DNA backbone editing for DNA data storage

    公开(公告)号:US11990184B2

    公开(公告)日:2024-05-21

    申请号:US17031664

    申请日:2020-09-24

    IPC分类号: C12P19/34 G11C13/02

    CPC分类号: G11C13/02 C12P19/34

    摘要: Methods of writing data to a DNA strand by inserting data-encoding oligos or symbols into a DNA backbone. One particular method of synthesizing a DNA strand encoding data includes cleaving a DNA backbone into multiple segments, and pasting a plurality of data-encoding oligo symbols between the multiple segments, with the terminal ends of the segments joining homologous terminal ends of the symbols, resulting in the DNA strand encoding data comprising alternating segments and symbols.

    Methods of gene assembly and their use in DNA data storage

    公开(公告)号:US11066661B2

    公开(公告)日:2021-07-20

    申请号:US16856947

    申请日:2020-04-23

    摘要: A system for DNA gene assembly that utilizes a DNA symbol library and a DNA linker library. The symbol library has a number of DNA symbols each having a first overhanging end and a second overhanging end different than and non-complimentary to the first end, the first and second ends being the same nucleotides for each DNA symbol. The linker library has pairs of DNA linkers, a first linker of a pair having a first overhanging end and a second overhanging end and a second linker of the pair having a first overhanging end and a second overhanging end, the first end of the first linker being the same nucleotides for each first linker and the second end of the second linker being the same nucleotides for each second linker, wherein the second end of the first linker and the first end of the second linker have complementary nucleotides. The first linker joins to the first end of a DNA symbol and the second linker joins to the second end of another DNA symbol.

    Procedure for setting laser and heater power in HAMR device

    公开(公告)号:US10090011B2

    公开(公告)日:2018-10-02

    申请号:US14716148

    申请日:2015-05-19

    IPC分类号: G11B5/60 G11B5/00

    摘要: A heater power of a heat-assisted magnetic recording head is set to an initial power to induce an initial head-medium clearance. For a plurality of iterations, a heater power at an optimum laser power is determined that achieve a target clearance. If differences in the heater power and optimum laser power between the two subsequent iterations are below a threshold, the iterations are stopped and the heater power and the optimum laser power for one of the two subsequent iterations is used as an operational heater power and laser power for the heat-assisted magnetic recording head.