Patent search ap:("TAKEDA PHARMACEUTICAL COMPANY LIMITED") AND inv:"Naoki IWAMURA" Page 1

1.

发明申请
FUSED HETEROCYCLIC COMPOUND 有权
Title translation: 熔融杂环化合物

公开(公告)号：US20170037057A1

公开(公告)日：2017-02-09

申请号：US15304727

申请日：2015-04-16

Applicant: Takeda Pharmaceutical Company Limited

Inventor： Masanori Okaniwa , Hiroshi BANNO , Takaharu HIRAYAMA , Douglas Robert CARY , Koji ONO , Naoki IWAMURA

IPC: C07D513/04

CPC classification number: C07D513/04 , A61K31/429 , A61K31/433 , A61K31/4439 , A61K31/444 , A61K31/4545 , A61K31/455 , A61K31/5377

Abstract: The present invention provides a fused heterocyclic compound that has CDK 8 and/or CDK 19 inhibitory activity. The present invention provides a compound represented by formula (I) (wherein the symbols are as defined in the description) or a salt thereof.

Abstract translation: （其中符号如说明书中所定义）或其盐。

2.

发明申请
HETEROCYCLIC AMIDE COMPOUND 审中-公开

公开(公告)号：US20190241566A1

公开(公告)日：2019-08-08

申请号：US16333296

申请日：2017-09-14

Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED

Inventor： Takaharu HIRAYAMA , Yasuhiro HIRATA , Yusuke TOMINARI , Naoki IWAMURA , Yusuke SASAKI , Moriteru ASANO , Terufumi TAKAGI , Masanori OKANIWA , Masato YOSHIDA , Takashi ICHIKAWA , Shinichi IMAMURA

IPC: C07D473/28 , C07D473/40 , C07D519/00 , C07D471/04 , C07D417/14 , C07D413/14 , C07D401/14 , C07D409/14 , C07D405/14 , C07D401/04 , A61P35/00

Abstract: Provided is a heterocyclic amide compound that may have a PRS inhibitory action and is expected to be useful as a prophylactic or therapeutic agent for PRS associated diseases and the like including cancer. A compound represented by the following formula (I): wherein a group represented by is a group represented by the following formula (II) or the following formula (III): and other symbols are as described in the DESCRIPTION, or a salt thereof.

3.

发明申请
HETEROCYCLIC COMPOUND 审中-公开

公开(公告)号：US20180170874A1

公开(公告)日：2018-06-21

申请号：US15565891

申请日：2016-04-19

Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED

Inventor： Yasutomi ASANO , Takuto KOJIMA , Osamu KURASAWA , Tzu-Tshin WONG , Yasuhiro HIRATA , Naoki IWAMURA , Bunnai SAITO , Yuta TANAKA , Ryosuke ARAI , Shinichi IMAMURA , Kazuko YONEMORI , Yasufumi MIYAMOTO , Shuji KITAMURA , Osamu SANO

IPC: C07D211/58 , C07D471/04 , C07D498/04 , C07D513/04 , C07D519/00 , C07D215/42 , C07D401/12 , C07D417/12 , C07D405/06 , C07D413/06 , C07D401/06 , C07D417/06 , C07D401/14 , C07D417/14 , C07D413/14 , C07B59/00 , A61P35/00 , A61P3/00

CPC classification number: C07D211/58 , A61K31/437 , A61K31/443 , A61K31/4433 , A61K31/4436 , A61K31/4439 , A61K31/444 , A61K31/4468 , A61K31/451 , A61K31/452 , A61K31/4709 , A61K31/498 , A61K31/506 , A61K31/517 , A61K31/5355 , A61K31/661 , A61K33/22 , A61P3/00 , A61P35/00 , C07B59/002 , C07B2200/05 , C07D215/42 , C07D401/06 , C07D401/12 , C07D401/14 , C07D405/06 , C07D409/12 , C07D413/06 , C07D413/14 , C07D417/06 , C07D417/12 , C07D417/14 , C07D471/04 , C07D487/04 , C07D498/04 , C07D513/04 , C07D519/00 , C07F5/02 , C07F9/6509

Abstract: The present invention relates to a compound which can be useful for the treatment or prevention of SPT-related diseases including cancer and congenital diseases associated with sphingolipid accumulation (including Niemann-Pick disease).

4.

发明申请
HETEROCYCLIC AMIDE COMPOUND 审中-公开

公开(公告)号：US20190359587A1

公开(公告)日：2019-11-28

申请号：US16332993

申请日：2017-09-14

Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED

Inventor： Takaharu HIRAYAMA , Yasuhiro HIRATA , Yusuke TOMINARI , Naoki IWAMURA , Yusuke SASAKI , Moriteru ASANO , Terufumi TAKAGI , Masanori OKANIWA , Masato YOSHIDA , Shinichi IMAMURA

IPC: C07D401/04 , A61P35/00 , C07D409/14 , C07D401/14 , C07D417/14 , C07D407/14

Abstract: Provided is a heterocyclic amide compound that may have a PRS inhibitory action and is expected to be useful as a prophylactic or therapeutic agent for PRS associated diseases and the like including cancer. A compound represented by the following formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof.