公开(公告)号：US09395777B2

公开(公告)日：2016-07-19

申请号：US14017389

申请日：2013-09-04

申请人： Soo Yong Kim ,  Ju Hwan Kim ,  Jun Ho Huh ,  Kee Moon Chun

发明人： Soo Yong Kim ,  Ju Hwan Kim ,  Jun Ho Huh ,  Kee Moon Chun

IPC分类号： G06F1/32 ,  G06F1/26

CPC分类号： G06F1/26 ,  G06F1/3228 ,  G06F1/3243 ,  G06F1/3287 ,  G06F1/3296 ,  Y02D10/152 ,  Y02D10/171 ,  Y02D50/20

摘要： A system-on-chip (SoC) which includes a plurality of intellectual properties (IP cores) which communicate data with a memory device operates by monitoring whether a data transaction occurs between at least one of the IP cores and the memory device, determining an operation state of the IP core according to the result of the monitoring, and supplying the IP core with power corresponding to the operation state of the IP core.

摘要翻译： 包括与存储器件通信数据的多个知识产权（IP核）的片上系统（SoC）通过监视数据交易是否在至少一个IP核与存储器件之间发生，确定一个 根据监控结果，IP核的运行状态，并向IP核提供与IP核的运行状态相对应的功率。

公开(公告)号：US20140242606A1

公开(公告)日：2014-08-28

申请号：US14128535

申请日：2012-06-25

申请人： Sang Jeon Chung ,  Ju Hwan Kim ,  Elena Ruchkina ,  Hyo Jin Kang

发明人： Sang Jeon Chung ,  Ju Hwan Kim ,  Elena Ruchkina ,  Hyo Jin Kang

IPC分类号： G01N33/58 ,  G01N33/573

CPC分类号： G01N33/582 ,  G01N21/6428 ,  G01N33/542 ,  G01N33/573 ,  G01N2021/6441 ,  G01N2458/00

摘要： The present invention relates to a probe for iFRET and use thereof. Specifically, the present invention relates to a novel probe for iFRET, a method for preparing the probe for iFRET, a method for searching a target protein-specific binding site or a molecule having the binding site using the probe for iFRET, and a method for imaging the target protein using the probe for iFRET. The probe for iFRET according to the present invention utilizes an amino acid in a protein as a fluorescent donor, unlike the conventional FRET method. Therefore, only one fluorescent material is used, and its emission wavelength is distinct from the intrinsic fluorescence of the protein. Thus, high specificity and sensitivity are ensured, and the quantity, activity and mechanism of various proteins can be analyzed in an easy and accurate manner.

摘要翻译： 本发明涉及一种用于iFRET的探针及其用途。 具体地说，本发明涉及用于iFRET的新型探针，用于制备iFRET探针的方法，使用所述iFRET探针来搜索靶蛋白特异性结合位点的方法或具有结合位点的分子，以及用于 使用iFRET的探针成像靶蛋白。 根据本发明的iFRET的探针利用蛋白质中的氨基酸作为荧光供体，与常规的FRET方法不同。 因此，仅使用一种荧光材料，其发射波长与蛋白质的固有荧光不同。 因此，确保了高度的特异性和灵敏度，可以容易且准确地分析各种蛋白质的数量，活性和机理。

公开(公告)号：US20140170769A1

公开(公告)日：2014-06-19

申请号：US14128560

申请日：2012-04-23

申请人： Sang Jeon Chung ,  Hyo Jin Kang ,  Ju Hwan Kim

发明人： Sang Jeon Chung ,  Hyo Jin Kang ,  Ju Hwan Kim

IPC分类号： G01N21/64

CPC分类号： G01N21/6428 ,  G01N21/6458 ,  G01N33/542 ,  G01N33/6803 ,  G01N2021/6441

摘要： A microscope apparatus for detecting or imaging a target protein using a probe for intrinsic fluorescence resonance energy transfer (iFRET) according to the present invention comprises: a light irradiation unit that irradiates a first light having a wavelength range for exciting an amino acid in the target protein and a second light having a wavelength range for exciting a fluorescent molecule of the probe for iFRET; an objective lens that allows the lights irradiated from the light irradiation unit to be incident onto a sample into which the probe for iFRET is introduced; and a recognition unit that detects a first light emitting signal generated from the probe for iFRET by irradiating the first light having a wavelength range for exciting an amino acid in the target protein onto the sample and a second light emitting signal generated from the probe for iFRET by irradiating the second light having a wavelength range for exciting a fluorescent molecule of the probe for iFRET onto the sample, wherein the probe for iFRET includes: a binding site specific to a target protein or a molecule which has the binding site; and a fluorescent molecule having an acceptor function with respect to intrinsic fluorescence of the target protein, which are bonded to each other directly or by a linker.

