公开(公告)号：US5630986A

公开(公告)日：1997-05-20

申请号：US404303

申请日：1995-03-14

申请人： Steven C. Charlton ,  Anne T. Miller ,  Joseph L. Moulton ,  Matthew A. Schumann ,  Dennis Slomski ,  Frank W. Wogoman

发明人： Steven C. Charlton ,  Anne T. Miller ,  Joseph L. Moulton ,  Matthew A. Schumann ,  Dennis Slomski ,  Frank W. Wogoman

IPC分类号： G01N33/66 ,  B01L99/00 ,  G01N27/28 ,  G01N27/327 ,  G01N33/487 ,  G01N35/00 ,  G01N37/00

CPC分类号： G01N33/4875 ,  B01L99/00 ,  G01N2035/00089 ,  Y10T436/11 ,  Y10T436/110833 ,  Y10T436/112499

摘要： A sensor dispensing instrument is adapted to receive a generally circular sensor pack containing a plurality of blood glucose sensors. Each of the sensors are disposed in sensor cavities, each of which is in fluid communication with a corresponding desiccant cavity and has a support wall that assists in directing the sensor as its being ejected from the cavity. The sensor pack is loaded on an indexing disk in the instrument such that when a slide actuator on the instrument is moved toward a testing position, a feed mechanism engaged by the slide actuator moves a knife blade thereon toward one of the sensor cavities. The knife blade pierces a portion of a foil covering the sensor cavity and engages the sensor disposed in the cavity to thereby eject the sensor from the sensor cavity. The continued sliding of the slide actuator toward its testing position results in the sensor being completely ejected from the sensor cavity and disposed in a testing position with a testing end of the sensor projecting from the instrument. Once the blood analyzing test is completed, the slide actuator is moved in the opposite direction towards its standby position. As the slide actuator is moved away from its testing position, the indexing disk with the sensor pack thereon is rotated so that the next one of sensor cavities is positioned so that the sensor therein can be used for the next blood glucose test that is to be performed. The instrument includes circuitry to obtain test data from the sensor pack and to display testing data.

摘要翻译： 传感器分配仪器适于接收包含多个血糖传感器的大体上圆形的传感器组件。 每个传感器设置在传感器腔中，每个传感器腔与相应的干燥剂腔流体连通，并且具有支撑壁，该支撑壁有助于将传感器从空腔喷射出来。 传感器组件被装载在仪器中的分度盘上，使得当仪器上的滑块致动器朝向测试位置移动时，由滑动致动器接合的进给机构将其上的刀片向着其中一个传感器腔移动。 刀片刺穿覆盖传感器腔的箔片的一部分，并接合设置在空腔中的传感器，从而将传感器从传感器腔排出。 滑动致动器朝向其测试位置的持续滑动导致传感器从传感器腔完全弹出并且设置在测试位置，传感器的测试端从仪器突出。 一旦血液分析测试完成，滑动致动器就朝向其待机位置的相反方向移动。 当滑块致动器从其测试位置移开时，其上具有传感器组件的分度盘被旋转，使得下一个传感器腔被定位成使得其中的传感器可用于下一次血糖测试 执行。 仪器包括从传感器组件获取测试数据并显示测试数据的电路。

公开(公告)号：US5738244A

公开(公告)日：1998-04-14

申请号：US660874

申请日：1996-06-10

申请人： Steven C. Charlton ,  Anne T. Miller ,  Joseph L. Moulton ,  Matthew A. Schumann ,  Dennis Slomski ,  Frank W. Wogoman

发明人： Steven C. Charlton ,  Anne T. Miller ,  Joseph L. Moulton ,  Matthew A. Schumann ,  Dennis Slomski ,  Frank W. Wogoman

