摘要:
Provided are compounds represented by the following formula (A-1) and formula (1), or salts thereof. The compounds of formula (A-1) and formula (1) or salts thereof have β3 adrenergic receptor agonist activity, and thus are useful as therapeutic and prophylactic agent for diabetes mellitus, obesity, hyperlipidemia, depression, diseases caused by gallstones or hypermotility of the biliary tract, diseases caused by hyperactivity of the digestive tract, interstitial cystitis, overactive bladder or urinary incontinence, or as therapeutic and prophylactic agents for diseases concomitant with decreased tears.
摘要:
Provided are compounds represented by the following formula (A-1) and formula (1), or salts thereof. The compounds of formula (A-1) and formula (1) or salts thereof have 133 adrenergic receptor agonist activity, and thus are useful as therapeutic and prophylactic agent for diabetes mellitus, obesity, hyperlipidemia, depression, diseases caused by gallstones or hypermotility of the biliary tract, diseases caused by hyperactivity of the digestive tract, interstitial cystitis, overactive bladder or urinary incontinence, or as therapeutic and prophylactic agents for diseases concomitant with decreased tears.
摘要:
Compounds represented by the Formula (A-1) and the Formula (1) or salt thereof are provided. The compounds represented by the Formula (A-1) and the Formula (1) or salt thereof have a β3 adrenergic receptor agonist activity, and therefore are useful as an agent for the prevention and treatment of diabetes, obesity, hyperlipidemia, depression, biliary stone, a disorder derived from hyperactivity of biliary tract, a disorder derived from hyperactivity of digestive tract, interstitial cystitis, overactive bladder, urinary incontinence or a disorder derived from decreased tear secretion, etc.
摘要:
[Objective] To provide a drug that selectively stimulates the β3-adrenergic receptors, particularly a drug capable of preferentially stimulating the β3-adrenergic receptors over the α1-adrenergic receptors. This drug can be used in the treatment and prevention of diabetes, obesity, hyperlipidemia, depression, cholelithiasis, diseases caused by biliary hyperkinesia, diseases caused by hyperfunction of the gastrointestinal tract, interstitial cystitis, overactive bladder or urinary incontinence, diseases associated with decreased lacrimation, and the like.[Solution] Indazole analogs represented by the general formula (I) or a salt thereof. Drugs that contains these indazole analogs or a salt thereof as the active ingredient.
摘要:
A viscous coupling includes a case body for forming a working chamber which contains the viscous fluid, a shaft inserted into the case body in such a manner that the shaft is relatively rotatable with respect to the case body, a plurality of inner plates coupled to the shaft, and a plurality of outer plates, coupled to the case body, which are arranged in the working chamber in such a manner as to be spaced apart from the inner plates with a pitch in an axial direction of the shaft. The pitch between each of the inner plates and each of the outer plates is adjustable by deforming either of the inner plates and the outer plates in response to the rotation speed of the shaft or the case body.
摘要:
A compressor assembled under desirable working conditions at a low cost is disclosed. In the compressor, the first rolling bearing for permitting axial movement of the shaft is inserted into the first housing from the side where the compression mechanism is to be provided, and the second rolling bearing for restricting axial movement of the shaft is inserted into the first housing from the other side where the driving source is to be provided. The shaft is inserted into the first housing from the side where the compression mechanism is to be provided. A seal member is further provided between the rolling bearings for sealing an area between the insertion hole and the shaft, wherein the seal member is inserted into the insertion hole of the first housing from the side where the compression mechanism is to be provided before the shaft is inserted into the insertion hole.
摘要:
The present invention provides an insecticidal composition comprising, as active ingredients, (a) at least one pyrethroid compound and (b) an N-arylpyrazole compound such as 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylsulfmylpyrazole, and an insecticidal method which comprises applying the composition.
摘要:
Aldehydes are produced by reacting an olefinic compound with carbon monoxide and hydrogen in the presence of a catalyst containing a metal of Group 8 to 10 and a phosphonite compound as a trivalent organic phosphorus compound.
摘要:
A circuit board is arranged on an end face of a lens barrel on a lens mount side and installed with an electronic circuit device, a plurality of connection terminals which are arranged in an electrically insulating state in the lens mount and serve to connect the electronic circuit device on the circuit board with an electronic circuit device inside a camera body, and a wiring member is for connecting the plurality of connection terminals with the circuit board, where the wiring member is provided with a ground connection section which is connected to a ground pattern of the circuit board and also electrically connected to a connection terminal that is to be a ground terminal among the plurality of connection terminals, and an extended wiring pattern is for electrically grounding the ground connection section on a metal portion of the lens mount.
摘要:
There is provided an information recording and reproducing method and an apparatus for the same capable of optimizing the shift adjustment of a recording pulse recorded in an optical disk even at the time of recording information on the optical disk at a high speed. The shift adjustment value of the recording pulse optimized at a low speed recording on an optical disk is multiplied by a constant value to be taken as the optimum shift conditions of the recording pulse at the high speed recording.