-
公开(公告)号：US20180170874A1
公开(公告)日：2018-06-21
申请号：US15565891
申请日：2016-04-19
Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
Inventor： Yasutomi ASANO , Takuto KOJIMA , Osamu KURASAWA , Tzu-Tshin WONG , Yasuhiro HIRATA , Naoki IWAMURA , Bunnai SAITO , Yuta TANAKA , Ryosuke ARAI , Shinichi IMAMURA , Kazuko YONEMORI , Yasufumi MIYAMOTO , Shuji KITAMURA , Osamu SANO
IPC: C07D211/58 , C07D471/04 , C07D498/04 , C07D513/04 , C07D519/00 , C07D215/42 , C07D401/12 , C07D417/12 , C07D405/06 , C07D413/06 , C07D401/06 , C07D417/06 , C07D401/14 , C07D417/14 , C07D413/14 , C07B59/00 , A61P35/00 , A61P3/00
CPC classification number: C07D211/58 , A61K31/437 , A61K31/443 , A61K31/4433 , A61K31/4436 , A61K31/4439 , A61K31/444 , A61K31/4468 , A61K31/451 , A61K31/452 , A61K31/4709 , A61K31/498 , A61K31/506 , A61K31/517 , A61K31/5355 , A61K31/661 , A61K33/22 , A61P3/00 , A61P35/00 , C07B59/002 , C07B2200/05 , C07D215/42 , C07D401/06 , C07D401/12 , C07D401/14 , C07D405/06 , C07D409/12 , C07D413/06 , C07D413/14 , C07D417/06 , C07D417/12 , C07D417/14 , C07D471/04 , C07D487/04 , C07D498/04 , C07D513/04 , C07D519/00 , C07F5/02 , C07F9/6509
Abstract: The present invention relates to a compound which can be useful for the treatment or prevention of SPT-related diseases including cancer and congenital diseases associated with sphingolipid accumulation (including Niemann-Pick disease).
-
公开(公告)号：US20170016139A1
公开(公告)日：2017-01-19
申请号：US15252626
申请日：2016-08-31
Applicant: Takeda Pharmaceutical Company Limited
Inventor： Bunnai SAITO
IPC: C30B7/14 , C30B29/58 , C08F292/00
CPC classification number: C30B7/14 , C08F292/00 , C30B29/54
Abstract: The present invention provides a method for producing a single crystal of a polymer-metal complex comprising: (a) a step of dissolving in an organic solvent a tridentate ligand represented by formula (1): (wherein, Ar represents an optionally substituted trivalent aromatic group, X1 to X3 each independently represent a divalent organic group, or a single bond that directly bonds Ar and Y1, Y2, or Y3, and Y1 to Y3 each independently represent a monovalent organic group having a coordinating moiety); and (b) a step of obtaining the single crystal of the polymer-metal complex by adding to the solution obtained in step (a) a compound for providing the metal ion and an additive for changing solution properties to basic.
-
公开(公告)号：US20190062274A1
公开(公告)日：2019-02-28
申请号：US16175144
申请日：2018-10-30
Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
Inventor： Yasutomi ASANO , Takuto KOJIMA , Osamu KURASAWA , Tzu-Tshin WONG , Yasuhiro HIRATA , Naoki IWAMURA , Bunnai SAITO , Yuta TANAKA , Ryosuke ARAI , Shinichi IMAMURA , Kazuko YONEMORI , Yasufumi MIYAMOTO , Shuji KITAMURA , Osamu SANO
IPC: C07D211/58 , C07F9/6509 , C07D405/06 , A61P3/00 , A61P35/00 , C07B59/00 , C07D413/14 , C07F5/02 , C07D519/00 , C07D513/04 , C07D498/04 , C07D487/04 , C07D471/04 , C07D417/14 , C07D417/12 , C07D417/06 , C07D413/06 , C07D409/12 , C07D401/12 , C07D401/06 , C07D215/42 , A61K33/22 , A61K31/661 , A61K31/5355 , A61K31/517 , A61K31/506 , A61K31/498 , A61K31/4709 , A61K31/452 , A61K31/451 , A61K31/4468 , A61K31/444 , A61K31/4439 , A61K31/4436 , A61K31/4433 , A61K31/443 , A61K31/437 , C07D401/14
CPC classification number: C07D211/58 , A61K31/437 , A61K31/443 , A61K31/4433 , A61K31/4436 , A61K31/4439 , A61K31/444 , A61K31/4468 , A61K31/451 , A61K31/452 , A61K31/4709 , A61K31/498 , A61K31/506 , A61K31/517 , A61K31/5355 , A61K31/661 , A61K33/22 , A61P3/00 , A61P35/00 , C07B59/002 , C07B2200/05 , C07D215/42 , C07D401/06 , C07D401/12 , C07D401/14 , C07D405/06 , C07D409/12 , C07D413/06 , C07D413/14 , C07D417/06 , C07D417/12 , C07D417/14 , C07D471/04 , C07D487/04 , C07D498/04 , C07D513/04 , C07D519/00 , C07F5/02 , C07F9/6509 , Y02P20/55
Abstract: The present invention relates to a compound which can be useful for the treatment or prevention of SPT-related diseases including cancer and congenital diseases associated with sphingolipid accumulation (including Niemann-Pick disease).
-
-
Search Results
3
records
(took 0.024 seconds)
