公开(公告)号：US06992170B2

公开(公告)日：2006-01-31

申请号：US09973424

申请日：2001-10-09

申请人： Sudhirdas K. Prayaga ,  Raymond J. Taupier, Jr. ,  Raj Bandaru

发明人： Sudhirdas K. Prayaga ,  Raymond J. Taupier, Jr. ,  Raj Bandaru

IPC分类号： C07K14/00 ,  C12P21/06 ,  A61K38/00

CPC分类号： C07K14/4725 ,  A61K38/00 ,  A61K39/00 ,  A61K48/00 ,  C07K14/57581 ,  C07K14/705

摘要： Disclosed herein are novel human nucleic acid sequences that have homology to thymosin, ephrin A receptors, proteoglycans and fibromodulin. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving these novel nucleic acids and proteins.

摘要翻译： 本文公开了与胸腺素，ephrin A受体，蛋白聚糖和纤维调节素具有同源性的新型人核酸序列。 还公开了由这些核酸序列编码的多肽，以及与多肽免疫特异性结合的抗体以及上述多肽，多核苷酸或抗体的衍生物，变体，突变体或片段。 本发明还公开了用于诊断，治疗和预防涉及这些新型核酸和蛋白质的病症的治疗，诊断和研究方法。

公开(公告)号：US06855806B1

公开(公告)日：2005-02-15

申请号：US09689486

申请日：2000-10-12

申请人： Sudhirdas K. Prayaga ,  Raymond J. Taupier, Jr. ,  Raj Bandaru

发明人： Sudhirdas K. Prayaga ,  Raymond J. Taupier, Jr. ,  Raj Bandaru

IPC分类号： G01N33/50 ,  A61K38/00 ,  A61K39/00 ,  A61K39/395 ,  A61K48/00 ,  A61P7/00 ,  A61P7/02 ,  A61P7/06 ,  A61P9/00 ,  A61P15/08 ,  A61P19/02 ,  A61P21/00 ,  A61P25/00 ,  A61P29/00 ,  A61P35/00 ,  A61P37/00 ,  A61P43/00 ,  C07K14/47 ,  C07K14/575 ,  C07K14/705 ,  C07K16/18 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N15/09 ,  C12P21/08 ,  C12Q1/68 ,  G01N33/15 ,  G01N33/53 ,  G01N33/566 ,  G01N33/577 ,  C07K14/00 ,  C12N5/00

CPC分类号： C07K14/705 ,  A61K38/00 ,  A61K39/00 ,  A61K48/00 ,  C07K14/4725 ,  C07K14/57581

摘要： Disclosed herein are novel human nucleic acid sequences. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving these novel nucleic acids and proteins.

摘要翻译： 本文公开了新的人核酸序列。 还公开了由这些核酸序列编码的多肽，以及与多肽免疫特异性结合的抗体以及上述多肽，多核苷酸或抗体的衍生物，变体，突变体或片段。 本发明还公开了用于诊断，治疗和预防涉及这些新型核酸和蛋白质的病症的治疗，诊断和研究方法。