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1.发明申请FUSION PROTEIN COMPRISING TARGETING MOIETY, CLEAVAGE SITE, AND CELL MEMBRANE PENETRATING DOMAIN, AND USE THEREOF 有权融合蛋白质包含靶向区域，CLEAVAGE SITE和细胞膜穿透域及其使用公开(公告)号：US20160008480A1
公开(公告)日：2016-01-14
申请号：US14794542
申请日：2015-07-08
Applicant: SAMSUNG ELECTRONICS CO., LTD.
Inventor： Jae Il Lee , Soshin Ahn , Jung Min Kim , Jungmin Lee , Jung-Hoon Lee
CPC classification number: C07K16/30 , A61K38/00 , A61K47/6851 , C07K14/47 , C07K16/2863 , C07K2318/20 , C07K2319/10 , C07K2319/33 , C07K2319/50
Abstract: A fusion protein including a targeting moiety, a cleavage site, and a cell membrane penetrating domain, a conjugate including the fusion protein and a bioactive molecule, and methods employing the fusion protein and the conjugate are provided.
Abstract translation: 提供了包含靶向部分，切割位点和细胞膜穿透结构域的融合蛋白，包含融合蛋白和生物活性分子的缀合物，以及使用融合蛋白和缀合物的方法。
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公开(公告)号：US09470677B2
公开(公告)日：2016-10-18
申请号：US14554955
申请日：2014-11-26
Applicant: Samsung Electronics Co., Ltd.
Inventor： Jungmin Lee , Jae Il Lee , Soshin Ahn , Hye Yoon Kang
IPC: G01N33/574 , G01N33/50
CPC classification number: G01N33/502 , C12N5/0006 , C12N2501/998 , G01N2333/705 , G01N2500/10
Abstract: A cell having a surface coated with Annexin A1 (ANXA1), a method of detecting a substance binding to ANXA1 using the cell, and a method of preparing the cell are provided.
Abstract translation: 提供了具有被膜蛋白A1（ANXA1）包被的表面的细胞，使用该细胞检测与ANXA1结合的物质的方法以及制备该细胞的方法。
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公开(公告)号：US09617344B2
公开(公告)日：2017-04-11
申请号：US14794542
申请日：2015-07-08
Applicant: Samsung Electronics Co., Ltd.
Inventor： Jae Il Lee , Soshin Ahn , Jung Min Kim , Jungmin Lee , Jung-Hoon Lee
IPC: A61K38/00 , A61K39/00 , A61K39/395 , A61K38/16 , C12N5/00 , C12N15/00 , C07H21/04 , C07K16/00 , C12P21/08 , C07K16/30 , A61K47/48 , C07K16/28
CPC classification number: C07K16/30 , A61K38/00 , A61K47/6851 , C07K14/47 , C07K16/2863 , C07K2318/20 , C07K2319/10 , C07K2319/33 , C07K2319/50
Abstract: A fusion protein including a targeting moiety, a cleavage site, and a cell membrane penetrating domain, a conjugate including the fusion protein and a bioactive molecule, and methods employing the fusion protein and the conjugate are provided.
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