IPC分类号： B01L99/00 ,  G01N33/487 ,  G01N35/00 ,  G01N37/00 ,  B65H3/58

CPC分类号： G01N33/4875 ,  B01L99/00 ,  G01N2035/00089 ,  Y10S206/828

摘要： A sensor dispensing instrument is adapted to receive a generally circular sensor pack containing a plurality of blood glucose sensors. Each of the sensors are disposed in sensor cavities, each of which is in fluid communication with a corresponding desiccant cavity and has a support wall that assists in directing the sensor as its being ejected from the cavity. The sensor pack is loaded on an indexing disk in the instrument such that when a slide actuator on the instrument is moved toward a testing position, a feed mechanism engaged by the slide actuator moves a knife blade thereon toward one of the sensor cavities. The knife blade pierces a portion of a foil covering the sensor cavity and engages the sensor disposed in the cavity to thereby eject the sensor from the sensor cavity. The continued sliding of the slide actuator toward its testing position results in the sensor being completely ejected from the sensor cavity and disposed in a testing position with a testing end of the sensor projecting from the instrument. Once the blood analyzing test is completed, the slide actuator is moved in the opposite direction towards its standby position. As the slide actuator is moved away from its testing position, the indexing disk with the sensor pack thereon is rotated so that the next one of sensor cavities is positioned so that the sensor therein can be used for the next blood glucose test that is to be performed. The instrument includes circuitry to obtain test data from the sensor pack and to display testing data.

公开(公告)号：US5854074A

公开(公告)日：1998-12-29

申请号：US785185

申请日：1997-01-17

申请人： Steven C. Charlton ,  Anne T. Miller ,  Joseph L. Moulton ,  Matthew A. Schumann ,  Dennis Slomski ,  Frank W. Wogoman

发明人： Steven C. Charlton ,  Anne T. Miller ,  Joseph L. Moulton ,  Matthew A. Schumann ,  Dennis Slomski ,  Frank W. Wogoman

IPC分类号： G01N33/66 ,  B01L99/00 ,  G01N27/28 ,  G01N27/327 ,  G01N33/487 ,  G01N35/00 ,  G01N37/00

CPC分类号： G01N33/4875 ,  B01L99/00 ,  G01N2035/00089 ,  Y10T436/11 ,  Y10T436/110833 ,  Y10T436/112499

摘要： A sensor dispensing instrument is adapted to receive a generally circular sensor pack containing a plurality of blood glucose sensors. Each of the sensors are disposed in sensor cavities, each of which is in fluid communication with a corresponding desiccant cavity and has a support wall that assists in directing the sensor as its being ejected from the cavity. The sensor pack is loaded on an indexing disk in the instrument such that when a slide actuator on the instrument is moved toward a testing position, a feed mechanism engaged by the slide actuator moves a knife blade thereon toward one of the sensor cavities. The knife blade pierces a portion of a foil covering the sensor cavity and engages the sensor disposed in the cavity to thereby eject the sensor from the sensor cavity. The continued sliding of the slide actuator toward its testing position results in the sensor being completely ejected from the sensor cavity and disposed in a testing position with a testing end of the sensor projecting from the instrument. Once the blood analyzing test is completed, the slide actuator is moved in the opposite direction towards its standby position. As the slide actuator is moved away from its testing position, the indexing disk with the sensor pack thereon is rotated so that the next one of sensor cavities is positioned so that the sensor therein can be used for the next blood glucose test that is to be performed. The instrument includes circuitry to obtain test data from the sensor pack and to display testing data.

公开(公告)号：US5810199A

公开(公告)日：1998-09-22

申请号：US927134

申请日：1997-09-02

申请人： Steven C. Charlton ,  Anne T. Miller ,  Joseph L. Moulton ,  Matthew A. Schumann ,  Dennis Slomski ,  Frank W. Wogoman

发明人： Steven C. Charlton ,  Anne T. Miller ,  Joseph L. Moulton ,  Matthew A. Schumann ,  Dennis Slomski ,  Frank W. Wogoman

IPC分类号： G01N33/487 ,  G07F11/72

CPC分类号： G01N33/4875

摘要： A sensor dispensing instrument is adapted to receive a generally circular sensor pack containing a plurality of blood glucose sensors. Each of the sensors are disposed in sensor cavities, each of which is in fluid communication with a corresponding desiccant cavity and has a support wall that assists in directing the sensor as its being ejected from the cavity. The sensor pack is loaded on an indexing disk in the instrument such that when a slide actuator on the instrument is moved toward a testing position, a feed mechanism engaged by the slide actuator moves a knife blade thereon toward one of the sensor cavities. The knife blade pierces a portion of a foil covering the sensor cavity and engages the sensor disposed in the cavity to thereby eject the sensor from the sensor cavity. The continued sliding of the slide actuator toward its testing position results in the sensor being completely ejected from the sensor cavity and disposed in a testing position with a testing end of the sensor projecting from the instrument. Once the blood analyzing test is completed, the slide actuator is moved in the opposite direction towards its standby position. As the slide actuator is moved away from its testing position, the indexing disk with the sensor pack thereon is rotated so that the next one of sensor cavities is positioned so that the sensor therein can be used for the next blood glucose test that is to be performed. The instrument includes circuitry to obtain test data from the sensor pack and to display testing data.

