公开(公告)号：US07852076B2

公开(公告)日：2010-12-14

申请号：US12423431

申请日：2009-04-14

申请人： Satoshi Hirata ,  Hisaaki Ochi ,  Yo Taniguchi ,  Tetsuhiko Takahashi ,  Hiroyuki Takeuchi

发明人： Satoshi Hirata ,  Hisaaki Ochi ,  Yo Taniguchi ,  Tetsuhiko Takahashi ,  Hiroyuki Takeuchi

IPC分类号： G01V3/00

CPC分类号： A61B5/411 ,  A61B5/0037 ,  A61B5/055 ,  A61B5/415 ,  A61B5/416 ,  A61B5/418 ,  A61B5/7257 ,  G01R33/389 ,  G01R33/485

摘要： The present invention provides a magnetic resonance imaging system capable of performing spectrum measurement even when a magnetic resonant frequency changes during MRS measurement. A time-varying rate of a water magnetic resonant frequency is measured in advance before the MRS measurement. The amount of change in water magnetic resonant frequency during the MRS measurement is predicted from the measured time-varying rate. With the predicted value as the reference, a transmission frequency of an RF magnetic field irradiated in a signal suppression pulse sequence, a transmission frequency of an RF magnetic field for excitation and inversion and a received frequency at the detection of a magnetic resonance signal in a sequence of the MRS measurement are respectively set. A high-precision spectrum measurement is hence enabled.

摘要翻译： 本发明提供一种磁共振成像系统，即使MRS测量期间磁共振频率发生变化，也能进行光谱测量。 在MRS测量之前，预先测量水磁共振频率的时变速率。 MRS测量期间水磁共振频率的变化量根据测量的时变速率预测。 以预测值为参考，在信号抑制脉冲序列中照射的RF磁场的传输频率，用于激励和反转的RF磁场的传输频率和在检测磁共振信号中的接收频率 分别设置MRS测量的顺序。 因此，能够进行高精度的频谱测量。

公开(公告)号：US09097778B2

公开(公告)日：2015-08-04

申请号：US13140484

申请日：2010-02-03

申请人： Yoshitaka Bito ,  Satoshi Hirata ,  Hisaaki Ochi ,  Koji Hirata ,  Toru Shirai ,  Yosuke Otake

发明人： Yoshitaka Bito ,  Satoshi Hirata ,  Hisaaki Ochi ,  Koji Hirata ,  Toru Shirai ,  Yosuke Otake

IPC分类号： G01R33/485 ,  G01R33/563

CPC分类号： G01R33/485 ,  G01R33/56341

摘要： In the diffusion spectroscopic imaging, in which intensity of molecular diffusion is imaged with separating chemical substances, with suppressing artifacts resulting from object motion of an object, spatial resolution, spectral band and SNR are maintained, and measurement accuracy is enhanced. A measurement for acquiring diffusion SI data is repeated a plurality of times with changing acquisition timing, phase variation of each measurement result is corrected, and a diffusion SI image is reconstructed from the corrected measurement results. In addition, the phase variation is calculated for every point in the space from the diffusion SI data acquired by each measurement or navigation data obtained by each measurement. The phase correction is independently performed for every point in the space.

摘要翻译： 在通过分离化学物质成像分子扩散强度的扩散光谱成像中，通过抑制由物体的物体运动产生的伪影，保持了空间分辨率，光谱带和SNR，并且提高了测量精度。 通过改变获取定时多次重复获取扩散SI数据的测量，校正每个测量结果的相位变化，并从校正的测量结果重建扩散SI图像。 此外，根据通过各测量获得的扩散SI数据或通过每次测量获得的导航数据，计算空间中每个点的相位变化。 对于空间中的每一个点都独立执行相位校正。

公开(公告)号：US08030924B2

公开(公告)日：2011-10-04

申请号：US11797878

申请日：2007-05-08

申请人： Yoshitaka Bito ,  Hisaaki Ochi ,  Yo Taniguchi ,  Satoshi Hirata ,  Toru Shirai

发明人： Yoshitaka Bito ,  Hisaaki Ochi ,  Yo Taniguchi ,  Satoshi Hirata ,  Toru Shirai

IPC分类号： G01V3/00

CPC分类号： G01R33/485 ,  G01R33/5608

摘要： A magnetic resonance imaging system capable of conducting spectroscopic imaging with an improved SNR without degrading the spatial resolution includes edge-preserving filter processing means for spectroscopic imaging. The edge-preserving filter processing means executes processing including the steps of calculating spectral similarity in spatial neighborhoods (spatially neighboring voxels) at each voxel in spectroscopic imaging data, calculating a spectral weight according to the spectral similarity, and conducting weighted smoothing for compounding spectra of spatial neighborhoods (spatially neighboring voxels) according to the spectral weight.

