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公开(公告)号：US20200158720A1
公开(公告)日：2020-05-21
申请号：US16707501
申请日：2019-12-09
Applicant: STC.UNM
Inventor： David G. Whitten , Harry Craig Pappas , Eric H. Hill , Yue Zhang , Eva Yung Hua Chi , Arjun Thapa , Ying Wang , Patrick L. Donabedian , Kiran Bhaskar
Abstract: Various embodiments relate to p-phenylene ethynylene compounds as bioactive and detection agents. In various embodiments, the present invention provides a method of inducing germination of microbial spores including contacting the microbial spores with a p-phenylene ethynylene compound. In various embodiments, the present invention provides a method for detecting an enzyme, a method of protein analysis, or a method of detecting a chemical agent, including introducing a p-phenylene ethylylene compound to a composition including an enzyme substrate, and analyzing the fluorescence of the p-phenylene ethynylene compound. Various embodiments provide sensors that include a p-phenylene ethynylene compound and an enzyme substrate.
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Patent Agency Ranking
公开(公告)号：US10533991B2
公开(公告)日：2020-01-14
申请号：US15125896
申请日：2015-03-13
Applicant: STC.UNM
Inventor： David G. Whitten , Harry Pappas , Eric H. Hill , Yue Zhang , Eva Yung Hua Chi , Arjun Thapa , Ying Wang , Patrick L. Donabedian , Kiran Bhaskar
Abstract: Various embodiments relate to p-phenylene ethynylene compounds as bioactive and detection agents. In various embodiments, the present invention provides a method of inducing germination of microbial spores including contacting the microbial spores with a p-phenylene ethynylene compound. In various embodiments, the present invention provides a method for detecting an enzyme, a method of protein analysis, or a method of detecting a chemical agent, including introducing a p-phenylene ethynylene compound to a composition including an enzyme substrate, and analyzing the fluorescence of the p-phenylene ethynylene compound. Various embodiments provide sensors that include a p-phenylene ethynylene compound and an enzyme substrate.
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公开(公告)号：US12163953B2
公开(公告)日：2024-12-10
申请号：US16707501
申请日：2019-12-09
Applicant: STC.UNM
Inventor： David G. Whitten , Harry Craig Pappas , Eric H. Hill , Yue Zhang , Eva Yung Hua Chi , Arjun Thapa , Ying Wang , Patrick L Donabedian , Kiran Bhaskar
Abstract: Various embodiments relate to p-phenylene ethynylene compounds as bioactive and detection agents. In various embodiments, the present invention provides a method of inducing germination of microbial spores including contacting the microbial spores with a p-phenylene ethynylene compound. In various embodiments, the present invention provides a method for detecting an enzyme, a method of protein analysis, or a method of detecting a chemical agent, including introducing a p-phenylene ethylylene compound to a composition including an enzyme substrate, and analyzing the fluorescence of the p-phenylene ethynylene compound. Various embodiments provide sensors that include a p-phenylene ethynylene compound and an enzyme substrate.
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公开(公告)号：US10750746B2
公开(公告)日：2020-08-25
申请号：US16192248
申请日：2018-11-15
Applicant: University of Florida Research Foundation, Inc. , STC.UNM
Inventor： David G. Whitten , Kirk S. Schanze , Anand Parthasarathy , Eunkyung Ji , Motokatsu Ogawa , Thomas S. Corbitt , Dimitri Dascier , Ying Wang , Linnea K. Ista , Eric H. Hill
IPC: A01N43/90 , C07C217/14 , C07C309/11 , A01N25/10 , C07D409/14 , C07C217/20 , C07C309/24 , C07D333/16 , C07D487/08 , C08G61/02 , C08G75/00 , C08G61/12 , A01N25/08 , A01N33/10 , A01N33/12 , A01N41/04 , A01N43/10
Abstract: The present disclosure provides novel poly(phenylene ethynylene) (PPE) compounds, methods for synthesizing these compounds, and materials and substances incorporating these compounds. The various PPEs show antibacterial, antiviral and antifungal activity.
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公开(公告)号：US10174042B2
公开(公告)日：2019-01-08
申请号：US15348756
申请日：2016-11-10
Applicant: University of Florida Research Foundation, Inc. , STC.UNM
Inventor： David G. Whitten , Kirk S. Schanze , Anand Parthasarathy , Eunkyung Ji , Motokatsu Ogawa , Thomas S. Corbitt , Dimitri Dascier , Ying Wang , Linnea K. Ista , Eric H. Hill
IPC: C07D487/08 , C07C217/14 , C07C309/11 , C07C217/20 , C07C309/24 , C07D333/16 , C08G61/02 , C08G75/00 , C08G61/12
Abstract: The present disclosure provides novel poly(phenylene ethynylene) (PPE) compounds, methods for synthesizing these compounds, and materials and substances incorporating these compounds. The various PPEs show antibacterial, antiviral and antifungal activity.
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公开(公告)号：US20190116797A1
公开(公告)日：2019-04-25
申请号：US16192248
申请日：2018-11-15
Applicant: University of Florida Research Foundation, Inc. , STC.UNM
Inventor： David G. Whitten , Kirk S. Schanze , Anand Parthasarathy , Eunkyung Ji , Motokatsu Ogawa , Thomas S. Corbitt , Dimitri Dascier , Ying Wang , Linnea K. Ista , Eric H. Hill
IPC: A01N43/90 , C08G61/02 , C07D409/14 , C08G75/00 , A01N25/08 , A01N33/10 , C07C217/14 , A01N25/10 , A01N33/12 , A01N41/04 , A01N43/10 , C08G61/12 , C07D487/08 , C07D333/16 , C07C309/24 , C07C217/20 , C07C309/11
Abstract: The present disclosure provides novel poly(phenylene ethynylene) (PPE) compounds, methods for synthesizing these compounds, and materials and substances incorporating these compounds. The various PPEs show antibacterial, antiviral and antifungal activity.
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