摘要翻译： 传感器分配仪器适于接收包含多个血糖传感器的大体上圆形的传感器组件。 每个传感器设置在传感器腔中，每个传感器腔与相应的干燥剂腔流体连通，并且具有支撑壁，该支撑壁有助于将传感器从空腔喷射出来。 传感器组件被装载在仪器中的分度盘上，使得当仪器上的滑块致动器朝向测试位置移动时，由滑动致动器接合的进给机构将其上的刀片向着其中一个传感器腔移动。 刀片刺穿覆盖传感器腔的箔片的一部分，并接合设置在空腔中的传感器，从而将传感器从传感器腔排出。 滑动致动器朝向其测试位置的持续滑动导致传感器从传感器腔完全弹出并且设置在测试位置，传感器的测试端从仪器突出。 一旦血液分析测试完成，滑动致动器就朝向其待机位置的相反方向移动。 当滑块致动器从其测试位置移开时，其上具有传感器组件的分度盘被旋转，使得下一个传感器腔被定位成使得其中的传感器可用于下一次血糖测试 执行。 仪器包括从传感器组件获取测试数据并显示测试数据的电路。

公开(公告)号：US5575403A

公开(公告)日：1996-11-19

申请号：US372304

申请日：1995-01-13

申请人： Steven C. Charlton ,  Anne T. Miller ,  Joseph L. Moulton ,  Matthew A. Schumann ,  Dennis Slomski ,  Frank W. Wogoman

发明人： Steven C. Charlton ,  Anne T. Miller ,  Joseph L. Moulton ,  Matthew A. Schumann ,  Dennis Slomski ,  Frank W. Wogoman

IPC分类号： B01L99/00 ,  G01N33/487 ,  G01N35/00 ,  G01N37/00 ,  G07F11/72

CPC分类号： G01N33/4875 ,  B01L99/00 ,  G01N2035/00089 ,  Y10S206/828

摘要： A sensor dispensing instrument is adapted to receive a generally circular sensor pack containing a plurality of blood glucose sensors. Each of the sensors are disposed in sensor cavities, each of which is in fluid communication with a corresponding desiccant cavity and has a support wall that assists in directing the sensor as its being ejected from the cavity. The sensor pack is loaded on an indexing disk in the instrument such that when a slide actuator on the instrument is moved toward a testing position, a feed mechanism engaged by the slide actuator moves a knife blade thereon toward one of the sensor cavities. The knife blade pierces a portion of a foil covering the sensor cavity and engages the sensor disposed in the cavity to thereby eject the sensor from the sensor cavity. The continued sliding of the slide actuator toward its testing position results in the sensor being completely ejected from the sensor cavity and disposed in a testing position with a testing end of the sensor projecting from the instrument. Once the blood analyzing test is completed, the slide actuator is moved in the opposite direction towards its standby position. As the slide actuator is moved away from its testing position, the indexing disk with the sensor pack thereon is rotated so that the next one of sensor cavities is positioned so that the sensor therein can be used for the next blood glucose test that is to be performed. The instrument includes circuitry to obtain test data from the sensor pack and to display testing data.

