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公开(公告)号：US20100143878A1
公开(公告)日：2010-06-10
申请号：US12444075
申请日：2007-10-08
申请人： Ryan J. Olson , Rex M. Bitner , Allan M. Tereba , Laura L. Bozek
发明人： Ryan J. Olson , Rex M. Bitner , Allan M. Tereba , Laura L. Bozek
CPC分类号： C12N5/0612 , C12N1/06 , C12N5/061 , C12N15/1013
摘要： Disclosed are methods for differential extraction of a target component from a sample which is predominantly composed of other types of non-target cells that can be lysed using methods that do not lyse the target cells, so that the target material can be purified away from the lysed non-target material. One exemplary method is directed to isolating sperm cells from an aqueous sample and kits for performing same.
摘要翻译： 公开了从主要由其他类型的非靶细胞组成的样品中差异提取靶组分的方法，所述其他类型的非靶细胞可以使用不裂解靶细胞的方法裂解，从而可以将目标物质从 裂解的非目标材料。 一个示例性的方法是将精子细胞与含水样品分离，并进行相同的试剂盒。
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公开(公告)号：US07090975B2
公开(公告)日：2006-08-15
申请号：US09924981
申请日：2001-08-07
申请人： John W. Shultz , Ryan J. Olson , Christine Andrews
发明人： John W. Shultz , Ryan J. Olson , Christine Andrews
CPC分类号： C12Q1/6827 , C12Q1/04 , C12Q1/66 , C12Q1/6818 , Y10T436/24 , C12Q2535/125 , C12Q2565/301 , C12Q2537/162 , C12Q2521/101 , C12Q2565/101
摘要： Processes are disclosed using the depolymerization of a nucleic acid hybrid and incorporation of a suitable nucleotide to qualitatively and quantitatively analyze for the presence of predetermined nucleic acid target sequences. Applications of those processes include the detection of single nucleotide polymorphisms, identification of single base changes, genotyping, medical marker diagnostics, mirosequencing, and.
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公开(公告)号：US10032311B1
公开(公告)日：2018-07-24
申请号：US14499907
申请日：2014-09-29
申请人： Max G. Taylor , Scott E. Schultz , Matthew J. Cunnien , Michael J. Armstrong , Ryan J. Olson , Peter J. Flugstad , Shawn M. Spencer
发明人： Max G. Taylor , Scott E. Schultz , Matthew J. Cunnien , Michael J. Armstrong , Ryan J. Olson , Peter J. Flugstad , Shawn M. Spencer
摘要： Present novel and non-trivial system, device, and method for enhancing a three-dimensional synthetic image are disclosed. The image generating system is comprised of a first image data source, a second image data source, an image processing unit (“IPU”), and a display system. The IPU may be configured to receive first image data of a first image of a first external scene produced from object data; receive second image data of a second image of a second external scene produced from point cloud data acquired by one or more image capturing devices or object data augmented with point cloud data; combine the first image data with the second image data to produce third image data of a third image of the first external scene; and provide the third image data set to the display system. Fourth image data could be received and included in the production of the three image data.
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公开(公告)号：US06270974B1
公开(公告)日：2001-08-07
申请号：US09406147
申请日：1999-09-27
申请人： John William Shultz , Martin K. Lewis , Donna Leippe , Michelle Mandrekar , Daniel Kephart , Richard Byron Rhodes , Christine Ann Andrews , James Robert Hartnett , Trent Gu , Ryan J. Olson , Keith V. Wood , Roy Welch
发明人： John William Shultz , Martin K. Lewis , Donna Leippe , Michelle Mandrekar , Daniel Kephart , Richard Byron Rhodes , Christine Ann Andrews , James Robert Hartnett , Trent Gu , Ryan J. Olson , Keith V. Wood , Roy Welch
IPC分类号： C12Q168
CPC分类号： C12Q1/689 , C12Q1/04 , C12Q1/66 , C12Q1/6823 , C12Q1/6827 , Y10T436/24 , C12Q2565/627 , C12Q2535/131 , C12Q2521/319 , C12Q2565/301 , C12Q2565/1015 , C12Q2537/101
摘要： Processes are disclosed using the depolymerization of a nucleic acid hybrid to qualitatively and quantitatively analyze for the presence of a predetermined exogenous nucleic acid. Applications of those processes include the detection of single nucleotide polymorphisms, identification of single base changes, determination of viral load, genotyping, medical marker diagnostics, and the like.
摘要翻译： 使用核酸杂交体的解聚来定性和定量分析预定的外源核酸的存在来公开方法。 这些过程的应用包括单核苷酸多态性的检测，单碱基变化的鉴定，病毒载量的确定，基因分型，医学标记诊断等。
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公开(公告)号：US06391551B1
公开(公告)日：2002-05-21
申请号：US09383316
申请日：1999-08-25
申请人： John William Shultz , Martin K. Lewis , Donna Leippe , Michelle Mandrekar , Daniel Kephart , Richard Byron Rhodes , Christine Ann Andrews , James Robert Hartnett , Trent Gu , Ryan J. Olson , Keith V. Wood , Roy Welch
发明人： John William Shultz , Martin K. Lewis , Donna Leippe , Michelle Mandrekar , Daniel Kephart , Richard Byron Rhodes , Christine Ann Andrews , James Robert Hartnett , Trent Gu , Ryan J. Olson , Keith V. Wood , Roy Welch
IPC分类号： C12Q168
CPC分类号： C12Q1/6823 , C12Q1/04 , C12Q1/66 , C12Q1/6827 , C12Q2535/131 , C12Q2521/319 , C12Q2565/301 , C12Q2565/1015 , C12Q2537/101 , C12Q2565/627
摘要： Processes are disclosed using the depolymerization of a nucleic acid hybrid to qualitatively and quantitatively analyze for the presence of a predetermined endogenous nucleic acid. Applications of those processes include the detection of single nucleotide polymorphisms, identification of single base changes, speciation, determination of viral load, genotyping, medical marker diagnostics, and the like.
