Indazole compounds
    1.
    发明授权
    Indazole compounds 失效
    吲唑化合物

    公开(公告)号:US08008506B2

    公开(公告)日:2011-08-30

    申请号:US12569295

    申请日:2009-09-29

    IPC分类号: C07D231/56 A61K31/416

    摘要: Provided are compounds represented by the following formula (A-1) and formula (1), or salts thereof. The compounds of formula (A-1) and formula (1) or salts thereof have β3 adrenergic receptor agonist activity, and thus are useful as therapeutic and prophylactic agent for diabetes mellitus, obesity, hyperlipidemia, depression, diseases caused by gallstones or hypermotility of the biliary tract, diseases caused by hyperactivity of the digestive tract, interstitial cystitis, overactive bladder or urinary incontinence, or as therapeutic and prophylactic agents for diseases concomitant with decreased tears.

    摘要翻译: 提供由下式(A-1)和式(1)表示的化合物或其盐。 式(A-1)和式(1)的化合物或其盐具有β肾上腺素能受体激动剂活性,因此可用作糖尿病,肥胖症,高脂血症,抑郁症,由胆结石引起的疾病或 胆汁过度运动,消化道多动症,间质性膀胱炎,膀胱过度活动性膀胱或尿失禁引起的疾病,或伴随泪液减少的疾病的治疗和预防剂。

    INDAZOLE COMPOUNDS
    2.
    发明申请
    INDAZOLE COMPOUNDS 失效
    INDAZOLE化合物

    公开(公告)号:US20100160256A1

    公开(公告)日:2010-06-24

    申请号:US12569295

    申请日:2009-09-29

    摘要: Provided are compounds represented by the following formula (A-1) and formula (1), or salts thereof. The compounds of formula (A-1) and formula (1) or salts thereof have 133 adrenergic receptor agonist activity, and thus are useful as therapeutic and prophylactic agent for diabetes mellitus, obesity, hyperlipidemia, depression, diseases caused by gallstones or hypermotility of the biliary tract, diseases caused by hyperactivity of the digestive tract, interstitial cystitis, overactive bladder or urinary incontinence, or as therapeutic and prophylactic agents for diseases concomitant with decreased tears.

    摘要翻译: 提供由下式(A-1)和式(1)表示的化合物或其盐。 式(A-1)和式(1)的化合物或其盐具有133肾上腺素能受体激动剂活性,因此可用作糖尿病,肥胖症,高脂血症,抑郁症,由胆结石引起的疾病或高运动障碍的治疗和预防剂 胆道,消化道多动症,间质性膀胱炎,膀胱过度活动或尿失禁引起的疾病,或伴随泪液减少的疾病的治疗和预防剂。

    Indazole derivatives
    3.
    发明授权
    Indazole derivatives 失效
    吲唑衍生物

    公开(公告)号:US08304443B2

    公开(公告)日:2012-11-06

    申请号:US12569324

    申请日:2009-09-29

    IPC分类号: A61K31/415 C07D231/56

    CPC分类号: C07D231/56

    摘要: Compounds represented by the Formula (A-1) and the Formula (1) or salt thereof are provided. The compounds represented by the Formula (A-1) and the Formula (1) or salt thereof have a β3 adrenergic receptor agonist activity, and therefore are useful as an agent for the prevention and treatment of diabetes, obesity, hyperlipidemia, depression, biliary stone, a disorder derived from hyperactivity of biliary tract, a disorder derived from hyperactivity of digestive tract, interstitial cystitis, overactive bladder, urinary incontinence or a disorder derived from decreased tear secretion, etc.

    摘要翻译: 提供由式(A-1)和式(1)表示的化合物或其盐。 由式(A-1)和式(1)表示的化合物或其盐具有β-肾上腺素能受体激动剂活性,因此可用作预防和治疗糖尿病,肥胖症,高脂血症,抑郁症的药剂 ,胆石,一种源于胆道多动症的病症,源自消化道多动症,间质性膀胱炎,膀胱过度活动,尿失禁或由泪液分泌减少引起的疾病等疾病。

    INDAZOLE ANALOG
    4.
    发明申请
    INDAZOLE ANALOG 审中-公开
    INDAZOLE模拟

    公开(公告)号:US20120225909A1

    公开(公告)日:2012-09-06

    申请号:US13498524

    申请日:2010-09-30

    摘要: [Objective] To provide a drug that selectively stimulates the β3-adrenergic receptors, particularly a drug capable of preferentially stimulating the β3-adrenergic receptors over the α1-adrenergic receptors. This drug can be used in the treatment and prevention of diabetes, obesity, hyperlipidemia, depression, cholelithiasis, diseases caused by biliary hyperkinesia, diseases caused by hyperfunction of the gastrointestinal tract, interstitial cystitis, overactive bladder or urinary incontinence, diseases associated with decreased lacrimation, and the like.[Solution] Indazole analogs represented by the general formula (I) or a salt thereof. Drugs that contains these indazole analogs or a salt thereof as the active ingredient.