摘要翻译： 能够在不降低空间分辨率的情况下以改善的SNR进行光谱成像的磁共振成像系统包括用于分光成像的边缘保留滤波处理装置。 边缘保留滤波处理装置执行处理，其包括以下步骤：计算分光成像数据中的每个体素的空间邻域（空间相邻体素）中的频谱相似度，根据频谱相似度计算频谱权重，以及进行加权平滑化， 根据光谱权重的空间邻域（空间相邻体素）。

公开(公告)号：US20090201020A1

公开(公告)日：2009-08-13

申请号：US12423431

申请日：2009-04-14

申请人： Satoshi Hirata ,  Hisaaki Ochi ,  Yo Taniguchi ,  Tetsuhiko Takahashi ,  Hiroyuki Takeuchi

发明人： Satoshi Hirata ,  Hisaaki Ochi ,  Yo Taniguchi ,  Tetsuhiko Takahashi ,  Hiroyuki Takeuchi

IPC分类号： G01R33/48

CPC分类号： A61B5/411 ,  A61B5/0037 ,  A61B5/055 ,  A61B5/415 ,  A61B5/416 ,  A61B5/418 ,  A61B5/7257 ,  G01R33/389 ,  G01R33/485

摘要： The present invention provides a magnetic resonance imaging system capable of performing spectrum measurement even when a magnetic resonant frequency changes during MRS measurement. A time-varying rate of a water magnetic resonant frequency is measured in advance before the MRS measurement. The amount of change in water magnetic resonant frequency during the MRS measurement is predicted from the measured time-varying rate. With the predicted value as the reference, a transmission frequency of an RF magnetic field irradiated in a signal suppression pulse sequence, a transmission frequency of an RF magnetic field for excitation and inversion and a received frequency at the detection of a magnetic resonance signal in a sequence of the MRS measurement are respectively set. A high-precision spectrum measurement is hence enabled.

摘要翻译： 本发明提供一种磁共振成像系统，即使MRS测量期间磁共振频率发生变化，也能进行光谱测量。 在MRS测量之前，预先测量水磁共振频率的时变速率。 MRS测量期间水磁共振频率的变化量根据测量的时变速率预测。 以预测值为参考，在信号抑制脉冲序列中照射的RF磁场的传输频率，用于激励和反转的RF磁场的传输频率和在检测磁共振信号中的接收频率 分别设置MRS测量的顺序。 因此，能够进行高精度的频谱测量。

公开(公告)号：US07518362B2

公开(公告)日：2009-04-14

申请号：US10562643

申请日：2004-06-02

申请人： Satoshi Hirata ,  Hisaaki Ochi ,  Yo Taniguchi ,  Tetsuhiko Takahashi ,  Hiroyuki Takeuchi

发明人： Satoshi Hirata ,  Hisaaki Ochi ,  Yo Taniguchi ,  Tetsuhiko Takahashi ,  Hiroyuki Takeuchi

IPC分类号： G01V3/00

CPC分类号： A61B5/411 ,  A61B5/0037 ,  A61B5/055 ,  A61B5/415 ,  A61B5/416 ,  A61B5/418 ,  A61B5/7257 ,  G01R33/389 ,  G01R33/485

摘要： The present invention provides a magnetic resonance imaging system capable of performing spectrum measurement even when a magnetic resonant frequency changes during MRS measurement. A time-varying rate of a water magnetic resonant frequency is measured in advance before the MRS measurement. The amount of change in water magnetic resonant frequency during the MRS measurement is predicted from the measured time-varying rate. With the predicted value as the reference, a transmission frequency of an RF magnetic field irradiated in a signal suppression pulse sequence, a transmission frequency of an RF magnetic field for excitation and inversion and a received frequency at the detection of a magnetic resonance signal in a sequence of the MRS measurement are respectively set. A high-precision spectrum measurement is hence enabled.

摘要翻译： 本发明提供一种磁共振成像系统，即使MRS测量期间磁共振频率发生变化，也能进行光谱测量。 在MRS测量之前，预先测量水磁共振频率的时变速率。 MRS测量期间水磁共振频率的变化量根据测量的时变速率预测。 以预测值为参考，在信号抑制脉冲序列中照射的RF磁场的传输频率，用于激励和反转的RF磁场的传输频率和在检测磁共振信号中的接收频率 分别设置MRS测量的顺序。 因此，能够进行高精度的频谱测量。

公开(公告)号：US20120049845A1

公开(公告)日：2012-03-01

申请号：US13140484

申请日：2010-02-03

申请人： Yoshitaka Bito ,  Satoshi Hirata ,  Hisaaki Ochi ,  Koji Hirata ,  Toru Shirai ,  Yosuke Otake

