公开(公告)号：US20060282150A1

公开(公告)日：2006-12-14

申请号：US11148713

申请日：2005-06-08

申请人： Stephen Olson ,  Michael McGarry

发明人： Stephen Olson ,  Michael McGarry

IPC分类号： A61F2/06

CPC分类号： A61F2/966 ,  A61F2002/826 ,  A61F2002/9517 ,  A61M25/0136

摘要： Devices and methods are provided for operating and controlling an interventional element on an interventional catheter. The interventional element may be a stent or series of stents, a balloon, or any other interventional element for which length control is necessary or desirable. A handle member includes an elongated body and an actuator knob that rotates around the longitudinal axis of the body. Rotational movement of the actuator knob is translated to rotational movement of one or more lead screws by a system of gears, rollers, or combinations of gears and rollers. Each of one or more axially moveable members is positioned on a lead screw and attached to a portion of the catheter shaft in order to provide the ability to advance or retract the portion of the cathether shaft.

摘要翻译： 提供了用于在介入导管上操作和控制介入元件的装置和方法。 介入元件可以是支架或一系列支架，球囊或其长度控制是必要或期望的任何其它介入元件。 手柄构件包括细长主体和围绕主体的纵向轴线旋转的致动器旋钮。 致动器旋钮的旋转运动由一系列齿轮，滚子或齿轮和滚子的组合转换成一个或多个导螺杆的旋转运动。 一个或多个可轴向移动的构件中的每一个定位在导螺杆上并且附接到导管轴的一部分，以便提供推进或缩回导管轴部分的能力。

公开(公告)号：US20060055720A1

公开(公告)日：2006-03-16

申请号：US10938010

申请日：2004-09-10

申请人： Stephen Olson ,  Colin Maher

发明人： Stephen Olson ,  Colin Maher

IPC分类号： B41J29/393

CPC分类号： B41J2/2128 ,  B41J2/04508 ,  B41J2/04528 ,  B41J2/0458 ,  B41J2/04596 ,  B41J29/393

摘要： A method of intra-swath banding compensation in an imaging apparatus utilizing an ink jet printhead that reciprocates in a main scan direction, the ink jet printhead having a nozzle array with a plurality of nozzles, includes printing with the plurality of nozzles in the main scan direction a pattern of dots representative of the nozzle array; determining a variation in reflectance of the pattern of dots in a direction substantially perpendicular to the main scan direction; and storing in a memory associated with the printhead compensation values associated with each nozzle of the plurality of nozzles that is to be adjusted to correct for the variation in reflectance.

摘要翻译： 一种利用在主扫描方向上往复运动的喷墨打印头的成像设备中的带内条带补偿方法，具有多个喷嘴的喷嘴阵列的喷墨打印头包括在主扫描中用多个喷嘴进行打印 方向表示喷嘴阵列的点的图案; 确定在基本上垂直于主扫描方向的方向上的点图案的反射率的变化; 并存储在与要被调整以校正反射率变化的多个喷嘴中与每个喷嘴相关联的打印头补偿值相关联的存储器中。

公开(公告)号：US20050185343A1

公开(公告)日：2005-08-25

申请号：US10784506

申请日：2004-02-23

申请人： Parul Agrawal ,  Hang Ngo ,  Charles Lee ,  Li-Chung Lee ,  Ullal Nayak ,  Stephen Olson ,  Robert Payne ,  Christopher Ramm

发明人： Parul Agrawal ,  Hang Ngo ,  Charles Lee ,  Li-Chung Lee ,  Ullal Nayak ,  Stephen Olson ,  Robert Payne ,  Christopher Ramm

IPC分类号： G01B5/28 ,  G11B5/60 ,  G11B15/64

CPC分类号： G11B5/6005

摘要： An air bearing burnish slider burnishes very small asperities and cleans the loose particles that adhere to the magnetic recording media. The slider applies a controllable contact force to effectively burnish disk asperities or partially attached particles. In addition, the slider cleans the loose particles effectively while flying in a stable fashion. In a low pitch design, diagonal rails push particles away from the disk surface and trailing edge pads contact the disk at lower linear velocities. Rail pads retain loose contamination and debris in their pockets and burnish asperities. Another design provides a milder burnish force and flies in a high pitch configuration. The trailing edge pads provide stable contacts and the rails help in sweeping away debris. In both designs, the contact forces can be controlled by adjusting linear velocities. A step taper at the leading edge provides a pitch-producing lift force.

