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公开(公告)号：US20170363600A9
公开(公告)日：2017-12-21
申请号：US15372248
申请日：2016-12-07
申请人： Steve M. Savoy , Kyle W. Hoover , Daniel R. Mitchell , Jeremy J. John , Chris W. Mann , Alexander P. Greis
发明人： Steve M. Savoy , Kyle W. Hoover , Daniel R. Mitchell , Jeremy J. John , Chris W. Mann , Alexander P. Greis
IPC分类号： G01N33/00
CPC分类号： G01N33/0036 , G01N27/125
摘要： Methods and sensors for detection and quantification of one or more analyte in a test sample are described. A response profile of a gas sensor to a control sample of a known interrogator gas is determined. The gas sensor is exposed to a test sample then to a second sample comprising the known interrogator gas, and a test sample response profile of the gas sensor is determined. One or more test sample sensor response profiles are compared with one or more control sensor response profiles for detecting, identifying, and quantifying one or more analytes in the test sample.
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公开(公告)号：US20170160250A1
公开(公告)日：2017-06-08
申请号：US15372248
申请日：2016-12-07
申请人： Steve M. Savoy , Kyle W. Hoover , Daniel R. Mitchell , Jeremy J. John , Chris W. Mann , Alexander P. Greis
发明人： Steve M. Savoy , Kyle W. Hoover , Daniel R. Mitchell , Jeremy J. John , Chris W. Mann , Alexander P. Greis
IPC分类号： G01N33/00
CPC分类号： G01N33/0036 , G01N27/125
摘要： Methods and sensors for detection and quantification of one or more analyte in a test sample are described. A response profile of a gas sensor to a control sample of a known interrogator gas is determined. The gas sensor is exposed to a test sample then to a second sample comprising the known interrogator gas, and a test sample response profile of the gas sensor is determined. One or more test sample sensor response profiles are compared with one or more control sensor response profiles for detecting, identifying, and quantifying one or more analytes in the test sample.
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公开(公告)号：US20170160227A1
公开(公告)日：2017-06-08
申请号：US15372343
申请日：2016-12-07
申请人： Steve M. Savoy , Kyle W. Hoover , Chris W. Mann , Daniel R. Mitchell , Jeremy J. John , Alexander P. Greis
发明人： Steve M. Savoy , Kyle W. Hoover , Chris W. Mann , Daniel R. Mitchell , Jeremy J. John , Alexander P. Greis
IPC分类号： G01N27/414 , G01N33/543
CPC分类号： G01N33/54373
摘要： Methods and sensors for detection and quantification of one or more analyte in a test sample are described. A response profile of an ion sensor to a control sample of a known interrogator ion is determined. The ion sensor is exposed to a test sample then to a second sample comprising the known interrogator ion, and a test sample response profile of the ion sensor is determined. One or more test sample sensor response profiles are compared with one or more control sensor response profiles for detecting, identifying, and quantifying one or more analytes in the test sample.
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4.发明申请公开(公告)号：US20170343538A9
公开(公告)日：2017-11-30
申请号：US15372075
申请日：2016-12-07
申请人： Steve M. Savoy , Kyle W. Hoover , Daniel R. Mitchell , Jeremy J. John , Chris W. Mann , Alexander P. Greis
发明人： Steve M. Savoy , Kyle W. Hoover , Daniel R. Mitchell , Jeremy J. John , Chris W. Mann , Alexander P. Greis
IPC分类号： G01N33/53 , G01N33/497 , G01N33/00
CPC分类号： G01N33/5308 , G01N33/0008 , G01N33/0031 , G01N33/0047 , G01N33/497 , G01N2033/4975
摘要： Methods and sensors for the detection, identification, and quantification of one or more gas species, including volatile organic compounds, in a test sample are described. Methods employ gas sensors comprising a diffusion matrix present on the sensor surface. A gas analyte in a test sample diffuses through the matrix and is detected upon interaction of the analyte with the sensor. A response profile of a gas sensor to a gas analyte in the test sample is compared to a control gas sensor response profile determined in a similar manner for a known gas species. Comparisons of test sample and control sample sensor response profiles enable detection, identification, and quantification of a gas species analyte in a test sample.
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5.发明申请公开(公告)号：US20170160221A1
公开(公告)日：2017-06-08
申请号：US15372075
申请日：2016-12-07
申请人： Steve M. Savoy , Kyle W. Hoover , Daniel R. Mitchell , Jeremy J. John , Chris W. Mann , Alexander P. Greis
发明人： Steve M. Savoy , Kyle W. Hoover , Daniel R. Mitchell , Jeremy J. John , Chris W. Mann , Alexander P. Greis
IPC分类号： G01N27/12 , G01N33/497 , G01N33/53 , G01N33/00
CPC分类号： G01N33/5308 , G01N33/0008 , G01N33/0031 , G01N33/0047 , G01N33/497 , G01N2033/4975
摘要： Methods and sensors for the detection, identification, and quantification of one or more gas species, including volatile organic compounds, in a test sample are described. Methods employ gas sensors comprising a diffusion matrix present on the sensor surface. A gas analyte in a test sample diffuses through the matrix and is detected upon interaction of the analyte with the sensor. A response profile of a gas sensor to a gas analyte in the test sample is compared to a control gas sensor response profile determined in a similar manner for a known gas species. Comparisons of test sample and control sample sensor response profiles enable detection, identification, and quantification of a gas species analyte in a test sample.
