135249B2
公开(公告)日：2012-03-13
申请号：US12611138
申请日：2009-11-03
CPC分类号： G01N21/6458 , G01J3/02 , G01J3/0218 , G01J3/0291 , G01J3/44 , G01N21/65 , G01N2021/6417 , G01N2021/6484 , G02B21/16
摘要： A fiber spectroscopic probe that can be mounted directly above the objective lens of a standard microscope to add a spectroscopic function to the microscope. The constructed microscope with fiber spectroscopic probe is suitable for micro-sampling, Raman analysis, as well as fluorescence analysis and can be easily reconfigured for different excitation/detection wavelengths. The fiber spectroscopic probe only consists of a minimum number of optical components and is compact enough to induce minimum alteration to the optical path of the microscope.
摘要翻译： 一种可以直接安装在标准显微镜物镜正上方的光纤光谱探头，为显微镜增加光谱功能。 具有光纤光谱探头的构建显微镜适用于微量采样，拉曼分析以及荧光分析，可以轻松重新配置不同的激发/检测波长。 光纤光谱探头仅由最少数量的光学元件组成，并且足够紧凑，可以对显微镜的光路产生最小的改变。
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公开(公告)号：US09958395B2
公开(公告)日：2018-05-01
申请号：US15424931
申请日：2017-02-06
申请人： Xin Jack Zhou , Sean Xiaolu Wang , Qun Li
发明人： Xin Jack Zhou , Sean Xiaolu Wang , Qun Li
CPC分类号： G01N21/718 , G01J3/443 , G01N33/20 , H01S5/0615
摘要： This invention discloses an improved laser induced breakdown spectroscopy (LIBS) apparatus and method for the detection of mineral and metal contamination in liquid samples. The mineral and metal contaminant is first collected by filtering the liquid sample with a membrane filter. The membrane filter with the mineral and metal contaminant is then measured by a LIBS apparatus. The LIBS apparatus is based on a high repetition rate pulsed laser. The laser produces a train of laser pulses at a high repetition rate in the kHz (or even higher) range. When the laser beam hits the surface of the membrane filter, it generates several thousands of micro-plasma emissions per second. Synchronized miniature CCD array optical spectrometer modules collect the LIBS signal from these micro-plasma emissions. By adjusting the integration time of the spectrometer to cover a plurality of periods of the laser pulse train, the spectrometer integrates the LIBS signal produced by this plurality of laser pulses. Hence the intensity of the obtained LIBS spectrum can be greatly improved to increase the signal-to-noise ratio (SNR) and lower the level of detection (LOD).
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公开(公告)号：US20170234800A1
公开(公告)日：2017-08-17
申请号：US15424931
申请日：2017-02-06
申请人： Xin Jack Zhou , Sean Xiaolu Wang , Qun Li
发明人： Xin Jack Zhou , Sean Xiaolu Wang , Qun Li
CPC分类号： G01N21/718 , G01J3/443 , G01N33/20 , H01S5/0615
摘要： This invention discloses an improved laser induced breakdown spectroscopy (LIBS) apparatus and method for the detection of mineral and metal contamination in liquid samples. The mineral and metal contaminant is first collected by filtering the liquid sample with a membrane filter. The membrane filter with the mineral and metal contaminant is then measured by a LIBS apparatus. The LIBS apparatus is based on a high repetition rate pulsed laser. The laser produces a train of laser pulses at a high repetition rate in the kHz (or even higher) range. When the laser beam hits the surface of the membrane filter, it generates several thousands of micro-plasma emissions per second. Synchronized miniature CCD array optical spectrometer modules collect the LIBS signal from these micro-plasma emissions. By adjusting the integration time of the spectrometer to cover a plurality of periods of the laser pulse train, the spectrometer integrates the LIBS signal produced by this plurality of laser pulses. Hence the intensity of the obtained LIBS spectrum can be greatly improved to increase the signal-to-noise ratio (SNR) and lower the level of detection (LOD).
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公开(公告)号：US08699020B1
公开(公告)日：2014-04-15
申请号：US13711668
申请日：2012-12-12
申请人： Xin Jack Zhou , Daoguo Jiang , Sean Xiaolu Wang
发明人： Xin Jack Zhou , Daoguo Jiang , Sean Xiaolu Wang
IPC分类号： G01J3/44
CPC分类号： G01J3/44 , G01J3/0264 , G01J3/0272 , G01N21/65 , G01N2201/0221
摘要： This invention discloses a handheld Raman spectrometer. The handheld Raman spectrometer comprises: (i) a handheld enclosure; (ii) a volume Bragg grating stabilized laser mounted in the handheld enclosure for producing laser light; (iii) a Raman probe for delivering the laser light to a subject to produce Raman scattered light from the subject and collecting the Raman scattered light; (iv) a spectrometer mounted in the handheld enclosure for measuring the Raman scattered light and obtaining a Raman spectrum; (v) a high brightness display mounted in the handheld enclosure for displaying the obtained Raman spectrum; (vi) a multi-touch screen mounted on top of the high brightness display for receiving user inputs; (vii) a central processing unit mounted in the handheld enclosure for processing user inputs and controlling operation of the handheld Raman spectrometer; and (viii) a user interface based on the high brightness display, the multi-touch screen, and the central processing unit, the user interface is programmed to be capable to respond to user inputs incurring at least two points of contact with the multi-touch screen.
