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    Method of testing inert, displaceable diluents used in forming shaped hydrogel articles
    10.
    发明授权
    Method of testing inert, displaceable diluents used in forming shaped hydrogel articles 失效
    用于形成成形水凝胶制品的惰性可置换稀释剂的测试方法

    公开(公告)号：US5736409A

    公开(公告)日：1998-04-07

    申请号：US645999

    申请日：1996-05-14

    申请人： Ivan M. Nunez ,  Frank F. Molock ,  Laura D. Elliott ,  James D. Ford

    发明人： Ivan M. Nunez ,  Frank F. Molock ,  Laura D. Elliott ,  James D. Ford

    IPC分类号： C08J5/00 ,  B29D11/02 ,  C08F2/00 ,  C08F2/44 ,  C08F2/48 ,  C08L71/02 ,  G02B1/04 ,  G01N25/20 ,  B29D11/00

    CPC分类号： G02B1/043 ,  C08F2/00 ,  Y10S524/916

    摘要： Method of testing inert displaceable diluents used in forming shaped hydrogel articles such as soft contact lenses prepared by the steps of: (1) molding or casting a polymerization mixture including: (a) a monomer mixture having a major proportion of one or more hydrophilic monomers such as 2-hydroxyethyl methacrylate, and one or more cross-linking monomers; and (b) an inert, displaceable diluent chosen from: (i) ethoxylated alkyl glucoside; (ii) ethoxylated bisphenol A; (iii) polyethylene glycol; (iv) mixture of propoxylated and ethoxylated alkyl glucoside; (v) single phase mixture of ethoxylated or propoxylated alkyl gtucoside and C.sub.2-12 dihydric alcohol; (vi) adduct of .epsilon.-caprolactone and C.sub.2-6 alkanediols and triols;(vii) ethoxylated C.sub.3-6 alkanetriol; and (viii) mixtures of one or more of (i) through (vii), under conditions to polymerize the monomer mixture to produce a shaped gel of a copolymer of the monomers and the diluent; and (2) thereafter replacing the diluent with water.

    摘要翻译： 测试用于形成成形水凝胶制品（例如由以下步骤制备的软性隐形眼镜）的惰性可置换稀释剂的方法：（1）模制或浇铸聚合混合物，其包括：（a）主要比例的一种或多种亲水单体的单体混合物 如甲基丙烯酸2-羟乙酯和一种或多种交联单体; 和（b）惰性的可置换的稀释剂，其选自：（i）乙氧基化烷基葡糖苷; （ii）乙氧基化双酚A; （iii）聚乙二醇; （iv）丙氧基化和乙氧基化烷基葡糖苷的混合物; （v）乙氧基化或丙氧基化烷基葡糖苷和C2-12二元醇的单相混合物; （vi）ε-己内酯和C 2-6烷二醇和三醇的加合物; （vii）乙氧基化C3-6烷醇三醇; 和（viii）（i）至（vii）中的一种或多种的混合物，在使单体混合物聚合以产生单体和稀释剂的共聚物的成形凝胶的条件下; 和（2）此后用水代替稀释剂。