摘要翻译： 公开了使用核酸杂交体的解聚定性和定量分析预定的内源性核酸的存在的方法。 这些过程的应用包括单核苷酸多态性的检测，单碱基变化的鉴定，物种形成，病毒载量的测定，基因分型，医学标记诊断等。
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公开(公告)号：US06730479B2
公开(公告)日：2004-05-04
申请号：US09790417
申请日：2001-02-22
申请人： John William Shultz , Martin K. Lewis , Donna Leippe , Michelle Mandrekar , Daniel Kephart , Richard Byron Rhodes , Christine Ann Andrews , James Robert Hartnett , Trent Gu , Ryan J. Olson , Keith V. Wood , Roy Welch
发明人： John William Shultz , Martin K. Lewis , Donna Leippe , Michelle Mandrekar , Daniel Kephart , Richard Byron Rhodes , Christine Ann Andrews , James Robert Hartnett , Trent Gu , Ryan J. Olson , Keith V. Wood , Roy Welch
IPC分类号： C12Q168
CPC分类号： C12Q1/6823 , C12Q1/04 , C12Q1/66 , C12Q1/68 , C12Q1/6827 , Y10T436/24 , C12Q2535/131 , C12Q2521/319 , C12Q2535/107 , C12Q2565/301 , C12Q2565/1015 , C12Q2537/101 , C12Q2565/627
摘要： Processes are disclosed using the depolymerization of a nucleic acid hybrid to qualitatively and quantitatively analyze for the presence of a predetermined nucleic acid. Applications of those processes include the detection of single nucleotide polymorphisms, identification of single base changes, speciation, determination of viral load, genotyping, medical marker diagnostics, and the like.
摘要翻译： 公开了使用核酸杂交体的解聚定性和定量分析预定核酸的存在的方法。 这些过程的应用包括单核苷酸多态性的检测，单碱基变化的鉴定，物种形成，病毒载量的测定，基因分型，医学标记诊断等。
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公开(公告)号：US06312902B1
公开(公告)日：2001-11-06
申请号：US09406065
申请日：1999-09-27
申请人： John William Shultz , Martin K. Lewis , Donna Leippe , Michelle Mandrekar , Daniel Kephart , Richard Byron Rhodes , Christine Ann Andrews , James Robert Hartnett , Trent Gu , Ryan J. Olson , Roy Welch
发明人： John William Shultz , Martin K. Lewis , Donna Leippe , Michelle Mandrekar , Daniel Kephart , Richard Byron Rhodes , Christine Ann Andrews , James Robert Hartnett , Trent Gu , Ryan J. Olson , Roy Welch
IPC分类号： C12Q168
CPC分类号： C12Q1/66 , C12Q1/04 , C12Q1/68 , C12Q1/6823 , C12Q1/6827 , Y10T436/24 , C12Q2565/301 , C12Q2565/1015 , C12Q2537/101 , C12Q2565/627 , C12Q2535/131 , C12Q2521/319 , C12Q2535/107
摘要： Processes are disclosed using the depolymerization of a nucleic acid hybrid to qualitatively and quantitatively analyze for the presence of a predetermined nucleic acid. Applications of those processes include the detection of single nucleotide polymorphisms, identification of single base changes, speciation, determination of viral load, genotyping, medical marker diagnostics, and the like.
摘要翻译： 公开了使用核酸杂交体的解聚定性和定量分析预定核酸的存在的方法。 这些过程的应用包括单核苷酸多态性的检测，单碱基变化的鉴定，物种形成，病毒载量的测定，基因分型，医学标记诊断等。
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公开(公告)号：US06235480B1
公开(公告)日：2001-05-22
申请号：US09358972
申请日：1999-07-21
申请人： John William Shultz , Martin K. Lewis , Donna Leippe , Michelle Mandrekar , Daniel Kephart , Richard Byron Rhodes , Christine Ann Andrews , James Robert Hartnett , Trent Gu , Ryan J. Olson , Keith V. Wood , Roy Welch
发明人： John William Shultz , Martin K. Lewis , Donna Leippe , Michelle Mandrekar , Daniel Kephart , Richard Byron Rhodes , Christine Ann Andrews , James Robert Hartnett , Trent Gu , Ryan J. Olson , Keith V. Wood , Roy Welch
IPC分类号： C12Q168
CPC分类号： C12Q1/6823 , C12Q1/04 , C12Q1/66 , C12Q1/68 , C12Q1/6827 , Y10T436/24 , C12Q2535/131 , C12Q2521/319 , C12Q2535/107 , C12Q2565/301 , C12Q2565/1015 , C12Q2537/101 , C12Q2565/627
摘要： Processes are disclosed using the depolymerization of a nucleic acid hybrid to qualitatively and quantitatively analyze for the presence of a predetermined nucleic acid. Applications of those processes include the detection of single nucleotide polymorphisms, identification of single base changes, speciation, determination of viral load, genotyping, medical marker diagnostics, and the like.
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