发明人： Yoshitaka Bito ,  Satoshi Hirata ,  Hisaaki Ochi ,  Koji Hirata ,  Toru Shirai ,  Yosuke Otake

IPC分类号： G01R33/32

CPC分类号： G01R33/485 ,  G01R33/56341

摘要： In the diffusion spectroscopic imaging, in which intensity of molecular diffusion is imaged with separating chemical substances, with suppressing artifacts resulting from object motion of an object, spatial resolution, spectral band and SNR are maintained, and measurement accuracy is enhanced. A measurement for acquiring diffusion SI data is repeated a plurality of times with changing acquisition timing, phase variation of each measurement result is corrected, and a diffusion SI image is reconstructed from the corrected measurement results. In addition, the phase variation is calculated for every point in the space from the diffusion SI data acquired by each measurement or navigation data obtained by each measurement. The phase correction is independently performed for every point in the space.

摘要翻译： 在通过分离化学物质成像分子扩散强度的扩散光谱成像中，通过抑制由物体的物体运动产生的伪影，保持了空间分辨率，光谱带和SNR，并且提高了测量精度。 通过改变获取定时多次重复获取扩散SI数据的测量，校正每个测量结果的相位变化，并从校正的测量结果重建扩散SI图像。 此外，根据通过各测量获得的扩散SI数据或通过每次测量获得的导航数据，计算空间中的每个点的相位变化。 对于空间中的每一个点都独立执行相位校正。

公开(公告)号：US07355405B2

公开(公告)日：2008-04-08

申请号：US11630766

申请日：2005-07-20

申请人： Satoshi Hirata ,  Hisaaki Ochi

发明人： Satoshi Hirata ,  Hisaaki Ochi

IPC分类号： G01V3/00

CPC分类号： G01R33/56563

摘要： Provided is a magnetic resonance imaging system capable of reducing degradation in a magnetic resonance spectrum derived from a change in a static magnetic field. A sequence controller performs non-water-suppressed spectrum measurement (pre-scan) cyclically during water-suppressed spectrum measurement (main scan) accompanied by repetitive measurement intended for averaging of signals, and cyclically detects a water resonant frequency (water-signal peak position) and a phase value at a water-signal peak from an obtained non-water-suppressed spectrum (the cyclic pre-scan makes it possible to sense a time-varying rate of static magnetic field strength (resonant frequency)). For the water-suppressed spectrum measurement (main scan) succeeding the pre-scan, a reception-initiating phase value that is used to detect a magnetic resonance signal is set to a value calculated using the phase value at the water-signal peak position detected during the pre-scan. For averaging of measured magnetic resonance signals, data items are shifted by the value calculated from the phase value at the water-signal peak position detected during the pre-scan. Thereafter, the averaging is carried out.

摘要翻译： 本发明提供能够降低由静磁场变化引起的磁共振谱的劣化的磁共振成像系统。 序列控制器在水抑制频谱测量（主扫描）期间循环执行非水抑制频谱测量（预扫描），伴随着用于信号平均的重复测量，并循环检测水谐振频率（水信号峰位置 ）和来自所获得的非水分抑制光谱的水信号峰值处的相位值（循环预扫描使得可以感测静态磁场强度（谐振频率）的时变速率）。 对于预扫描之后的水抑制谱测量（主扫描），将用于检测磁共振信号的接收开始相位值设定为使用检测到的水信号峰位置的相位值计算出的值 在预扫描期间。 对于测量的磁共振信号的平均，数据项被移位由在预扫描期间检测的水信号峰值位置处的相位值计算的值。 此后，进行平均化。

公开(公告)号：US20060255802A1

公开(公告)日：2006-11-16

申请号：US10562643

申请日：2004-06-02

申请人： Satoshi Hirata ,  Hisaaki Ochi ,  Yo Taniguchi ,  Tetsuhiko Takahashi ,  Hiroyuki Takeuchi

发明人： Satoshi Hirata ,  Hisaaki Ochi ,  Yo Taniguchi ,  Tetsuhiko Takahashi ,  Hiroyuki Takeuchi

IPC分类号： G01V3/00

CPC分类号： A61B5/411 ,  A61B5/0037 ,  A61B5/055 ,  A61B5/415 ,  A61B5/416 ,  A61B5/418 ,  A61B5/7257 ,  G01R33/389 ,  G01R33/485

摘要： The present invention provides a magnetic resonance imaging system capable of performing spectrum measurement even when a magnetic resonant frequency changes during MRS measurement. A time-varying rate of a water magnetic resonant frequency is measured in advance before the MRS measurement. The amount of change in water magnetic resonant frequency during the MRS measurement is predicted from the measured time-varying rate. With the predicted value as the reference, a transmission frequency of an RF magnetic field irradiated in a signal suppression pulse sequence, a transmission frequency of an RF magnetic field for excitation and inversion and a received frequency at the detection of a magnetic resonance signal in a sequence of the MRS measurement are respectively set. A high-precision spectrum measurement is hence enabled.