摘要翻译： 本发明公开了一种手持拉曼光谱仪。 手持拉曼光谱仪包括：（i）手持式外壳; （ii）安装在手持式外壳中用于产生激光的体积布拉格光栅稳定激光; （iii）拉曼探头，用于将激光发射到被摄体以产生来自被摄体的拉曼散射光并收集拉曼散射光; （iv）安装在手持式外壳中用于测量拉曼散射光并获得拉曼光谱的光谱仪; （v）安装在手持式外壳中的高亮度显示器，用于显示所获得的拉曼光谱; （vi）安装在高亮度显示器顶部的用于接收用户输入的多点触摸屏; （vii）安装在手持式外壳中的中央处理单元，用于处理用户输入并控制手持拉曼光谱仪的操作; 和（viii）基于高亮度显示器，多点触摸屏幕和中央处理单元的用户界面，用户界面被编程为能够响应于与多重触摸屏幕的至少两个接触点的用户输入， 触摸屏。
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公开(公告)号：USD677185S1
公开(公告)日：2013-03-05
申请号：US29408648
申请日：2011-12-15
申请人： Xin Jack Zhou , Daoguo Jiang , Jun Xu , Yuejin Xu , Sean Xiaolu Wang
设计人： Xin Jack Zhou , Daoguo Jiang , Jun Xu , Yuejin Xu , Sean Xiaolu Wang
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公开(公告)号：US20180372540A1
公开(公告)日：2018-12-27
申请号：US16053892
申请日：2018-08-03
申请人： Jun Zhao , Xin Jack Zhou , Sean Xiaolu Wang
发明人： Jun Zhao , Xin Jack Zhou , Sean Xiaolu Wang
摘要： This invention relates to a light delivery and collection device for performing spectroscopic analysis of a subject. The light delivery and collection device comprises a reflective cavity with two apertures. The first aperture receives excitation light which then diverges and projects onto the second aperture. The second aperture is applied to the subject such that the reflective cavity substantially forms an enclosure covering an area of the subject. The excitation light interacts with the covered area of the subject to produce inelastic scattering and/or fluorescence emission from the subject. The reflective cavity reflects the excitation light as well as the inelastic scattering and/or fluorescence emission that is reflected and/or back-scattered from the subject and redirects it towards the subject. This causes more excitation light to penetrate into the subject hence enabling sub-surface measurement and also improves the collection efficiency of the inelastic scattering or fluorescence emission. The shape of the reflective cavity is optimized to further improve the collection efficiency.
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公开(公告)号：US10119917B2
公开(公告)日：2018-11-06
申请号：US15653636
申请日：2017-07-19
申请人： Jun Zhao , Xin Jack Zhou , Sean Xiaolu Wang
发明人： Jun Zhao , Xin Jack Zhou , Sean Xiaolu Wang
摘要： This invention relates to an apparatus and method for performing bidirectional Raman spectroscopy of a sample, preferably a diffusely scattering sample, in which two excitation light sources are employed to illuminate the sample from two opposite directions to excite Raman scattering signal from the sample. The Raman scattering signal which transmits through the sample are collected by two optical devices each positioned on the opposite side of the sample to obtain two transmission Raman spectra of the sample, which enables the accurate determination of the composition of the whole sample.
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公开(公告)号：US09766182B2
公开(公告)日：2017-09-19
申请号：US14708638
申请日：2015-05-11
申请人： Xin Jack Zhou , Sean Xiaolu Wang , Qun Li
发明人： Xin Jack Zhou , Sean Xiaolu Wang , Qun Li
CPC分类号： G01N21/718 , G01J3/443
摘要： This invention discloses a compact laser induced breakdown spectroscopy (LIBS) apparatus suitable for field operations. The LIBS apparatus comprises a Q-switched laser with laser pulse energy between several tens and several thousands of micro joules (μJ), which is significantly lower than that of traditional LIBS lasers. The spectrograph of the LIBS apparatus employs a dual CCD (charge coupled device) design, which maintains compact size and in the meantime offers large spectral coverage and high spectral resolution.
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