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8 条记录 (耗时 0.037 秒)

    BGS 4
    1.
    发明授权
    BGS 4 失效

    公开(公告)号：US07456256B2

    公开(公告)日：2008-11-25

    申请号：US11726220

    申请日：2007-03-21

    申请人： Shujian Wu ,  Stanley R. Krystek, Jr. ,  Liana M. Lee ,  John N. Feder ,  Janet D. Cheng

    发明人： Shujian Wu ,  Stanley R. Krystek, Jr. ,  Liana M. Lee ,  John N. Feder ,  Janet D. Cheng

    IPC分类号： C07K14/47 ,  C12N15/07 ,  C12N15/64 ,  C12P21/02

    CPC分类号： C07K14/705 ,  A61K38/00

    摘要： The present invention provides novel polynucleotides encoding BGS-2, 3, and 4 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing the polypeptides of the present invention. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-2, 3, and 4 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

    摘要翻译： 本发明提供了编码BGS-2,3和4多肽的新型多核苷酸，其片段及其同源物。 还提供载体，宿主细胞，抗体，以及用于产生本发明多肽的重组和合成方法。 本发明还涉及将这些新型BGS-2,3和4多肽应用于诊断，治疗和/或预防与这些多肽相关的各种疾病和/或病症的诊断和治疗方法。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。

    Antibodies that bind to BGS-4
    2.
    发明授权
    Antibodies that bind to BGS-4 失效
    与BGS-4结合的抗体

    公开(公告)号：US07705134B2

    公开(公告)日：2010-04-27

    申请号：US12283245

    申请日：2008-09-10

    申请人： Shujian Wu ,  Stanley R. Krystek, Jr. ,  Liana M. Lee ,  John N. Feder ,  Janet D. Cheng

    发明人： Shujian Wu ,  Stanley R. Krystek, Jr. ,  Liana M. Lee ,  John N. Feder ,  Janet D. Cheng

    IPC分类号： C07K16/18 ,  C07K14/47 ,  C12P21/02 ,  C12N15/63

    CPC分类号： C07K14/705 ,  A61K38/00

    摘要： The present invention provides novel polynucleotides encoding BGS-4 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing the polypeptides of the present invention. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-4 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

    摘要翻译： 本发明提供了编码BGS-4多肽的新型多核苷酸，其片段和同源物。 还提供载体，宿主细胞，抗体，以及用于产生本发明多肽的重组和合成方法。 本发明还涉及将这些新型BGS-4多肽应用于诊断，治疗和/或预防与这些多肽相关的各种疾病和/或病症的诊断和治疗方法。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。

    Polynucleotides encoding three novel human cell surface proteins with leucine rich repeats and immunologobulin folds, BGS2, 3, and 4 and variants thereof
    3.
    发明授权
    Polynucleotides encoding three novel human cell surface proteins with leucine rich repeats and immunologobulin folds, BGS2, 3, and 4 and variants thereof 失效
    编码具有富含亮氨酸重复序列和免疫球蛋白折叠的三种新型人细胞表面蛋白的多核苷酸，BGS2,3和4及其变体

    公开(公告)号：US07223558B2

    公开(公告)日：2007-05-29

    申请号：US10193477

    申请日：2002-07-11

    申请人： Shujian Wu ,  Stanley R. Krystek ,  Liana Lee ,  John N. Feder ,  Janet D. Cheng

    发明人： Shujian Wu ,  Stanley R. Krystek ,  Liana Lee ,  John N. Feder ,  Janet D. Cheng

    IPC分类号： C12N15/12 ,  C12N5/10 ,  C12P21/02 ,  C07K14/47

    CPC分类号： C07K14/705 ,  A61K38/00

    摘要： The present invention provides novel polynucleotides encoding BGS-2, 3, and 4 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-2, 3, and 4 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

    摘要翻译： 本发明提供了编码BGS-2,3和4多肽的新型多核苷酸，其片段及其同源物。 还提供了载体，宿主细胞，抗体以及用于产生所述多肽的重组和合成方法。 本发明还涉及将这些新型BGS-2,3和4多肽应用于诊断，治疗和/或预防与这些多肽相关的各种疾病和/或病症的诊断和治疗方法。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。

    Antibodies that bind to BGS-4
    4.
    发明申请
    Antibodies that bind to BGS-4 失效
    与BGS-4结合的抗体

    公开(公告)号：US20090088385A1

    公开(公告)日：2009-04-02

    申请号：US12283245

    申请日：2008-09-10

    申请人： Shujian Wu ,  Stanley R. Krystek ,  Liana Lee ,  John N. Feder ,  Janet D. Cheng

    发明人： Shujian Wu ,  Stanley R. Krystek ,  Liana Lee ,  John N. Feder ,  Janet D. Cheng

    IPC分类号： A61K38/16 ,  C07K16/00 ,  G01N33/68 ,  A61P37/00 ,  A61P29/00 ,  A61P35/00 ,  A61P9/00

    CPC分类号： C07K14/705 ,  A61K38/00

    摘要： The present invention provides novel polynucleotides encoding BGS-4 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing the polypeptides of the present invention. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-4 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

    摘要翻译： 本发明提供了编码BGS-4多肽的新型多核苷酸，其片段和同源物。 还提供载体，宿主细胞，抗体，以及用于产生本发明多肽的重组和合成方法。 本发明还涉及将这些新型BGS-4多肽应用于诊断，治疗和/或预防与这些多肽相关的各种疾病和/或病症的诊断和治疗方法。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。