摘要翻译： 空气轴承抛光滑块抛光非常小的凹凸，并清洁附着在磁记录介质上的松散颗粒。 滑块应用可控的接触力来有效地抛光磁盘粗糙度或部分附着的颗粒。 此外，滑块可以以稳定的方式有效地清洁松散的颗粒。 在低间距设计中，斜轨将颗粒推离盘表面，后缘垫以较低的线速度接触盘。 轨道垫在其口袋中保持松散的污染和碎屑，并且消除粗糙。 另一种设计提供更温和的抛光力并以高间距配置飞行。 后缘垫提供稳定的触点，导轨有助于扫除碎屑。 在这两种设计中，接触力可以通过调整线性速度来控制。 在前缘的阶梯锥形提供产生俯仰的提升力。

公开(公告)号：US20120266260A1

公开(公告)日：2012-10-18

申请号：US13321025

申请日：2010-05-26

申请人： Hitoshi Suzuki ,  Run Fan ,  Bruce A. Julian ,  Jan Novak ,  Zina Moldoveanu ,  Zhixin Zhang ,  Milan Tomana ,  Jiri Mestecky ,  Robert J. Wyatt ,  Yasuhiko Tomino ,  Yusuke Suzuki ,  Stephen Olson

发明人： Hitoshi Suzuki ,  Run Fan ,  Bruce A. Julian ,  Jan Novak ,  Zina Moldoveanu ,  Zhixin Zhang ,  Milan Tomana ,  Jiri Mestecky ,  Robert J. Wyatt ,  Yasuhiko Tomino ,  Yusuke Suzuki ,  Stephen Olson

IPC分类号： A61K39/395 ,  G01N33/566 ,  C12Q1/68 ,  G01N21/76 ,  C07K16/00 ,  C07K16/42 ,  A01K67/00 ,  A61K35/16 ,  A61P13/12 ,  G01N21/78 ,  C40B30/04

CPC分类号： A61K39/39541 ,  C07K16/4283 ,  C07K2317/41 ,  C07K2317/55 ,  C07K2317/565 ,  G01N33/6854 ,  G01N33/6893 ,  G01N2800/347

摘要： Provided are methods of diagnosing IgA nephropathy in a subject. Optionally, the methods comprise isolating an IgG from the subject and determining whether the IgG binds to a galactose-deficient IgA1. Optionally, the methods comprise providing a biological sample from the subject and detecting in the sample a mutation in a IGH gene, wherein the mutation is in a nucleotide sequence encoding a complementarity determining region 3 (CDR3) of a IGH variable region. Optionally, the methods comprise determining a level of IgG specific for a galactose-deficient IgA1 in the subject. Also provided are methods of treating or reducing the risk of developing IgA nephropathy in a subject.

摘要翻译： 提供了诊断受试者中IgA肾病的方法。 任选地，所述方法包括从受试者中分离IgG并确定IgG是否结合到半乳糖缺乏型IgA1。 任选地，所述方法包括提供来自受试者的生物样品，并在样品中检测IGH基因中的突变，其中突变位于编码IGH可变区的互补决定区3（CDR3）的核苷酸序列中。 任选地，所述方法包括测定受试者中对半乳糖缺乏型IgA1具有特异性的IgG水平。 还提供了治疗或降低受试者中发生IgA肾病风险的方法。

公开(公告)号：US20070252862A1

公开(公告)日：2007-11-01

申请号：US11775646

申请日：2007-07-10

申请人： Stephen Olson

发明人： Stephen Olson

IPC分类号： B41J29/393 ,  G05D1/02

CPC分类号： B41J29/393

摘要： A method of determining unidirectional print direction for optimal quality on an ink jet printer capable of bidirectional printing includes printing a first plurality of indicators on a recordable medium, wherein the first plurality of indicators are printed in a first direction; printing a second plurality of indicators on the recordable medium, wherein the second plurality of indicators are printed in a second direction opposite the first direction; and determining an optimum print direction from the printed indicators; and setting in the printer the optimum print direction for unidirectional printing.

