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    Biopsy device with inner cutting member
    1.
    发明申请
    Biopsy device with inner cutting member 有权
    内切割活检装置

    公开(公告)号：US20040167428A1

    公开(公告)日：2004-08-26

    申请号：US10642406

    申请日：2003-08-15

    申请人： SenoRx, Inc.

    发明人： Richard L. Quick ,  Frank R. Louw ,  Paul Lubock ,  Martin V. Shabaz

    IPC分类号： A61B010/00

    CPC分类号： A61B10/0233 ,  A61B10/02 ,  A61B10/0266 ,  A61B10/0275 ,  A61B10/0283 ,  A61B17/32002 ,  A61B17/3417 ,  A61B90/30 ,  A61B90/39 ,  A61B2010/0208 ,  A61B2010/0225 ,  A61B2017/0046 ,  A61B2017/00473 ,  A61B2017/3405 ,  A61B2017/3454 ,  A61B2090/0811 ,  A61B2090/309 ,  B23Q17/2404 ,  F21V33/0068

    摘要： The invention is directed to devices and methods for separating and collecting a tissue specimen from a patient's target site. The device includes a probe member with a penetrating distal tip and a tissue receiving aperture, and a tissue cutting member which is rotatable disposed within the probe member to cut a tissue specimen drawn into the interior of the device through the aperture. The longitudinal edges of the aperture are preferably sharpened to engage the cutting edges of the tissue cutting member. Vacuum may be provided in the inner lumen of the cutting member to transport tissue therethrough. Rotation, rotational oscillation and/or longitudinal reciprocation of the tissue cutting member is effective to separate a tissue specimen from surrounding tissue. An accessing cannula having an tissue receiving aperture may be concentrically disposed within the probe member and about the tissue cutting member. The tissue cutting edge of the tissue cutting member preferably is longitudinally oriented and may have a cutting angle less than 90null with respect to the longitudinal axis of the tissue cutting member.

    摘要翻译： 本发明涉及用于从患者的目标部位分离和收集组织标本的装置和方法。 该装置包括具有穿透性远侧末端和组织接收孔的探针构件，以及组织切割构件，该组织切割构件可旋转地设置在探针构件内，以通过孔切割被拉入装置内部的组织样本。 孔的纵向边缘优选地被锐化以接合组织切割构件的切割边缘。 可以在切割构件的内腔中设置真空以将组织输送通过其中。 组织切割构件的旋转，旋转振动和/或纵向往复运动有效地将组织标本与周围组织分开。 具有组织接收孔的进入套管可以同心地设置在探针构件内并且围绕组织切割构件。 组织切割构件的组织切割边缘优选地纵向定向并且可以具有相对于组织切割构件的纵向轴线小于90°的切割角度。

    Biopsy device with inner cutter
    2.
    发明申请
    Biopsy device with inner cutter 有权
    内切刀活检装置

    公开(公告)号：US20040167427A1

    公开(公告)日：2004-08-26

    申请号：US10374915

    申请日：2003-02-24

    申请人： SenoRx, Inc.

    发明人： Richard L. Quick ,  Frank Louw ,  Paul Lubock ,  Martin V. Shabaz

    IPC分类号： A61B010/00

    CPC分类号： A61B10/0233 ,  A61B10/02 ,  A61B10/0266 ,  A61B10/0275 ,  A61B10/0283 ,  A61B17/32002 ,  A61B17/3417 ,  A61B90/30 ,  A61B90/39 ,  A61B2010/0208 ,  A61B2010/0225 ,  A61B2017/0046 ,  A61B2017/00473 ,  A61B2017/3405 ,  A61B2017/3454 ,  A61B2090/0811 ,  A61B2090/309 ,  B23Q17/2404 ,  F21V33/0068

    摘要： The invention is directed to devices and methods for accessing a desired target site within a patient's body and for separating and collecting a tissue specimen from the target site. The device includes a probe member or cannula with a penetrating distal tip, and a tissue cutting member which is disposed within the probe member to cut a tissue specimen from supporting tissue at the biopsy site. This probe is releasably secured to a housing to provide a plurality of discrete orientations of the probe about its longitudinal axis. Vacuum may be provided to the inner lumen of the cutting member to transport tissue through the inner lumen thereof. Rotation (and optionally longitudinal reciprocation) of the tissue cutter is effective to separate a tissue specimen from surrounding tissue at the target site. Vacuum or fluid pressure may be used to move the specimen cut from the target site proximally within the inner lumen defined at least in part by the cutting member for collection. An elongated accessing cannula having an tissue receiving aperture communicating with an inner lumen of the accessing cannula, may be provided with the device and is preferably concentrically disposed within the probe member and about the tissue cutter. The tissue cutting surface of the tissue cutter preferably is longitudinally oriented and may be at an angle with respect to the longitudinal axis of the tissue cutter.

