摘要:
The invention discloses the use of a new cell growth related peptide. More precisely, the invention serves as a marker for cell proliferation. The marker is a peptide which is an exposed part of a cellular enzyme. This peptide is as well particularly useful as an aid in production of highly selective reactive molecules. The peptide is a part of thymidine kinase TK1 and has the sequence of SEQ ID NO: 1 or SEQ ID NO: 2.
摘要:
The present invention involves early prediction of progression of a cancer disease in patients treated for cancer. According to the invention the binding response level of an immunoreactive material (IM) comprising thymidine kinase 1 (TK1) protein is determined in a body fluid sample of a patient and the likelihood of progress of the cancer disease is estimated based directly on this determined IM binding response level. Those patients that run a risk of cancer progress and tumor relapse 1-15 years after the cancer treatment may be identified directly by the IM binding response level according to the invention within a few months following initiation of the treatment.
摘要:
A technique includes generating one or more sweep sequences for one or more seismic vibrators for a seismic survey and evaluating a cost for the sequence(s). The technique includes perturbing the sequence(s) and continuing the evaluation and perturbing until the cost is within a limit or a maximum number of perturbations is reached.
摘要:
Novel thymidine kinase (TK1) derived peptide consisting of the amino acid sequence of SEQ ID NO:1 or SEQ ID NO:2 is employed to obtain ligands having specificity to the peptide. The ligand may be an antibody or fragment thereof and may be used in various methods and kits for health screening and the like.
摘要翻译:使用由SEQ ID NO:1或SEQ ID NO:2的氨基酸序列组成的新型胸苷激酶(TK1)衍生肽获得对肽具有特异性的配体。 配体可以是抗体或其片段,并且可以用于各种用于健康检查等的方法和试剂盒。
摘要:
A technique includes generating one or more sweep sequences for one or more seismic vibrators for a seismic survey and evaluating a cost for the sequence(s). The technique includes perturbing the sequence(s) and continuing the evaluation and perturbing until the cost is within a limit or a maximum number of perturbations is reached.
摘要:
Novel thymidine kinase (TK1) derived peptide consisting of the amino acid sequence of SEQ ID NO:1 or SEQ ID NO:2 is employed to obtain ligands having specificity to the peptide. The ligand may be an antibody or fragment thereof and may be used in various methods and kits for health screening and the like.
摘要翻译:使用由SEQ ID NO:1或SEQ ID NO:2的氨基酸序列组成的新型胸苷激酶(TK1)衍生肽获得对肽具有特异性的配体。 配体可以是抗体或其片段,并且可以用于各种用于健康检查等的方法和试剂盒。
摘要:
The present invention concerns a new method that enables safe, rapid, accurate and specific determination of thymidine kinase 1 activity in human or animal body fluids and tissue/cell extracts for routine analysis of samples with low levels of activity by using AZT or 3′ derivatives of thymidine as substrate and determining the phosphorylated products formed in the reaction with thymidine kinase 1 activity. The invention further relates to the use of said method for the diagnosis, monitoring and prognostics of diseases such as cancer.
摘要:
In an absorption refrigerating apparatus (18) the pump pipe (42) is made of a material, which is more corrosion resistant to the working medium than the material of the rest of the apparatus. In order to prevent galvanic corrosion in the boiler the pump pipe (42) can be electrically insulated (72, 74) from the rest of the boiler.