摘要翻译： 传感器分配仪器适于接收包含多个血糖传感器的大体上圆形的传感器组件。 每个传感器设置在传感器腔中，每个传感器腔与相应的干燥剂腔流体连通，并且具有支撑壁，该支撑壁有助于将传感器从空腔喷射出来。 传感器组件被装载在仪器中的分度盘上，使得当仪器上的滑块致动器朝向测试位置移动时，由滑动致动器接合的进给机构将其上的刀片向着其中一个传感器腔移动。 刀片刺穿覆盖传感器腔的箔片的一部分，并接合设置在空腔中的传感器，从而将传感器从传感器腔排出。 滑动致动器朝向其测试位置的持续滑动导致传感器从传感器腔完全弹出并且设置在测试位置，传感器的测试端从仪器突出。 一旦血液分析测试完成，滑动致动器就朝向其待机位置的相反方向移动。 当滑块致动器从其测试位置移开时，其上具有传感器组件的分度盘被旋转，使得下一个传感器腔被定位成使得其中的传感器可用于下一次血糖测试 执行。 仪器包括从传感器组件获取测试数据并显示测试数据的电路。

公开(公告)号：US5798031A

公开(公告)日：1998-08-25

申请号：US854439

申请日：1997-05-12

申请人： Steven C. Charlton ,  Larry D. Johnson ,  Matthew K. Musho ,  Dennis Slomski

发明人： Steven C. Charlton ,  Larry D. Johnson ,  Matthew K. Musho ,  Dennis Slomski

IPC分类号： G01N27/327 ,  C12Q1/00 ,  G01N27/26

CPC分类号： C12Q1/001 ,  G01N27/3272 ,  Y10S435/817 ,  Y10T156/1002 ,  Y10T156/1036 ,  Y10T156/1039 ,  Y10T156/1041

摘要： The present invention concerns an electrochemical sensor made up of an insulating base having an electrode layer on its surface and a lid of deformable material which comprises a concave area in the central portion thereof, so that when it is mated with the base, the lid and base form a capillary space containing the electrode layer. When the electrode layer is in operative contact with a reaction layer comprising an enzyme which will cause the production of mobile electrons when contacted with a suitable analyte, the concentration of analyte, e.g. glucose in blood, can be measured by measuring the current created by the flow of mobile electrons when contacted with a suitable analyte, the concentration of analyte, e.g. glucose in blood, can be measured by measuring the current created by the flow of mobile electrons.

摘要翻译： 本发明涉及一种电化学传感器，该电化学传感器由其表面上具有电极层的绝缘基底和可变形材料的盖构成，该绝缘基底在其中心部分包​​括凹形区域，使得当其与基底配合时， 基底形成包含电极层的毛细管空间。 当电极层与包含酶的反应层操作性接触时，该酶在与合适的分析物接触时将引起移动电子产生，分析物的浓度，例如浓度。 血液中的葡萄糖可以通过测量当与合适的分析物接触时移动电子流产生的电流，分析物的浓度，例如， 血液中的葡萄糖可以通过测量由流动电子流产生的电流来测量。

公开(公告)号：US08551418B2

公开(公告)日：2013-10-08

申请号：US13439477

申请日：2012-04-04

申请人： Sung-Kwon Jung ,  Steven C. Charlton

发明人： Sung-Kwon Jung ,  Steven C. Charlton

IPC分类号： G01N33/00

CPC分类号： A61B5/14532 ,  A61B2562/0295 ,  Y10T436/11 ,  Y10T436/110833

摘要： A system for analyzing the concentration of an analyte in a fluid sample comprises a test strip and a meter. The test strip is capable of being inoculated by the fluid sample. The test strip includes a test element, which contains at least one reagent adapted to cause a reaction when brought into contact with the analyte. The meter includes a read-head, a repositioning device, and a display. The read-head is capable of producing a signal indicative of the reaction between the analyte and the at least one reagent. The display is capable of displaying the analyte concentration. The repositioning device is adapted to move the test strip from a loading position to a testing position. The testing position positions the test element proximate to the read-head.

摘要翻译： 用于分析流体样品中分析物的浓度的系统包括测试条和仪表。 测试条能够被流体样品接种。 测试条包括测试元件，其包含至少一种适于在与分析物接触时引起反应的试剂。 仪表包括读取头，重新定位装置和显示器。 读取头能够产生指示分析物与至少一种试剂之间的反应的信号。 显示器能够显示分析物浓度。 重新定位装置适于将测试条从装载位置移动到测试位置。 测试位置使测试元件靠近读取头。