    摘要翻译： 本发明涉及用于访问患者体内期望的目标部位并用于从目标部位分离和收集组织标本的装置和方法。 该装置包括具有穿透性远侧末端的探针构件或套管，以及组织切割构件，其设置在探针构件内以从活组织检查部位的支撑组织切割组织样本。 该探针可释放地固定到壳体以提供探针围绕其纵向轴线的多个离散定向。 可以向切割构件的内腔提供真空以将组织输送通过其内腔。 组织切割器的旋转（和任选的纵向往复运动）有效地将组织标本与目标部位的周围组织分离。 可以使用真空或流体压力来将从目标位置切割的样本移动到至少部分地由切割构件限定的内腔内用于收集。 具有与进入插管的内腔连通的组织接收孔的细长进入套管可以设置有该装置，并且优选地同心地设置在探针构件内并且围绕组织切割器。 组织切割器的组织切割表面优选地纵向定向并且可以相对于组织切割器的纵向轴线成一定角度。

    Tissue specimen encapsulation device and method thereof
    3.
    发明申请
    Tissue specimen encapsulation device and method thereof 有权
    组织标本包封装置及其方法

    公开(公告)号：US20030176812A1

    公开(公告)日：2003-09-18

    申请号：US10342867

    申请日：2003-01-14

    申请人： SenoRx, Inc.

    发明人： Fred H. Burbank ,  Richard L. Quick ,  Jacob Frank Louw ,  Michael L. Jones ,  Paul Lubock

    IPC分类号： A61B010/00

    CPC分类号： A61B10/0266 ,  A61B10/02 ,  A61B17/00234 ,  A61B17/221 ,  A61B17/32056 ,  A61B17/320725 ,  A61B17/3417 ,  A61B18/14 ,  A61B18/1487 ,  A61B18/1492 ,  A61B90/37 ,  A61B2017/00287 ,  A61B2017/2212 ,  A61B2017/320064 ,  A61B2018/00214 ,  A61B2018/00267 ,  A61B2018/00333 ,  A61B2018/00898 ,  A61B2018/0091 ,  A61B2018/00916 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1407 ,  A61B2018/1475 ,  A61B2018/162 ,  A61B2090/3908

    摘要： A device for encapsulating tissue specimens includes a wand assembly, a sheath, and a guide assembly. The guide assembly pulls, draws, or otherwise moves the sheath about the tissue specimen. The wand assembly is disposed proximate to the tissue specimen, typically either adjacent or through the specimen. In an aspect of the encapsulating device, the The guide assembly has sheath deployment members that are disposed about the tissue specimen. The sheath, which is attached to ends of the sheath deployment members and the wand assembly, is drawn over the tissue specimen as the sheath deployment members are pushed or pulled. In another aspect of the device, the guide assembly is an arm or a housing that rotates about the tissue specimen. The sheath, which is secured at one end to the guide assembly and at another end to the wand assembly, is drawn over the tissue specimen as the guide assembly rotates. The sheath may be made up of porous material, non-porous material, selectively permeable material, woven material, braided material, knit material, web material, mesh material, a film material, a flexible laminate material, or of an elastic material.

    摘要翻译： 用于封装组织样本的装置包括棒组件，护套和引导组件。 引导组件拉动，牵引或以其他方式使护套围绕组织标本移动。 棒组件靠近组织标本设置，通常是相邻的或通过样本。 在封装装置的一个方面，引导组件具有围绕组织标本设置的护套展开部件。 当护套展开构件被推动或拉动时，附接到鞘展开构件和杆组件的端部的护套被拉过组织标本。 在装置的另一方面，导向组件是围绕组织标本旋转的臂或壳体。 当引导组件旋转时，在一端固定到引导组件并且另一端固定到杆组件的护套在组织样本上被拉伸。 护套可以由多孔材料，无孔材料，选择性渗透材料，编织材料，编织材料，针织材料，纤维网材料，网状材料，薄膜材料，柔性层压材料或弹性材料制成。

    Electrosurgical lesion location device
    6.
    发明申请
    Electrosurgical lesion location device 有权

    公开(公告)号：US20020077628A1

    公开(公告)日：2002-06-20

    申请号：US09967755

    申请日：2001-09-28

    申请人： SenoRx, Inc.