摘要翻译： 根据本发明的用于使用本征荧光共振能量转移（iFRET）的探针检测或成像目标蛋白质的显微镜装置包括：照射具有用于激发靶中的氨基酸的波长范围的第一光的光照射单元 蛋白质和具有用于激发用于iFRET的探针的荧光分子的波长范围的第二光; 允许从光照射单元照射的光入射到其中引入用于iFRET的探针的样品的物镜; 以及识别单元，通过将具有用于激发目标蛋白质中的氨基酸的波长范围的第一光照射到样品上，并且从用于iFRET的探针产生的第二发光信号，检测从探针产生的用于iFRET的第一发光信号 通过将具有用于激发iFRET探针的荧光分子的波长范围的第二光照射在样品上，其中所述iFRET探针包括：对靶蛋白或具有结合位点的分子特异性的结合位点; 以及相对于靶蛋白的固有荧光具有受体功能的荧光分子，它们直接或通过连接体彼此结合。

公开(公告)号：US07191988B2

公开(公告)日：2007-03-20

申请号：US11110708

申请日：2005-04-21

申请人： Mun Sub Kim ,  Jai Kwon Lee ,  Jin Yong Mo ,  Deug Yong Park ,  Hyung Suk Han ,  Ju Hwan Kim

发明人： Mun Sub Kim ,  Jai Kwon Lee ,  Jin Yong Mo ,  Deug Yong Park ,  Hyung Suk Han ,  Ju Hwan Kim

IPC分类号： F16L3/22

CPC分类号： F16L3/085 ,  Y10S248/913

摘要： A pipe fixing device comprising a plurality of pipes, for conducting liquid or gas, arranged to cross each other, and a fixing member for fixing the plurality of pipes. The fixing member comprises a plurality of pipe fixing bores, and a plurality of fitting bores for the fitting of bands used to tighten the pipes. The present invention can secure not only easy insertion of the pipes arranged to cross each other, but also enhancement in a coupling force of the pipes through the use of the tightening bands, resulting in stable and reliable fixation of the pipes.

摘要翻译： 一种管道固定装置，包括多个用于传导液体或气体的管道，被布置为彼此交叉，以及用于固定多个管道的固定构件。 固定构件包括多个管固定孔，以及用于装配用于紧固管的带的多个配合孔。 本发明不仅可以确保布置成彼此交叉的管道的容易插入，而且可以确保通过使用紧固带增强管道的联接力，从而稳定可靠地固定管道。

公开(公告)号：US5890417A

公开(公告)日：1999-04-06

申请号：US687936

申请日：1996-07-29

申请人： Ju Hwan Kim

发明人： Ju Hwan Kim

IPC分类号： F04B3/00 ,  F04B39/00 ,  F04B49/12 ,  F04B53/14 ,  F16J1/14

CPC分类号： F04B39/0005 ,  F04B49/121

摘要： A piston/cylinder assembly for a reciprocating compressor has a piston comprising telescopingly connected first and second piston members. The first piston member is connected to a connecting rod. The second piston member is provided with a piston head and is connected to the first piston member in such a way as to be movable axially relative to the first piston member by a predetermined distance. A spring is interposed between the first piston member and the second piston member to yieldably urge the first and second piston members axially apart.

摘要翻译： 用于往复式压缩机的活塞/气缸组件具有包括可伸缩连接的第一和第二活塞构件的活塞。 第一活塞构件连接到连接杆。 第二活塞构件设置有活塞头，并且以相对于第一活塞构件轴向移动预定距离的方式连接到第一活塞构件。 弹簧设置在第一活塞构件和第二活塞构件之间，以可收缩地推动第一和第二活塞构件轴向分开。