公开(公告)号：US20190189418A1

公开(公告)日：2019-06-20

申请号：US16226003

申请日：2018-12-19

Applicant: SHIMADZU CORPORATION

Inventor： Hiroyuki MIURA ,  Hideaki IZUMI ,  Kiyoshi OGAWA

IPC: H01J49/40 ,  H01J49/02

CPC classification number: H01J49/408 ,  H01J49/022 ,  H01J49/025

Abstract: A microchannel plate (MCP) 41 in an ion detection section 4 multiplies electrons. An anode 42 detects those electrons and produces a current signal. An amplifier 44 converts this signal into a voltage signal. A low-pass filter 5A acting as a smoothing section 5 is located at the output end of the amplifier 44. A waveform-shaping time adjuster 6 adjusts the time constant of the low-pass filter 5A beforehand according to the response time of the MCP 41, mass-to-charge ratio of an ion species to be subjected to the measurement, and duration of the spread of the ion species which depends on device-specific parameters. A plurality of peaks which sequentially appear in the detection signal corresponding to one ion species are thereby smoothed into a single broad peak. Thus, the distinguishability between signal waves and noise components is improved.

公开(公告)号：US20220406588A1

公开(公告)日：2022-12-22

申请号：US17723652

申请日：2022-04-19

Applicant: SHIMADZU CORPORATION

Inventor： Hiroyuki MIURA ,  Hideaki IZUMI

IPC: H01J49/40 ,  H01J49/24

Abstract: A mass spectrometer 1 includes a vacuum container 5 divided into a first chamber 51 containing an ion trap 3 and a second chamber 52 containing a time-of-flight mass spectrometer 4. The ion trap 3 is held within an ion-trap-holding space 610 surrounded by a wall 61. In this wall 61, a cooling-gas discharge port 64 is formed in addition to an introduction-side ion passage port 62 and an ejection-side ion passage port 63. A cooling gas supplied into an ion-capturing space 315 of the ion trap 3 is discharged from the ion-trap-holding space 610 through the three ports. The provision of the cooling-gas discharge port 64 reduces the amount of cooling gas flowing into the ejection-side ion passage port 63 and interfering with the ejection of ions from the ion trap 3 into the time-of-flight mass spectrometer 4. Consequently, the detection intensity of the ions is improved.

公开(公告)号：US20220285143A1

公开(公告)日：2022-09-08

申请号：US17632293

申请日：2020-08-11

Applicant: SHIMADZU CORPORATION

Inventor： Yoshihiro UENO ,  Ryugo MAEDA ,  Yusuke TATEISHI ,  Hiroyuki MIURA

IPC: H01J49/40 ,  H01J49/06 ,  H01J49/42

Abstract: An MT-TOFMS which is one mode of the present invention includes: a linear ion trap (2) configured to temporarily hold ions to be analyzed, and to eject the ions through an ion ejection opening (211) having a shape elongated in one direction; a loop flight section (3) configured to form a loop path (P) capable of making ions repeatedly fly; and a slit part (5) located on an ion path in which the ions ejected from the linear ion trap (2) travel until the ions are introduced into the loop path, the slit part configured to block a portion of the ions in a longitudinal direction of the ion ejection opening (211).

公开(公告)号：US20220189758A1

公开(公告)日：2022-06-16

申请号：US17466565

申请日：2021-09-03

Applicant: SHIMADZU CORPORATION

Inventor： Yusuke TATEISHI ,  Hiroyuki MIURA ,  Hideaki IZUMI

IPC: H01J49/40 ,  H01J49/06

Abstract: Provided is a time-of-flight mass spectrometer including: a loop-orbit defining electrode (21) including an outer electrode (211) and inner electrode (212) located on the outside and inside of a loop orbit, respectively; an ion inlet (22); an ion outlet (23) provided in either the outer or inner electrode; a loop-flight voltage applier (28) configured to apply loop-flight voltages to the outer and inner electrodes, respectively; a set of deflecting electrodes (24) facing each other across a section of an n-th loop orbit, where n is a predetermined number, the deflecting electrodes including a first portion (241) which faces the n-th loop orbit and a second portion (242) which includes other portions; and a voltage applier (29) configured to apply deflecting voltages to the first portion so as to reverse the drifting direction of the ions flying in the n-th loop orbit, and a voltage to the second portion so as to create the loop-flight electric field.

公开(公告)号：US20220059329A1

公开(公告)日：2022-02-24

申请号：US17329341

申请日：2021-05-25

Applicant: SHIMADZU CORPORATION

Inventor： Hiroyuki MIURA ,  Hideaki IZUMI

IPC: H01J49/00 ,  H01J49/04 ,  H01J49/40 ,  H01J49/24

Abstract: Provided is a method for mass spectrometry in which ions to be analyzed are made to come in contact with a cooling gas in a cooling section, such as an ion trap 2, configured to perform the cooling of ions, and kinetic energy is subsequently imparted to the ions so as to introduce the ions into a flight space of a multi-turn time-of-flight mass separator 30 or similar device for separating ions according to their mass-to-charge ratios. According to the present invention, when a known or estimated number of charges of an ion to be analyzed is high, the amount of supply of the cooling gas to the cooling section is set to a lower level than when the number of charges is low. This operation improves the detection sensitivity for ions having large molecular weights and high numbers of charges.

公开(公告)号：US20210111015A1

公开(公告)日：2021-04-15

申请号：US17060692

申请日：2020-10-01

Applicant: SHIMADZU CORPORATION

Inventor： Hiroyuki MIURA ,  Hideaki Izumi

IPC: H01J49/40

Abstract: To compensate for the distortion of the loop-flight electric field with a higher level of accuracy, a multiturn time-of-flight mass spectrometer 1 includes: a main electrode 21 configured to generate, within a predetermined loop-flight space, a loop-flight electric field which is an electric field that makes an ion fly in a loop orbit multiple times, the main electrode having an opening 24 or 25 through which ions are introduced into or extracted from the loop-flight space; a compensating-electrode attachment part 23 made of an insulating material and fixed to the main electrode; and a compensating electrode 22 configured to compensate for a distortion of the loop-flight electric field which occurs in the vicinity of the opening, the compensating electrode being fixed to the compensating-electrode attachment part directly or via a substrate 221 and located in the vicinity of the opening.