PARTICLE ANALYZERS AND PARTICLE TEST CONTROL METHODS AND DEVICES THEREOF

    公开(公告)号:US20170276642A1

    公开(公告)日:2017-09-28

    申请号:US15603384

    申请日:2017-05-23

    CPC classification number: G01N27/4163 G01N15/12 G01N2015/1272 G01N2015/1281

    Abstract: The present disclosure provides a particle analyzer and a particle test control method and device thereof. A method comprises, after acquiring a diluted sample, preserving a part of the diluted sample, and monitoring whether a pore blocking event occurs during a counting process; when the pore blocking event occurs, suspending the test of the sample, and performing an unblocking operation; and after the unblocking operation is completed, controlling a liquid addition system to again acquire the preserved part of the sample from a reaction cell or a tube of the liquid addition system and inject it into a counting cell, and then re-counting the sample in the counting cell by an impedance method. The method makes full use of the residual diluted sample for a second test to eliminate the impact of pore blocking that occurs in the first measurement of the sample on the test result, and there is no need to be place the sample tube again at test position for re-acquisition and re-dilution, thereby reducing the probability of pore blocking.

    FLOW CYTOMETER AND FLUIDIC SYSTEM THEREOF
    4.
    发明申请
    FLOW CYTOMETER AND FLUIDIC SYSTEM THEREOF 有权
    流量计和流体系统

    公开(公告)号:US20150153263A1

    公开(公告)日:2015-06-04

    申请号:US14618931

    申请日:2015-02-10

    Abstract: A flow cytometer and a fluid system are provided. The fluid system comprises a flow cell, a sample providing unit, a waste container, a sheath container, a negative pressure source, a quantitative unit and a sample flow monitoring unit, the negative pressure source, the waste container and the flow cell are connected, a negative pressure source, which provides a negative pressure relative to the sample providing unit for the flow cell so that the sample providing unit causes the sample to flow into the flow cell under the negative pressure, a sample flow monitoring unit monitors a flow of the sample fluid transported from the sample providing unit to the flow cell and outputs a feedback signal reflecting flow changes of the sample fluid in real-time; wherein the controller receives the feedback signal and controls the quantitative unit to adjust a flow of the sheath fluid according to the feedback signal.

    Abstract translation: 提供流式细胞仪和流体系统。 流体系统包括流动池,样品提供单元,废物容器,护套容器,负压源,定量单元和样品流量监测单元,负压源,废物容器和流通池被连接 负压源,其相对于流动池的样品提供单元提供负压,使得样品提供单元使样品在负压下流入流动池,样品流量监测单元监测流动 样品流体从样品提供单元输送到流通池,并输出反映样品流体流动变化的反馈信号; 其中所述控制器接收所述反馈信号并且控制所述定量单元以根据所述反馈信号调节所述鞘液的流量。

    Flow cytometer and fluidic system thereof
    6.
    发明授权
    Flow cytometer and fluidic system thereof 有权
    流式细胞仪及其流体系统

    公开(公告)号:US09170187B2

    公开(公告)日:2015-10-27

    申请号:US14618931

    申请日:2015-02-10

    Abstract: A flow cytometer and a fluid system are provided. The fluid system comprises a flow cell, a sample providing unit, a waste container, a sheath container, a negative pressure source, a quantitative unit and a sample flow monitoring unit, the negative pressure source, the waste container and the flow cell are connected, a negative pressure source, which provides a negative pressure relative to the sample providing unit for the flow cell so that the sample providing unit causes the sample to flow into the flow cell under the negative pressure, a sample flow monitoring unit monitors a flow of the sample fluid transported from the sample providing unit to the flow cell and outputs a feedback signal reflecting flow changes of the sample fluid in real-time; wherein the controller receives the feedback signal and controls the quantitative unit to adjust a flow of the sheath fluid according to the feedback signal.

    Abstract translation: 提供流式细胞仪和流体系统。 流体系统包括流动池,样品提供单元,废物容器,护套容器,负压源,定量单元和样品流量监测单元,负压源,废物容器和流通池被连接 负压源,其相对于流动池的样品提供单元提供负压,使得样品提供单元使样品在负压下流入流动池,样品流量监测单元监测流动 样品流体从样品提供单元输送到流通池,并输出反映样品流体流动变化的反馈信号; 其中所述控制器接收所述反馈信号并且控制所述定量单元以根据所述反馈信号调节所述鞘液的流量。

    PARTICLE ANALYZER AND PARTICLE TEST CONTROL METHOD AND DEVICE THEREOF
    7.
    发明申请
    PARTICLE ANALYZER AND PARTICLE TEST CONTROL METHOD AND DEVICE THEREOF 有权
    粒子分析仪和粒子测试控制方法及其装置

    公开(公告)号:US20140339101A1

    公开(公告)日:2014-11-20

    申请号:US14355547

    申请日:2012-10-25

    CPC classification number: G01N27/4163 G01N15/12 G01N2015/1272 G01N2015/1281

    Abstract: The present disclosure provides a particle analyzer and a particle test control method and device thereof. The method comprises: after acquiring a diluted sample, preserving a part of the diluted sample, and monitoring whether a pore blocking event occurs during a counting process; when the pore blocking event occurs, suspending the test of the sample, and performing an unblocking operation; and after the unblocking operation is completed, controlling a liquid addition system to again acquire the preserved part of the sample from a reaction cell or a tube of the liquid addition system and inject it into a counting cell, and then re-counting the sample in the counting cell by an impedance method. The method makes full use of the residual diluted sample for a second test to eliminate the impact of pore blocking that occurs in the first measurement of the sample on the test result, and there is no need to be place the sample tube again at test position for re-acquisition and re-dilution, thereby reducing the probability of pore blocking.

    Abstract translation: 本公开内容提供了一种粒子分析仪和粒子测试控制方法及其装置。 该方法包括:在获取稀释样品后,保存一部分稀释样品,并监测在计数过程中是否发生孔阻塞事件; 当发生孔堵塞事件时,暂停样品测试,并执行解除操作; 在解封操作完成之后,控制液体添加系统再次从液体添加系统的反应池或管中获取样品的保存部分,并将其注入计数单元,然后重新计数样品 计数单元采用阻抗法。 该方法充分利用残留稀释样品进行第二次测试,以消除在样品的第一次测量中发生的孔阻塞对测试结果的影响,并且不需要将样品管再次放置在测试位置 用于重新获得和再次稀释,从而降低孔阻塞的可能性。

    PARTICLE ANALYZERS AND PARTICLE TEST CONTROL METHODS AND DEVICES THEREOF

    公开(公告)号:US20200232942A1

    公开(公告)日:2020-07-23

    申请号:US16831619

    申请日:2020-03-26

    Abstract: The present disclosure provides a particle analyzer and a particle test control method and device thereof. A method comprises, acquiring a blood sample in a test location; preparing a diluted sample by the acquired sample; after acquiring a diluted sample, monitoring whether a pore blocking event occurs during a counting process; when the pore blocking event occurs, suspending the test of the sample, and performing an unblocking operation; and after the unblocking operation is completed, re-counting the same diluted sample without re-acquiring and re-diluting the blood sample by the impedance method after the unblocking operation.

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