摘要翻译： 一种在能够双向打印的喷墨打印机上确定最佳质量的单向打印方向的方法包括在可记录介质上印刷第一多个指示符，其中第一多个指示符以第一方向打印; 在所述可记录介质上印刷第二多个指示符，其中所述第二多个指示符以与所述第一方向相反的第二方向打印; 以及从印刷的指示器确定最佳打印方向; 并在打印机中设置单向打印的最佳打印方向。

公开(公告)号：US20070128956A1

公开(公告)日：2007-06-07

申请号：US11539526

申请日：2006-10-06

申请人： Charles BLAIR ,  Stephen Olson

发明人： Charles BLAIR ,  Stephen Olson

IPC分类号： B63H21/21

CPC分类号： B63H21/213

摘要： A torsional throttle control system is provided that may include any of a number of features. One feature of the throttle control system is twist-style grip that has an axis with an angle adjustable to a housing. Another feature comprises trim and/or outboard motor control(s) atop the grip. Yet another feature comprises the internal mechanism adapted to effect throttle control. Methods associated with use of the throttle control hardware and systems including a boat are also covered.

摘要翻译： 提供了可以包括多个特征中的任何一个的扭转节流控制系统。 节气门控制系统的一个特征是扭转式握柄，其具有可与壳体可调节的角度的轴线。 另一个特征包括在把手顶部的修剪和/或舷外马达控制。 另一个特征包括适于实现油门控制的内部机构。 还涉及与使用节流控制硬件和包括船的系统有关的方法。

公开(公告)号：US20060282106A1

公开(公告)日：2006-12-14

申请号：US10299582

申请日：2002-11-18

申请人： David Cole ,  Darin Gittings ,  Stephen Olson ,  Dean Carson ,  Michael Reo ,  Keke Lepulu ,  A. Sharkawy

发明人： David Cole ,  Darin Gittings ,  Stephen Olson ,  Dean Carson ,  Michael Reo ,  Keke Lepulu ,  A. Sharkawy

IPC分类号： A61B17/08

CPC分类号： A61B17/0643 ,  A61B17/00491 ,  A61B17/0057 ,  A61B17/0469 ,  A61B17/064 ,  A61B17/0644 ,  A61B17/068 ,  A61B17/11 ,  A61B2017/00252 ,  A61B2017/00575 ,  A61B2017/00592 ,  A61B2017/00606 ,  A61B2017/00876 ,  A61B2017/1107 ,  A61B2017/1135 ,  A61B2017/1139 ,  A61F2/064 ,  A61F2002/30079 ,  A61F2210/009 ,  H01F7/0242

摘要： An anastomosis device has first and second components which each having first and second parts. The first and second components are magnetically attracted to one another. The device forms a throughhole when in use. The first parts of the first and second components are positioned radially outward from the second parts relative to the longitudinal axis with the first parts of the first and second components contacting one another and being magnetically attracted to one another. The second parts of the first and second components also being magnetically attracted to one another and are separated by the vessel walls.

公开(公告)号：US20100121349A1

公开(公告)日：2010-05-13

申请号：US12577044

申请日：2009-10-09

申请人： Stephen C. Meier ,  Eugene Serina ,  Charles J. Adam ,  Mariel Fabro ,  Tammy Y. Tam ,  John P. Lunsford ,  Tenny C. Calhoun ,  Brian Tang ,  Stephen Olson ,  Ann T. Meier

发明人： Stephen C. Meier ,  Eugene Serina ,  Charles J. Adam ,  Mariel Fabro ,  Tammy Y. Tam ,  John P. Lunsford ,  Tenny C. Calhoun ,  Brian Tang ,  Stephen Olson ,  Ann T. Meier

IPC分类号： A61B17/04

CPC分类号： A61B17/0487 ,  A61B17/0467 ,  A61B17/0485 ,  A61B17/0644 ,  A61B17/068 ,  A61B17/083 ,  A61B17/10 ,  A61B2017/00243 ,  A61B2017/00783 ,  A61B2017/045 ,  A61B2017/0451 ,  A61B2017/0488 ,  A61B2017/0496 ,  A61B2017/320052

摘要： Devices and methods for locking and/or cutting tethers during a tissue modification procedure are described. In some variations, a tether may be used to tighten tissue by bringing two pieces or sections of the tissue together. The tether, which may be under tension, may be locked to maintain the tension, and excess tether may be severed, using one or more of the devices and/or methods. The devices and/or methods may be used, for example, in minimally invasive procedures.

