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    DUAL-PURPOSE LAPAROSCOPIC SURGICAL DEVICE
    1.
    发明申请
    DUAL-PURPOSE LAPAROSCOPIC SURGICAL DEVICE 审中-公开
    双目镜手术器械

    公开(公告)号：US20120316541A1

    公开(公告)日：2012-12-13

    申请号：US13491030

    申请日：2012-06-07

    申请人： Sarah J. Young ,  Pablo Garcia ,  Karen Shakespear ,  Sanjeev Dutta ,  Susan Kim

    发明人： Sarah J. Young ,  Pablo Garcia ,  Karen Shakespear ,  Sanjeev Dutta ,  Susan Kim

    IPC分类号： A61B17/00

    CPC分类号： A61B18/1482 ,  A61B17/0218 ,  A61B2017/00353 ,  A61B2017/320044 ,  A61B2018/00494 ,  A61B2018/00601

    摘要： A medical device intended for use in performing minimally invasive procedures is provided. The device is intended for performing a pyloromyotomy in pediatric surgery, laparascopically. A key aspect of embodiments of the device is the dual-purpose functionality of the device as it combines both spreading of tissue and cutting of tissue, using mono- or bi-polar electric energy or a knife, with the same medical device. The use of the device requires fewer tool changes during surgery, improving safety and ease of use, as well as reducing surgery time. The devices lend themselves to torelatively cheaper manufacturing processes and lower overall cost compared to existing devices. They would also require less training time compared to current laparoscopic tools.

    摘要翻译： 提供了用于执行微创程序的医疗设备。 该装置用于在儿科手术中进行幽门螺旋切除术。 该装置的实施例的一个关键方面是该装置的两用功能，因为它使用单一或双极电能或刀与相同的医疗装置组合了组织的铺展和组织的切割。 在手术中使用该装置需要较少的刀具更换，提高安全性和使用方便性，以及减少手术时间。 与现有设备相比，这些设备可以相对较便宜的制造过程和降低整体成本。 与目前的腹腔镜手术相比，它们也需要更少的训练时间。

    Controllable dexterous endoscopic device
    2.
    发明授权
    Controllable dexterous endoscopic device 有权
    可控灵巧的内窥镜装置

    公开(公告)号：US08388519B2

    公开(公告)日：2013-03-05

    申请号：US12180387

    申请日：2008-07-25

    申请人： Pablo Garcia ,  Thomas Low ,  Bryan Chavez ,  Harsha Prahlad ,  Natalia Isaza ,  Sanjeev Dutta

    发明人： Pablo Garcia ,  Thomas Low ,  Bryan Chavez ,  Harsha Prahlad ,  Natalia Isaza ,  Sanjeev Dutta

    IPC分类号： A61B1/00

    CPC分类号： B25J18/06 ,  H02N1/006 ,  Y10T74/20323

    摘要： A selectively rigidizable endoscopic device is described. In one aspect, an endoscopic medical device is described that includes a flexible inner tube having a first lumen, a flexible outer tube that receives the inner tube, and a multiplicity of overlapping, rigidizable scale-like strips. Each scale-like strip is coupled with the inner tube and positioned between the inner and outer tubes. Of particular note, the overlapping strips are actuatable between a non-rigidized state in which overlapping strips are slideable relative to one another and a rigidized state in which overlapping strips are not slideable relative to one another.

    摘要翻译： 描述了可选择性地可硬化的内窥镜装置。 在一个方面，描述了一种内窥镜医疗装置，其包括具有第一内腔的柔性内管，容纳内管的柔性外管和多个重叠的，可硬化的鳞片状条。 每个鳞片状条与内管连接并定位在内管和外管之间。 特别值得注意的是，重叠的条带可在非刚性状态下致动，在非刚性状态下，重叠的条可相对于彼此滑动，并且其中重叠的条不能相对于彼此滑动的刚性状态。

    System and Method for Measuring Movement of a Component from Rings Magnetized in a Magnetically Hard Layer
    3.
    发明申请
    System and Method for Measuring Movement of a Component from Rings Magnetized in a Magnetically Hard Layer 有权
    用于测量在磁性硬层中磁化的环的组分的运动的系统和方法

    公开(公告)号：US20110062948A1

    公开(公告)日：2011-03-17

    申请号：US12953919

    申请日：2010-11-24

    申请人： Donald C. Arns, JR. ,  Pablo Garcia

    发明人： Donald C. Arns, JR. ,  Pablo Garcia

    IPC分类号： G01B7/14

    CPC分类号： F15B15/2861 ,  F15B15/2846 ,  G01D5/00 ,  G01D5/24423 ,  G01D5/24438 ,  G01D5/24447 ,  G01D5/24476

    摘要： A position-sensing system includes a first component (e.g., a cylinder) and a second component (e.g., a piston rod) movably coupled to the first component for movement with respect thereto. A magnetically hard layer on the second component provides a recording medium. Regions of the magnetically hard layer are magnetized as magnetized rings around the second component. Magnetic-field sensors are coupled to the first component in proximity of the magnetically hard layer on the second component to sense the rings of magnetized regions. Each of the magnetic field sensors senses flux from each of the rings of magnetized regions as the second component is moving with respect to the first component and, in response to sensing the rings of magnetized regions, generates signals used to determine position of the second component.

