专利检索 ap:("SANOFI PASTEUR INC") AND inv:"Harold KLEANTHOUS" 第 1 页

1.

发明公开
MULTIVALENT INFLUENZA VACCINES 审中-公开

公开(公告)号：US20240269258A1

公开(公告)日：2024-08-15

申请号：US18627824

申请日：2024-04-05

申请人： SANOFI PASTEUR INC.

发明人： Timothy ALEFANTIS , Mario BARRO , Anthony BYERS , Philip DAVIDSON , Maryann GIEL-MOLONEY , Philippe-Alexandre GILBERT , Harold KLEANTHOUS , Armaghan NAIK , Konstantin PUGACHEV , Saranya SRIDHAR , William WARREN , Konstantin ZELDOVICH

IPC分类号： A61K39/145 , A61K9/00 , A61K39/00 , C07K14/005

CPC分类号： A61K39/145 , A61K9/0019 , C07K14/005 , A61K2039/55555 , A61K2039/70 , C12N2760/16322 , C12N2760/16334

摘要： Disclosed are multivalent vaccine or immunogenic compositions comprising influenza virus hemagglutinin (HA) from standard of care influenza virus strains, or ribonucleic acid molecules encoding the same; and one or more influenza virus HA identified or designed by machine learning, or one or more ribonucleic acid molecules that encode the influenza virus HA identified or designed by machine learning. Also disclosed are methods of using the vaccine or immunogenic compositions.

2.

发明公开
MULTIVALENT INFLUENZA VACCINES COMPRISING RECOMBINANT HEMAGGLUTININ AND NEURAMINIDASE AND METHODS OF USING THE SAME 审中-公开

公开(公告)号：US20240277828A1

公开(公告)日：2024-08-22

申请号：US18653422

申请日：2024-05-02

申请人： SANOFI PASTEUR INC

发明人： Timothy ALEFANTIS , Mario BARRO , Anthony BYERS , Guadalupe CORTES-GARCIA , Philippe-Alexandre GILBERT , Harold KLEANTHOUS , Armaghan NAIK , Konstantin PUGACHEV , Saranya SRIDHAR , Thorsten VOGEL , William WARREN

IPC分类号： A61K39/145 , A61K39/00 , A61P37/04

CPC分类号： A61K39/145 , A61P37/04 , A61K2039/54 , A61K2039/545 , A61K2039/55555 , A61K2039/55566 , A61K2039/70

摘要： Disclosed herein are multivalent vaccine or immunogenic compositions comprising one or more recombinant influenza virus hemagglutinin (HA), one or more recombinant influenza virus neuraminidase (NA), and an optional adjuvant. Also disclosed are methods of using the vaccine or immunogenic composition.

3.

发明申请
METHODS OF GENERATING BROADLY PROTECTIVE VACCINE COMPOSITIONS COMPRISING HEMAGGLUTININ 有权

公开(公告)号：US20210128715A1

公开(公告)日：2021-05-06

申请号：US17041784

申请日：2019-03-27

申请人： SANOFI PASTEUR INC.

发明人： Tod STRUGNELL , Eliud OLOO , Raymond OOMEN , Thorsten VOGEL , Harold KLEANTHOUS

IPC分类号： A61K39/145 , C07K14/11 , A61P31/16

摘要： The present disclosure relates to a cluster-based consensus approach for generating recombinant hemagglutinin (HA) polypeptides. The disclosure further relates to influenza vaccine compositions comprising the recombinant HA polypeptides.