公开(公告)号：US20160010124A1

公开(公告)日：2016-01-14

申请号：US14620002

申请日：2015-02-11

Applicant: Samsung Electronics Co., Ltd.

Inventor： Taewook Nam ,  Yeoju Song ,  Seunghoon Song ,  Jiae Yun ,  Jinsuk Lee ,  Hunsu Chu ,  Insuk Choi

IPC: C12P7/62 ,  C12N15/70 ,  C12N9/24 ,  C12N9/02 ,  C12N9/88

CPC classification number: C12P7/62 ,  C12N9/0008 ,  C12N9/16 ,  C12N9/88 ,  C12N15/52 ,  C12P7/40

Abstract: A microorganism capable of producing acrylic acid, comprising a genetic modification that increases activity of CoA acylating aldehyde dehydrogenase (ALDH) catalyzing conversion of 3-hydroxypropionaldehyde (3-HPA) to 3-hydroxy propionyl-CoA (3-HP-CoA) and a genetic modification that increases activity of 3-HP-CoA dehydratase catalyzing conversion of 3-HP-CoA to acrylyl-CoA in the microorganism in comparison with a cell that is not genetically engineered; as well as a method of producing the microorganism, and a method of producing acrylic acid using the same.

Abstract translation: 能够生产丙烯酸的微生物，其包含增加催化3-羟基丙醛（3-HPA）向3-羟基丙酰辅酶A（3-HP-CoA）转化的CoA酰化醛脱氢酶（ALDH）的活性的遗传修饰和 与未经遗传工程化的细胞相比，增加了3-HP-CoA脱水酶催化微生物中3-HP-CoA转化为丙烯酰辅酶A的活性的遗传修饰; 以及微生物的制造方法以及使用该微生物的丙烯酸的制造方法。

公开(公告)号：US09506089B2

公开(公告)日：2016-11-29

申请号：US14620049

申请日：2015-02-11

Applicant: Samsung Electronics Co., Ltd.

Inventor： Hunsu Chu ,  Jinho Ahn ,  Taewook Nam ,  Jiae Yun ,  Insuk Choi ,  Yeoju Song ,  Jinsuk Lee

IPC: C12P7/40 ,  C12N1/20 ,  C12N15/52 ,  C12N9/10 ,  C12N9/16 ,  C12N9/00 ,  C12N9/88

CPC classification number: C12P7/40 ,  C12N9/13 ,  C12N9/16 ,  C12N9/88 ,  C12N9/93 ,  C12Y208/03008 ,  C12Y301/02 ,  C12Y402/01 ,  C12Y602/01007 ,  Y02P20/52

Abstract: A microorganism capable of producing an acrylic acid (AA), wherein activities of a pathway producing AA through conversions of 3-HP to 3-HP-CoA and 3-HP-CoA to AA-CoA in the microorganisms are increased; as well as a method of producing the microorganism and a method of producing an acrylic acid by using the same.

Abstract translation: 能够生产丙烯酸（AA）的微生物，其中通过在微生物中将3-HP转化为3-HP-CoA和3-HP-CoA至AA-CoA而产生AA的途径的活性增加; 以及生产微生物的方法以及通过使用该方法生产丙烯酸的方法。

公开(公告)号：US20150329881A1

公开(公告)日：2015-11-19

申请号：US14620049

申请日：2015-02-11

Applicant: Samsung Electronics Co., Ltd.

Inventor： Hunsu Chu ,  Jinho Ahn ,  Taewook Nam ,  Jiae Yun ,  Insuk Choi ,  Yeoju Song ,  Jinsuk Lee

IPC: C12P7/40 ,  C12N9/00 ,  C12N9/16 ,  C12N9/10 ,  C12N9/88

CPC classification number: C12P7/40 ,  C12N9/13 ,  C12N9/16 ,  C12N9/88 ,  C12N9/93 ,  C12Y208/03008 ,  C12Y301/02 ,  C12Y402/01 ,  C12Y602/01007 ,  Y02P20/52

Abstract: A microorganism capable of producing an acrylic acid (AA), wherein activities of a pathway producing AA through conversions of 3-HP to 3-HP-CoA and 3-HP-CoA to AA-CoA in the microorganisms are increased; as well as a method of producing the microorganism and a method of producing an acrylic acid by using the same.

Abstract translation: 能够生产丙烯酸（AA）的微生物，其中通过在微生物中将3-HP转化为3-HP-CoA和3-HP-CoA至AA-CoA而产生AA的途径的活性增加; 以及生产微生物的方法以及通过使用该方法生产丙烯酸的方法。