    摘要翻译： 位置感测系统包括可移动地联接到第一部件以相对于其移动的第一部件（例如，气缸）和第二部件（例如，活塞杆）。 第二组件上的磁性硬层提供记录介质。 磁性硬层的区域被磁化为围绕第二组分的磁化环。 磁场传感器在第二部件上的磁性硬层附近耦合到第一部件以感测磁化区域的环。 当第二部件相对于第一部件移动时，每个磁场传感器感测来自磁化区域的每个环的磁通，并且响应于感测磁化区域的环，产生用于确定第二部件的位置的信号 。

    System and method of perpendicularly magnetizing position information in a magnetically hard layer of a moving component
    4.
    发明授权
    System and method of perpendicularly magnetizing position information in a magnetically hard layer of a moving component 有权
    在运动部件的磁性硬层中垂直磁化位置信息的系统和方法

    公开(公告)号：US07755350B2

    公开(公告)日：2010-07-13

    申请号：US12252342

    申请日：2008-10-15

    申请人： Donald C. Arns, Jr. ,  Pablo Garcia

    发明人： Donald C. Arns, Jr. ,  Pablo Garcia

    IPC分类号： G01B7/14

    CPC分类号： F15B15/2861 ,  F15B15/2846 ,  G01D5/00 ,  G01D5/24423 ,  G01D5/24438 ,  G01D5/24447 ,  G01D5/24476

    摘要： A position-sensing system magnetically senses the position of a piston rod moving with respect to a cylinder. A magnetically hard layer on the piston rod provides a recording medium. Information is perpendicularly magnetized in regions of the magnetically hard layer. These regions provide an encoding scheme for determining the position of the piston rod. Magnetic-field sensors are positioned over redundant tracks of magnetically recorded regions. Each magnetic-field sensor positioned over a given track senses the same magnetized regions while the piston rod moves with respect to the cylinder. Other magnetic-field sensors can sense ambient fields for use in performing common-mode rejection. A write head can dynamically repair damaged or erased regions detected by the magnetic-field sensors. Energized by a battery-backup power source, the magnetic-field sensors and associated circuitry can continue to track movement of the piston rod when the machinery is off.

    摘要翻译： 位置感测系统磁性地感测相对于气缸移动的活塞杆的位置。 活塞杆上的磁性硬层提供了一种记录介质。 信息在磁性硬层的区域中垂直磁化。 这些区域提供用于确定活塞杆的位置的编码方案。 磁场传感器位于磁记录区域的冗余轨道上。 位于给定轨道上方的每个磁场传感器在活塞杆相对于气缸移动时感测相同的磁化区域。 其他磁场传感器可以感测用于执行共模抑制的环境场。 写头可以动态修复由磁场传感器检测到的损坏或擦除的区域。 由电池备用电源供电，当机械关闭时，磁场传感器和相关电路可以继续跟踪活塞杆的运动。

    SYSTEM AND METHOD OF MAGNETICALLY SENSING POSITION OF A MOVING COMPONENT
    5.
    发明申请
    SYSTEM AND METHOD OF MAGNETICALLY SENSING POSITION OF A MOVING COMPONENT 有权
    移动组件的磁感测位置的系统和方法

    公开(公告)号：US20070262770A1

    公开(公告)日：2007-11-15

    申请号：US11782005

    申请日：2007-07-24

    申请人： Donald Arns ,  Pablo Garcia

    发明人： Donald Arns ,  Pablo Garcia

    IPC分类号： G01B7/14

    CPC分类号： F15B15/2861 ,  F15B15/2846 ,  G01D5/00 ,  G01D5/24423 ,  G01D5/24438 ,  G01D5/24447 ,  G01D5/24476

    摘要： A position-sensing system magnetically senses the position of a first component moving with respect to a second component. A magnetically hard layer on the first component provides a recording medium. Information is magnetically recorded in regions of the magnetically hard layer. These regions provide a relative encoding scheme for determining the position of the first component. Magnetic-field sensors are positioned over redundant tracks of magnetically recorded regions. Each magnetic-field sensor positioned over a given track senses the same magnetized regions while the first component moves with respect to the second component. Other magnetic-field sensors can sense ambient fields for use in performing common-mode rejection. A write head can dynamically repair damaged or erased regions detected by the magnetic-field sensors. Energized by a battery-backup power source, the magnetic-field sensors and associated circuitry can continue to track movement of the first component when the machinery is off.

