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公开(公告)号：US09096883B2
公开(公告)日：2015-08-04
申请号：US12808317
申请日：2008-12-18
CPC分类号： C12Q1/10 , C12M25/06 , C12M41/36 , C12Q1/04 , C12Q1/06 , C12Q1/24 , G01N2333/245 , Y02A50/54
摘要： Methods and systems for detecting the presence of a target microorganism in a liquid sample are provided. Methods comprise the steps of passing the liquid sample through a surface filter, placing the surface filter into contact with a culture device, incubating the culture device for a period of time and detecting the presence of a target microorganism. Methods may be used with an automated detection system.
摘要翻译： 提供了用于检测液体样品中目标微生物的存在的方法和系统。 方法包括使液体样品通过表面过滤器，使表面过滤器与培养装置接触，培养培养装置一段时间并检测目标微生物的存在的步骤。 方法可以与自动检测系统一起使用。
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公开(公告)号：US20110143334A1
公开(公告)日：2011-06-16
申请号：US12808317
申请日：2008-12-18
CPC分类号： C12Q1/10 , C12M25/06 , C12M41/36 , C12Q1/04 , C12Q1/06 , C12Q1/24 , G01N2333/245 , Y02A50/54
摘要： Methods and systems for detecting the presence of a target microorganism in a liquid sample are provided. Methods comprise the steps of passing the liquid sample through a surface filter, placing the surface filter into contact with a culture device, incubating the culture device for a period of time and detecting the presence of a target microorganism. Methods may be used with an automated detection system.
摘要翻译： 提供了用于检测液体样品中目标微生物的存在的方法和系统。 方法包括使液体样品通过表面过滤器，使表面过滤器与培养装置接触，培养培养装置一段时间并检测目标微生物的存在的步骤。 方法可以与自动检测系统一起使用。
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公开(公告)号：US08828653B2
公开(公告)日：2014-09-09
申请号：US12743528
申请日：2008-11-20
申请人： Cynthia D. Zook , Robert H. Silbernagel , Barbara L. Horter , Henry J. Lubrant , Robert E. Koeritzer
发明人： Cynthia D. Zook , Robert H. Silbernagel , Barbara L. Horter , Henry J. Lubrant , Robert E. Koeritzer
IPC分类号： C12Q1/04 , C12Q1/24 , C12Q1/00 , C12N1/20 , C12N1/00 , G01N1/02 , C12N1/08 , C12N1/18 , C12N1/24 , C12M1/34
摘要： The present invention refers to articles for collecting samples from a surface, articles for microbiological analyses of said samples, and methods of use of said articles. The articles include sample collectors, sample housings with optional barrier layers, and sample-ready reagent strips comprising hydrophilic agents to grow and detect microorganisms. The disclosure includes methods to collect, detect, and quantify microorganisms in a surface sample.
摘要翻译： 本发明涉及用于从表面收集样品的物品，用于所述样品的微生物分析的物品和所述物品的使用方法。 这些物品包括样品收集器，具有可选阻挡层的样品壳体和包含亲水试剂的样品准备试剂条，以生长和检测微生物。 本公开包括收集，检测和定量表面样品中的微生物的方法。
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公开(公告)号：US08647574B2
公开(公告)日：2014-02-11
申请号：US12743252
申请日：2008-11-19
申请人： Kurt J. Halverson , Stephen C. P. Joseph , Raj Rajagopal , David J. Velasquez , Cynthia D. Zook , Sailaja Chandrapati , Daniel E. Siltberg , Paul J. Cobian , Theresa J. Gerten
发明人： Kurt J. Halverson , Stephen C. P. Joseph , Raj Rajagopal , David J. Velasquez , Cynthia D. Zook , Sailaja Chandrapati , Daniel E. Siltberg , Paul J. Cobian , Theresa J. Gerten
IPC分类号： G01N15/06
CPC分类号： G01N1/38 , G01N1/4077 , G01N2001/4088
摘要： A system and method for preparing and collecting samples for analyte testing. The system can include a sample preparation system and a sample collection system coupled to the sample preparation system. The sample preparation system can include at least one of a deformable self-supporting receptacle comprising a reservoir and a freestanding receptacle comprising a reservoir. The reservoir can be adapted to contain a liquid composition. The sample collection system can be positioned in fluid communication with a reservoir of the sample preparation system, and can be adapted to capture an analyte of interest. The method can include providing a fluid path defined at least partially by the sample preparation system and the sample collection system, positioning the liquid composition in a reservoir of the sample preparation system, and moving at least a portion of the liquid composition in the fluid path to the sample collection system.
