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1.发明申请DISPENSING NOZZLE FOR AUTOMATIC ANALYZER, AND AUTOMATIC ANALYZER INCLUDING SAME 有权用于自动分析仪的分配喷嘴和包括其的自动分析仪公开(公告)号：US20120251393A1
公开(公告)日：2012-10-04
申请号：US13515017
申请日：2010-11-26
申请人： Shinichi Taniguchi , Akihiro Nojima
发明人： Shinichi Taniguchi , Akihiro Nojima
CPC分类号： G01N35/026 , B01J2219/00612 , B01L3/02 , B01L2300/0838 , B01L2300/163 , C23C2/00 , G01N35/00623 , G01N35/04 , G01N35/1002 , G01N35/1004 , G01N2035/00277 , G01N2035/102 , G01N2035/1025
摘要： An automatic analyzer for analyzing samples, such as urine and blood, is adapted so that analysis measured values are not affected by carry over by a repeatedly used dispensing nozzle. Coating the surface of the dispensing nozzle with a chemisorbed polyethylene glycol derivative forms a molecular layer that inhibits the adsorption of biopolymers, to reduce carry over by the dispensing nozzle.
摘要翻译： 用于分析样品（例如尿液和血液）的自动分析仪适于使得分析测量值不受重复使用的分配喷嘴的转移影响。 用化学吸附的聚乙二醇衍生物涂布分配喷嘴的表面形成抑制生物聚合物吸附的分子层，以减少分配喷嘴的携带。
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2.发明申请PIPETTING NOZZLE FOR AUTOANALYZER, METHOD FOR PRODUCING SAME AND AUTOANALYZER USING SAME 审中-公开用于自动加速器的管式喷嘴，用于生产它们的方法和使用它的自动分解器公开(公告)号：US20120020836A1
公开(公告)日：2012-01-26
申请号：US13147168
申请日：2010-01-05
CPC分类号： G01N35/1004 , B01L3/0275 , B01L2200/141 , B01L2300/0645 , B01L2300/161 , B01L2300/163
摘要： In an autoanalyzer for analyzing samples, such as urine and blood, analytical and measured values are prevented from being affected by carry-over caused by the repeated use of a pipetting nozzle. A molecular layer for inhibiting the adsorption of biological polymers is formed by coating surfaces of the pipetting nozzle with a polyethylene glycol derivative chemisorbed thereto, thereby reducing carry-over caused by the pipetting nozzle.
摘要翻译： 在用于分析样品（如尿液和血液）的自动分析仪中，可以防止分析和测量值受到重复使用移液喷嘴引起的滞留的影响。 通过用吸附喷嘴的聚乙二醇衍生物涂布移液喷嘴的表面，形成用于抑制生物聚合物吸附的分子层，从而减少由移液喷嘴引起的滞留。
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3.发明授权公开(公告)号：US08802008B2
公开(公告)日：2014-08-12
申请号：US13515017
申请日：2010-11-26
申请人： Shinichi Taniguchi , Akihiro Nojima
发明人： Shinichi Taniguchi , Akihiro Nojima
IPC分类号： G01N21/00 , B05D3/02 , B05D3/12 , G01N35/02 , C23C2/00 , G01N35/10 , G01N31/00 , B01L3/02 , G01N35/04
CPC分类号： G01N35/026 , B01J2219/00612 , B01L3/02 , B01L2300/0838 , B01L2300/163 , C23C2/00 , G01N35/00623 , G01N35/04 , G01N35/1002 , G01N35/1004 , G01N2035/00277 , G01N2035/102 , G01N2035/1025
摘要： An automatic analyzer for analyzing samples, such as urine and blood, is adapted so that analysis measured values are not affected by carry over by a repeatedly used dispensing nozzle. Coating the surface of the dispensing nozzle with a chemisorbed polyethylene glycol derivative forms a molecular layer that inhibits the adsorption of biopolymers, to reduce carry over by the dispensing nozzle.