    摘要翻译： 位置感测系统磁性地感测相对于第二部件移动的第一部件的位置。 第一组件上的磁性硬层提供记录介质。 信息被磁记录在磁性硬层的区域中。 这些区域提供用于确定第一部件的位置的相对编码方案。 磁场传感器位于磁记录区域的冗余轨道上。 位于给定轨道上方的每个磁场传感器在第一部件相对于第二部件移动时感测相同的磁化区域。 其他磁场传感器可以感测用于执行共模抑制的环境场。 写头可以动态修复由磁场传感器检测到的损坏或擦除的区域。 由电池备用电源供电，当机械关闭时，磁场传感器和相关电路可以继续跟踪第一部件的运动。

    Endogenous retrovirus up-regulated in prostate cancer
    6.
    发明申请
    Endogenous retrovirus up-regulated in prostate cancer 审中-公开
    内源性逆转录病毒在前列腺癌中上调

    公开(公告)号：US20060275747A1

    公开(公告)日：2006-12-07

    申请号：US10498033

    申请日：2002-12-09

    申请人： Stephen Hardy ,  Pablo Garcia ,  Lewis Williams ,  Jaime Escobedo

    发明人： Stephen Hardy ,  Pablo Garcia ,  Lewis Williams ,  Jaime Escobedo

    IPC分类号： C12Q1/70

    CPC分类号： C12Q1/6886 ,  C12Q1/702 ,  C12Q2600/136 ,  C12Q2600/158 ,  G01N33/57434

    摘要： A specific member of the HERV-K family located in chromosome 22 at 20.428 megabases (22q11.2) has been found to be preferentially and significantly up-regulated in prostate tumors. The invention provides methods for diagnosing prostate cancer, comprising the step of detecting in a patient sample the presence or absence of an expression product of the virus. The virus has five features not seen in other HERV-K members: (1) its own specific nucleotide sequence, and consequently amino acid sequences; (2) tandem 5′ LTRs; (3) a fragmented 3′ LTR; (4) an env gene interrupted by an alu insertion; and (5) unique gag sequences.

    摘要翻译： 已经发现，在20.428兆比特（22q11.2）位于22号染色体上的HERV-K家族的特异成员在前列腺肿瘤中优先显着上调。 本发明提供了诊断前列腺癌的方法，包括在患者样品中检测病毒表达产物的存在或不存在的步骤。 该病毒在其他HERV-K成员中没有看到五个特征：（1）其自身的特异核苷酸序列，因此是氨基酸序列; （2）串联5'LTR; （3）碎片3'LTR; （4）由alu插入中断的env基因; 和（5）独特的gag序列。

    Selectively rigidizable and actively steerable articulatable device
    9.
    发明授权
    Selectively rigidizable and actively steerable articulatable device 有权
    选择性可固化和积极引导的关节运动装置

    公开(公告)号：US08488295B2

    公开(公告)日：2013-07-16

    申请号：US13399618

    申请日：2012-02-17

    申请人： Pablo Garcia ,  Thomas Low ,  Bryan Chavez ,  Harsha Prahlad

    发明人： Pablo Garcia ,  Thomas Low ,  Bryan Chavez ,  Harsha Prahlad

    IPC分类号： A61B1/005

    CPC分类号： B25J18/06 ,  H02N1/006 ,  Y10T74/20323

    摘要： A selectively rigidizable and actively steerable device is described. In one aspect, an articulatable device is described that includes a flexible inner tube having a first lumen, a flexible outer tube that receives the inner tube, and a multiplicity of overlapping, rigidizable scale-like strips. Each scale-like strip is coupled with the inner tube and positioned between the inner and outer tubes. Of particular note, the overlapping strips are actuatable between a non-rigidized state in which overlapping strips are slideable relative to one another and a rigidized state in which overlapping strips are not slideable relative to one another.

    摘要翻译： 描述了一种选择性可刚性化和主动操纵的装置。 在一个方面，描述了一种可铰接装置，其包括具有第一内腔的柔性内管，容纳内管的柔性外管和多个重叠的，可硬化的鳞片状条。 每个鳞片状条与内管连接并定位在内管和外管之间。 特别值得注意的是，重叠的条带可在非刚性状态下致动，在非刚性状态下，重叠的条可相对于彼此滑动，并且其中重叠的条不能相对于彼此滑动的刚性状态。