摘要翻译： 用于制备和收集样品用于分析物测试的系统和方法。 该系统可以包括与样品制备系统耦合的样品制备系统和样品收集系统。 样品制备系统可以包括可变形的自支撑容器中的至少一个，其包括储存器和包括储存器的独立容器。 储存器可以适于容纳液体组合物。 样品收集系统可以定位成与样品制备系统的储存器流体连通，并且可以适于捕获感兴趣的分析物。 该方法可以包括提供至少部分地由样品制备系统和样品收集系统限定的流体路径，将液体组合物定位在样品制备系统的储存器中，并且将至少一部分液体组合物移动到流体路径 到采样系统。
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公开(公告)号：US20130149738A1
公开(公告)日：2013-06-13
申请号：US13807058
申请日：2011-06-27
IPC分类号： C12Q1/04
摘要： The disclosure provides culture devices and methods for a microorganism in a sample. The devices include a base member, a cover sheet, an adhesive layer coupled to the base member or the cover sheet, and a cold water-soluble gelling agent disposed on the base member; wherein the devices are substantially optically transmissive when the gelling agent is hydrated with a clear liquid. Methods of use include detecting or enumerating microorganisms. The methods further provide for detecting a microorganism by detecting the presence or size of an abiogenic gas bubble (540, 542) in a culture device.
摘要翻译： 本公开提供了样品中微生物的培养装置和方法。 这些装置包括基底部件，覆盖片，连接到基底部件或覆盖片的粘合剂层，以及设置在基底部件上的冷水溶性胶凝剂; 其中当胶凝剂与透明液体水合时，所述装置基本上是光学透射的。 使用方法包括检测或列举微生物。 所述方法进一步提供通过检测培养装置中的生物气体气泡（540,542）的存在或大小来检测微生物。
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公开(公告)号：US09127300B2
公开(公告)日：2015-09-08
申请号：US13807058
申请日：2011-06-27
摘要： The disclosure provides culture devices and methods for a microorganism in a sample. The devices include a base member, a cover sheet, an adhesive layer coupled to the base member or the cover sheet, and a cold water-soluble gelling agent disposed on the base member; wherein the devices are substantially optically transmissive when the gelling agent is hydrated with a clear liquid. Methods of use include detecting or enumerating microorganisms. The methods further provide for detecting a microorganism by detecting the presence or size of an abiogenic gas bubble in a culture device.
摘要翻译： 本公开提供了样品中微生物的培养装置和方法。 这些装置包括基底部件，覆盖片，连接到基底部件或覆盖片的粘合剂层，以及设置在基底部件上的冷水溶性胶凝剂; 其中当胶凝剂与透明液体水合时，所述装置基本上是光学透射的。 使用方法包括检测或列举微生物。 该方法进一步提供了通过检测培养装置中的生物气泡的存在或大小来检测微生物。
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公开(公告)号：US20100248215A1
公开(公告)日：2010-09-30
申请号：US12743449
申请日：2008-11-19
申请人： Kurt J. Halverson , Stephen C.P. Joseph , Raj Rajagopal , Matthew D. Reier , David J. Velasquez , Cynthia D. Zook , Sailaja Chandrapati
发明人： Kurt J. Halverson , Stephen C.P. Joseph , Raj Rajagopal , Matthew D. Reier , David J. Velasquez , Cynthia D. Zook , Sailaja Chandrapati
CPC分类号： G01N1/38
摘要： A system and method for preparing and delivering samples for analyte testing. The system can include a sample preparation system and a sample delivery system coupled to the sample preparation system. The sample preparation system can include a deformable self-supporting receptacle comprising a reservoir adapted to contain a liquid composition comprising a source and a diluent. The sample delivery system can include a valve positioned in fluid communication with the reservoir and adapted to control the removal of a sample from the sample preparation system. The method can include applying pressure to the deformable self-supporting receptacle to remove a sample from the sample preparation system via the sample delivery system.