摘要翻译： 描述了在组织修改过程中锁定和/或切割系绳的装置和方法。 在一些变型中，系绳可以用于通过将组织的两个或多个部分组合在一起来收紧组织。 可能处于张力下的系绳可以被锁定以保持张力，并且可以使用一种或多种装置和/或方法来切断多余的系绳。 装置和/或方法可以用于例如微创程序。

公开(公告)号：US07164557B2

公开(公告)日：2007-01-16

申请号：US10784506

申请日：2004-02-23

申请人： Parul Agrawal ,  Hang Fai Ngo ,  Charles Lee ,  Li-Chung Lee ,  Ullal Vasant Nayak ,  Stephen Olson ,  Robert N. Payne ,  Christopher Ramm

发明人： Parul Agrawal ,  Hang Fai Ngo ,  Charles Lee ,  Li-Chung Lee ,  Ullal Vasant Nayak ,  Stephen Olson ,  Robert N. Payne ,  Christopher Ramm

IPC分类号： G11B5/60

CPC分类号： G11B5/6005

摘要： An air bearing burnish slider burnishes very small asperities and cleans the loose particles that adhere to the magnetic recording media. The slider applies a controllable contact force to effectively burnish disk asperities or partially attached particles. In addition, the slider cleans the loose particles effectively while flying in a stable fashion. In a low pitch design, diagonal rails push particles away from the disk surface and trailing edge pads contact the disk at lower linear velocities. Rail pads retain loose contamination and debris in their pockets and burnish asperities. Another design provides a milder burnish force and flies in a high pitch configuration. The trailing edge pads provide stable contacts and the rails help in sweeping away debris. In both designs, the contact forces can be controlled by adjusting linear velocities. A step taper at the leading edge provides a pitch-producing lift force.

摘要翻译： 空气轴承抛光滑块抛光非常小的凹凸，并清洁附着在磁记录介质上的松散颗粒。 滑块应用可控的接触力来有效地抛光磁盘粗糙度或部分附着的颗粒。 此外，滑块可以以稳定的方式有效地清洁松散的颗粒。 在低间距设计中，斜轨将颗粒推离盘表面，后缘垫以较低的线速度接触盘。 轨道垫在其口袋中保持松散的污染和碎屑，并且消除粗糙。 另一种设计提供更温和的抛光力并以高间距配置飞行。 后缘垫提供稳定的触点，导轨有助于扫除碎屑。 在这两种设计中，接触力可以通过调整线性速度来控制。 在前缘的阶梯锥形提供产生俯仰的提升力。

公开(公告)号：US20060066658A1

公开(公告)日：2006-03-30

申请号：US10956927

申请日：2004-09-30

申请人： Stephen Olson

发明人： Stephen Olson

IPC分类号： B41J29/393

CPC分类号： B41J29/393

摘要： A method of determining unidirectional print direction for optimal quality on an ink jet printer capable of bidirectional printing includes printing a first plurality of indicators on a recordable medium, wherein the first plurality of indicators are printed in a first direction; printing a second plurality of indicators on the recordable medium, wherein the second plurality of indicators are printed in a second direction opposite the first direction; and determining an optimum print direction from the printed indicators; and setting in the printer the optimum print direction for unidirectional printing.

摘要翻译： 一种在能够双向打印的喷墨打印机上确定最佳质量的单向打印方向的方法包括在可记录介质上印刷第一多个指示符，其中第一多个指示符以第一方向打印; 在所述可记录介质上印刷第二多个指示符，其中所述第二多个指示符以与所述第一方向相反的第二方向打印; 以及从印刷的指示器确定最佳打印方向; 并在打印机中设置单向打印的最佳打印方向。