公开(公告)号：US20250108367A1

公开(公告)日：2025-04-03

申请号：US18832199

申请日：2023-01-25

Applicant: S.D. SIGHT DIAGNOSTICS LTD.

Inventor： Sharon PECKER ,  Noam MORALI ,  Aviram STEINBOK ,  Yochay Shlomo ESHEL ,  Trevor RUGGIERO ,  Kristofer KURTIN ,  Joseph Joel POLLAK ,  Daniel LEVNER ,  Julie RICHARDSON

IPC: B01L3/00

Abstract: Apparatus and methods are described for analyzing a bodily sample. A sample carrier (22), which houses the bodily sample, includes at least one fluidic channel (120), at least one analysis chamber (68), and a receptacle (92) that houses a diluent. A pump system (150) pumps the diluent from the receptacle (92) into the fluidic channel (120) in a first fluid flow direction, and subsequently, pumps the diluent and the bodily sample in a second fluid flow direction, which is a reverse of the first fluid flow direction, to thereby mix the diluent and the bodily sample within the receptacle (92). Other applications are also described.

公开(公告)号：US20210101147A1

公开(公告)日：2021-04-08

申请号：US17064193

申请日：2020-10-06

Applicant: S.D. Sight Diagnostics Ltd.

Inventor： Ido BACHELET ,  Joseph Joel POLLAK ,  Daniel LEVNER ,  Yonatan BILU ,  Noam YORAV-RAPHAEL

IPC: B01L3/00 ,  G01N21/23 ,  G01N21/59 ,  G01N21/64 ,  G01N15/14

Abstract: Apparatus and methods are described including successively acquiring a plurality of microscopic images of a portion of a blood sample, and tracking motion of pixels within the successively acquired microscopic images. Trypomastigote parasite candidates within the blood sample are identified, by identifying pixel motion that is typical of trypomastigote parasites. It is determined that the blood sample is infected with trypomastigote parasites, at least partially in response thereto. An output is generated indicating that that the blood sample is infected with trypomastigote parasites. Other applications are also described.

公开(公告)号：US20220390372A1

公开(公告)日：2022-12-08

申请号：US17770339

申请日：2020-10-22

Applicant: S.D. SIGHT DIAGNOSTICS LTD.

Inventor： Sharon PECKER ,  Yochay Shlomo ESHEL ,  Amir ZAIT ,  Dan GLUCK ,  Noam YORAV-RAPHAEL ,  Arnon HOURI YAFIN ,  Sarah LEVY SCHREIER ,  Joseph Joel POLLAK ,  Daniel LEVNER ,  Yonatan HALPERIN ,  Natalie LEZMY ,  Itamar WEISS

IPC: G01N21/64 ,  G06T7/00

Abstract: Apparatus and methods are described including preparing a blood sample for analysis by depositing the blood sample within a sample chamber (52), and placing the sample chamber, with the blood sample deposited therein, within a microscopy unit (24). One or more microscopic images of the sample chamber (52) with the blood sample deposited therein are acquired, using a microscope of the microscopy unit. Based upon the one or more images, an amount of one or more cell types within the sample chamber that had already settled within the sample chamber, prior to acquisition of the one or more microscopic images is determined. A characteristic of the sample is determined, at least partially in response thereto. Other applications are also described.

公开(公告)号：US20230159982A1

公开(公告)日：2023-05-25

申请号：US18100181

申请日：2023-01-23

Applicant: S.D. Sight Diagnostics Ltd.

Inventor： JOSEPH JOEL POLLAK ,  Daniel LEVNER ,  Yonatan BILU ,  Arnon HOURI YAFIN ,  Noam YORAV-RAPHAEL ,  Yuval GREENFIELD

IPC: C12Q1/68 ,  G01N1/30

CPC classification number: C12Q1/68 ,  G01N1/30

Abstract: Apparatus and methods for use with a blood sample are described. The blood sample is stained with a first dye that predominantly stains DNA, and a second dye that stains at least one other cellular component being different from DNA. A plurality of images of the blood sample are acquired. A candidate object is identified as being a candidate of a given entity. A first stained area, which is stained by the first dye and which is disposed within the candidate object, is identified. A second stained area, which is stained by the second dye and which is disposed within the candidate object, is identified. The entity is detected by determining that features of the stained areas satisfy predetermined criteria associated with the entity. Other applications are also described.

公开(公告)号：US20220381672A1

公开(公告)日：2022-12-01

申请号：US17770365

申请日：2020-10-22

Applicant: S.D. SIGHT DIAGNOSTICS LTD.

Inventor： Sharon PECKER ,  Yochay Shlomo ESHEL ,  Amir ZAIT ,  Dan GLUCK ,  Noam YORAV-RAPHAEL ,  Arnon HOURI YAFIN ,  Sarah LEVY SCHREIER ,  Joseph Joel POLLAK ,  Daniel LEVNER ,  Yonatan HALPERIN ,  Natalie LEZMY ,  Itamar WEISS

IPC: G01N15/14 ,  G01N33/49 ,  G06V20/69

Abstract: Apparatus and methods are described including placing at least a portion of a blood sample within a sample chamber (52), and acquiring microscopic images of the portion of the blood sample. Candidates of a given entity within the blood sample are identified, within the microscopic image. At least some of the candidates as being the given entity are validated, by performing further analysis of the candidates. A count of the candidates of the given entity is compared to a count of the validated candidates of the given entity, and at least the portion of the sample is invalidated from being used for performing at least some measurements upon the sample, at least partially based upon a relationship between the count of candidates and the count of validated candidates. Other applications are also described.