公开(公告)号：US20180369815A1

公开(公告)日：2018-12-27

申请号：US15742491

申请日：2015-10-10

Applicant: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCES

Inventor： Hairong ZHENG ,  Fwi LI ,  Felyan CAI ,  Long MENG ,  Chen WANG ,  Chengxiang ZHANG ,  Weibao QIU ,  Yongchuan LI ,  Fei YAN ,  Lili NIU ,  Liufeng GENG ,  Chaowei XU

IPC: B01L3/00 ,  C12N13/00

CPC classification number: B01L3/502761 ,  B01L3/502715 ,  B01L3/50273 ,  B01L3/502792 ,  B01L2200/0647 ,  B01L2200/0652 ,  B01L2300/06 ,  B01L2300/08 ,  B01L2300/0809 ,  B01L2400/0436 ,  B01L2400/0439 ,  B01L2400/0496 ,  C12N13/00 ,  G01N2015/0038 ,  G01N2015/1006

Abstract: Disclosed is a microfluidic system based on an artificially structured acoustic field, comprising a microcavity and a ultrasonic emission device, wherein the microcavity is used to accommodate a solution containing particles, the ultrasonic emission device is used to emit ultrasound, and characterized in further comprising a phononic crystal plate placed in the microcavity, wherein the phononic crystal plate has an artificial cycle structure, and is used to modulate the acoustic field so as to control the particles. Also disclosed is a method of controlling microfluid particles based on an artificially structured acoustic field. In the particular embodiments, since a microcavity, an ultrasonic emission device and a phononic crystal plate are comprised, the ultrasonic emission device is used to emit ultrasound, and the phononic crystal plate has an artificial cycle structure, and is used to modulate the acoustic field so as to control the particles. The method provides a new means for drug delivery, and offers technical support for drug research and development.