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公开(公告)号：US11491133B2
公开(公告)日：2022-11-08
申请号：US16991771
申请日：2020-08-12
Applicant: Sunovion Pharmaceuticals Inc. , PGI Drug Discovery LLC
Inventor： Carrie A. Bowen , Douglas F. Burdi , Michele L. R. Heffernan , Lee W. Herman , Linghong Xie
IPC: A61K31/352 , A61P25/28 , A61P25/24 , A61P25/08 , A61P25/16 , C07D413/04 , C07D417/04 , C07D405/04 , A61K31/4155 , A61K31/4178 , A61K31/42 , A61K31/427 , A61K31/443 , A61K31/4433 , A61K31/497 , A61K31/506
Abstract: Compounds of Formula I are described as are pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric diseases and disorders in a subject in need are also disclosed.
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公开(公告)号：US11186564B2
公开(公告)日：2021-11-30
申请号：US16322278
申请日：2016-08-04
Applicant: Sunovion Pharmaceuticals Inc.
Inventor： Michele L. R. Heffernan , Larry Wendell Hardy , Scott P. Brown , Lee W. Herman
IPC: C07D211/22 , C07D401/08 , C07D401/14 , C07D401/06 , C07D401/12 , C07D405/06 , C07D471/04 , C07D487/10 , C07D491/107 , C07D311/22 , C07D217/24 , C07D223/08 , C07D235/12 , C07D237/14 , C07D413/06 , C07D241/04 , C07D243/08 , C07D471/08 , C07D491/048 , C07D267/10 , C07D275/04 , C07D211/58 , C07D403/06 , C07D405/12 , A61P25/28 , C07D417/04 , A61P25/18 , C07D513/04 , C07D211/42 , C07D295/104 , C07D207/36 , C07D213/81 , C07D491/20 , C07D249/12 , C07D221/20 , C07D295/088 , C07D311/58 , C07D207/12 , C07D211/44 , C07D265/30 , C07D277/66 , C07D295/027 , C07D295/073 , C07D295/096 , C07D295/108 , C07D307/83 , C07D311/08 , C07D413/08 , C07D471/10
Abstract: Compounds of formula I: are disclosed, as are pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric disorders in a patient in need are also disclosed. Such disorders include depression, bipolar disorder, pain, schizophrenia, obsessive compulsive disorder, addiction, social disorder, attention deficit hyperactivity disorder, an anxiety disorder, autism, a cognitive impairment, or a neuropsychiatric symptom such as apathy, depression, anxiety, psychosis, aggression, agitation, impulse control disorders, and sleep disorders in neurological disorders such as Alzheimer's and Parkinson's diseases.
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公开(公告)号：US09708331B2
公开(公告)日：2017-07-18
申请号：US15013741
申请日：2016-02-02
Applicant: SUNOVION PHARMACEUTICALS INC.
Inventor： Michele L. R. Heffernan , Larry Wendell Hardy , Frank Xinhe Wu , Lakshmi D. Saraswat , Kerry L. Spear
IPC: C07D487/14 , C07D487/04 , C07D471/04 , C07D471/14 , C07D471/20 , C07D487/18 , C07D491/147 , C07D491/20 , C07D491/22 , C07D498/04 , C07D487/10
CPC classification number: C07D487/04 , C07D471/04 , C07D471/14 , C07D471/20 , C07D487/10 , C07D487/14 , C07D487/18 , C07D491/147 , C07D491/20 , C07D491/22 , C07D498/04
Abstract: Compounds that modulate GluR5 activity and methods of using the same are disclosed.
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Patent Agency Ranking
公开(公告)号：US20210093606A1
公开(公告)日：2021-04-01
申请号：US16991771
申请日：2020-08-12
Applicant: Sunovion Pharmaceuticals Inc. , PGI Drug Discovery LLC
Inventor： Carrie A. Bowen , Douglas F. Burdi , Michele L. R. Heffernan , Lee W. Herman , Linghong Xie
IPC: A61K31/352 , C07D413/04 , C07D417/04 , C07D405/04 , A61P25/28 , A61P25/24 , A61P25/08 , A61P25/16 , A61K31/4155 , A61K31/4178 , A61K31/42 , A61K31/427 , A61K31/443 , A61K31/4433 , A61K31/497 , A61K31/506
Abstract: Compounds of Formula I are described as are pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric diseases and disorders in a subject in need are also disclosed.
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公开(公告)号：US10780074B2
公开(公告)日：2020-09-22
申请号：US16051863
申请日：2018-08-01
Applicant: Sunovion Pharmaceuticals Inc. , PGI Drug Discovery LLC
Inventor： Carrie A. Bowen , Douglas F. Burdi , Michele L. R. Heffernan , Lee W. Herman , Linghong Xie
IPC: C07D413/04 , C07D417/04 , C07D405/04 , A61K31/352 , A61P25/28 , A61P25/24 , A61P25/08 , A61P25/16 , A61K31/4155 , A61K31/4178 , A61K31/42 , A61K31/427 , A61K31/443 , A61K31/4433 , A61K31/497 , A61K31/506
Abstract: Compounds of Formula I are described as are pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric diseases and disorders in a subject in need are also disclosed.
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公开(公告)号：US10196403B2
公开(公告)日：2019-02-05
申请号：US15663688
申请日：2017-07-28
Applicant: Sunovion Pharmaceuticals Inc.
Inventor： Taleen G. Hanania , Michele L. R. Heffernan , Philip Glyn Jones , Linghong Xie
IPC: C07D493/04 , C07D313/08 , C07D307/87 , C07D311/76
Abstract: Disclosed are compounds of formula (I): and pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric disease and disorders in a subject in need are also disclosed.
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公开(公告)号：US10196399B2
公开(公告)日：2019-02-05
申请号：US15625604
申请日：2017-06-16
Applicant: SUNOVION PHARMACEUTICALS INC.
Inventor： Michele L. R. Heffernan , Larry Wendell Hardy , Frank Xinhe Wu , Lakshmi D. Saraswat , Kerry L. Spear
IPC: C07D487/04 , C07D471/04 , C07D471/14 , C07D471/20 , C07D487/14 , C07D487/18 , C07D491/147 , C07D491/20 , C07D491/22 , C07D498/04 , C07D487/10
Abstract: Compounds that modulate GluR5 activity and methods of using the same are disclosed.
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公开(公告)号：US10077243B2
公开(公告)日：2018-09-18
申请号：US14299364
申请日：2014-06-09
Applicant: Sunovion Pharmaceuticals Inc.
Inventor： Larry Wendell Hardy , Michele L. R. Heffernan , Frank Xinhe Wu , Lakshmi D. Saraswat , Kerry L. Spear
IPC: A61K31/517 , C07D487/04 , C07D239/88 , C07D403/06 , C07D405/06 , C07D417/06 , C07D471/04 , C07D487/20 , C07D401/14 , C07D413/04 , C07D471/14 , C07D471/20 , C07D487/08 , C07D491/20 , C07D498/04
CPC classification number: C07D239/88 , C07D401/14 , C07D403/06 , C07D405/06 , C07D413/04 , C07D417/06 , C07D471/04 , C07D471/14 , C07D471/20 , C07D487/04 , C07D487/08 , C07D487/20 , C07D491/20 , C07D498/04
Abstract: Provided herein are compounds of formula (I): and pharmaceutical compositions thereof, useful for the treatment of disorders mediated by metabotropic glutamate receptor 5.
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