    摘要翻译: [目的]提供一种选择性刺激肾上腺素能受体的药物,特别是能够优先刺激α1-肾上腺素能受体的β-肾上腺素能受体的药物。 该药物可用于治疗和预防糖尿病,肥胖症,高脂血症,抑郁症,胆石病,胆汁性运动障碍引起的疾病,由胃肠道功能亢进引起的疾病,间质性膀胱炎,膀胱过度活动或尿失禁,与流泪相关的疾病 ,等等。 [溶液]由通式(I)表示的吲唑类似物或其盐。 含有这些吲唑类似物或其盐作为活性成分的药物。

    Viscous coupling and suspension apparatus
    5.
    发明授权
    Viscous coupling and suspension apparatus 失效
    粘性联轴器和悬挂装置

    公开(公告)号:US08672111B2

    公开(公告)日:2014-03-18

    申请号:US12677315

    申请日:2009-03-11

    申请人: Yasuhiro Wada

    发明人: Yasuhiro Wada

    摘要: A viscous coupling includes a case body for forming a working chamber which contains the viscous fluid, a shaft inserted into the case body in such a manner that the shaft is relatively rotatable with respect to the case body, a plurality of inner plates coupled to the shaft, and a plurality of outer plates, coupled to the case body, which are arranged in the working chamber in such a manner as to be spaced apart from the inner plates with a pitch in an axial direction of the shaft. The pitch between each of the inner plates and each of the outer plates is adjustable by deforming either of the inner plates and the outer plates in response to the rotation speed of the shaft or the case body.

    摘要翻译: 粘性联轴器包括用于形成包含粘性流体的工作室的壳体主体,以相对于壳体相对旋转的方式插入到壳体中的轴;多个内板, 轴和多个外板,其连接到壳体,它们以与轴的轴向方向间隔开的方式设置在工作室中。 每个内板和每个外板之间的间距可通过根据轴或壳体的旋转速度使内板和外板之一变形来调节。

    Compressor having a seal member for supporting a shaft during assembly

    公开(公告)号:US06565340B2

    公开(公告)日:2003-05-20

    申请号:US09984143

    申请日:2001-10-29

    IPC分类号: F04C1804

    摘要: A compressor assembled under desirable working conditions at a low cost is disclosed. In the compressor, the first rolling bearing for permitting axial movement of the shaft is inserted into the first housing from the side where the compression mechanism is to be provided, and the second rolling bearing for restricting axial movement of the shaft is inserted into the first housing from the other side where the driving source is to be provided. The shaft is inserted into the first housing from the side where the compression mechanism is to be provided. A seal member is further provided between the rolling bearings for sealing an area between the insertion hole and the shaft, wherein the seal member is inserted into the insertion hole of the first housing from the side where the compression mechanism is to be provided before the shaft is inserted into the insertion hole.

    DIGITAL CAMERA AND INTERCHANGEABLE LENS UNIT
    9.
    发明申请
    DIGITAL CAMERA AND INTERCHANGEABLE LENS UNIT 有权
    数码相机和可互换镜头单元

    公开(公告)号:US20110317062A1

    公开(公告)日:2011-12-29

    申请号:US13254016

    申请日:2011-01-13

    IPC分类号: H04N5/225 G03B17/00

    摘要: A circuit board is arranged on an end face of a lens barrel on a lens mount side and installed with an electronic circuit device, a plurality of connection terminals which are arranged in an electrically insulating state in the lens mount and serve to connect the electronic circuit device on the circuit board with an electronic circuit device inside a camera body, and a wiring member is for connecting the plurality of connection terminals with the circuit board, where the wiring member is provided with a ground connection section which is connected to a ground pattern of the circuit board and also electrically connected to a connection terminal that is to be a ground terminal among the plurality of connection terminals, and an extended wiring pattern is for electrically grounding the ground connection section on a metal portion of the lens mount.

    摘要翻译: 电路板布置在透镜安装侧的透镜镜筒的端面上,并安装有电子电路装置,多个连接端子,其以电绝缘状态布置在透镜安装件中,并用于连接电子电路 具有电子电路装置的电路板上的装置,以及布线部件,用于将多个连接端子与电路基板连接,其中布线部件设置有接地连接部,该接地连接部连接到接地图案 并且还与多个连接端子中的作为接地端子的连接端子电连接,并且延长的布线图案用于将透镜安装件的金属部分上的接地连接部分电接地。