    发明人： Fred H. Burbank ,  Frank R. Louw ,  Paul Lubock ,  Richard L. Quick

    IPC分类号： A61B018/14

    CPC分类号： A61B10/0266 ,  A61B10/02 ,  A61B17/00491 ,  A61B17/32056 ,  A61B17/320725 ,  A61B17/3417 ,  A61B18/14 ,  A61B18/1477 ,  A61B18/1487 ,  A61B18/1492 ,  A61B90/17 ,  A61B90/37 ,  A61B90/39 ,  A61B2017/3488 ,  A61B2018/00208 ,  A61B2018/00214 ,  A61B2018/00267 ,  A61B2018/00333 ,  A61B2018/00577 ,  A61B2018/00898 ,  A61B2018/0091 ,  A61B2018/00916 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1407 ,  A61B2018/1425 ,  A61B2018/1475 ,  A61B2018/162 ,  A61B2090/3908

    摘要： A device for localizing a target tissue mass in a body includes a tubular trocar portion having a distal end and a proximal end portion that is removably attachable to a handle portion. The trocar portion contains at least a first plurality of locator wires that are movable between a retracted position within the trocar and a deployed position extending radially from the trocar. In a preferred embodiment, the trocar portion has an electrosurgical cutting element at its distal end, and first and second pluralities of locator wires that, when deployed, respectively define first and second locating perimeters. The first plurality of locator wires is connected to a first wire-carrying member longitudinally mounted for axial movement within the trocar portion between a proximal position corresponding to the retracted position of the first plurality of locator wires, and a distal position corresponding to the deployed position of the first plurality of locator wires. The second plurality of locator wires is connected to a second wire-carrying member longitudinally mounted in the trocar portion, coaxially with the first tubular member, for movement between a distal position corresponding to the retracted position of the second plurality of locator wires, and a proximal position corresponding to the deployed position of the second plurality of locator wires. The trocar portion has an intermediate portion having first and second pluralities of slot-shaped apertures through which the first and second pluralities of locator wires emerge when moved to their respective deployed positions. With the locator wires in their retracted position, the trocar is passed through a target tissue mass until the intermediate portion is within the mass. The locator wires are then deployed within the mass to anchor the trocar therein and to mark the site for a surgical procedure. In the preferred embodiment, the locator wires are electrically energized to facilitate their deployment electrosurgically.

    Shapeable electrosurgical scalpel
    8.
    发明申请
    Shapeable electrosurgical scalpel 有权
    可锻电刀手术刀

    公开(公告)号：US20040030334A1

    公开(公告)日：2004-02-12

    申请号：US10446507

    申请日：2003-05-27

    申请人： SenoRx, Inc.

    发明人： Richard L. Quick ,  Martin Shabaz ,  Dan Kussman ,  Paul Lubock

    IPC分类号： A61B018/14

    CPC分类号： A61B17/32002 ,  A61B10/0266 ,  A61B18/14 ,  A61B18/1402 ,  A61B2018/00208 ,  A61B2018/00601 ,  A61B2018/1405 ,  A61B2018/1407 ,  A61B2018/1861

    摘要： The invention is directed to an electrosurgical device having a shapeable elongate cutting electrode having a free distal end with an exposed length of at least 0.5 inch and secured by its proximal end to the distal end of a handle. The electrosurgical device is designed for use with a high frequency electrosurgical generator which has an output at a frequency of between about 1 MHz and about 10 MHz, preferably about 3 to about 8 MHz. Preferably, the output has an essentially sinusoidal waveform with little harmonic distortion. The methods provide for the enhanced cutting of a variety of tissue including muscular, connective, glandular and fatty tissue. The device is particularly suitable in performing a breast biopsy.

    摘要翻译： 本发明涉及一种具有可成形的细长切割电极的电外科装置，其具有自由远端，其暴露长度至少为0.5英寸，并通过其近端固定到手柄的远端。 电外科设备设计用于高频电外科发生器，其具有在约1MHz至约10MHz之间，优选约3至约8MHz的频率的输出。 优选地，输出具有几乎没有谐波失真的基本正弦波形。 该方法提供了增强切割各种组织，包括肌肉，结缔，腺体和脂肪组织。 该装置特别适用于进行乳腺活检。

    Electrosurgical biopsy device and method
    9.
    发明申请
    Electrosurgical biopsy device and method 有权
    电外科活检装置及方法

    公开(公告)号：US20010014779A1

    公开(公告)日：2001-08-16

    申请号：US09819185

    申请日：2001-03-27

    申请人： SenoRx, Inc.

    发明人： Fred H. Burbank ,  Paul Lubock ,  Michael L. Jones ,  Richard L. Quick

    IPC分类号： A61B010/00

    CPC分类号： A61B10/0266 ,  A61B10/02 ,  A61B17/00491 ,  A61B17/32056 ,  A61B17/320725 ,  A61B17/3417 ,  A61B18/14 ,  A61B18/1487 ,  A61B18/1492 ,  A61B90/17 ,  A61B90/37 ,  A61B2010/0208 ,  A61B2017/3488 ,  A61B2018/00208 ,  A61B2018/00214 ,  A61B2018/00267 ,  A61B2018/00333 ,  A61B2018/00898 ,  A61B2018/0091 ,  A61B2018/00916 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1407 ,  A61B2018/1475 ,  A61B2018/162 ,  A61B2090/3908

