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公开(公告)号：US5674284A
公开(公告)日：1997-10-07
申请号：US605454
申请日：1996-02-26
CPC分类号： B29D11/023 , B29C43/02 , A61F2002/1683 , B29C2793/009 , B29C43/00 , B29K2033/12 , B29K2105/255 , B29K2995/0053 , B29K2995/0064 , B29L2011/0016 , Y10S425/808
摘要： The polymethyl methacrylate (PMMA) or copolymer thereof used to produce one-piece intraocular lenses is modified by a compression molding process to produce a much tougher material with improved mechanical properties. The process takes material in rod form and compresses into lens blanks. The molded lens blanks receive little or no compression strain in the center 4 mm optic zone. The compression is limited to the periphery region outside the center 4 mm zone. The intraocular lens fabricated from the molded lens blank exhibits greatly increased haptic mechanical properties and resistance to breakage.
摘要翻译： 用于制造单件眼内透镜的聚甲基丙烯酸甲酯（PMMA）或其共聚物通过压缩模塑方法进行改性，以产生具有改善的机械性能的更坚韧的材料。 该过程采用棒状材料并压缩成镜片坯料。 模制的透镜毛坯在中心4 mm光学区域几乎没有受到压缩应变。 压缩限制在中心4 mm区域外的周边区域。 由模制的透镜毛坯制造的眼内透镜显示出大大增加的触觉机械性能和抗断裂性。
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公开(公告)号：US5895610A
公开(公告)日：1999-04-20
申请号：US940676
申请日：1997-09-30
CPC分类号： B29D11/023 , B29C43/02 , A61F2002/1683 , B29C2793/009 , B29C43/00 , B29K2033/12 , B29K2105/255 , B29K2995/0053 , B29K2995/0064 , B29L2011/0016 , Y10S425/808
摘要： The polymethyl methacrylate (PMMA) or copolymer thereof used to produce one-piece intraocular lenses is modified by a compression molding process to produce a much tougher material with improved mechanical properties. The process takes material in rod form and compresses into lens blanks. The molded lens blanks receive little or no compression strain in the center 4 mm optic zone. The compression is limited to the periphery region outside the center 4 mm zone. The intraocular lens fabricated from the molded lens blank exhibits greatly increased haptic mechanical properties and resistance to breakage.
摘要翻译： 用于制造单件眼内透镜的聚甲基丙烯酸甲酯（PMMA）或其共聚物通过压缩模塑方法进行改性，以产生具有改善的机械性能的更坚韧的材料。 该过程采用棒状材料并压缩成镜片坯料。 模制的透镜毛坯在中心4 mm光学区域几乎没有受到压缩应变。 压缩限制在中心4 mm区域外的周边区域。 由模制的透镜毛坯制造的眼内透镜显示出大大增加的触觉机械性能和抗断裂性。
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公开(公告)号：US5582778A
公开(公告)日：1996-12-10
申请号：US299231
申请日：1994-08-31
CPC分类号： A61F2/16 , B29D11/023 , A61F2002/1686 , B29C2793/009
摘要： An improved intraocular lens has at least one filamentary haptic composed of a continuous matrix material interspersed with a toughening amount of discrete particles of a multistage, sequentially produced elastomeric polymer. An improved process for preparing a single-piece intraocular lens involves preparing a composite lens blank by molding pellets composed of a continuous polymeric material interspersed with particles of a multistage, sequentially produced elastomeric polymer about a central optic lens core so as to produce a single lens blank having a toughened annular region surrounding the central optic region, and then machining at least one filamentary haptic from the toughened annular region to prepare the lens.
摘要翻译： 改进的眼内透镜具有至少一个丝状触觉体，其由连续基质材料组成，该连续基质材料散布有增韧量的多级顺序制备的弹性体聚合物的离散颗粒。 用于制备单件眼内透镜的改进方法包括通过模制由连续的聚合物材料构成的颗粒来制备复合透镜坯料，该连续聚合材料散布有围绕中心光学透镜芯的多级顺序制备的弹性体聚合物的颗粒，以产生单个透镜 坯件具有围绕中心光学区域的钢化环形区域，然后从钢化环形区域加工至少一个丝状触觉件以制备透镜。
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公开(公告)号：US5282853A
公开(公告)日：1994-02-01
申请号：US953406
申请日：1992-09-29
CPC分类号： A61F2/16 , B29D11/023 , A61F2002/1686 , B29C2793/009
摘要： An improved intraocular lens is disclosed with at least one filamentary haptic composed of a continuous matrix material interspersed with a toughening amount of discrete particles of a multistage, sequentially produced elastomeric polymer. An improved process for preparing a single-piece intraocular lens is also disclosed. The process involves preparing a composite lens blank by molding pellets composed of a continuous polymeric material interspersed with particles of a multistage, sequentially produced elastomeric polymer about a central optic lens core so as to produce a single lens blank having a toughened annular region surrounding the central optic region, and then machining at least one filamentary haptic from the toughened annular region to prepare the lens.
