公开(公告)号：US12076436B2

公开(公告)日：2024-09-03

申请号：US17737206

申请日：2022-05-05

Applicant: Symrise AG

Inventor： Andrew McShea ,  Katrina Nielsen ,  Joachim Hans ,  Mirjam Knupfer ,  Dominik Stuhlmann ,  Imke Meyer ,  Léa Schmidt ,  Marco Massironi ,  Francesca Benato ,  Sandro Rosa

IPC: A61K8/99 ,  A61K35/74 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q15/00 ,  A61Q19/00 ,  A61Q19/08 ,  A61Q19/10 ,  C12N1/20

CPC classification number: A61K8/99 ,  A61K35/74 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q15/00 ,  A61Q19/007 ,  A61Q19/08 ,  A61Q19/10 ,  C12N1/20

Abstract: A bacterial ferment obtained by a method including the following steps: (a) culturing Lactobacillus species in at least one growth medium for at least 24 hours; (b) separating the mixture via centrifugation; (c) adding lactic acid to the supernatant obtained from step b) in an amount sufficient to lower the pH value of the supernatant; (d) stabilizing the resulting mixture with the addition of at least one preservative and/or at least one multifunctional; and optionally (e) filtering the mixture to remove any final precipitation.

公开(公告)号：US20210069083A1

公开(公告)日：2021-03-11

申请号：US17090347

申请日：2020-11-05

Applicant: Symrise AG

Inventor： Imke Meyer ,  Mirjam Knupfer

IPC: A61K8/49 ,  A61Q17/04 ,  A61Q19/02 ,  A61Q5/00 ,  A61Q19/00 ,  A61K8/9789 ,  A61K8/31 ,  A61K8/33 ,  A61K8/34 ,  A61K8/35 ,  A61K8/37 ,  A61K8/44 ,  A61K8/58 ,  A61K8/60 ,  A61K8/67 ,  A61K8/92 ,  A61K31/365 ,  A61Q5/08

Abstract: Suggested is a method for improving skin whitening power of a skin whitening agent in a cosmetic or dietary supplement composition comprising or consisting of the following step: (a) providing a cosmetic composition comprising at least one skin whitening agent selected form the group consisting of kojic acid and phenylethyl resorcinol, beta- and alpha-arbutin, hydroquinone, nicotinamide, dioic acid, Mg ascorbyl phosphate and vitamin C and its derivatives, mulberry extract, Bengkoang extract, papaya extract, turmeric extract, nutgrass extract, licorice extract (containing glycyrrhizin), alpha-hydroxy-acids, 4-alkylresorcinols, 4-hydroxyanisole and mixtures thereof, and (b) adding a working amount of sclareolide to said composition.

公开(公告)号：US20170112736A1

公开(公告)日：2017-04-27

申请号：US15021489

申请日：2014-09-26

Applicant: Symrise AG

Inventor： Imke Meyer ,  Mirjam Knupfer ,  Holger Joppe ,  Antje Köhler ,  Bernd Hölscher ,  Marc Mansfeld

IPC: A61K8/34 ,  A61Q19/00 ,  A61Q17/04 ,  A61Q11/00 ,  A61Q5/02 ,  A61Q5/00 ,  A61Q15/00 ,  A61Q5/08 ,  A61Q19/08

CPC classification number: A61K8/345 ,  A61K2800/92 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/06 ,  A61Q5/08 ,  A61Q11/00 ,  A61Q15/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q19/08 ,  A61Q19/10

Abstract: Suggested is a composition comprising (a) larixol and at least one of the components (b1) to (b5) selected from (b1) tyrosinase inhibitors; (b2) sun protection factors; (b3) antioxidants; (b4) anti-inflammatory agents; and (b5) desquamating agents.

公开(公告)号：US09974721B2

公开(公告)日：2018-05-22

申请号：US15021489

申请日：2014-09-26

Applicant: Symrise AG

Inventor： Imke Meyer ,  Mirjam Knupfer ,  Holger Joppe ,  Antje Köhler ,  Bernd Hölscher ,  Marc Mansfeld

IPC: A61Q19/02 ,  A61K8/97 ,  A61K8/34 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/08 ,  A61Q11/00 ,  A61Q15/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/08 ,  A61Q5/06 ,  A61Q19/10

CPC classification number: A61K8/345 ,  A61K2800/92 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/06 ,  A61Q5/08 ,  A61Q11/00 ,  A61Q15/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q19/08 ,  A61Q19/10

Abstract: Suggested is a composition comprising (a) larixol and at least one of the components (b1) to (b5) selected from (b1) tyrosinase inhibitors; (b2) sun protection factors; (b3) antioxidants; (b4) anti-inflammatory agents; and (b5) desquamating agents.