摘要翻译： 本发明提供一种磁共振成像系统，即使MRS测量期间磁共振频率发生变化，也能进行光谱测量。 在MRS测量之前，预先测量水磁共振频率的时变速率。 MRS测量期间水磁共振频率的变化量根据测量的时变速率预测。 以预测值为参考，在信号抑制脉冲序列中照射的RF磁场的传输频率，用于激励和反转的RF磁场的传输频率和在检测磁共振信号中的接收频率 分别设置MRS测量的顺序。 因此，能够进行高精度的频谱测量。

公开(公告)号：US06222365B1

公开(公告)日：2001-04-24

申请号：US09155245

申请日：1998-09-24

申请人： Yo Taniguchi ,  Hisaaki Ochi ,  Kenichi Okajima ,  Satoshi Hirata

发明人： Yo Taniguchi ,  Hisaaki Ochi ,  Kenichi Okajima ,  Satoshi Hirata

IPC分类号： G01V300

CPC分类号： G01R33/482 ,  G01R33/54

摘要： In a magnetic resonance imaging apparatus including a pulse sequence control unit for controlling a pulse sequence to acquire echoes while both a radio frequency magnetic field and a gradient magnetic field are applied to an object under examination present in a static magnetic field; and an image reconstructing unit for reconstructing an image based upon the acquired echoes, the pulse sequence control unit is comprised of a spatial resolution control unit for setting spatial resolution A along a readout gradient magnetic field direction of the reconstructed image; and a gradient magnetic field strength control unit for applying such a readout gradient magnetic field that spatial resolution B determined by a strength of the readout gradient magnetic field and a sampling period becomes coarser than the spatial resolution A. The image reconstructing unit reconstructs an image while a minimum unit of the spatial resolution A is set as a width of one pixel of a reconstructed image along a readout direction.

摘要翻译： 在包括脉冲序列控制单元的磁共振成像设备中，所述脉冲序列控制单元用于控制脉冲序列以获取回波，同时将射频磁场和梯度磁场施加到存在于静态磁场中的被检查物体; 所述脉冲序列控制单元包括用于沿着所述重建图像的读出梯度磁场方向设定空间分辨率A的空间分辨率控制单元，所述图像重建单元用于基于所获取的回波重建图像。 以及梯度磁场强度控制单元，用于施加由读出梯度磁场的强度和采样周期确定的空间分辨率B变得比空间分辨率A更粗糙的读出梯度磁场。图像重建单元重建图像，同时 将空间分辨率A的最小单位设置为沿着读出方向的重建图像的一个像素的宽度。

公开(公告)号：US08400148B2

公开(公告)日：2013-03-19

申请号：US12307809

申请日：2006-12-20

申请人： Satoshi Hirata ,  Hisaaki Ochi

发明人： Satoshi Hirata ,  Hisaaki Ochi

IPC分类号： G01V3/00

CPC分类号： G01R33/485 ,  G01R33/5607

摘要： Magnetic resonance imaging apparatus enabling highly precise spectrum measurement even when resonance frequency changes during MRS or MRSI measurement. When a pulse sequence for suppressing water signals, and an MRS or MRSI pulse sequence are sequentially executed to carry out measurement using repetitive measurement for signal integration or repetitive measurement for phase encoding, signal Sig0 from water is measured with the pulse sequence for suppressing water signals in every repetitive measurement. When the resonance frequency of water deviates from an excitation band region, nuclear magnetization included in water molecules is not excited, so that water signal strength deceases, and therefore change of static magnetic field intensity can be detected by monitoring change of signal Sig0.When water signal strength decreases below a predetermined value, it is determined that resonance frequency has shifted, preliminary measurement for detecting water resonance frequency is performed, and various frequencies are corrected during the repetitive measurement.

摘要翻译： 磁共振成像装置即使在MRS或MRSI测量期间谐振频率发生变化时也能进行高精度的光谱测量。 当用于抑制水信号的脉冲序列和MRS或MRSI脉冲序列被顺序地执行以使用用于信号积分的重复测量或用于相位编码的重复测量进行测量时，用用于抑制水信号的脉冲序列测量来自水的信号Sig0 在每次重复测量中。 当水的共振频率偏离激发带区域时，水分子中包含的核磁化不被激发，从而可以通过监测信号Sig0的变化来检测水信号强度的衰减，从而可以检测静态磁场强度的变化。当水 信号强度降低到预定值以下，则确定谐振频率已经偏移，执行用于检测水共振频率的初步测量，并且在重复测量期间校正各种频率。