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144 条记录 (耗时 0.047 秒)

    DYNAMIC ENERGY CONTROL OF A CHARGED PARTICLE IMAGING/TREATMENT APPARATUS AND METHOD OF USE THEREOF
    4.
    发明申请
    DYNAMIC ENERGY CONTROL OF A CHARGED PARTICLE IMAGING/TREATMENT APPARATUS AND METHOD OF USE THEREOF 审中-公开
    充电颗粒成像/处理设备的动态能量控制及其使用方法

    公开(公告)号：US20170043187A1

    公开(公告)日：2017-02-16

    申请号：US15334122

    申请日：2016-10-25

    申请人： W. Davis Lee ,  Mark R. Amato ,  Scott Penfold

    发明人： W. Davis Lee ,  Mark R. Amato ,  Scott Penfold

    IPC分类号： A61N5/10

    CPC分类号： A61N5/1077 ,  A61B6/032 ,  A61B6/4258 ,  A61B6/5205 ,  A61N5/1037 ,  A61N5/1039 ,  A61N5/1044 ,  A61N5/1067 ,  A61N5/1069 ,  A61N5/107 ,  A61N5/1082 ,  A61N2005/1054 ,  A61N2005/1087 ,  A61N2005/1095 ,  A61N2005/1097 ,  G21K1/08 ,  G21K5/04

    摘要： The invention comprises a beam adjustment method and apparatus used to perform energy adjustments on circulating charged particles in a synchrotron previously accelerated to a starting energy with a traditional accelerator of the synchrotron. The beam adjustment system uses a radio-frequency modulated potential difference applied along a longitudinal path of the circulating charged particles to accelerate or decelerate the circulating charged particles. Optionally, the beam adjustment system phase shifts the applied radio-frequency field to accelerate or decelerate the circulating charged particles while tightening spatial distribution of a grouped bunch of the circulating charged particles. Optionally, the beam adjustment system simultaneously radially focuses the circulating charged particles using two or more gaps with focusing and/or defocusing edges. The beam adjustment system facilitates treating multiple layers or depths of the tumor without hysteresis and/or between the repeating slow steps of reloading the synchrotron.

    摘要翻译： 本发明包括一种光束调节方法和装置，用于对先前加速到同步加速器的传统加速器的起始能量的同步加速器中的循环带电粒子进行能量调节。 光束调节系统使用沿着循环带电粒子的纵向路径施加的射频调制电位差来加速或减速循环的带电粒子。 可选地，光束调节系统相位移动所施加的射频场，以加速或减速循环的带电粒子，同时收紧分组的循环带电粒子的空间分布。 可选地，光束调节系统同时使用具有聚焦和/或散焦边缘的两个或多个间隙同时使循环的带电粒子聚焦。 束调节系统有助于治疗肿瘤的多个层或深度，而不会滞后和/或重新加载同步加速器的重复慢步骤之间。

    CHARGED PARTICLE CANCER THERAPY BEAM STATE DETERMINATION SYSTEM AND METHOD OF USE THEREOF
    7.
    发明申请
    CHARGED PARTICLE CANCER THERAPY BEAM STATE DETERMINATION SYSTEM AND METHOD OF USE THEREOF 审中-公开

    公开(公告)号：US20180078790A1

    公开(公告)日：2018-03-22

    申请号：US15823148

    申请日：2017-11-27

    申请人： W. Davis Lee ,  Scott Penfold ,  Mark R. Amato ,  Lou Wainwright

    发明人： W. Davis Lee ,  Scott Penfold ,  Mark R. Amato ,  Lou Wainwright

    IPC分类号： A61N5/10

    摘要： The invention comprises a method and apparatus for determining state of a positively charged particle, such as a proton, for use in imaging a tumor of a patient prior to and/or concurrent with cancer therapy. The imaging system comprises: (1) a beam transport path of the positively charged particle sequentially passing through a patient, through a first time of flight detector, and, after traversing a pathlength, at least into a second time of flight detector and (2) a beam state determination system configured to: use elapsed time between detection at the first and second time of flight detectors and the pathlength to determine a residual beam energy, which, when compared to a known incident beam energy, is used in generation of an image of the tumor. An optional beam energy degrading element increases time differences between the time of flight detectors.

    X-RAY DETECTOR FOR PROTON TRANSIT DETECTION APPARATUS AND METHOD OF USE THEREOF
    10.
    发明申请
    X-RAY DETECTOR FOR PROTON TRANSIT DETECTION APPARATUS AND METHOD OF USE THEREOF 审中-公开
    用于原子发射检测装置的X射线探测器及其使用方法

    公开(公告)号：US20170056688A1

    公开(公告)日：2017-03-02

    申请号：US15348625

    申请日：2016-11-10

    申请人： Scott Penfold ,  W. Davis Lee ,  Mark R. Amato

    发明人： Scott Penfold ,  W. Davis Lee ,  Mark R. Amato

    IPC分类号： A61N5/10

    CPC分类号： A61N5/1067 ,  A61B6/032 ,  A61B6/4258 ,  A61B6/5205 ,  A61N5/1037 ,  A61N5/1044 ,  A61N5/1049 ,  A61N5/1069 ,  A61N5/107 ,  A61N5/1077 ,  A61N5/1082 ,  A61N2005/1054 ,  A61N2005/1087 ,  A61N2005/1095 ,  A61N2005/1097 ,  G21K1/08 ,  G21K5/04

    摘要： The invention comprises a method and apparatus for probing a tumor of a patient using positively charged particles, comprising the steps of: (1) sequentially delivering sets of varied and known positively charged particles to a patient; (2) after transmission through the patient, sequentially detecting a residual energy of each of the sets of positively charged particles; and (3) determining a water equivalent thickness of a probed path of the patient using a plot of the detector response as a function of residual energy that is fit with a curve. The analyzer relates a half maximum of the fit curve, such as a Gaussian curve, to the water equivalent thickness of the sampled beam path. Repeated measurements as a function of incident angle and/or position of the incident charged particles allows generation of an image of the sample, such as a computed tomography image.

    摘要翻译： 本发明包括用于使用带正电荷的微粒探测患者肿瘤的方法和装置，其包括以下步骤：（1）将一系列不同且已知的带正电荷的颗粒顺序递送给患者; （2）通过病人传送后，依次检测各带正电粒子的剩余能量; 和（3）使用与曲线拟合的残余能量的函数的检测器响应的图来确定患者的探测路径的水当量厚度。 分析仪将拟合曲线的半值最大值（例如高斯曲线）与采样光束路径的水当量厚度相关联。 作为入射角度和/或入射带电粒子的位置的函数的重复测量允许产生样本的图像，例如计算机断层摄影图像。