摘要翻译： 公开了一种改进的眼内透镜，其具有由连续基质材料组成的至少一个丝状触觉物，所述连续基质材料散布有增韧量的多级顺序制备的弹性体聚合物的离散颗粒。 还公开了一种用于制备单片人工晶状体的改进方法。 该方法包括通过将由连续聚合材料构成的颗粒制成复合透镜坯料，该连续聚合材料散布有围绕中心光学透镜芯的多级顺序制备的弹性体聚合物的颗粒，以便产生具有围绕中心的增韧环形区域的单一透镜坯料 光学区域，然后从韧化的环形区域加工至少一个丝状触觉件以制备透镜。
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公开(公告)号：US20100076554A1
公开(公告)日：2010-03-25
申请号：US12628344
申请日：2009-12-01
CPC分类号： A61F2/1624 , A61F2/1618 , A61F2/1627 , A61F2/1635 , A61L27/18 , A61L2430/16 , G02B1/043 , G02C7/06 , G02C2202/14 , C08L83/04
摘要： The invention relates to novel intraocular lenses. The lenses are capable of post-operative adjustment of their optical properties, including conversion from single focal lenses to multifocal lenses.
摘要翻译： 本发明涉及新型眼内透镜。 透镜能够对其光学性能进行术后调整，包括从单焦点透镜转换为多焦点透镜。
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公开(公告)号：US09713527B2
公开(公告)日：2017-07-25
申请号：US11489847
申请日：2006-07-20
申请人： Okihiro Nishi , Kayo Nishi , Shiao H. Chang , Jerry Kaeni
发明人： Okihiro Nishi , Kayo Nishi , Shiao H. Chang , Jerry Kaeni
CPC分类号： A61F2/1648 , A61F2/1613 , A61F2/1627 , A61F2/1635 , A61F9/0017 , A61F9/007 , A61F2002/1699 , A61F2002/30581 , A61F2002/30583 , A61F2210/0085 , A61L27/18 , A61L27/50 , A61L2430/16 , C08L83/04
摘要： The invention relates to a multi-lens intraocular lens system having an accommodation material between the lenses. The system comprises an posterior lens attached to the posterior surface of the capsular bag and an anterior lens attached to the anterior surface of the capsular bag. The anterior and posterior lenses have different optical properties providing different degrees and types of correction. An accommodation material is place between the anterior and posterior lenses. The accommodation material may comprise of one or more macromers, which, when polymerized, adjust the properties of the accommodation material.
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公开(公告)号：US07988285B2
公开(公告)日：2011-08-02
申请号：US12628344
申请日：2009-12-01
CPC分类号： A61F2/1624 , A61F2/1618 , A61F2/1627 , A61F2/1635 , A61L27/18 , A61L2430/16 , G02B1/043 , G02C7/06 , G02C2202/14 , C08L83/04
摘要： The invention relates to novel intraocular lenses. The lenses are capable of post-operative adjustment of their optical properties, including conversion from single focal lenses to multifocal lenses.
摘要翻译： 本发明涉及新型眼内透镜。 透镜能够对其光学性能进行术后调整，包括从单焦点透镜转换为多焦点透镜。
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公开(公告)号：US07281795B2
公开(公告)日：2007-10-16
申请号：US11083794
申请日：2005-03-18
CPC分类号： A61F2/1624 , A61F2/1618 , A61F2/1627 , A61F2/1635 , A61L27/18 , A61L2430/16 , G02B1/043 , G02C7/06 , G02C2202/14 , C08L83/04
摘要： The invention relates to novel intraocular lenses. The lenses are capable of post-operative adjustment of their optical properties, including conversion from single focal lenses to multifocal lenses.
摘要翻译： 本发明涉及新型眼内透镜。 透镜能够对其光学性能进行术后调整，包括从单焦点透镜转换为多焦点透镜。
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9.发明授权Method for making novel compositions capable of post fabrication modification 有权制备能够进行后制造改性的新型组合物的方法公开(公告)号：US08361353B2
公开(公告)日：2013-01-29
申请号：US11486615
申请日：2006-07-14
申请人： Axel Brait , Shiao H. Chang , Patrick Case
发明人： Axel Brait , Shiao H. Chang , Patrick Case
CPC分类号： B05D5/06 , A61F2/1627 , G02B1/041 , C08L83/04 , C08L79/00 , C08L33/08 , C08L33/10 , C08L85/02
摘要： The invention relates to a novel method for preparing materials whose properties can be manipulated after fabrication. In this process, a base material is created in a manner that provides spaces or voids which can then be filled with a modifying composition. The method is particularly useful in the manufacture of light adjustable optical elements such as intraocular lenses.
摘要翻译： 本发明涉及一种制备材料的新方法，其制造后可以操作其性能。 在该方法中，以提供空间或空隙的方式产生基材，然后可以用改性组合物填充基材。 该方法在制造可调光学元件如眼内透镜中特别有用。
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10.发明申请Method for improved retinal safety using the light adjustable lens (LAL) 审中-公开使用光调透镜（LAL）改善视网膜安全的方法公开(公告)号：US20080027537A1
公开(公告)日：2008-01-31
申请号：US11493358
申请日：2006-07-26
IPC分类号： A61F2/16
CPC分类号： A61F2/1635 , A61F2/1618 , A61L27/50 , A61L2430/16 , G02C2202/14
摘要： Embodiments of the invention involve intraocular lenses that are light adjustable to change a focal length of the lens after it has been implanted into a person or animal. The lens includes a layer of UV absorbent material located on a rear side, which is the side facing a retina. The lens may comprise a UV reducing rim that surrounds a peripheral portion of the lens, and reduces or blocks UV light from striking the retina.
摘要翻译： 本发明的实施例涉及可调节眼睛的眼内透镜，以便在将晶状体植入人或动物之后改变透镜的焦距。 透镜包括位于后侧的UV吸收材料层，其是面向视网膜的一侧。 透镜可以包括围绕透镜的周边部分的紫外线减少边缘，并且减少或阻挡来自打击视网膜的紫外光。
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