    摘要： An electrosurgical biopsy device includes a stylet and a cannula movably mounted on a base. The stylet has a shaft with a head at its distal end and a stylet ablation element extending distally from the head. The stylet shaft is disposed through the cannula for axial translation therein between withdrawn and extended positions. The cannula has an opening at its distal end and a cannula ablation element adjacent the opening. Both ablation elements are activatable with energy that ablates adjacent tissue. A translation mechanism controllably moves (a) the stylet between the withdrawn and extended positions and (b) the cannula between a proximal position and a distal position relative to the base. In use, with the stylet in the withdrawn position against the distal end of the cannula, and with the stylet ablation element activated, the stylet and the cannula are pushed through the skin and the underlying tissue until the stylet head is adjacent a targeted tissue mass. Next, the stylet is extended distally from the distal end of the cannula so that its head penetrates the tissue mass. The cannula ablation element is then activated, and the cannula is pushed through the tissue mass toward the stylet head, thereby cutting a nullcorenull through the tissue mass that is captured as a tissue specimen within the distal end of the cannula. The cannula and the stylet are then removed from the patient's body.

    摘要翻译： 电外科活检装置包括探针和可移动地安装在基座上的套管。 探针具有在其远端具有头部的轴和从头部向远侧延伸的探针消融元件。 探针轴穿过套管设置，用于在撤回位置和伸出位置之间进行轴向平移。 套管在其远端具有开口，并且在开口附近具有插管消融元件。 两种消融元件都可以通过消融相邻组织的能量来激活。 平移机构可以可控地移动（a）探针和延伸位置之间的探针，（b）相对于基部的近端位置和远端位置之间的插管。 在使用中，探针的位置靠近插管的远端，并且在探针探针元件被激活时，探针和套管被推到皮肤和下面的组织上，直到探针头与目标组织块相邻 。 接下来，探针从套管的远端向远端延伸，使得其头部穿透组织块。 插管消融元件然后被激活，并且套管被推动通过组织块朝向管心针头，从而通过作为套管远端内的组织样本捕获的组织块切割“芯”。 然后将套管和探针从患者身体移除。

    Tissue site markers for in vivo imaging
    10.
    发明申请
    Tissue site markers for in vivo imaging 有权
    用于体内成像的组织位点标记

    公开(公告)号：US20040193044A1

    公开(公告)日：2004-09-30

    申请号：US10823053

    申请日：2004-04-12

    申请人： SenoRx, Inc.

    发明人： Fred H. Burbank ,  Paul Lubock ,  Michael L. Jones ,  Richard L. Quick ,  Frank Louw ,  Stephen A. De Santis

    IPC分类号： A61B006/00

    CPC分类号： A61M37/0069 ,  A61B6/12 ,  A61B8/0833 ,  A61B10/02 ,  A61B90/39 ,  A61B2017/00004 ,  A61B2090/08021 ,  A61B2090/3908 ,  A61B2090/3925 ,  A61B2090/3987 ,  A61K49/006 ,  A61K49/222

    摘要： The invention is directed biopsy site markers and methods of marking a biopsy site, so that the location of the biopsy cavity is readily visible by conventional imaging methods, particularly by ultrasonic imaging. The biopsy site markers of the invention have high ultrasound reflectivity, presenting a substantial acoustic signature from a small marker, so as to avoid obscuring diagnostic tissue features in subsequent imaging studies, and can be readily distinguished from biological features. The several disclosed embodiments of the biopsy site marker of the invention have a high contrast of acoustic impedance as placed in a tissue site, so as to efficiently reflect and scatter ultrasonic energy, and preferably include gas-filled internal pores. The markers may have a non-uniform surface contour to enhance the acoustic signature. The markers have a characteristic form which is recognizably artificial during medical imaging. The biopsy site marker may be accurately fixed to the biopsy site so as to resist migration from the biopsy cavity when a placement instrument is withdrawn, and when the marked tissue is subsequently moved or manipulated.

    摘要翻译： 本发明涉及活检部位标记和标记活组织检查部位的方法，使得活检腔的位置通过常规成像方法，特别是通过超声成像容易看到。 本发明的活检部位标记物具有高的超声反射率，从小标记物呈现出实质的声学特征，以避免在随后的成像研究中掩盖诊断组织特征，并且可以容易地与生物特征区别开来。 本发明的活检部位标记物的几个公开的实施方案具有放置在组织部位中的声阻抗的高对比度，以便有效地反射和散射超声能量，并且优选地包括气体填充的内部孔。 标记可以具有不均匀的表面轮廓以增强声学特征。 标记具有在医学成像期间可识别人造的特征形式。 可以将活检部位标记物精确地固定到活检部位，以便当放置放置器械被取出时以及随后移动或操纵标记的组织时抵抗活组织腔的迁移。