公开(公告)号：US20240401140A1

公开(公告)日：2024-12-05

申请号：US18800497

申请日：2024-08-12

Applicant: Sequenom, Inc.

Inventor： Charles R. Cantor ,  Grace DeSantis ,  Reinhold Mueller ,  Mathias Ehrich

IPC: C12Q1/6883 ,  C07K16/18 ,  C12Q1/6804

Abstract: Technology provided herein relates in part to methods, processes and apparatuses for non-invasive assessment of genetic variations.

公开(公告)号：US10557164B2

公开(公告)日：2020-02-11

申请号：US14488757

申请日：2014-09-17

Applicant: SEQUENOM, INC.

Inventor： Charles R. Cantor

IPC: C12Q1/6818 ,  C12Q1/6816 ,  C12Q1/6869

Abstract: Provided herein are compositions and methods for analysis of nucleic acids, including, methods and compositions for genotyping, haplotyping, sequencing and performing other genetic and epigenetic analyses on nucleic acids, for example. In some embodiments, methods and compositions suitable for whole-genome sequencing on single molecules of nucleic acid are provided. In some embodiments, analysis of single molecules of nucleic acid are performed in conjunction with nanopores and/or nanopore devices.

公开(公告)号：US20240150833A1

公开(公告)日：2024-05-09

申请号：US18327087

申请日：2023-06-01

Applicant: Sequenom, Inc.

Inventor： Charles R. Cantor

IPC: C12Q1/6876 ,  C12Q1/6806 ,  C12Q1/6837 ,  C12Q1/6844

CPC classification number: C12Q1/6876 ,  C12Q1/6806 ,  C12Q1/6837 ,  C12Q1/6844

Abstract: Improved solid supports and methods for analyzing target nucleotide sequences are provided herein. Certain improvements are directed to efficiently preparing nucleic acids that comprise nucleotide sequences identical to or substantially identical to one or more target nucleotide sequences, or complement thereof. The prepared nucleic acids include a reference sequence that facilitates sequence analysis. The solid supports and methods provided herein minimize the number of steps required by published sequence analysis methodologies, and thereby offer improved sequence analysis efficiency.

公开(公告)号：US20220356523A1

公开(公告)日：2022-11-10

申请号：US17704296

申请日：2022-03-25

Applicant: Sequenom, Inc.

Inventor： Charles R. Cantor ,  Grace DeSantis ,  Reinhold Mueller ,  Mathias Ehrich

IPC: C12Q1/6883 ,  C07K16/18 ,  C12Q1/6804

Abstract: Technology provided herein relates in part to methods, processes and apparatuses for non-invasive assessment of genetic variations.

公开(公告)号：US10738359B2

公开(公告)日：2020-08-11

申请号：US15443051

申请日：2017-02-27

Applicant: SEQUENOM, INC.

Inventor： Charles R. Cantor ,  Grace DeSantis ,  Reinhold Mueller ,  Mathias Ehrich

IPC: C12Q1/68 ,  C12Q1/6883 ,  C07K16/18 ,  C12Q1/6804

Abstract: Technology provided herein relates in part to methods, processes and apparatuses for non-invasive assessment of genetic variations.

公开(公告)号：US11708607B2

公开(公告)日：2023-07-25

申请号：US16912041

申请日：2020-06-25

Applicant: Sequenom, Inc.

Inventor： Charles R. Cantor

IPC: C12Q1/6876 ,  C12Q1/6806 ,  C12Q1/6844 ,  C12Q1/6837

CPC classification number: C12Q1/6876 ,  C12Q1/6806 ,  C12Q1/6837 ,  C12Q1/6844 ,  C12Q1/6806 ,  C12Q2565/537 ,  C12Q2565/519 ,  C12Q2565/501 ,  C12Q1/6837 ,  C12Q2531/101 ,  C12Q2525/161 ,  C12Q2525/155 ,  C12Q1/6844 ,  C12Q2565/537 ,  C12Q2565/519 ,  C12Q2565/501

Abstract: Improved solid supports and methods for analyzing target nucleotide sequences are provided herein. Certain improvements are directed to efficiently preparing nucleic acids that comprise nucleotide sequences identical to or substantially identical to one or more target nucleotide sequences, or complement thereof. The prepared nucleic acids include a reference sequence that facilitates sequence analysis. The solid supports and methods provided herein minimize the number of steps required by published sequence analysis methodologies, and thereby offer improved sequence analysis efficiency.

公开(公告)号：US11001884B2

公开(公告)日：2021-05-11

申请号：US15647148

申请日：2017-07-11

Applicant: SEQUENOM, INC.

Inventor： Dirk Johannes Van Den Boom ,  Charles R. Cantor ,  Sung Kyun Kim ,  Zeljko Dzakula ,  Cosmin Deciu

IPC: C12Q1/6869 ,  G16B20/00 ,  C12Q1/6827 ,  G16B30/00 ,  G16B40/00

Abstract: Technology provided herein relates in part to methods, processes and apparatuses for non-invasive assessment of genetic variations.

公开(公告)号：US10731213B2

公开(公告)日：2020-08-04

申请号：US14973467

申请日：2015-12-17

Applicant: SEQUENOM, INC.

Inventor： Charles R. Cantor

IPC: C12Q1/68 ,  C12Q1/6876 ,  C12Q1/6806 ,  C12Q1/6844 ,  C12Q1/6837

Abstract: Improved solid supports and methods for analyzing target nucleotide sequences are provided herein. Certain improvements are directed to efficiently preparing nucleic acids that comprise nucleotide sequences identical to or substantially identical to one or more target nucleotide sequences, or complement thereof. The prepared nucleic acids include a reference sequence that facilitates sequence analysis. The solid supports and methods provided herein minimize the number of steps required by published sequence analysis methodologies, and thereby offer improved sequence analysis efficiency.

公开(公告)号：US09605313B2

公开(公告)日：2017-03-28

申请号：US13782901

申请日：2013-03-01

Applicant: SEQUENOM, INC.

Inventor： Charles R. Cantor ,  Grace DeSantis ,  Reinhold Mueller ,  Mathias Ehrich

IPC: C12P19/34 ,  C12Q1/68 ,  C07K16/18

CPC classification number: C12Q1/6883 ,  C07K16/18 ,  C12Q1/6804 ,  C12Q2522/101

Abstract: Technology provided herein relates in part to methods, processes and apparatuses for non-invasive assessment of genetic variations.

公开(公告)号：US11312997B2

公开(公告)日：2022-04-26

申请号：US16884528

申请日：2020-05-27

Applicant: Sequenom, Inc.

Inventor： Charles R. Cantor ,  Grace DeSantis ,  Reinhold Mueller ,  Mathias Ehrich

IPC: C12Q1/6883 ,  C07K16/18 ,  C12Q1/6804

Abstract: Technology provided herein relates in part to methods, processes and apparatuses for non-invasive assessment of genetic variations.