摘要翻译： 用于制备和递送样品以进行分析物测试的系统和方法。 该系统可以包括与样品制备系统耦合的样品制备系统和样品递送系统。 样品制备系统可以包括可变形的自支撑容器，其包括适于容纳包含源和稀释剂的液体组合物的储存器。 样品输送系统可以包括定位成与储存器流体连通的阀，并适于控制样品从样品制备系统中的去除。 该方法可以包括向可变形的自支撑容器施加压力，以经由样品输送系统从样品制备系统移除样品。
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公开(公告)号：US08569072B2
公开(公告)日：2013-10-29
申请号：US12743449
申请日：2008-11-19
申请人： Kurt J. Halverson , Stephen C. P. Joseph , Raj Rajagopal , Matthew D. Reier , David J. Velasquez , Cynthia D. Zook , Sailaja Chandrapati
发明人： Kurt J. Halverson , Stephen C. P. Joseph , Raj Rajagopal , Matthew D. Reier , David J. Velasquez , Cynthia D. Zook , Sailaja Chandrapati
IPC分类号： G01N1/00
CPC分类号： G01N1/38
摘要： A system and method for preparing and delivering samples for analyte testing. The system can include a sample preparation system and a sample delivery system coupled to the sample preparation system. The sample preparation system can include a deformable self-supporting receptacle comprising a reservoir adapted to contain a liquid composition comprising a source and a diluent. The sample delivery system can include a valve positioned in fluid communication with the reservoir and adapted to control the removal of a sample from the sample preparation system. The method can include applying pressure to the deformable self-supporting receptacle to remove a sample from the sample preparation system via the sample delivery system.
摘要翻译： 用于制备和递送样品以进行分析物测试的系统和方法。 该系统可以包括与样品制备系统耦合的样品制备系统和样品递送系统。 样品制备系统可以包括可变形的自支撑容器，其包括适于容纳包含源和稀释剂的液体组合物的储存器。 样品输送系统可以包括定位成与储存器流体连通的阀，并适于控制样品从样品制备系统中的去除。 该方法可以包括向可变形的自支撑容器施加压力，以经由样品输送系统从样品制备系统移除样品。
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公开(公告)号：US20120028297A1
公开(公告)日：2012-02-02
申请号：US12743528
申请日：2008-11-20
申请人： Cynthia D. Zook , Robert H. Silbernagel , Barbara L. Horter , Henry J. Lubrant , Robert E. Koeritzer
发明人： Cynthia D. Zook , Robert H. Silbernagel , Barbara L. Horter , Henry J. Lubrant , Robert E. Koeritzer
摘要： The present invention refers to articles for collecting samples from a surface, articles for microbiological analyses of said samples, and methods of use of said articles. The articles include sample collectors, sample housings with optional barrier layers, and sample-ready reagent strips comprising hydrophilic agents to grow and detect microorganisms. The disclosure includes methods to collect, detect, and quantify microorganisms in a surface sample.
摘要翻译： 本发明涉及用于从表面收集样品的物品，用于所述样品的微生物分析的物品和所述物品的使用方法。 这些物品包括样品收集器，具有可选阻挡层的样品壳体和包含亲水试剂的样品准备试剂条，以生长和检测微生物。 本公开包括收集，检测和定量表面样品中的微生物的方法。
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公开(公告)号：US20100248216A1
公开(公告)日：2010-09-30
申请号：US12743459
申请日：2008-11-19
申请人： Kurt J. Halverson , Stephen C.P. Joseph , Raj Rajagopal , Matthew D. Reier , David J. Velasquez , Cynthia D. Zook , Sailaja Chandrapati
发明人： Kurt J. Halverson , Stephen C.P. Joseph , Raj Rajagopal , Matthew D. Reier , David J. Velasquez , Cynthia D. Zook , Sailaja Chandrapati
CPC分类号： G01N1/38 , B01L3/505 , Y10T436/25
摘要： A system and method for preparing and analyzing samples. The system can include a sample preparation system and a sample detection system coupled to the sample preparation system. The sample preparation system can include a deformable self-supporting receptacle comprising a reservoir adapted to contain a liquid composition comprising a source and a diluent. The sample detection system can be positioned in fluid communication with the reservoir, and can be adapted to analyze a sample of the liquid composition for an analyte of interest. The system can further include a fluid path defined at least partially by the reservoir and the sample detection system. The method can include applying pressure to the deformable self-supporting receptacle to move a sample of the liquid composition in the fluid path to the sample detection system, and analyzing the sample for the analyte of interest with the sample detection system.
摘要翻译： 一种用于准备和分析样品的系统和方法。 该系统可以包括样品制备系统和与样品制备系统耦合的样品检测系统。 样品制备系统可以包括可变形的自支撑容器，其包括适于容纳包含源和稀释剂的液体组合物的储存器。 样品检测系统可以定位成与储存器流体连通，并且可以适于分析用于感兴趣的分析物的液体组合物的样品。 该系统还可以包括至少部分地由储存器和样本检测系统限定的流体路径。 该方法可以包括向可变形的自支撑容器施加压力以将流体路径中的液体组合物的样品移动到样品检测系统，并且用样品检测系统分析样品的感兴趣的分析物。
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