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    METHOD OF SEPARATING TARGET CELL IN BIOLOGICAL SAMPLE
    1.
    发明申请
    METHOD OF SEPARATING TARGET CELL IN BIOLOGICAL SAMPLE 有权
    在生物样品中分离目标细胞的方法

    公开(公告)号：US20130309662A1

    公开(公告)日：2013-11-21

    申请号：US13949320

    申请日：2013-07-24

    Applicant: Samsung Electronics Co., Ltd.

    Inventor： Jong-myeon PARK

    IPC: C12N5/09

    CPC classification number: C12N5/0693 ,  C07K16/30

    Abstract: Provided is a method of separating a rare cell from a sample comprising incubating a sample comprising a rare cell and a second cell with a particle comprising a moiety capable of binding to the rare cell to form a complex comprising the particle and the rare cell; applying the mixture to a medium having a density gradient; and centrifuging the mixture to separate the complex from the second cell.

    Abstract translation: 提供了从样品中分离稀有细胞的方法，包括用包含能够与稀有细胞结合的部分的颗粒将包含稀有细胞和第二细胞的样品孵育以形成包含该颗粒和稀有细胞的复合物; 将混合物施加到具有密度梯度的介质中; 并离心混合物以将复合物与第二细胞分离。

    MICROFLUIDIC APPARATUS
    9.
    发明申请
    MICROFLUIDIC APPARATUS 有权
    微流体装置

    公开(公告)号：US20140357466A1

    公开(公告)日：2014-12-04

    申请号：US14144165

    申请日：2013-12-30

    Applicant: Samsung Electronics Co., Ltd.

    Inventor： Hui-sung MOON ,  Min-Seok S. KIM ,  Jong-myeon PARK

    IPC: B04B7/02 ,  B04B11/00

    CPC classification number: B01L3/502715 ,  B01L2200/027 ,  B01L2300/041 ,  B01L2300/0803 ,  B01L2300/0887 ,  B01L2400/0409 ,  B01L2400/0677 ,  B01L2400/0683 ,  B04B5/0407 ,  B04B7/02 ,  B04B11/00 ,  G01N1/4077 ,  G01N2035/00495

    Abstract: A microfluidic apparatus that is mounted on a rotation driver and induces a flow of a fluid according to a centrifugal force includes a lower structure having a microfluidic structure including a recovery chamber for accommodating a target material separated from a sample and a channel for forming an inflow path of the target material to the recovery chamber; an upper plate forming an upper wall of the recovery chamber and the channel; and a lid formed integrally to the upper plate and removable from the upper plate to open at least a part of a top of the recovery chamber.

    Abstract translation: 安装在旋转驱动器上并根据离心力引起流体流动的微流体装置包括具有微流体结构的下部结构，该微结构结构包括用于容纳从样品分离的靶材料的回收室和用于形成流入物 目标材料到回收室的路径; 形成所述回收室的上壁和所述通道的上板; 以及与所述上板一体地形成并且可从所述上板移除以打开所述回收室的顶部的至少一部分的盖。

    MICROFLUIDIC APPARATUS AND METHOD OF ENRICHING TARGET MATERIAL IN BIOLOGICAL SAMPLE BY USING THE SAME
    10.
    发明申请
    MICROFLUIDIC APPARATUS AND METHOD OF ENRICHING TARGET MATERIAL IN BIOLOGICAL SAMPLE BY USING THE SAME 有权
    微生物装置及其使用方法在生物样品中增强目标物质

    公开(公告)号：US20140154664A1

    公开(公告)日：2014-06-05

    申请号：US13941117

    申请日：2013-07-12

    Applicant: Samsung Electronics Co., Ltd.

    Inventor： Min Seok S. KIM ,  Jong-myeon PARK

    IPC: C12N5/09 ,  C12N15/10

    CPC classification number: C12N5/0693 ,  B01L3/502753 ,  B01L2200/0621 ,  B01L2200/16 ,  B01L2300/0803 ,  B01L2300/0864 ,  B01L2400/0409 ,  B01L2400/0677 ,  B01L2400/086 ,  C12N15/1006

    Abstract: A micro fluidic apparatus includes a sample chamber that divides a sample into a first fluid layer and a second fluid layer due to a centrifugal force; a first enriching unit a that receives the first fluid layer from the sample chamber, forms a first complex of a first fine particle and the first target material, and separates the first complex from the first fluid layer using a density difference; and a second enriching unit that receives the second fluid layer from the sample chamber, forms a second complex of a second fine particle and the second target material, and separates the second complex from the second fluid layer using a density difference.

    Abstract translation: 微流体装置包括：样品室，其由于离心力将样品分成第一流体层和第二流体层; 从样品室接收第一流体层的第一富集单元a形成第一微粒和第一目标材料的第一复合物，并且使用密度差从第一流体层分离第一络合物; 以及第二富集单元，其从所述样品室接收所述第二流体层，形成第二微粒和所述第二目标材料的第二配合物，并且使用密度差从所述第二流体层分离所述第二配合物。

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