公开(公告)号：US20030055455A1

公开(公告)日：2003-03-20

申请号：US09957975

申请日：2001-09-20

申请人： SciMed Life Systems, Inc.

发明人： Dachuan Yang ,  Jaydeep Y. Kokate

IPC分类号： A61B017/08

CPC分类号： A61B17/0057 ,  A61B2017/00575 ,  A61B2017/00592 ,  A61B2017/00606 ,  A61B2017/00619 ,  A61B2017/00623

摘要： Systems and methods for treating septal defects. A system for treating septal defects may comprise a first catheter having a distal end and a first lumen, a second catheter having a distal end a second lumen, a bridge member extending between the distal end of the first catheter and the distal end of the second catheter, and a first patch adapted to be disposed within the first lumen and movable out of the first lumen along the bridge member. A second patch may be used and be connectable to the first patch.

公开(公告)号：US20020151844A1

公开(公告)日：2002-10-17

申请号：US10154186

申请日：2002-05-22

申请人： Scimed Life Systems, Inc., a subsidiary of Boston Scientific Corporation.

发明人： Dachuan Yang ,  Joel Stanslaski ,  Lixiao Wang

IPC分类号： A61M031/00

CPC分类号： A61L31/16 ,  A61F2/0077 ,  A61F2/91 ,  A61F2/915 ,  A61F2/958 ,  A61F2002/91541 ,  A61F2002/91558 ,  A61F2250/0067 ,  A61L29/085 ,  A61L29/16 ,  A61L31/10 ,  A61L2300/416 ,  A61L2300/608 ,  A61L2420/08

摘要： A medical device, such as a stent or balloon of a balloon catheter which includes a body portion which has an exterior surface which contacts, at least in part, a vessel wall during treatment. The body portion is expandable from a first position, wherein the body portion is sized for insertion into the vessel lumen, to a second position, wherein at least a portion of the exterior surface is in contact with the lumen wall. The medical device includes a first coating disposed over at least a portion of the exterior surface of the body portion with the first coating including a drug or therapeutic substance which is intended for controlled release from the surface. The medical device further includes a second coating overlying at least a substantial portion of the first coating. The second coating includes a material that is generally impervious to elution of the drug or therapeutic substance therethrough when the body portion is in a first position when inserted into the vessel lumen. The material of the second coating is relatively inelastic so that the second coating fractures during expansion of the body portion to the second position to allow elution of therapeutic substance through a multiplicity of fissures formed through the second coating.

摘要翻译： 一种医疗装置，例如球囊导管的支架或球囊，其包括主体部分，该主体部分具有在治疗期间至少部分地与血管壁接触的外表面。 主体部分从第一位置可膨胀，其中主体部分的尺寸适于插入血管腔，到达第二位置，其中外表面的至少一部分与腔壁接触。 医疗装置包括设置在主体部分的外表面的至少一部分上的第一涂层，第一涂层包括用于从表面受控释放的药物或治疗物质。 医疗装置还包括覆盖第一涂层的至少大部分的第二涂层。 第二涂层包括当插入血管内腔时主体部分处于第一位置时通常不透过药物或治疗物质的洗脱的材料。 第二涂层的材料相对无弹性，使得第二涂层在主体部分膨胀到第二位置期间断裂，以允许通过穿过第二涂层形成的多个裂缝洗脱治疗物质。

公开(公告)号：US20030135197A1

公开(公告)日：2003-07-17

申请号：US10050476

申请日：2002-01-15

申请人： SciMed Life Systems, Inc.

发明人： Lixiao Wang ,  Dachuan Yang ,  Joe Randall ,  (Bruce) Yiqun Wang

IPC分类号： A61M025/00

CPC分类号： A61M25/1034 ,  A61M25/0009 ,  A61M25/0045 ,  A61M25/005 ,  A61M25/0662 ,  A61M25/1025 ,  A61M2025/0183 ,  B29C65/02 ,  B29C65/16 ,  B29C65/48 ,  B29C65/486 ,  B29C66/1122 ,  B29C66/5221 ,  B29C66/5227 ,  B29C66/52271 ,  B29C66/71 ,  B29C66/742 ,  B29L2031/7542 ,  C08J5/121 ,  C09J5/06 ,  C09J2400/163 ,  C09J2400/226 ,  B29K2079/085 ,  B29K2079/08 ,  B29K2077/00 ,  B29K2071/00

摘要： Various coupling agents are disclosed to form lap joints between metallic and polymeric surfaces within catheters and other medical devices. The coupling agents disclosed in the present invention can be applied directly to a metallic surface, or the coupling agents may be incorporated within a polymeric material. In certain circumstances, the mere application of the coupling agent between the two dissimilar materials provides sufficient adhesive strength to form a fatigue-free lap joint bond. Alternative methods utilize coupling agents as primers for later thermal bonding and laser welding procedures that form lap joint bonds.

摘要翻译： 公开了各种偶联剂以在导管和其它医疗装置内的金属和聚合物表面之间形成搭接接头。 本发明中公开的偶联剂可以直接施加到金属表面，也可以将偶联剂掺入聚合物材料中。 在某些情况下，仅在两种不同材料之间施加偶联剂可以提供足够的粘合强度以形成无疲劳的搭接接头。 替代方法使用偶联剂作为后续热粘合和激光焊接程序的底漆，形成搭接接合键。