公开(公告)号：US08388827B2

公开(公告)日：2013-03-05

申请号：US13367801

申请日：2012-02-07

申请人： Dijia Huang ,  Steven C. Charlton ,  Suny J. George ,  Andrew J. Edelbrock

发明人： Dijia Huang ,  Steven C. Charlton ,  Suny J. George ,  Andrew J. Edelbrock

IPC分类号： G01N27/26 ,  G01N27/327 ,  G01F23/00 ,  G01R27/26

CPC分类号： G01N27/3272 ,  C12Q1/006 ,  G01N27/3274 ,  G01N27/3275 ,  G01N27/4163 ,  Y10T29/49082 ,  Y10T29/49099

摘要： According to one embodiment of the present invention, an electrochemical sensor (10) for detecting the concentration of analyte in a fluid test sample is disclosed. The sensor (10) includes a counter electrode having a high-resistance portion for use in detecting whether a predetermined amount of sample has been received by the test sensor.

摘要翻译： 根据本发明的一个实施例，公开了一种用于检测流体测试样品中分析物浓度的电化学传感器（10）。 传感器（10）包括具有高电阻部分的对电极，用于检测测试传感器是否已接收到预定量的样本。

公开(公告)号：US20130048495A1

公开(公告)日：2013-02-28

申请号：US13589377

申请日：2012-08-20

申请人： Steven C. Charlton

发明人： Steven C. Charlton

IPC分类号： G01N33/487 ,  G01N21/78 ,  B23P11/00

CPC分类号： G01N27/3273 ,  G01N27/3272 ,  G01N27/4166 ,  G01N33/48707 ,  G01N33/48757 ,  G01N33/48778 ,  G01N33/48785 ,  Y10T29/49826

摘要： In some aspects, an analyte sensor is provided for detecting an analyte concentration level in a biological fluid sample. The analyte sensor has a base including a top and bottom side, a lid, and an attachment member including one or more retention tabs coupled proximate the top side so that the analyte sensor can be grasped by the sensor's top side. Manufacturing methods and systems adapted to use and dispense the analyte sensors are provided, as are numerous other aspects.

摘要翻译： 在一些方面，提供了用于检测生物流体样品中的分析物浓度水平的分析物传感器。 分析物传感器具有包括顶部和底部侧面的底部，盖子和附接构件，该附接构件包括靠近顶侧连接的一个或多个保持翼片，使得分析物传感器能够被传感器的顶侧抓住。 与许多其它方面一样，提供了适于使用和分配分析物传感器的制造方法和系统。

公开(公告)号：US08251920B2

公开(公告)日：2012-08-28

申请号：US12686942

申请日：2010-01-13

申请人： Mark S. Vreeke ,  Scott L. Hoover ,  Steven C. Charlton ,  Larry D. Johnson

发明人： Mark S. Vreeke ,  Scott L. Hoover ,  Steven C. Charlton ,  Larry D. Johnson

IPC分类号： A61B5/00 ,  A61B17/14 ,  A61B17/32 ,  B65D81/00

CPC分类号： A61B5/157 ,  A61B5/14532 ,  A61B5/150022 ,  A61B5/150213 ,  A61B5/150442 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/15151 ,  A61B5/15174

摘要： An apparatus for lancing skin and collecting a liquid sample. The apparatus having a housing with an outer periphery and a rotatable arm having a lance to puncture the skin. A sample collection area is attached to the arm. The arm of the apparatus rotates from a first position to a second position. As the arm rotates, the lance extends beyond the housing allowing the lance to contact the user's skin and create a lance site. As the arm continues to move to the second position, the lance is brought out of contact with the user's skin and back within the housing while the collection area is brought into position. When the arm is located in the second position, the collection area is in substantially the same location as the lance site on the user's skin.

摘要翻译： 一种用于刺激皮肤并收集液体样品的装置。 该装置具有外周的外壳和可旋转的臂，其具有刺穿皮肤的喷枪。 样品收集区域连接到手臂。 设备的臂从第一位置旋转到第二位置。 当手臂旋转时，喷枪延伸超出外壳，允许喷枪与使用者的皮肤接触并创建喷枪部位。 当手臂继续移动到第二位置时，在将收集区域置于适当位置时，长矛与使用者的皮肤脱离接触并且在壳体内返回。 当臂位于第二位置时，收集区域与用户皮肤上的喷枪位置基本相同。