公开(公告)号：US20140154664A1

公开(公告)日：2014-06-05

申请号：US13941117

申请日：2013-07-12

Applicant: Samsung Electronics Co., Ltd.

Inventor： Min Seok S. KIM ,  Jong-myeon PARK

IPC: C12N5/09 ,  C12N15/10

CPC classification number: C12N5/0693 ,  B01L3/502753 ,  B01L2200/0621 ,  B01L2200/16 ,  B01L2300/0803 ,  B01L2300/0864 ,  B01L2400/0409 ,  B01L2400/0677 ,  B01L2400/086 ,  C12N15/1006

Abstract: A micro fluidic apparatus includes a sample chamber that divides a sample into a first fluid layer and a second fluid layer due to a centrifugal force; a first enriching unit a that receives the first fluid layer from the sample chamber, forms a first complex of a first fine particle and the first target material, and separates the first complex from the first fluid layer using a density difference; and a second enriching unit that receives the second fluid layer from the sample chamber, forms a second complex of a second fine particle and the second target material, and separates the second complex from the second fluid layer using a density difference.

Abstract translation: 微流体装置包括：样品室，其由于离心力将样品分成第一流体层和第二流体层; 从样品室接收第一流体层的第一富集单元a形成第一微粒和第一目标材料的第一复合物，并且使用密度差从第一流体层分离第一络合物; 以及第二富集单元，其从所述样品室接收所述第二流体层，形成第二微粒和所述第二目标材料的第二配合物，并且使用密度差从所述第二流体层分离所述第二配合物。

公开(公告)号：US20140147862A1

公开(公告)日：2014-05-29

申请号：US14026805

申请日：2013-09-13

Applicant: Samsung Electronics Co., Ltd.

Inventor： Min Seok S. KIM ,  Jong-myeon PARK

IPC: G01N33/574

CPC classification number: B01F11/002 ,  B01F11/0002 ,  B01F13/0059 ,  B01L3/50273 ,  B01L3/502746 ,  B01L3/502753 ,  B01L2300/0803 ,  B01L2300/0864 ,  B01L2300/087 ,  B01L2400/0409 ,  B01L2400/0677 ,  B01L2400/084 ,  G01N21/03 ,  G01N21/6428 ,  G01N2015/149

Abstract: A microfluidic apparatus capable of being mounted on a rotation driving unit. When mounted on the rotation driving unit and rotated, a fluid flow is induced in the apparatus due to a centrifugal force. the microfluidic apparatus includes a sample supplying unit that comprises a sample chamber to house a sample and provides a fluid including a target material in which fine beads are bound to a target cell in the sample; a density-gradient separation unit that houses a density gradient material with a lower density than the target material, and receives the fluid from the sample supplying unit to separate the target material from the fluid based on a density difference; a fluid supplying channel connecting the sample supplying unit to the density-gradient separation unit to form a passage of the fluid; and a fluid supplying valve provided to the fluid supplying channel to selectively allow a flow of the fluid.

Abstract translation: 一种能够安装在旋转驱动单元上的微流体装置。 当安装在旋转驱动单元上并旋转时，由于离心力而在设备中引起流体流动。 所述微流体装置包括样品供应单元，所述样品供应单元包括样品室以容纳样品并提供包含目标材料的流体，在所述样品中，细小珠结合到样品中的靶细胞; 密度梯度分离单元，其容纳具有比目标材料低的密度的密度梯度材料，并且从所述样品供应单元接收流体，以基于密度差从所述流体分离所述目标材料; 流体供给通道，其将样品供给单元连接到密度梯度分离单元，以形成流体的通道; 以及设置到流体供应通道以选择性地允许流体流动的流体供应阀。