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公开(公告)号：US08450131B2
公开(公告)日：2013-05-28
申请号：US13004381
申请日：2011-01-11
IPC分类号： G01N27/414 , H01L27/088 , H01L21/203 , H01L29/06
CPC分类号： H01L27/088 , B82Y99/00 , G01N27/4148 , H01L27/1462 , H01L29/0673 , Y10S977/762
摘要： An array of sensor devices, each sensor including a set of semiconducting nanotraces having a width less than about 100 nm is provided. Method for fabricating the arrays is disclosed, providing a top-down approach for large arrays with multiple copies of the detection device in a single processing step. Nanodimensional sensing elements with precise dimensions and spacing to avoid the influence of electrodes are provided. The arrays may be used for multiplex detection of chemical and biomolecular species. The regular arrays may be combined with parallel synthesis of anchor probe libraries to provide a multiplex diagnostic device. Applications for gas phase sensing, chemical sensing and solution phase biomolecular sensing are disclosed.
摘要翻译： 提供一组传感器装置，每个传感器包括一组宽度小于约100nm的半导体纳米管。 公开了用于制造阵列的方法，在单个处理步骤中为检测装置的多个拷贝的大阵列提供自上而下的方法。 提供具有精确尺寸和间隔的避免电极影响的纳米感测元件。 阵列可用于化学和生物分子物种的多重检测。 常规阵列可以与锚探针库的并行合成组合以提供多路诊断装置。 公开了用于气相感测，化学感测和溶液相生物分子感测的应用。
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公开(公告)号：US10550494B2
公开(公告)日：2020-02-04
申请号：US15791403
申请日：2017-10-23
摘要： Analyte filter arrays and methods for making an analyte filter array are provided. The arrays are formed using a dispersion of filter particles having selected moieties attached to the surface of the particles and a microarray having complementary moieties formed in an array on a substrate, such that each filter particle is attached to a selected region of the microarray. The moiety on the substrate may be RNA or DNA or other molecule. The substrate may be a surface of a detector array, a membrane that may be placed in registration with the detector array or a stamp used to transfer the filter array to a detector array.
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公开(公告)号：US09252175B2
公开(公告)日：2016-02-02
申请号：US13069928
申请日：2011-03-23
CPC分类号： H01L27/14625 , H01L27/14685
摘要： Spectroscopic filter arrays and methods for making spectroscopic filter arrays are provided. The arrays are formed using a dispersion of filter particles having selected moieties attached to the surface of the particles and a microarray having complementary moieties formed in an array on a substrate, such that each filter particle is attached to a selected region of the microarray. The moiety on the substrate may be RNA or DNA or other molecule. The substrate may be a surface of a photodetector array, a transparent plate that may be placed in registration with the photodetector or a stamp used to transfer the filter array to a photodetector array.
摘要翻译： 提供光谱过滤器阵列和制造分光过滤器阵列的方法。 使用具有连接到颗粒表面的选定部分的过滤颗粒的分散体和在基底上形成有阵列的互补部分的微阵列形成阵列，使得每个过滤颗粒附着到微阵列的选定区域。 底物上的部分可以是RNA或DNA或其他分子。 基板可以是光电检测器阵列的表面，可以放置成与光电检测器对准的透明板或用于将滤光器阵列传送到光电检测器阵列的印模。
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公开(公告)号：US20120245055A1
公开(公告)日：2012-09-27
申请号：US13070077
申请日：2011-03-23
CPC分类号： C40B50/18 , B01J19/0046 , B01J2219/00382 , B01J2219/00576 , B01J2219/00637 , B01J2219/00648 , B01J2219/00722
摘要： Analyte filter arrays and methods for making an analyte filter array are provided. The arrays are formed using a dispersion of filter particles having selected moieties attached to the surface of the particles and a microarray having complementary moieties formed in an array on a substrate, such that each filter particle is attached to a selected region of the microarray. The moiety on the substrate may be RNA or DNA or other molecule. The substrate may be a surface of a detector array, a membrane that may be placed in registration with the detector array or a stamp used to transfer the filter array to a detector array.
摘要翻译： 提供了分析物过滤器阵列和用于制备分析物过滤器阵列的方法。 使用具有连接到颗粒表面的选定部分的过滤颗粒的分散体和在基底上形成有阵列的互补部分的微阵列形成阵列，使得每个过滤颗粒附着到微阵列的选定区域。 底物上的部分可以是RNA或DNA或其他分子。 衬底可以是检测器阵列的表面，可以放置成与检测器阵列对准的膜或用于将过滤器阵列传送到检测器阵列的标记。
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公开(公告)号：US20180051390A1
公开(公告)日：2018-02-22
申请号：US15791403
申请日：2017-10-23
CPC分类号： C40B50/18 , B01J19/0046 , B01J2219/00382 , B01J2219/00576 , B01J2219/00637 , B01J2219/00648 , B01J2219/00722
摘要： Analyte filter arrays and methods for making an analyte filter array are provided. The arrays are formed using a dispersion of filter particles having selected moieties attached to the surface of the particles and a microarray having complementary moieties formed in an array on a substrate, such that each filter particle is attached to a selected region of the microarray. The moiety on the substrate may be RNA or DNA or other molecule. The substrate may be a surface of a detector array, a membrane that may be placed in registration with the detector array or a stamp used to transfer the filter array to a detector array.
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