摘要翻译： 用于分析样品（例如尿液和血液）的自动分析仪适于使得分析测量值不受重复使用的分配喷嘴的转移影响。 用化学吸附的聚乙二醇衍生物涂布分配喷嘴的表面形成抑制生物聚合物吸附的分子层，以减少分配喷嘴的携带。
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4.发明申请Dispensing Nozzle for Autoanalyzer, Autoanalyzer Equipped with the Nozzle, and Method for Producing Dispensing Nozzle for Autoanalyzer 审中-公开自动分析仪分配喷嘴，配有喷嘴的自动分析仪，自动分析仪生产点胶喷嘴的方法公开(公告)号：US20130171025A1
公开(公告)日：2013-07-04
申请号：US13699552
申请日：2011-07-11
IPC分类号： G01N35/10
CPC分类号： G01N35/1002 , G01N35/10 , G01N35/1004
摘要： In an autoanalyzer for analyzing a specimen such as urine and blood, protecting a measurement value of analysis from influence of a dispensing nozzle repeatedly used. For this purpose, a phosphonic acid derivative or a phosphoric acid derivative is chemically adsorbed on the surface of the dispensing nozzle. In this manner, a molecular layer for suppressing adsorption of biopolymers or adhesion of a specimen per se is formed on the nozzle surface to prevent accuracy of analysis from being influenced.
摘要翻译： 在用于分析诸如尿液和血液的样品的自动分析仪中，保护分析测量值不受重复使用的分注喷嘴的影响。 为此，膦酸衍生物或磷酸衍生物被化学吸附在分配喷嘴的表面上。 以这种方式，在喷嘴表面上形成用于抑制生物聚合物的吸附的分子层或试样本身的附着，以防止分析的精度受到影响。
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公开(公告)号：US08444936B2
公开(公告)日：2013-05-21
申请号：US13147152
申请日：2010-01-05
IPC分类号： B01L3/02
CPC分类号： G01N35/1004 , B01L3/021 , B01L2300/165
摘要： There is provided a highly reliable autoanalyzer less liable to sample and reagent carry-over and capable of preventing contamination and precisely pipetting samples and reagents. Using a sample pipetting nozzle 27 having water-repellent surfaces, a sample is pipetted from a sample cell 25 to a reaction cell 4 having a hydrophilic bottom face.
摘要翻译： 提供了一种高度可靠的自动分析仪，对样品和试剂携带不太敏感，并能够防止污染和精确移液样品和试剂。 使用具有防水表面的样品移液喷嘴27，将样品从样品池25吸移到具有亲水底面的反应池4。
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公开(公告)号：US20110300035A1
公开(公告)日：2011-12-08
申请号：US13147152
申请日：2010-01-05
IPC分类号： B01L3/02
CPC分类号： G01N35/1004 , B01L3/021 , B01L2300/165
摘要： There is provided a highly reliable autoanalyzer less liable to sample and reagent carry-over and capable of preventing contamination and precisely pipetting samples and reagents. Using a sample pipetting nozzle 27 having water-repellent surfaces, a sample is pipetted from a sample cell 25 to a reaction cell 4 having a hydrophilic bottom face.
摘要翻译： 提供了一种高度可靠的自动分析仪，对样品和试剂携带不太敏感，并能够防止污染和精确移液样品和试剂。 使用具有防水表面的样品移液喷嘴27，将样品从样品池25吸移到具有亲水底面的反应池4。
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公开(公告)号：US20230416301A1
公开(公告)日：2023-12-28
申请号：US18299955
申请日：2023-04-13
IPC分类号： C07K1/12
CPC分类号： C07K1/12
摘要： Provided is a pretreatment method for structural analysis of a protein, including chemical modifying and fragmenting a protein to be analyzed, in which in the fragmenting, the protein is treated at a temperature of 60 to 99° C. in the presence of a heat-resistant protease that has four or more cleavage sites and is soluble or immobilized on a carrier.
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