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公开(公告)号：US20030153900A1
公开(公告)日：2003-08-14
申请号：US10131268
申请日：2002-04-23
申请人： Sarnoff Corporation
发明人： John Gregory Aceti , Sterling Eduard McBride , Richard Morgan Moroney III , Christopher Carter Gregory , Peter John Zanzucchi
IPC分类号： A61M031/00
CPC分类号： A61B5/150984 , A61B5/1411 , A61B5/14514 , A61B5/14532 , A61B5/14546 , A61B5/1455 , A61B5/150022 , A61B5/150076 , A61B5/150213 , A61B5/150389 , A61B5/150503 , A61B5/150526 , A61B5/150755 , A61B5/15087 , A61B5/150969 , A61B5/15109 , A61B5/15119 , A61B5/15123 , A61B5/15146 , A61B5/15153 , A61B5/15163 , A61B5/155 , A61B5/157 , A61B5/681 , A61B5/6833 , A61B2560/0412 , A61B2560/0443 , A61M37/0015 , A61M2037/0023 , A61M2037/0038 , A61M2209/088 , A61M2230/201 , G01N33/491
摘要： The invention relates to analyte monitoring/drug (pharmaceutical agent) delivery device. The invention is suited for monitoring various blood constituents such as glucose. The device has a housing that at least partially encloses a plurality of microneedles disposed on a carrier and an electronics portion. Each microneedle is in fluid communication with a corresponding microchannel. Each microneedle is individually addressable. That is, each microneedle can be extended and retracted individually via an actuator. The electronics portion includes a processor and associated circuitry (e.g., memory, supporting electronics and the like), a motor or the like, a sensor, a power supply (e.g., battery) and optionally an interface. In general, the processor controls the operation of the device and is data communication with the actuator, motor, sensor and interface. The invention provides for autonomous operation, that is, without intervention of the user. The invention can optionally provide for calibration without intervention of the user. The invention can also provide for semi-continuous monitoring for day and night time. The invention can provide for up to four, or more, weeks of operation. The invention can provide for a device that is relative small in size, and therefore unobtrusive. The invention can also provide for device with remote control and interactive electronics. The invention may be also used for the delivery of various pharmaceutical agents including high potency drugs to minimize patient intervention and minimize discomfort.
摘要翻译： 本发明涉及分析物监测/药物（药剂）递送装置。 本发明适用于监测各种血液成分如葡萄糖。 该装置具有至少部分地包围设置在载体和电子部分上的多个微针的壳体。 每个微针与相应的微通道流体连通。 每个微针都可单独寻址。 也就是说，每个微针可以通过致动器单独地延伸和缩回。 电子部分包括处理器和相关联的电路（例如，存储器，支持电子设备等），电动机等，传感器，电源（例如电池）和可选的接口。 通常，处理器控制设备的操作，并且与致动器，电动机，传感器和接口进行数据通信。 本发明提供自主操作，即不用户干预。 本发明可以任选地提供校准而不需要用户的干预。 本发明还可以提供昼夜半连续监测。 本发明可以提供多达四个或更多周的操作。 本发明可以提供尺寸相对较小并因此不显眼的装置。 本发明还可以为具有远程控制和交互式电子设备的设备提供。 本发明还可以用于递送包括高效药物在内的各种药剂，以最小化患者干预并使不适程度最小化。
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公开(公告)号：US20020037130A1
公开(公告)日：2002-03-28
申请号：US09925885
申请日：2001-08-03
申请人： Sarnoff Corporation
IPC分类号： G02B006/35
CPC分类号： G02B6/3538 , G02B6/352 , G02B6/355 , G02B6/3574 , G02B26/004 , G02F1/0126 , G02F1/073 , G02F1/29
摘要： An optical switch comprising a fluid contained within a reservoir having a characteristic, a plurality of waveguides are located proximate to the fluid and an actuator is coupled to the fluid for changing the characteristic of the fluid to switch a light signal from one waveguide to another waveguide.
摘要翻译： 包括容纳在具有特征的储存器中的流体的光学开关，多个波导位于流体附近，并且致动器联接到流体，用于改变流体的特性以将光信号从一个波导切换到另一个波导 。
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公开(公告)号：US20020048425A1
公开(公告)日：2002-04-25
申请号：US09874886
申请日：2001-06-05
申请人： Sarnoff Corporation
IPC分类号： G02B006/35
CPC分类号： G02B6/3538 , G02B6/355 , G02B6/357 , G02B6/3596
摘要： An apparatus for switching an optical signal comprising a first optical waveguide, a second optical waveguide aligned with the first and a third optical waveguide intersecting the previously mentioned pair. At the region of intersection of the waveguides, a microchannel containing a liquid is disposed. Also included in the microchannel is an electrokinetic pump used to move the fluid into and out of the microchannel.
摘要翻译： 一种用于切换光信号的装置，包括第一光波导，与第一和第三光波导对准的第二光波导，与第一光波导相交。 在波导的相交区域，设置含有液体的微通道。 微通道中还包括用于将流体移入和移出微通道的电动泵。
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